WO2000041761A1 - Dispositif medical gonflable muni d'elements d'injection destines a l'injection dans des zones localisees - Google Patents

Dispositif medical gonflable muni d'elements d'injection destines a l'injection dans des zones localisees Download PDF

Info

Publication number
WO2000041761A1
WO2000041761A1 PCT/US1999/025751 US9925751W WO0041761A1 WO 2000041761 A1 WO2000041761 A1 WO 2000041761A1 US 9925751 W US9925751 W US 9925751W WO 0041761 A1 WO0041761 A1 WO 0041761A1
Authority
WO
WIPO (PCT)
Prior art keywords
fluid
vessel
wall
dispensers
balloon
Prior art date
Application number
PCT/US1999/025751
Other languages
English (en)
Inventor
Dennis M. Vigil
Robert E. Reiss
Peter Barath
Original Assignee
Interventional Technologies, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US09/232,392 external-priority patent/US6210392B1/en
Priority claimed from US09/232,156 external-priority patent/US6102904A/en
Application filed by Interventional Technologies, Inc. filed Critical Interventional Technologies, Inc.
Priority to CA002359503A priority Critical patent/CA2359503C/fr
Priority to IL14416499A priority patent/IL144164A0/xx
Priority to AU13376/00A priority patent/AU764112B2/en
Priority to EP99956855A priority patent/EP1165176A4/fr
Priority to KR1020017008984A priority patent/KR20020000860A/ko
Priority to JP2000593369A priority patent/JP2003532439A/ja
Publication of WO2000041761A1 publication Critical patent/WO2000041761A1/fr
Priority to TW090121975A priority patent/TW504393B/zh
Priority to HK03100998.9A priority patent/HK1048958A1/zh

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M29/00—Dilators with or without means for introducing media, e.g. remedies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/10—Balloon catheters
    • A61M25/104—Balloon catheters used for angioplasty
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/10—Balloon catheters
    • A61M25/1002—Balloon catheters characterised by balloon shape
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/0043—Catheters; Hollow probes characterised by structural features
    • A61M2025/0057—Catheters delivering medicament other than through a conventional lumen, e.g. porous walls or hydrogel coatings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/10—Balloon catheters
    • A61M2025/1043—Balloon catheters with special features or adapted for special applications
    • A61M2025/105—Balloon catheters with special features or adapted for special applications having a balloon suitable for drug delivery, e.g. by using holes for delivery, drug coating or membranes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00—Catheters; Hollow probes
    • A61M25/10—Balloon catheters
    • A61M2025/1043—Balloon catheters with special features or adapted for special applications
    • A61M2025/1086—Balloon catheters with special features or adapted for special applications having a special balloon surface topography, e.g. pores, protuberances, spikes or grooves

Definitions

  • the dispenser 20 penetrates the endothelium layer 35a, the basement membrane layer 35b, and the lamina layer 35c and precisely delivers the fluid 13 to the media layer 35d, i.e. the target layer in this example.
  • a shorter dispenser 20 could be utilized to deliver the fluid 13 to the lamina layer 35c.
  • the device 10 can be used to simultaneously dilate the vessel 11.
  • Suitable fluids can include anti-proliferative agents such as methotrexate, prednisone, adriamycin, mitomycinc, protein synthesis inhibitors, toxin fragments such as pseudomonas, exotoxin (PE) or Ricin A (RA) Toxin, and radioactive isotopes 112 such as 111 lndium, 90 Yttrium, 67 Gallium, 99m Tc (Technetium 99), 205 Thallium, and 32 P (Phosphorous 32) radiopharmaceutical. It is believed that the present device provided is uniquely suited to safely deliver dangerous fluids 13 into the vessel wall 11 while minimizing the amount of fluid 13 which is washed away into the blood stream.
  • anti-proliferative agents such as methotrexate, prednisone, adriamycin, mitomycinc, protein synthesis inhibitors, toxin fragments such as pseudomonas, exotoxin (PE) or Ricin A (RA

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Child & Adolescent Psychology (AREA)
  • Pulmonology (AREA)
  • Vascular Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
  • Media Introduction/Drainage Providing Device (AREA)
  • External Artificial Organs (AREA)

Abstract

Cette invention concerne un procédé et un dispositif permettant l'injection d'un fluide destiné au traitement des parois vasculaires. Une première version du dispositif comprend un ballonnet gonflable monté sur une sonde et une pluralité d'éléments d'injection, dirigés vers l'extérieur du ballonnet et se déplaçant avec lui. Au moins un canal fluidique permet la connexion fluidique entre chacun des éléments d'injection et une source fluidique. Lors de l'utilisation du dispositif, le ballonnet est tout d'abord placé dans un vaisseau à proximité de la zone à traiter. Le ballonnet est ensuite gonflé de sorte qu'il s'encastre entre les parois du vaisseau. Le fluide provenant de la source fluidique est alors introduit dans le canal fluidique et atteint les zones à traiter en passant par les éléments d'injection. Une seconde version du dispositif comprend une pluralité de tubes flexibles montés entre une sonde multilumière et une rondelle. Un fil double effet est connecté à la rondelle et passe dans la lumière de la sonde multilumière.
PCT/US1999/025751 1999-01-15 1999-12-06 Dispositif medical gonflable muni d'elements d'injection destines a l'injection dans des zones localisees WO2000041761A1 (fr)

Priority Applications (8)

Application Number Priority Date Filing Date Title
CA002359503A CA2359503C (fr) 1999-01-15 1999-12-06 Dispositif medical gonflable muni d'elements d'injection destines a l'injection dans des zones localisees
IL14416499A IL144164A0 (en) 1999-01-15 1999-12-06 Inflatable medical device maintaining injectors for delivery to a localized region
AU13376/00A AU764112B2 (en) 1999-01-15 1999-12-06 Inflatable medical device maintaining injectors for delivery to a localized region
EP99956855A EP1165176A4 (fr) 1999-01-15 1999-12-06 Dispositif medical gonflable muni d'elements d'injection destines a l'injection dans des zones localisees
KR1020017008984A KR20020000860A (ko) 1999-01-15 1999-12-06 국소부위로 전달하기 위한 주입기를 장착한 팽창가능한의학 장치
JP2000593369A JP2003532439A (ja) 1999-01-15 1999-12-06 局所領域に流体を送るように注射器を保持する膨張可能な医療装置
TW090121975A TW504393B (en) 1999-12-06 2001-09-05 Device and method for treating a wall of a blood vessel
HK03100998.9A HK1048958A1 (zh) 1999-01-15 2003-02-11 保持住向定點區域送藥的注射頭所用的可充脹醫療裝置

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US09/232,392 US6210392B1 (en) 1999-01-15 1999-01-15 Method for treating a wall of a blood vessel
US09/232,156 1999-01-15
US09/232,156 US6102904A (en) 1995-07-10 1999-01-15 Device for injecting fluid into a wall of a blood vessel
US09/232,392 1999-01-15

Publications (1)

Publication Number Publication Date
WO2000041761A1 true WO2000041761A1 (fr) 2000-07-20

Family

ID=26925730

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/US1999/025751 WO2000041761A1 (fr) 1999-01-15 1999-12-06 Dispositif medical gonflable muni d'elements d'injection destines a l'injection dans des zones localisees

Country Status (9)

Country Link
EP (1) EP1165176A4 (fr)
JP (1) JP2003532439A (fr)
KR (1) KR20020000860A (fr)
CN (1) CN1383385A (fr)
AU (1) AU764112B2 (fr)
CA (1) CA2359503C (fr)
HK (1) HK1048958A1 (fr)
IL (1) IL144164A0 (fr)
WO (1) WO2000041761A1 (fr)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1230944A3 (fr) * 2001-02-07 2002-08-21 Interventional Technologies Inc Appareil d'administration de médicament dans les parois artérielles pour prévenir la resténose
JP2004504111A (ja) * 2000-07-24 2004-02-12 グレイゼル、ジェフリー 拡張術およびステント術用の補剛バルーン・カテーテル
EP1604704A1 (fr) * 2004-06-08 2005-12-14 Cordis Corporation Dispositif d'administration de médicaments au moyen de microprojections
EP1764128A1 (fr) * 2005-09-20 2007-03-21 Sorin Biomedica Cardio S.R.L. Dispositif pour la thérapie cellulaire
EP2056918A2 (fr) * 2006-08-29 2009-05-13 Tissue Genesis, Inc. Cathéter servant à administrer des cellules
US9051629B2 (en) 2010-11-25 2015-06-09 Commissariat A L'energie Atomique Et Aux Energies Alternatives Process for separating americium from other metallic elements present in an acidic aqueous or organic phase
US9616199B2 (en) 2009-12-31 2017-04-11 St. Jude Medical, Atrial Fibrillation Division, Inc. Irrigated catheter employing multi-lumenal irrigation tubing

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20070088335A1 (en) * 2001-10-24 2007-04-19 Med-El Elektromedizinische Geraete Gmbh Implantable neuro-stimulation electrode with fluid reservoir
CN101277733B (zh) * 2005-06-21 2012-07-11 梅德拉股份有限公司 医用流体注射和充胀系统
CN101045175B (zh) * 2006-03-29 2012-07-04 微创医疗器械(上海)有限公司 双层球囊导管
CN100550084C (zh) * 2007-07-21 2009-10-14 东经控股集团有限公司 在具有狭窄通道的物品上设置细小物的方法及其专用装置
CA2860593A1 (fr) * 2012-01-23 2013-08-01 Shifamed Holdings, Llc Rupture de tissu intravasculaire
JP2015097547A (ja) * 2012-03-09 2015-05-28 テルモ株式会社 バルーンカテーテル
JP2015163088A (ja) * 2012-06-26 2015-09-10 テルモ株式会社 医療器具
CN103463726B (zh) * 2013-08-20 2015-05-27 深圳市信立泰生物医疗工程有限公司 一种球囊扩张导管
CN104436421B (zh) * 2014-11-28 2017-12-01 刘宗军 一种可灌注药物球囊

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5242397A (en) * 1989-06-20 1993-09-07 Cedars-Sinai Medical Center Catheter device and method of use for intramural delivery of protein kinase C and tyrosine protein kinase inhibitors to prevent restenosis after balloon angioplasty
US5681281A (en) * 1995-07-10 1997-10-28 Interventional Technologies, Inc. Catheter with fluid medication injectors
US5713863A (en) * 1996-01-11 1998-02-03 Interventional Technologies Inc. Catheter with fluid medication injectors

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994023787A1 (fr) * 1993-04-22 1994-10-27 Rammler David H Catheter a ballon de prelevement

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5242397A (en) * 1989-06-20 1993-09-07 Cedars-Sinai Medical Center Catheter device and method of use for intramural delivery of protein kinase C and tyrosine protein kinase inhibitors to prevent restenosis after balloon angioplasty
US5681281A (en) * 1995-07-10 1997-10-28 Interventional Technologies, Inc. Catheter with fluid medication injectors
US5746716A (en) * 1995-07-10 1998-05-05 Interventional Technologies Inc. Catheter for injecting fluid medication into an arterial wall
US5713863A (en) * 1996-01-11 1998-02-03 Interventional Technologies Inc. Catheter with fluid medication injectors

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
See also references of EP1165176A4 *

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6695830B2 (en) 1999-01-15 2004-02-24 Scimed Life Systems, Inc. Method for delivering medication into an arterial wall for prevention of restenosis
US8066690B2 (en) 1999-01-15 2011-11-29 Boston Scientific Scimed, Inc. Method for delivering medication into an arterial wall for prevention of restenosis
JP2004504111A (ja) * 2000-07-24 2004-02-12 グレイゼル、ジェフリー 拡張術およびステント術用の補剛バルーン・カテーテル
EP1230944A3 (fr) * 2001-02-07 2002-08-21 Interventional Technologies Inc Appareil d'administration de médicament dans les parois artérielles pour prévenir la resténose
EP1604704A1 (fr) * 2004-06-08 2005-12-14 Cordis Corporation Dispositif d'administration de médicaments au moyen de microprojections
EP1764128A1 (fr) * 2005-09-20 2007-03-21 Sorin Biomedica Cardio S.R.L. Dispositif pour la thérapie cellulaire
EP2056918A2 (fr) * 2006-08-29 2009-05-13 Tissue Genesis, Inc. Cathéter servant à administrer des cellules
EP2056918A4 (fr) * 2006-08-29 2014-01-08 Tissue Genesis Inc Cathéter servant à administrer des cellules
US9616199B2 (en) 2009-12-31 2017-04-11 St. Jude Medical, Atrial Fibrillation Division, Inc. Irrigated catheter employing multi-lumenal irrigation tubing
US9051629B2 (en) 2010-11-25 2015-06-09 Commissariat A L'energie Atomique Et Aux Energies Alternatives Process for separating americium from other metallic elements present in an acidic aqueous or organic phase

Also Published As

Publication number Publication date
CN1383385A (zh) 2002-12-04
JP2003532439A (ja) 2003-11-05
KR20020000860A (ko) 2002-01-05
AU1337600A (en) 2000-08-01
IL144164A0 (en) 2002-05-23
EP1165176A1 (fr) 2002-01-02
CA2359503C (fr) 2008-05-13
EP1165176A4 (fr) 2006-12-13
AU764112B2 (en) 2003-08-07
HK1048958A1 (zh) 2003-04-25
CA2359503A1 (fr) 2000-07-20

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