CO5280154A1 - Anticuerpos y fragmento fv que reconocen el antigeno ior c2 - Google Patents

Anticuerpos y fragmento fv que reconocen el antigeno ior c2

Info

Publication number
CO5280154A1
CO5280154A1 CO00087150A CO00087150A CO5280154A1 CO 5280154 A1 CO5280154 A1 CO 5280154A1 CO 00087150 A CO00087150 A CO 00087150A CO 00087150 A CO00087150 A CO 00087150A CO 5280154 A1 CO5280154 A1 CO 5280154A1
Authority
CO
Colombia
Prior art keywords
ior
antibodies
antibody
fragment
recognizing
Prior art date
Application number
CO00087150A
Other languages
English (en)
Inventor
De Acosta Del Rio Cristina Maria Mateo
Navarro Lourdes Tatiana Roque
Morales Alejo Morales
Rodriguez Rolando Perez
Avila Marta Ayala
Cowley Jorge Victor Gavilondo
Porto Marta Duenas
Garcia Hanssel Bell
Calzado Enrique Rengifo
Normando Iznaga Escobar
Zuzarte Mayra Ramos
Original Assignee
Centro Inmunologia Molecular
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Centro Inmunologia Molecular filed Critical Centro Inmunologia Molecular
Publication of CO5280154A1 publication Critical patent/CO5280154A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3046—Stomach, Intestines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574—Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57407—Specifically defined cancers
    • G01N33/57446—Specifically defined cancers of stomach or intestine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/60—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments
    • C07K2317/62—Immunoglobulins specific features characterized by non-natural combinations of immunoglobulin fragments comprising only variable region components
    • C07K2317/622—Single chain antibody (scFv)
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2800/00—Detection or diagnosis of diseases
    • G01N2800/52—Predicting or monitoring the response to treatment, e.g. for selection of therapy based on assay results in personalised medicine; Prognosis

Abstract

Anticuerpo recombinante y fragmento de tipo Fv de cadena sencilla derivados del anticuerpo monoclonal murino IOR C5 producido por el hibridoma con número de depósito ECCC 97061101, donde dicho anticuerpo recombinante contiene las Regiones Determinantes de la Complementariedad (CDRs) del anticuerpo IOR C5 y regiones constantes humanas en las cadenas pesadas y ligeras.Composición farmacéutica para el tratamiento de tumores malignos de colon y recto, sus metástasis y recidivas que contiene uno de los anticuerpos recombinantes de las reivindicaciones de la 1 a la 5, y un excipiente apropiado para su aplicación.
CO00087150A 1999-11-16 2000-11-16 Anticuerpos y fragmento fv que reconocen el antigeno ior c2 CO5280154A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CU1999196A CU22921A1 (es) 1999-11-16 1999-11-16 Anticuerpos quimérico, humanizado y el fragmento de tipo fv de cadena sencilla que reconoce el antígeno c2. su uso en el diagnóstico y tratamiento de tumores colorrectales

Publications (1)

Publication Number Publication Date
CO5280154A1 true CO5280154A1 (es) 2003-05-30

Family

ID=5459527

Family Applications (1)

Application Number Title Priority Date Filing Date
CO00087150A CO5280154A1 (es) 1999-11-16 2000-11-16 Anticuerpos y fragmento fv que reconocen el antigeno ior c2

Country Status (16)

Country Link
US (1) US6891023B1 (es)
EP (1) EP1174441A2 (es)
JP (1) JP2003514831A (es)
KR (1) KR100827627B1 (es)
CN (1) CN1230446C (es)
AR (1) AR026463A1 (es)
AU (1) AU783622B2 (es)
BR (1) BR0007827A (es)
CA (1) CA2359577A1 (es)
CO (1) CO5280154A1 (es)
CU (1) CU22921A1 (es)
EA (1) EA005169B1 (es)
MX (1) MXPA01007261A (es)
TW (1) TWI233440B (es)
WO (1) WO2001036485A2 (es)
ZA (1) ZA200105803B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0228832D0 (en) * 2002-12-10 2003-01-15 Novartis Ag Organic compound
CN101389760A (zh) * 2006-02-28 2009-03-18 尼莫克斯股份有限公司 有效治疗肿瘤或其他需要除去或破坏细胞的病症的肽
JP5924624B2 (ja) * 2011-04-28 2016-05-25 国立研究開発法人理化学研究所 生物材料を透明化する方法、及びその利用
CN103562702A (zh) 2011-05-20 2014-02-05 独立行政法人理化学研究所 生物材料用透明化试剂、及其利用
EP3035026A4 (en) 2013-08-14 2017-04-26 Riken Composition for preparing biomaterial with excellent light-transmitting property, and use thereof

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8928874D0 (en) * 1989-12-21 1990-02-28 Celltech Ltd Humanised antibodies
CU22615A1 (es) 1994-06-30 2000-02-10 Centro Inmunologia Molecular Procedimiento de obtención de anticuerpos monoclonales murinos menos inmunogénicos. anticuerpos monoclonales obtenidos
EP0885404B1 (en) 1996-03-07 2001-05-02 Agfa-Gevaert N.V. Apparatus for the processing of photographic sheet material
CU22640A1 (es) * 1996-03-12 2000-12-22 Centro Inmunologia Molecular Composición farmacéutica y kit que contienen anticuerpos monoclonales para marcaje con isótopos radioactivos. sus usos para el diagnóstico y tratamiento de tumores colorrectales, sus metástasis y recidivas

Also Published As

Publication number Publication date
EA200100782A1 (ru) 2002-02-28
KR100827627B1 (ko) 2008-05-07
US6891023B1 (en) 2005-05-10
AR026463A1 (es) 2003-02-12
CN1230446C (zh) 2005-12-07
AU783622B2 (en) 2005-11-17
AU1513001A (en) 2001-05-30
EA005169B1 (ru) 2004-12-30
EP1174441A2 (en) 2002-01-23
BR0007827A (pt) 2001-10-30
CA2359577A1 (en) 2001-05-25
MXPA01007261A (es) 2002-06-04
WO2001036485A2 (es) 2001-05-25
WO2001036485A3 (es) 2001-11-08
KR20020008113A (ko) 2002-01-29
CN1344276A (zh) 2002-04-10
JP2003514831A (ja) 2003-04-22
CU22921A1 (es) 2004-02-20
ZA200105803B (en) 2003-01-06
TWI233440B (en) 2005-06-01

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Legal Events

Date Code Title Description
FG Application granted