WO2001011052A3 - Ein- oder mehrzellige organismen zur herstellung von riboflavin - Google Patents

Ein- oder mehrzellige organismen zur herstellung von riboflavin Download PDF

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Publication number
WO2001011052A3
WO2001011052A3 PCT/EP2000/007370 EP0007370W WO0111052A3 WO 2001011052 A3 WO2001011052 A3 WO 2001011052A3 EP 0007370 W EP0007370 W EP 0007370W WO 0111052 A3 WO0111052 A3 WO 0111052A3
Authority
WO
WIPO (PCT)
Prior art keywords
monocellular
riboflavin
production
multicellular organisms
nad
Prior art date
Application number
PCT/EP2000/007370
Other languages
English (en)
French (fr)
Other versions
WO2001011052A2 (de
Inventor
Henning Althoefer
Oskar Zelder
Doval Jose L Revuelta
Garcia Maria Angeles Santos
Hermann Sahm
Klaus-Peter Stahmann
Ines Maeting
Original Assignee
Basf Ag
Forschungszentrum Juelich Gmbh
Henning Althoefer
Oskar Zelder
Doval Jose L Revuelta
Garcia Maria Angeles Santos
Hermann Sahm
Stahmann Klaus Peter
Ines Maeting
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Ag, Forschungszentrum Juelich Gmbh, Henning Althoefer, Oskar Zelder, Doval Jose L Revuelta, Garcia Maria Angeles Santos, Hermann Sahm, Stahmann Klaus Peter, Ines Maeting filed Critical Basf Ag
Priority to KR1020027001673A priority Critical patent/KR20020033757A/ko
Priority to EP00956355A priority patent/EP1200600A2/de
Priority to AU68331/00A priority patent/AU6833100A/en
Priority to JP2001515837A priority patent/JP2003506090A/ja
Publication of WO2001011052A2 publication Critical patent/WO2001011052A2/de
Publication of WO2001011052A3 publication Critical patent/WO2001011052A3/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/14—Fungi; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P25/00—Preparation of compounds containing alloxazine or isoalloxazine nucleus, e.g. riboflavin

Abstract

Die vorliegende Erfindung betrifft einen ein- oder mehrzelligen Organismus, insbesondere Mikroorganismus, zur biotechnischen Herstellung von Riboflavin, wobei dessen Enzymaktivität bezüglich der NAD(P)H Bildung höher ist als derjenige eines Wildtyps der Species Ashbya gossypii ATCC10895.
PCT/EP2000/007370 1999-08-09 2000-07-31 Ein- oder mehrzellige organismen zur herstellung von riboflavin WO2001011052A2 (de)

Priority Applications (4)

Application Number Priority Date Filing Date Title
KR1020027001673A KR20020033757A (ko) 1999-08-09 2000-07-31 리보플라빈 생산을 위한 단세포 또는 다세포 생물체
EP00956355A EP1200600A2 (de) 1999-08-09 2000-07-31 Ein- oder mehrzellige organismen zur herstellung von riboflavin
AU68331/00A AU6833100A (en) 1999-08-09 2000-07-31 Monocellular or multicellular organisms for the production of riboflavin
JP2001515837A JP2003506090A (ja) 1999-08-09 2000-07-31 リボフラビンを製造するための単細胞生物または多細胞生物

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19937548A DE19937548A1 (de) 1999-08-09 1999-08-09 Ein- oder mehrzellige Organismen zur Herstellung von Riboflavin
DE19937548.8 1999-08-09

Publications (2)

Publication Number Publication Date
WO2001011052A2 WO2001011052A2 (de) 2001-02-15
WO2001011052A3 true WO2001011052A3 (de) 2001-07-05

Family

ID=7917735

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2000/007370 WO2001011052A2 (de) 1999-08-09 2000-07-31 Ein- oder mehrzellige organismen zur herstellung von riboflavin

Country Status (7)

Country Link
EP (1) EP1200600A2 (de)
JP (1) JP2003506090A (de)
KR (1) KR20020033757A (de)
CN (1) CN1369013A (de)
AU (1) AU6833100A (de)
DE (1) DE19937548A1 (de)
WO (1) WO2001011052A2 (de)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PT2164975E (pt) 2007-07-06 2012-03-08 Basf Se Processo para a produção de uma solução aquosa de glicose

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0405370A1 (de) * 1989-06-22 1991-01-02 F. Hoffmann-La Roche Ag Riboflavin À¼berproduzierende Bakterienstämme
WO1997003208A1 (de) * 1995-07-13 1997-01-30 Basf Aktiengesellschaft Verfahren zur herstellung von riboflavin mittels mikroorganismen mit veränderter isocitratlyase-aktivität
EP0927761A2 (de) * 1997-12-23 1999-07-07 Basf Aktiengesellschaft Gene der Purinbiosyntese aus Ashbya gossypii und deren Verwendung in der mikrobiellen Riboflavinsynthese

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0405370A1 (de) * 1989-06-22 1991-01-02 F. Hoffmann-La Roche Ag Riboflavin À¼berproduzierende Bakterienstämme
WO1997003208A1 (de) * 1995-07-13 1997-01-30 Basf Aktiengesellschaft Verfahren zur herstellung von riboflavin mittels mikroorganismen mit veränderter isocitratlyase-aktivität
EP0927761A2 (de) * 1997-12-23 1999-07-07 Basf Aktiengesellschaft Gene der Purinbiosyntese aus Ashbya gossypii und deren Verwendung in der mikrobiellen Riboflavinsynthese

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
HENKE BIRGIT ET AL: "IDP3 encodes a peroxisomal NADP-dependent isocitrate dehydrogenase required for the beta-oxidation of unsaturated fatty acids.", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 273, no. 6, 6 February 1998 (1998-02-06), pages 3702 - 3711, XP002157778, ISSN: 0021-9258 *

Also Published As

Publication number Publication date
KR20020033757A (ko) 2002-05-07
DE19937548A1 (de) 2001-03-29
WO2001011052A2 (de) 2001-02-15
CN1369013A (zh) 2002-09-11
JP2003506090A (ja) 2003-02-18
EP1200600A2 (de) 2002-05-02
AU6833100A (en) 2001-03-05

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