WO2001016303A3 - Nucleinsäuren, die für enzymaktivitäten der spinosyn-biosynthese codieren - Google Patents

Nucleinsäuren, die für enzymaktivitäten der spinosyn-biosynthese codieren Download PDF

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Publication number
WO2001016303A3
WO2001016303A3 PCT/EP2000/008013 EP0008013W WO0116303A3 WO 2001016303 A3 WO2001016303 A3 WO 2001016303A3 EP 0008013 W EP0008013 W EP 0008013W WO 0116303 A3 WO0116303 A3 WO 0116303A3
Authority
WO
WIPO (PCT)
Prior art keywords
code
nucleic acids
enzyme activities
spinosyn
spinosyn biosynthesis
Prior art date
Application number
PCT/EP2000/008013
Other languages
English (en)
French (fr)
Other versions
WO2001016303A2 (de
Inventor
Guenther Eberz
Volker Moehrle
Rita Froede
Robert Velten
Jose A Salas
Original Assignee
Guenther Eberz
Volker Moehrle
Rita Froede
Robert Velten
Jose A Salas
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE19957268A external-priority patent/DE19957268A1/de
Application filed by Guenther Eberz, Volker Moehrle, Rita Froede, Robert Velten, Jose A Salas, Bayer Ag filed Critical Guenther Eberz
Priority to AU68393/00A priority Critical patent/AU6839300A/en
Priority to EP00956458A priority patent/EP1212412A2/de
Priority to JP2001520850A priority patent/JP2003508050A/ja
Priority to US10/069,353 priority patent/US7285653B1/en
Publication of WO2001016303A2 publication Critical patent/WO2001016303A2/de
Publication of WO2001016303A3 publication Critical patent/WO2001016303A3/de

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/44—Preparation of O-glycosides, e.g. glucosides
    • C12P19/60—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin
    • C12P19/62—Preparation of O-glycosides, e.g. glucosides having an oxygen of the saccharide radical directly bound to a non-saccharide heterocyclic ring or a condensed ring system containing a non-saccharide heterocyclic ring, e.g. coumermycin, novobiocin the hetero ring having eight or more ring members and only oxygen as ring hetero atoms, e.g. erythromycin, spiramycin, nystatin
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes

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  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Die vorliegende Erfindung betrifft Nucleinsäuren, die für Enzymaktivitäten der Spinosyn-Biosynthese codieren, sowie die entsprechenden Enzyme per se. Weiterhin betrifft die Erfindung Verfahren zum Herstellen von Spinosyn-Derivaten und -Vorstufen.
PCT/EP2000/008013 1999-08-27 2000-08-17 Nucleinsäuren, die für enzymaktivitäten der spinosyn-biosynthese codieren WO2001016303A2 (de)

Priority Applications (4)

Application Number Priority Date Filing Date Title
AU68393/00A AU6839300A (en) 1999-08-27 2000-08-17 Nucleic acids which code for the enzyme activities of the spinosyn biosynthesis
EP00956458A EP1212412A2 (de) 1999-08-27 2000-08-17 Nucleinsäuren, die für enzymaktivitäten der spinosyn-biosynthese codieren
JP2001520850A JP2003508050A (ja) 1999-08-27 2000-08-17 スピノシン生合成の酵素活性をコードする核酸
US10/069,353 US7285653B1 (en) 1999-08-27 2000-08-17 Nucleic acids which code for the enzyme activities of the spinosyn biosynthesis

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE19940596 1999-08-27
DE19940596.4 1999-08-27
DE19957268A DE19957268A1 (de) 1999-08-27 1999-11-29 Nucleinsäuren, die für Enzymaktivitäten der Spinosyn-Biosynthese kodieren
DE19957268.2 1999-11-29

Publications (2)

Publication Number Publication Date
WO2001016303A2 WO2001016303A2 (de) 2001-03-08
WO2001016303A3 true WO2001016303A3 (de) 2001-08-02

Family

ID=26054726

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP2000/008013 WO2001016303A2 (de) 1999-08-27 2000-08-17 Nucleinsäuren, die für enzymaktivitäten der spinosyn-biosynthese codieren

Country Status (5)

Country Link
US (1) US7285653B1 (de)
EP (1) EP1212412A2 (de)
JP (1) JP2003508050A (de)
AU (1) AU6839300A (de)
WO (1) WO2001016303A2 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6143526A (en) * 1998-03-09 2000-11-07 Baltz; Richard H. Biosynthetic genes for spinosyn insecticide production
TWI237802B (en) 2000-07-31 2005-08-11 Semiconductor Energy Lab Driving method of an electric circuit
AR033022A1 (es) * 2001-03-30 2003-12-03 Dow Agrosciences Llc Genes biosinteticos para la produccion de insecticida de butenilespinosina
DE10135550A1 (de) 2001-07-20 2003-01-30 Bayer Cropscience Ag Verfahren zum Herstellen von neuen Spinosyn-Derivaten
KR101016561B1 (ko) 2002-02-19 2011-02-22 다우 아그로사이언시즈 엘엘씨 신규한 스피노신 생산 폴리케타이드 신타제
DE10301519A1 (de) 2003-01-17 2004-07-29 Bayer Cropscience Ag 9-Ketospinosyn-Derivate
US7893232B2 (en) * 2005-12-09 2011-02-22 Suntory Holdings Limited Lipase
SI2343975T1 (sl) * 2008-09-22 2012-12-31 Entarco Sa Eleftherias & Melpomenis Sestavki s spinosinom proti obraščanju z neželenimi organizmi, postopki za njihovo uporabo in predmeti, zaščiteni pred pritrditvijo organizmov, ki se biološko obraščajo
US9404107B2 (en) 2011-05-03 2016-08-02 Dow Agrosciences Llc Integration of genes into the chromosome of Saccharopolyspora spinosa
EP2520658B1 (de) * 2011-05-03 2015-10-07 Dow AgroSciences LLC Erhöhung der Spinosynherstellung mit sauerstoffbindenden Proteinen
JP2018011518A (ja) * 2016-07-19 2018-01-25 国立大学法人 筑波大学 ストレプトマイセス属微生物用ベクター
CN113755364B (zh) * 2021-08-10 2023-05-09 湖北省生物农药工程研究中心 产多杀菌素的放线菌及其在制备杀虫剂中的应用

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999046387A1 (en) * 1998-03-09 1999-09-16 Dow Agrosciences Llc Biosynthetic genes for spinosyn insecticide production

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5362634A (en) 1989-10-30 1994-11-08 Dowelanco Process for producing A83543 compounds
US5227295A (en) 1991-11-08 1993-07-13 Dowelanco Process for isolating A83543 and its components
US5202242A (en) 1991-11-08 1993-04-13 Dowelanco A83543 compounds and processes for production thereof
US5539089A (en) 1991-11-08 1996-07-23 Dowelanco A83543 aglycones and pseudoglycones
AU685107B2 (en) 1993-03-12 1998-01-15 Dow Agrosciences Llc New A83543 compounds and process for production thereof
DE69622564T2 (de) 1995-06-14 2002-11-07 Dow Agrosciences Llc Synthetische modifizierung von spinosyn-verbindungen

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1999046387A1 (en) * 1998-03-09 1999-09-16 Dow Agrosciences Llc Biosynthetic genes for spinosyn insecticide production

Non-Patent Citations (4)

* Cited by examiner, † Cited by third party
Title
BALTZ R H ET AL: "Molecular genetic methods for improving secondary-metabolite production in actinomycetes", TRENDS IN BIOTECHNOLOGY,GB,ELSEVIER PUBLICATIONS, CAMBRIDGE, vol. 14, no. 7, 1 July 1996 (1996-07-01), pages 245 - 250, XP004035763, ISSN: 0167-7799 *
HOPWOOD D A: "Genetic contributions to understanding polyketid synthases", CHEMICAL REVIEWS,US,AMERICAN CHEMICAL SOCIETY. EASTON, vol. 97, no. 7, November 1997 (1997-11-01), pages 2465 - 2497, XP002130647, ISSN: 0009-2665 *
KIRST, H.A. ET AL.,: "Discovery, Isolation, and Structure Elucidation of a Family of Structurally Unique, Fermentation-Derived Tetracyclic Macrolides.", 1992, BAKER, D.R., FENYES, J.G. AND STEFFENS J.J., AMERICAN CHEMICAL SOCIETY SYMPOSIUM SERIES NR. 504: SYNTHESIS AND CHEMISTRY OF AGROCHEMICALS III. WASHINGTON DC, XP000944494 *
MATSUSHIMA P ET AL: "Conjugal transfer of cosmid DNA from Escherichia coli to Saccharopolyspora spinosa: effects of chromosomal insertions on macrolide A83543 production", GENE,NL,ELSEVIER BIOMEDICAL PRESS. AMSTERDAM, vol. 146, no. 1, 1994, pages 39 - 45, XP002106258, ISSN: 0378-1119 *

Also Published As

Publication number Publication date
JP2003508050A (ja) 2003-03-04
EP1212412A2 (de) 2002-06-12
AU6839300A (en) 2001-03-26
WO2001016303A2 (de) 2001-03-08
US7285653B1 (en) 2007-10-23

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