WO2001036485A3 - Anticuerpo monocolonal recombinante que reconoce el antigeno ior c2 su uso para el diagnostico y tratamiento de tumores colorectales - Google Patents
Anticuerpo monocolonal recombinante que reconoce el antigeno ior c2 su uso para el diagnostico y tratamiento de tumores colorectales Download PDFInfo
- Publication number
- WO2001036485A3 WO2001036485A3 PCT/CU2000/000004 CU0000004W WO0136485A3 WO 2001036485 A3 WO2001036485 A3 WO 2001036485A3 CU 0000004 W CU0000004 W CU 0000004W WO 0136485 A3 WO0136485 A3 WO 0136485A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- diagnosis
- treatment
- monoclonal antibodies
- colorectal tumors
- ior
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
- C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
- C07K16/3046—Stomach, Intestines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
- G01N33/57407—Specifically defined cancers
- G01N33/57446—Specifically defined cancers of stomach or intestine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
- C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2317/00—Immunoglobulins specific features
- C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
- C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
- C07K2317/622—Single chain antibody (scFv)
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N2800/00—Detection or diagnosis of diseases
- G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Urology & Nephrology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- Cell Biology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biotechnology (AREA)
- Analytical Chemistry (AREA)
- Hospice & Palliative Care (AREA)
- Pathology (AREA)
- Microbiology (AREA)
- Oncology (AREA)
- General Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Physics & Mathematics (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Peptides Or Proteins (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Abstract
Priority Applications (9)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CA002359577A CA2359577A1 (en) | 1999-11-16 | 2000-11-16 | Antibodies and fv fragment recognizing antigen ior c2 |
AU15130/01A AU783622B2 (en) | 1999-11-16 | 2000-11-16 | Antibodies and FV fragment recognizing antigen IOR C2 |
EP00977398A EP1174441A2 (en) | 1999-11-16 | 2000-11-16 | Antibodies and fv fragment recognizing antigen ior c2 |
MXPA01007261A MXPA01007261A (es) | 1999-11-16 | 2000-11-16 | Anticuerpos y fragmentos fv que reconocen el antigeno ior c2. |
EA200100782A EA005169B1 (ru) | 1999-11-16 | 2000-11-16 | РЕКОМБИНАНТНОЕ АНТИТЕЛО, ВЗАИМОДЕЙСТВУЮЩЕЕ С АНТИГЕННЫМ КОМПЛЕКСОМ IOR C2, Fv- ФРАГМЕНТ УКАЗАННОГО АНТИТЕЛА И СПОСОБЫ ИХ ПРИМЕНЕНИЯ |
JP2001538974A JP2003514831A (ja) | 1999-11-16 | 2000-11-16 | 抗原IORC2を認識する抗体およびFvフラグメント |
US09/889,480 US6891023B1 (en) | 1999-11-16 | 2000-11-16 | Antibodies and Fv fragment recognizing antigen IOR C2 |
BR0007827-1A BR0007827A (pt) | 1999-11-16 | 2000-11-16 | Anticorpos e fragmento fv que reconhecemantìgeno ior c2 |
KR1020017008965A KR100827627B1 (ko) | 1999-11-16 | 2000-11-16 | 항원 아이오알 시2를 인식하는 항체 및 에프브이 단편 |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CU196/99 | 1999-11-16 | ||
CU1999196A CU22921A1 (es) | 1999-11-16 | 1999-11-16 | Anticuerpos quimérico, humanizado y el fragmento de tipo fv de cadena sencilla que reconoce el antígeno c2. su uso en el diagnóstico y tratamiento de tumores colorrectales |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2001036485A2 WO2001036485A2 (es) | 2001-05-25 |
WO2001036485A3 true WO2001036485A3 (es) | 2001-11-08 |
Family
ID=5459527
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/CU2000/000004 WO2001036485A2 (es) | 1999-11-16 | 2000-11-16 | Anticuerpo monocolonal recombinante que reconoce el antigeno ior c2 su uso para el diagnostico y tratamiento de tumores colorectales |
Country Status (16)
Country | Link |
---|---|
US (1) | US6891023B1 (es) |
EP (1) | EP1174441A2 (es) |
JP (1) | JP2003514831A (es) |
KR (1) | KR100827627B1 (es) |
CN (1) | CN1230446C (es) |
AR (1) | AR026463A1 (es) |
AU (1) | AU783622B2 (es) |
BR (1) | BR0007827A (es) |
CA (1) | CA2359577A1 (es) |
CO (1) | CO5280154A1 (es) |
CU (1) | CU22921A1 (es) |
EA (1) | EA005169B1 (es) |
MX (1) | MXPA01007261A (es) |
TW (1) | TWI233440B (es) |
WO (1) | WO2001036485A2 (es) |
ZA (1) | ZA200105803B (es) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0228832D0 (en) | 2002-12-10 | 2003-01-15 | Novartis Ag | Organic compound |
MX2008010942A (es) * | 2006-02-28 | 2008-09-03 | Nymox Corp | Peptidos efectivos en el tratamiento de tumores y otras condiciones que requieren la remocion o destruccion de celulas. |
WO2012147965A1 (ja) * | 2011-04-28 | 2012-11-01 | 独立行政法人理化学研究所 | 生物材料を透明化する方法、及びその利用 |
JP6044900B2 (ja) | 2011-05-20 | 2016-12-14 | 国立研究開発法人理化学研究所 | 生物材料用透明化試薬、及びその利用 |
WO2015022883A1 (ja) | 2013-08-14 | 2015-02-19 | 独立行政法人理化学研究所 | 光透過性に優れた生物材料を調製するための組成物およびその利用 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1997033916A1 (es) * | 1996-03-12 | 1997-09-18 | Centro De Inmunologia Molecular (Cim) | Anticuerpos monoclonales ior c5 para el diagnostico y tratamiento de tumores colorrectales |
US5712120A (en) * | 1994-06-30 | 1998-01-27 | Centro De Immunologia Molecular | Method for obtaining modified immunoglobulins with reduced immunogenicity of murine antibody variable domains, compositions containing them |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8928874D0 (en) * | 1989-12-21 | 1990-02-28 | Celltech Ltd | Humanised antibodies |
DE69704702T2 (de) | 1996-03-07 | 2001-11-29 | Agfa Gevaert Nv | Gerät zur entwicklung von photographischem blattmaterial |
-
1999
- 1999-11-16 CU CU1999196A patent/CU22921A1/es unknown
-
2000
- 2000-11-14 AR ARP000105994A patent/AR026463A1/es active IP Right Grant
- 2000-11-16 EP EP00977398A patent/EP1174441A2/en not_active Ceased
- 2000-11-16 CO CO00087150A patent/CO5280154A1/es active IP Right Grant
- 2000-11-16 JP JP2001538974A patent/JP2003514831A/ja active Pending
- 2000-11-16 BR BR0007827-1A patent/BR0007827A/pt not_active Application Discontinuation
- 2000-11-16 MX MXPA01007261A patent/MXPA01007261A/es active IP Right Grant
- 2000-11-16 CN CNB008039542A patent/CN1230446C/zh not_active Expired - Fee Related
- 2000-11-16 EA EA200100782A patent/EA005169B1/ru not_active IP Right Cessation
- 2000-11-16 AU AU15130/01A patent/AU783622B2/en not_active Ceased
- 2000-11-16 US US09/889,480 patent/US6891023B1/en not_active Expired - Fee Related
- 2000-11-16 KR KR1020017008965A patent/KR100827627B1/ko not_active IP Right Cessation
- 2000-11-16 CA CA002359577A patent/CA2359577A1/en not_active Abandoned
- 2000-11-16 WO PCT/CU2000/000004 patent/WO2001036485A2/es active Application Filing
-
2001
- 2001-01-30 TW TW089126622A patent/TWI233440B/zh not_active IP Right Cessation
- 2001-07-13 ZA ZA200105803A patent/ZA200105803B/en unknown
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5712120A (en) * | 1994-06-30 | 1998-01-27 | Centro De Immunologia Molecular | Method for obtaining modified immunoglobulins with reduced immunogenicity of murine antibody variable domains, compositions containing them |
WO1997033916A1 (es) * | 1996-03-12 | 1997-09-18 | Centro De Inmunologia Molecular (Cim) | Anticuerpos monoclonales ior c5 para el diagnostico y tratamiento de tumores colorrectales |
Non-Patent Citations (4)
Title |
---|
JONES P T ET AL: "Replacing the complementarity-determining regions in a human antibody with those from a mouse", NATURE, vol. 321, 29 May 1986 (1986-05-29), pages 522 - 525, XP002901661 * |
RIECHMANN L ET AL: "Reshaping human antibodies for therapy", NATURE, vol. 332, 24 March 1988 (1988-03-24), pages 323 - 327, XP002901660 * |
See also references of EP1174441A2 * |
VAZQUEZ A ET AL: "Characterization of ior C5 colorectal tumor associated antigen", INMUNOLOGIA, vol. 14, no. 3, 1995, pages 130 - 132, XP002901659 * |
Also Published As
Publication number | Publication date |
---|---|
AU783622B2 (en) | 2005-11-17 |
MXPA01007261A (es) | 2002-06-04 |
AR026463A1 (es) | 2003-02-12 |
CU22921A1 (es) | 2004-02-20 |
EP1174441A2 (en) | 2002-01-23 |
US6891023B1 (en) | 2005-05-10 |
CO5280154A1 (es) | 2003-05-30 |
KR100827627B1 (ko) | 2008-05-07 |
EA200100782A1 (ru) | 2002-02-28 |
CN1344276A (zh) | 2002-04-10 |
KR20020008113A (ko) | 2002-01-29 |
CN1230446C (zh) | 2005-12-07 |
CA2359577A1 (en) | 2001-05-25 |
ZA200105803B (en) | 2003-01-06 |
WO2001036485A2 (es) | 2001-05-25 |
BR0007827A (pt) | 2001-10-30 |
TWI233440B (en) | 2005-06-01 |
JP2003514831A (ja) | 2003-04-22 |
EA005169B1 (ru) | 2004-12-30 |
AU1513001A (en) | 2001-05-30 |
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