WO2000062851A1 - Fil-guide d'electrophysiologie et procede de fabrication correspondant - Google Patents

Fil-guide d'electrophysiologie et procede de fabrication correspondant Download PDF

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Publication number
WO2000062851A1
WO2000062851A1 PCT/US2000/010982 US0010982W WO0062851A1 WO 2000062851 A1 WO2000062851 A1 WO 2000062851A1 US 0010982 W US0010982 W US 0010982W WO 0062851 A1 WO0062851 A1 WO 0062851A1
Authority
WO
WIPO (PCT)
Prior art keywords
guidewire
electrophysiology
electrode
core
conductor
Prior art date
Application number
PCT/US2000/010982
Other languages
English (en)
Inventor
Harvey W. Collins
Original Assignee
C.R. Bard, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by C.R. Bard, Inc. filed Critical C.R. Bard, Inc.
Publication of WO2000062851A1 publication Critical patent/WO2000062851A1/fr

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14—Probes or electrodes therefor
    • A61B18/1492—Probes or electrodes therefor having a flexible, catheter-like structure, e.g. for heart ablation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
    • A61M25/09—Guide wires
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
    • A61B17/22—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for
    • A61B2017/22038—Implements for squeezing-off ulcers or the like on the inside of inner organs of the body; Implements for scraping-out cavities of body organs, e.g. bones; Calculus removers; Calculus smashing apparatus; Apparatus for removing obstructions in blood vessels, not otherwise provided for with a guide wire
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00053—Mechanical features of the instrument of device
    • A61B2018/00107—Coatings on the energy applicator
    • A61B2018/00136—Coatings on the energy applicator with polymer
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00315—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for treatment of particular body parts
    • A61B2018/00345—Vascular system
    • A61B2018/00351—Heart
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00571—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body for achieving a particular surgical effect
    • A61B2018/00577—Ablation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B2018/00636—Sensing and controlling the application of energy
    • A61B2018/00773—Sensed parameters
    • A61B2018/00839—Bioelectrical parameters, e.g. ECG, EEG
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B18/00—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body
    • A61B18/04—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating
    • A61B18/12—Surgical instruments, devices or methods for transferring non-mechanical forms of energy to or from the body by heating by passing a current through the tissue to be heated, e.g. high-frequency current
    • A61B18/14—Probes or electrodes therefor
    • A61B2018/1405—Electrodes having a specific shape
    • A61B2018/1435—Spiral
    • A61B2018/1437—Spiral whereby the windings of the spiral touch each other such as to create a continuous surface
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
    • A61M25/09—Guide wires
    • A61M2025/09058—Basic structures of guide wires
    • A61M2025/09083—Basic structures of guide wires having a coil around a core
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/01—Introducing, guiding, advancing, emplacing or holding catheters
    • A61M25/09—Guide wires
    • A61M2025/09108—Methods for making a guide wire

Definitions

  • the invention is directed to catheter guidewires and more particularly an economical electrophysiology guidewire apparatus for maneuvering through a vascular system and a cost-effective method of manufacturing such a guidewire.
  • Electrophysiology (EP) catheters are used for a variety of medical applications to collect data concerning vital organs of interest. These minimally invasive devices are conveniently introduced into a vasculature through an incision and tracked along a guidewire or manually maneuvered into a desired location by a physician. EP catheters are often used to diagnose abnormal heart conditions by sensing electrical signals between respective anode and cathode electrodes at varying locations within the heart. Often called “mapping" the heart, such a technique allows for relatively quick identification of abnormal tissue by sensing abnormal electrical readings caused by such tissue. Other treatments often performed by EP catheters involve ablating abnormal tissue to, for example, destroy undesirable lesions or the like.
  • the catheter generally includes a first spirally wound wire extending the entire axial length of the device and defining a core.
  • a second wire is wound coaxially around the first wire and includes a casing or sheath to house the proximal portion of the catheter.
  • a plurality of spaced apart electrode rings are disposed annularly around respective proximal and distal portions of the second wire.
  • a medial RF electrode ring is slidably secured around the second wire to selectively ablate abnormal tissue.
  • EP guidewires such as those disclosed in U.S. Patent No. 4,922,294, assigned to the assignee of the present invention, and U.S. Patent No. 5,465,732, often include uninsulated multi-filar radioscopic and radiotransparent wires wound spirally around a thin mandrel to effect radioscopic contrasting visible to the physician during imaging.
  • a conventional EP catheter typically tracks the guidewire to carry out a specific treatment.
  • Another distinct disadvantage inherent in conventional EP catheters involves the manufacture of the devices. Generally, this includes the steps of wrapping the respective coiled wires to define a core, and, in a separate operation, individually measuring and mounting the annular electrodes in spaced apart locations. Installation of the electrodes in this manner not only consumes additional man-hours during fabrication, correspondingly raising manufacturing costs, but often adds undesirable girth to the cross-sectional radius of the device.
  • EP guidewires that operate in conjunction with EP catheters typically perform well for fluoroscopic imaging purposes, but like conventional EP catheters, have inherent problems that limit their utility.
  • EP guidewires generally carry no capability for carrying out EP treatments independently of an EP catheter. Consequently, multiple instruments are often used for a single treatment thereby increasing the complexity of the procedure for the physician
  • the guidewire of the present invention provides a relatively small cross- sectional diameter that permits a plurality of such devices to share a single introducer system thereby minimizing the number of incisions required to perform the treatment.
  • the guidewire incorporates a highly manufacturable construction that economically and efficiently establishes the capability for the guidewire of carrying out EP treatments independently of an EP catheter
  • the invention comprises an electrophysiology guidewire including an elongated core and a biocompatible coil mechanism
  • the coil mechanism is disposed helically around the core to define a plurality of windings and formed from at least one conductor covered externally with a layer of insulation
  • the insulation is adapted for selective removal to expose a portion of the at least one conductor to define at least one electrode.
  • the invention comp ⁇ ses a catheter system including a catheter having a formed lumen and a guidewire adapted to shdably engage the catheter lumen
  • the guidewire includes an elongated core and a biocompatible coil mechamsm.
  • the coil mechanism is disposed helically around the core to define a plurality of windings and formed from at least one conductor covered externally with a layer of insulation
  • the insulation is adapted for selective removal to expose a portion of the at least one conductor to define at least one electrode.
  • the invention comp ⁇ ses a method of fabricating an electrophysiology guidewire having at least one electrode
  • the method includes the steps of selecting an elongated core; coiling at least one insulated conductor in a helical relationship around the core to define a plurality of insulated windings; and removing a portion of the insulation from at least one of the windings to define at least one electrode.
  • FIGURE 1 is a side plan view of an electrophysiology guidewire according to one embodiment of the present invention.
  • FIGURE 2 is an enlarged side view of encircled portion 2 identified in FIGURE 1;
  • FIGURE 3 is a radial cross-sectional view along line 3-3 of FIGURE 2;
  • FIGURE 4 is a partial axial cross-sectional view along line 4-4 of FIGURE 3;
  • FIGURE 5 is a partial perspective view of a mandrel for use in a method according to the present invention
  • FIGURE 6 is a radial cross-sectional view along line 6-6 of FIGURE 5;
  • FIGURE 7 is a partial axial view of a partially constructed guidewire according to the method of the present invention.
  • FIGURE 8 is a partial axial cross-sectional view along line 8-8 of FIGURE 7;
  • FIGURE 9 is an enlarged view of encircled portion 9 of FIGURE 8;
  • FIGURE 10 is a partial axial cross-sectional view of the present invention according to a second embodiment;
  • FIGURE 11 is a radial cross-sectional view along line 11-11 of FIGURE 10;
  • FIGURE 12 is partial axial cross-sectional view along line 12-12 of FIGURE
  • FIGURE 13 is a side plan view of a guidewire including an alternative proximal connection device.
  • FIGURE 14 is an axial view along line 14-14 of FIGURE 13.
  • the electrophysiology (EP) guidewire of the present invention incorporates a biocompatible multi-filar coil mechanism 24 wound around an internal core 22 ( Figures 3 and 7) and having independently insulated conductors A, B, C, and D to define respective circuits for supporting respective electrodes #1, #2, #3, and #4 ( Figure 2) formed in the conductors by selectively removing the insulation surrounding each conductor.
  • the guidewire allows a physician to perform EP treatments with a device having a relatively small radial cross-section.
  • the internal core 22 ( Figure 3) comprises an elongated formed mandrel having a relatively small radial cross-section and comprising a moldable monomer or polymer material.
  • the moldability of the mandrel conveniently assists in preventing the multi-filar coil mechanism 24 from shifting during winding.
  • the distal end of the mandrel is formed into a smooth mushroom-shaped tip 26 to safely navigate along vascular walls and the like without damaging tissue surfaces.
  • the mandrel may be cold formed into appropriate shapes to facilitate entry into or stability within targeted anatomical sites such as the His Bundle, the right and left atriums and ventricles, and the coronary sinus, artery, and vein.
  • the multi-filar metallic coil mechanism 24 is disposed spirally around the mandrel 22 with the proximal end secured to an electrode tail assembly 40 ( Figure 1) and the distal end attached flush to the mandrel tip 26.
  • the distal tips of the respective filars are left unterminated as respective bipolar or unipolar electrode tips.
  • the number of poles, or filars A, B, C and D may vary with a corresponding effect on the pitch of the respective coil winding.
  • a quadpolar winding is preferred.
  • the respective coil filars are formed of a ductile and electrically conductive compound, such as Medical Grade Steel (MP-35N), or material under the trademark Elgiloy ® available from Elgiloy, Inc., Elgin, Illinois, or high content platinum with enough tensile strength to remain tightly wound into the desired coil shape.
  • MP-35N Medical Grade Steel
  • Elgiloy ® available from Elgiloy, Inc., Elgin, Illinois
  • high content platinum with enough tensile strength to remain tightly wound into the desired coil shape.
  • the coil mechanism not only provides a unique electrical capability, as will be further described below, but also provides a spring winding construction that offers sufficient stiffness to introduce the guidewire intravenously to the site of interest. Moreover, sufficient flexation is built into the formed coil to prevent undesireable perforations into vascular passage walls and allow intimal contact between the guidewire and the traversed vascular passages.
  • the thin layer of dielectric material 30 disposed around each individual coil filar serves as an important feature for the present invention.
  • the dielectric material preferably polyvinyl formal resin under the trademark Formvar ® available from Monsanto Co., acts to electrically isolate the filars A, B, C and D from one another. This in effect creates respective individual circuit paths defined by the respective filars.
  • the dielectric material is selectively removable to expose portions of the respective conductive filars and define respective electrodes #1, #2, #3, and #4 ( Figure 2) for each respective circuit.
  • the electrode tail assembly 40 comprises a connector apparatus 42 to collect and house the proximal end of the coil mechanism 24 and rout the respective filars A, B, C and D to a plurality of corresponding standard .080 inch jack pins 44.
  • the connector apparatus comprises a rotating female receptacle 46 for sealably terminating the respective filars.
  • the tail assembly connects to a switching box or recorder interface (not shown) for use with a computerized diagnostic system (not shown).
  • fabrication of the guidewire 20 is relatively straightforward and begins with the step of selecting the formed mandrel 22, as shown in Figures 5 and 6.
  • the multi-filar coil mechanism 24 is spirally wound around the mandrel, in a progressively axially advancing direction, from the distal end of the mandrel to the proximal end as shown in Figure 7.
  • the winding step comprises a tension winding technique, wherein a spool of multi-filar wire is wound down the mandrel with the filars in tension to form the coil.
  • a point winding technique may be implemented, wherein the coil is wound from a fixed spool utilizing a diamond-shaped tool, commonly known in the art as a coiling pin, that forms the wire over the mandrel.
  • Coiling pins may be procured from Northern Precise Products Co., Ltd., Japan.
  • the mandrel 22 is a moldable mandrel formed of a polymer material.
  • the filar wires of the coil 24 are substantially prevented from sliding axially along the mandrel after they are wrapped around it.
  • the proximal end of the guidewire is mounted to the tail assembly 40 and the individually isolated filars terminated to the respective contact pins 44.
  • the respective electrodes #1, #2, #3 and #4 ( Figure 2) may be formed in the guidewire by selectively removing portions of the respective filars to expose the conductive material. Because the filars spirally span the entire length of the guidewire, the electrodes may be formed at any location as the particular application requires.
  • the guidewire 20 of the present invention is connected to a monitoring system (not shown) that processes and distributes any information provided by the guidewire electrodes to the physician in real-time.
  • the guidewire is then inserted through an introducer system (not shown) that accesses the vasculature through an incision.
  • an introducer system includes an angiographic catheter having a formed lumen to direct the guidewire to the location of interest. Advancement of the guidewire through the catheter lumen to particular areas may be monitored by tracking the position of one or more of the exposed electrodes.
  • the relatively small radial cross-section of the device allows a plurality of guidewires to be inserted through a single introducer system. This desirably reduces the number of incisions and introducer systems required to adequately perform the treatment.
  • the EP guidewire of the present invention is conveniently adaptable for a variety of diagnostic procedures, for example, as a bipolar phase device or unipolar phase device.
  • a bipolar phase device To operate as a bipolar device, respective pairs of filars, such as A, B, and C, D are designated as anode-cathode pairs.
  • the flexibility of the multi-filar wire gives the operator the option of choosing those pairs that provide optimum amplitude readings during use.
  • the guidewire may be configured to a unipolar device by utilizing a large indifferent back electrode underneath a patient, and designating one or more of the filars as a sensing electrode.
  • the guidewire of the present invention includes features similar to those of the first embodiment and further includes the ability of providing additional electrodes without overaffecting the spring dependent pitch of the multi-filar coil mechanism.
  • additional electrodes may be added to the guidewire by winding an overlapping second multi-filar coil 52 coaxially around all but the distal end of a first multi-filar coil 54.
  • a first set of respective electrodes may be formed in the distally exposed end of the first coil, and a second set of electrodes may be formed anywhere along the length of the second coil. This construction is repeatable with any number of coil layers, subject to the radial limits of the device.
  • any additional coil layers may increase the radial cross-section of the guidewire somewhat, the resulting construction provides a predictably suffer multi-pole device. Moreover, by implementing additional electrodes, the number of guidewires required to perform a multi-pole treatment often will be reduced, more than compensating for any additional girth.
  • a significant feature involves the electrically isolated nature of the respective filars.
  • the filars define respective circuit paths for a plurality of selectively formable sensors or electrodes. This construction enables the guidewire to carry out certain EP treatments without the necessity of a corresponding EP catheter having a much larger radial cross-section.
  • the selectively removable insulation also allows for efficient and low cost fabrication of a multi-pole device. Respective poles, or electrodes are then realized by conveniently removing portions of the insulation from the respective filars to expose the conductive material underneath.
  • the relatively small radial cross-section of the guidewire allows a plurality of guidewires to be inserted into the vasculature through a single introducer system. This not only eliminates the need to make multiple incisions, but also reduces the complexity of maneuvering the respective guidewires.

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Anesthesiology (AREA)
  • Hematology (AREA)
  • Pulmonology (AREA)
  • Cardiology (AREA)
  • Physics & Mathematics (AREA)
  • Plasma & Fusion (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Otolaryngology (AREA)
  • Biophysics (AREA)
  • Medical Informatics (AREA)
  • Molecular Biology (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • Electrotherapy Devices (AREA)

Abstract

L'invention concerne un fil-guide (20) d'électrophysiologie comprenant une âme (22) de forme allongée et un mécanisme (24) spiralé biocompatible disposé en hélice autour de l'âme (22) de manière à définir une pluralité d'enroulements. Le mécanisme (24) spiralé est constitué d'un conducteur (A, B, C, D) au moins recouvert extérieurement d'une couche d'isolation. L'isolation est conçue pour être sélectivement retirée de manière à exposer une partie dudit conducteur (A, B, C, D) pour définir une électrode (#1, #2, #3, #4) au moins. Le fil-guide (20) est fabriqué en plusieurs étapes, lesquelles consistent à sélectionner une âme (22) moulable de forme allongée; à enrouler un conducteur (A, B, C, D) isolé au moins en hélice autour de l'âme (22) de manière à définir une pluralité d'enroulements isolés; et à retirer une partie de l'isolation sur l'un des enroulements au moins de manière à définir une électrode (#1, #2, #3, #4) au moins.
PCT/US2000/010982 1999-04-20 2000-04-20 Fil-guide d'electrophysiologie et procede de fabrication correspondant WO2000062851A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US29519999A 1999-04-20 1999-04-20
US295,199 1999-04-20

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WO2000062851A1 true WO2000062851A1 (fr) 2000-10-26

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Cited By (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002085442A1 (fr) * 2001-04-19 2002-10-31 Radi Medical Systems Ab Systeme combine de detecteur pression-volume et de fil-guide combines
KR100375761B1 (ko) * 2000-12-29 2003-03-15 주식회사 샤인 발열 가이드와이어
WO2008008428A1 (fr) * 2006-07-12 2008-01-17 Kensey Nash Corporation Système de cathéter de remplacement de fil-guide
WO2010063078A1 (fr) * 2008-12-05 2010-06-10 Cathrx Ltd Cathéter d'irrigation et procédé pour sa fabrication
JP2012183125A (ja) * 2011-03-03 2012-09-27 Asahi Intecc Co Ltd ロープ、及び該ロープを用いた回収機構用螺旋状ロープ
CN104095626A (zh) * 2013-04-11 2014-10-15 韦伯斯特生物官能(以色列)有限公司 高密度电极结构
EP2763580A4 (fr) * 2011-10-04 2015-07-08 Lake Region Mfg Inc D B A Lake Region Medical Fil de guidage multiconducteur ou multipolaire
US9675265B2 (en) 2006-12-13 2017-06-13 Koninklijke Philips N.V. Feeding tube
US10575743B2 (en) 2013-04-11 2020-03-03 Biosense Webster (Israel) Ltd. High electrode density basket catheter
CN113693717A (zh) * 2021-08-30 2021-11-26 上海安通医疗科技有限公司 一种可用于桡动脉入路的射频消融导管
EP3810005A4 (fr) * 2018-06-20 2022-04-06 Magneto Thrombectomy Solutions Ltd. Divers dispositifs de thrombectomie
US11311332B2 (en) 2011-08-23 2022-04-26 Magneto Thrombectomy Solutions Ltd. Thrombectomy devices
US11660105B2 (en) 2017-11-23 2023-05-30 Magneto Thrombectomy Solutions Ltd. Tubular thrombectomy devices
US12029475B2 (en) 2017-03-22 2024-07-09 Magneto Thrombectomy Solutions Ltd. Thrombectomy using both electrostatic and suction forces

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US4922294A (en) 1987-11-05 1990-05-01 Minolta Camera Kabushiki Kaisha Image forming apparatus
EP0617916A1 (fr) * 1993-04-01 1994-10-05 Terumo Kabushiki Kaisha Capteur à plusieurs électrodes et procédé de fabrication
WO1995010318A1 (fr) * 1993-10-14 1995-04-20 Ep Technologies, Inc. Electrodes permettant de creer des lesions d'une configuration particuliere
EP0659388A1 (fr) * 1993-12-20 1995-06-28 Terumo Kabushiki Kaisha Système pour carthographie et ablation d'endocarde
US5465732A (en) 1992-03-31 1995-11-14 Boston Scientific Corporation Fluoroscopically viewable multifilar calibrated guidewire and method of measuring occlusions with calibrated guidewires
US5482037A (en) 1993-01-18 1996-01-09 X-Trode S.R.L. Electrode catheter for mapping and operating on cardiac cavities
EP0732080A1 (fr) * 1995-03-17 1996-09-18 Daig Corporation Cathéter d'ablation

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4922294A (en) 1987-11-05 1990-05-01 Minolta Camera Kabushiki Kaisha Image forming apparatus
US5465732A (en) 1992-03-31 1995-11-14 Boston Scientific Corporation Fluoroscopically viewable multifilar calibrated guidewire and method of measuring occlusions with calibrated guidewires
US5482037A (en) 1993-01-18 1996-01-09 X-Trode S.R.L. Electrode catheter for mapping and operating on cardiac cavities
EP0617916A1 (fr) * 1993-04-01 1994-10-05 Terumo Kabushiki Kaisha Capteur à plusieurs électrodes et procédé de fabrication
WO1995010318A1 (fr) * 1993-10-14 1995-04-20 Ep Technologies, Inc. Electrodes permettant de creer des lesions d'une configuration particuliere
EP0659388A1 (fr) * 1993-12-20 1995-06-28 Terumo Kabushiki Kaisha Système pour carthographie et ablation d'endocarde
EP0732080A1 (fr) * 1995-03-17 1996-09-18 Daig Corporation Cathéter d'ablation

Cited By (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100375761B1 (ko) * 2000-12-29 2003-03-15 주식회사 샤인 발열 가이드와이어
WO2002085442A1 (fr) * 2001-04-19 2002-10-31 Radi Medical Systems Ab Systeme combine de detecteur pression-volume et de fil-guide combines
US6926674B2 (en) 2001-04-19 2005-08-09 Radi Medical Systems Ab Combined pressure-volume sensor and guide wire assembly
WO2008008428A1 (fr) * 2006-07-12 2008-01-17 Kensey Nash Corporation Système de cathéter de remplacement de fil-guide
US8911406B2 (en) 2006-07-12 2014-12-16 Kensey Nash Corporation Guide wire exchange catheter system
US9675265B2 (en) 2006-12-13 2017-06-13 Koninklijke Philips N.V. Feeding tube
WO2010063078A1 (fr) * 2008-12-05 2010-06-10 Cathrx Ltd Cathéter d'irrigation et procédé pour sa fabrication
AU2009322090B2 (en) * 2008-12-05 2015-02-12 Cathrx Ltd An irrigation catheter and a method of fabricating
US9227036B2 (en) 2008-12-05 2016-01-05 Cathrx Ltd Irrigation catheter and a method of fabricating
JP2012183125A (ja) * 2011-03-03 2012-09-27 Asahi Intecc Co Ltd ロープ、及び該ロープを用いた回収機構用螺旋状ロープ
US11311332B2 (en) 2011-08-23 2022-04-26 Magneto Thrombectomy Solutions Ltd. Thrombectomy devices
US9446219B2 (en) 2011-10-04 2016-09-20 Lake Region Manufacturing, Inc. Multiconductor or multipolar guidewire
EP2763580A4 (fr) * 2011-10-04 2015-07-08 Lake Region Mfg Inc D B A Lake Region Medical Fil de guidage multiconducteur ou multipolaire
CN104095626A (zh) * 2013-04-11 2014-10-15 韦伯斯特生物官能(以色列)有限公司 高密度电极结构
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