WO2002016396A3 - Mammalian rh type b glycoprotein ion transporter - Google Patents

Mammalian rh type b glycoprotein ion transporter Download PDF

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Publication number
WO2002016396A3
WO2002016396A3 PCT/US2001/025881 US0125881W WO0216396A3 WO 2002016396 A3 WO2002016396 A3 WO 2002016396A3 US 0125881 W US0125881 W US 0125881W WO 0216396 A3 WO0216396 A3 WO 0216396A3
Authority
WO
WIPO (PCT)
Prior art keywords
rhbg
glycoprotein
glycoproteins
acid sequences
nucleic acid
Prior art date
Application number
PCT/US2001/025881
Other languages
French (fr)
Other versions
WO2002016396A2 (en
WO2002016396A9 (en
WO2002016396A8 (en
Inventor
Cheng-Han Huang
Zhi Liu
Original Assignee
New York Blood Ct Inc
Cheng-Han Huang
Zhi Liu
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by New York Blood Ct Inc, Cheng-Han Huang, Zhi Liu filed Critical New York Blood Ct Inc
Priority to AU2001285060A priority Critical patent/AU2001285060A1/en
Publication of WO2002016396A2 publication Critical patent/WO2002016396A2/en
Publication of WO2002016396A8 publication Critical patent/WO2002016396A8/en
Publication of WO2002016396A9 publication Critical patent/WO2002016396A9/en
Publication of WO2002016396A3 publication Critical patent/WO2002016396A3/en

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

The present invention provides nucleic acid sequences encoding novel mammalian nonerythroid Rh glycoprotein homologues, Rhbg including the human homologue RhBG. These RhBG, Rhbg glycoproteins are polytypic transporter-type proteins with 12 transmembrane domains and are predominantly expressed as a single major form in kidney, and as multiple forms in liver, skin and ovaries. Also provided are recombinant vectors and host vector systems containing these nucleic acid sequences, as well as fusion proteins incorporating Rhbg, RhBG or fragments of each. The invention further provides methods of detection of Rhbg and RhBG glycoproteins and also methods of detecting nucleic acids encoding Rhbg and RhBG.
PCT/US2001/025881 2000-08-21 2001-08-17 Mammalian rh type b glycoprotein ion transporter WO2002016396A2 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU2001285060A AU2001285060A1 (en) 2000-08-21 2001-08-17 Mammalian rh type b glycoprotein ion transporter

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US22676700P 2000-08-21 2000-08-21
US60/226,767 2000-08-21

Publications (4)

Publication Number Publication Date
WO2002016396A2 WO2002016396A2 (en) 2002-02-28
WO2002016396A8 WO2002016396A8 (en) 2002-08-29
WO2002016396A9 WO2002016396A9 (en) 2002-09-26
WO2002016396A3 true WO2002016396A3 (en) 2002-12-27

Family

ID=22850317

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US2001/025881 WO2002016396A2 (en) 2000-08-21 2001-08-17 Mammalian rh type b glycoprotein ion transporter

Country Status (2)

Country Link
AU (1) AU2001285060A1 (en)
WO (1) WO2002016396A2 (en)

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999037763A2 (en) * 1998-01-23 1999-07-29 Drk Blutspendedienst Baden-Wuerttemberg Ggmbh Novel nucleic acid molecules correlated with the rhesus weak d phenotype

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999037763A2 (en) * 1998-01-23 1999-07-29 Drk Blutspendedienst Baden-Wuerttemberg Ggmbh Novel nucleic acid molecules correlated with the rhesus weak d phenotype

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
LIU ET AL.: "Rh type B glycoprotein is a new member of the Rh superfamily and a putative ammonia transporter in mammals", JOURNAL BIOL. CHEM., vol. 276, no. 2, 12 January 2001 (2001-01-12), pages 1424 - 1433, XP002952388 *

Also Published As

Publication number Publication date
WO2002016396A2 (en) 2002-02-28
AU2001285060A1 (en) 2002-03-04
WO2002016396A9 (en) 2002-09-26
WO2002016396A8 (en) 2002-08-29

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