CA2359503C - Dispositif medical gonflable muni d'elements d'injection destines a l'injection dans des zones localisees - Google Patents
Dispositif medical gonflable muni d'elements d'injection destines a l'injection dans des zones localisees Download PDFInfo
- Publication number
- CA2359503C CA2359503C CA002359503A CA2359503A CA2359503C CA 2359503 C CA2359503 C CA 2359503C CA 002359503 A CA002359503 A CA 002359503A CA 2359503 A CA2359503 A CA 2359503A CA 2359503 C CA2359503 C CA 2359503C
- Authority
- CA
- Canada
- Prior art keywords
- fluid
- vessel
- wall
- dispensers
- dispenser
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 239000012530 fluid Substances 0.000 claims abstract description 226
- 238000004891 communication Methods 0.000 claims abstract description 11
- 239000002244 precipitate Substances 0.000 claims description 17
- 239000011230 binding agent Substances 0.000 claims description 14
- 230000002285 radioactive effect Effects 0.000 claims description 14
- 108090000623 proteins and genes Proteins 0.000 claims description 10
- 230000008961 swelling Effects 0.000 claims description 10
- 210000004204 blood vessel Anatomy 0.000 claims description 7
- 239000003446 ligand Substances 0.000 claims description 7
- 230000035755 proliferation Effects 0.000 claims description 6
- 102000008186 Collagen Human genes 0.000 claims description 5
- 108010035532 Collagen Proteins 0.000 claims description 5
- 229920001436 collagen Polymers 0.000 claims description 5
- 230000008467 tissue growth Effects 0.000 claims description 5
- 238000004519 manufacturing process Methods 0.000 claims description 4
- GKLVYJBZJHMRIY-OUBTZVSYSA-N Technetium-99 Chemical compound [99Tc] GKLVYJBZJHMRIY-OUBTZVSYSA-N 0.000 claims description 3
- 238000013459 approach Methods 0.000 claims description 3
- ZBKIUFWVEIBQRT-UHFFFAOYSA-N gold(1+) Chemical compound [Au+] ZBKIUFWVEIBQRT-UHFFFAOYSA-N 0.000 claims description 3
- BHEPBYXIRTUNPN-UHFFFAOYSA-N hydridophosphorus(.) (triplet) Chemical compound [PH] BHEPBYXIRTUNPN-UHFFFAOYSA-N 0.000 claims description 3
- 229940121896 radiopharmaceutical Drugs 0.000 claims description 3
- 239000012217 radiopharmaceutical Substances 0.000 claims description 3
- 230000002799 radiopharmaceutical effect Effects 0.000 claims description 3
- 102000004169 proteins and genes Human genes 0.000 claims description 2
- 238000000034 method Methods 0.000 abstract description 18
- 208000031481 Pathologic Constriction Diseases 0.000 description 15
- 208000037804 stenosis Diseases 0.000 description 15
- 230000036262 stenosis Effects 0.000 description 15
- 239000008280 blood Substances 0.000 description 14
- 210000004369 blood Anatomy 0.000 description 14
- 239000012716 precipitator Substances 0.000 description 12
- 210000004027 cell Anatomy 0.000 description 9
- 206010042674 Swelling Diseases 0.000 description 8
- 208000037803 restenosis Diseases 0.000 description 8
- 230000001028 anti-proliverative effect Effects 0.000 description 6
- 239000003795 chemical substances by application Substances 0.000 description 6
- 230000007246 mechanism Effects 0.000 description 6
- 238000002399 angioplasty Methods 0.000 description 5
- 210000001367 artery Anatomy 0.000 description 5
- -1 mitomycinc Substances 0.000 description 5
- 239000000203 mixture Substances 0.000 description 5
- 230000000149 penetrating effect Effects 0.000 description 5
- 210000000329 smooth muscle myocyte Anatomy 0.000 description 5
- 108020004414 DNA Proteins 0.000 description 4
- AOJJSUZBOXZQNB-TZSSRYMLSA-N Doxorubicin Chemical compound O([C@H]1C[C@@](O)(CC=2C(O)=C3C(=O)C=4C=CC=C(C=4C(=O)C3=C(O)C=21)OC)C(=O)CO)[C@H]1C[C@H](N)[C@H](O)[C@H](C)O1 AOJJSUZBOXZQNB-TZSSRYMLSA-N 0.000 description 4
- PXHVJJICTQNCMI-UHFFFAOYSA-N Nickel Chemical compound [Ni] PXHVJJICTQNCMI-UHFFFAOYSA-N 0.000 description 4
- 210000003038 endothelium Anatomy 0.000 description 4
- 238000009472 formulation Methods 0.000 description 4
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- 210000002469 basement membrane Anatomy 0.000 description 3
- 201000010099 disease Diseases 0.000 description 3
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- 238000001415 gene therapy Methods 0.000 description 3
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- 238000000926 separation method Methods 0.000 description 3
- 230000008733 trauma Effects 0.000 description 3
- OTLLEIBWKHEHGU-UHFFFAOYSA-N 2-[5-[[5-(6-aminopurin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy]-3,4-dihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy-3,5-dihydroxy-4-phosphonooxyhexanedioic acid Chemical compound C1=NC=2C(N)=NC=NC=2N1C(C(C1O)O)OC1COC1C(CO)OC(OC(C(O)C(OP(O)(O)=O)C(O)C(O)=O)C(O)=O)C(O)C1O OTLLEIBWKHEHGU-UHFFFAOYSA-N 0.000 description 2
- FBOZXECLQNJBKD-ZDUSSCGKSA-N L-methotrexate Chemical compound C=1N=C2N=C(N)N=C(N)C2=NC=1CN(C)C1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 FBOZXECLQNJBKD-ZDUSSCGKSA-N 0.000 description 2
- 108091008606 PDGF receptors Proteins 0.000 description 2
- 102000011653 Platelet-Derived Growth Factor Receptors Human genes 0.000 description 2
- 229940123573 Protein synthesis inhibitor Drugs 0.000 description 2
- 241000589516 Pseudomonas Species 0.000 description 2
- 108010039491 Ricin Proteins 0.000 description 2
- 102000003790 Thrombin receptors Human genes 0.000 description 2
- 108090000166 Thrombin receptors Proteins 0.000 description 2
- 241000700605 Viruses Species 0.000 description 2
- VWQVUPCCIRVNHF-OUBTZVSYSA-N Yttrium-90 Chemical compound [90Y] VWQVUPCCIRVNHF-OUBTZVSYSA-N 0.000 description 2
- 230000009471 action Effects 0.000 description 2
- 239000000853 adhesive Substances 0.000 description 2
- 230000001070 adhesive effect Effects 0.000 description 2
- 229940009456 adriamycin Drugs 0.000 description 2
- 229920002988 biodegradable polymer Polymers 0.000 description 2
- 239000004621 biodegradable polymer Substances 0.000 description 2
- 238000010276 construction Methods 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 231100000776 exotoxin Toxicity 0.000 description 2
- 239000002095 exotoxin Substances 0.000 description 2
- 239000012634 fragment Substances 0.000 description 2
- 230000012010 growth Effects 0.000 description 2
- 229910052738 indium Inorganic materials 0.000 description 2
- APFVFJFRJDLVQX-UHFFFAOYSA-N indium atom Chemical compound [In] APFVFJFRJDLVQX-UHFFFAOYSA-N 0.000 description 2
- 102000006495 integrins Human genes 0.000 description 2
- 108010044426 integrins Proteins 0.000 description 2
- 238000002955 isolation Methods 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- 229960000485 methotrexate Drugs 0.000 description 2
- 229910052759 nickel Inorganic materials 0.000 description 2
- 210000000056 organ Anatomy 0.000 description 2
- 230000001575 pathological effect Effects 0.000 description 2
- 230000035515 penetration Effects 0.000 description 2
- 229920000139 polyethylene terephthalate Polymers 0.000 description 2
- 239000005020 polyethylene terephthalate Substances 0.000 description 2
- 239000011148 porous material Substances 0.000 description 2
- XOFYZVNMUHMLCC-ZPOLXVRWSA-N prednisone Chemical compound O=C1C=C[C@]2(C)[C@H]3C(=O)C[C@](C)([C@@](CC4)(O)C(=O)CO)[C@@H]4[C@@H]3CCC2=C1 XOFYZVNMUHMLCC-ZPOLXVRWSA-N 0.000 description 2
- 229960004618 prednisone Drugs 0.000 description 2
- 239000000007 protein synthesis inhibitor Substances 0.000 description 2
- 230000001177 retroviral effect Effects 0.000 description 2
- 241000701161 unidentified adenovirus Species 0.000 description 2
- JCZPMGDSEAFWDY-MBMOQRBOSA-N (2s,3s,4r,5r)-2,3,4,5,6-pentahydroxyhexanamide Chemical compound NC(=O)[C@@H](O)[C@@H](O)[C@H](O)[C@H](O)CO JCZPMGDSEAFWDY-MBMOQRBOSA-N 0.000 description 1
- 201000004569 Blindness Diseases 0.000 description 1
- HTTJABKRGRZYRN-UHFFFAOYSA-N Heparin Chemical compound OC1C(NC(=O)C)C(O)OC(COS(O)(=O)=O)C1OC1C(OS(O)(=O)=O)C(O)C(OC2C(C(OS(O)(=O)=O)C(OC3C(C(O)C(O)C(O3)C(O)=O)OS(O)(=O)=O)C(CO)O2)NS(O)(=O)=O)C(C(O)=O)O1 HTTJABKRGRZYRN-UHFFFAOYSA-N 0.000 description 1
- 108091061960 Naked DNA Proteins 0.000 description 1
- 231100000987 absorbed dose Toxicity 0.000 description 1
- 210000000748 cardiovascular system Anatomy 0.000 description 1
- 230000010261 cell growth Effects 0.000 description 1
- 230000001413 cellular effect Effects 0.000 description 1
- 210000002808 connective tissue Anatomy 0.000 description 1
- 238000013461 design Methods 0.000 description 1
- 230000010339 dilation Effects 0.000 description 1
- 238000006073 displacement reaction Methods 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 210000002889 endothelial cell Anatomy 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 239000010931 gold Substances 0.000 description 1
- 230000009931 harmful effect Effects 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 229960002897 heparin Drugs 0.000 description 1
- 229920000669 heparin Polymers 0.000 description 1
- 238000001802 infusion Methods 0.000 description 1
- 238000003780 insertion Methods 0.000 description 1
- 230000037431 insertion Effects 0.000 description 1
- 239000002502 liposome Substances 0.000 description 1
- 230000037361 pathway Effects 0.000 description 1
- 238000005086 pumping Methods 0.000 description 1
- 238000004080 punching Methods 0.000 description 1
- 239000001397 quillaja saponaria molina bark Substances 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
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- 230000000717 retained effect Effects 0.000 description 1
- 229930182490 saponin Natural products 0.000 description 1
- 150000007949 saponins Chemical class 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 231100000167 toxic agent Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 239000003440 toxic substance Substances 0.000 description 1
- 239000013603 viral vector Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M29/00—Dilators with or without means for introducing media, e.g. remedies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/10—Balloon catheters
- A61M25/104—Balloon catheters used for angioplasty
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/10—Balloon catheters
- A61M25/1002—Balloon catheters characterised by balloon shape
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/0043—Catheters; Hollow probes characterised by structural features
- A61M2025/0057—Catheters delivering medicament other than through a conventional lumen, e.g. porous walls or hydrogel coatings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/10—Balloon catheters
- A61M2025/1043—Balloon catheters with special features or adapted for special applications
- A61M2025/105—Balloon catheters with special features or adapted for special applications having a balloon suitable for drug delivery, e.g. by using holes for delivery, drug coating or membranes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M25/00—Catheters; Hollow probes
- A61M25/10—Balloon catheters
- A61M2025/1043—Balloon catheters with special features or adapted for special applications
- A61M2025/1086—Balloon catheters with special features or adapted for special applications having a special balloon surface topography, e.g. pores, protuberances, spikes or grooves
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Hematology (AREA)
- General Health & Medical Sciences (AREA)
- Biophysics (AREA)
- Child & Adolescent Psychology (AREA)
- Pulmonology (AREA)
- Vascular Medicine (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Media Introduction/Drainage Providing Device (AREA)
- External Artificial Organs (AREA)
- Surgical Instruments (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/232,156 | 1999-01-15 | ||
| US09/232,392 US6210392B1 (en) | 1999-01-15 | 1999-01-15 | Method for treating a wall of a blood vessel |
| US09/232,156 US6102904A (en) | 1995-07-10 | 1999-01-15 | Device for injecting fluid into a wall of a blood vessel |
| US09/232,392 | 1999-01-15 | ||
| PCT/US1999/025751 WO2000041761A1 (fr) | 1999-01-15 | 1999-12-06 | Dispositif medical gonflable muni d'elements d'injection destines a l'injection dans des zones localisees |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CA2359503A1 CA2359503A1 (fr) | 2000-07-20 |
| CA2359503C true CA2359503C (fr) | 2008-05-13 |
Family
ID=26925730
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA002359503A Expired - Fee Related CA2359503C (fr) | 1999-01-15 | 1999-12-06 | Dispositif medical gonflable muni d'elements d'injection destines a l'injection dans des zones localisees |
Country Status (9)
| Country | Link |
|---|---|
| EP (1) | EP1165176A4 (fr) |
| JP (1) | JP2003532439A (fr) |
| KR (1) | KR20020000860A (fr) |
| CN (1) | CN1383385A (fr) |
| AU (1) | AU764112B2 (fr) |
| CA (1) | CA2359503C (fr) |
| HK (1) | HK1048958A1 (fr) |
| IL (1) | IL144164A0 (fr) |
| WO (1) | WO2000041761A1 (fr) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6695830B2 (en) | 1999-01-15 | 2004-02-24 | Scimed Life Systems, Inc. | Method for delivering medication into an arterial wall for prevention of restenosis |
| ES2365208T3 (es) * | 2000-07-24 | 2011-09-26 | Jeffrey Grayzel | Catéter con globo rigidizado para dilatación e implantación de prótesis endovasculares. |
| US20070088335A1 (en) * | 2001-10-24 | 2007-04-19 | Med-El Elektromedizinische Geraete Gmbh | Implantable neuro-stimulation electrode with fluid reservoir |
| US20050273049A1 (en) * | 2004-06-08 | 2005-12-08 | Peter Krulevitch | Drug delivery device using microprojections |
| EP1893279A4 (fr) * | 2005-06-21 | 2010-12-29 | Medrad Inc | Systeme medical d'injection de fluide et de gonflage |
| ITTO20050650A1 (it) * | 2005-09-20 | 2007-03-21 | Sorin Biomedica Cardio Srl | Dispositivo per terapia cellulare |
| CN101045175B (zh) * | 2006-03-29 | 2012-07-04 | 微创医疗器械(上海)有限公司 | 双层球囊导管 |
| EP2056918B1 (fr) * | 2006-08-29 | 2017-08-23 | Tissue Genesis, Inc. | Cathéter servant à administrer des cellules |
| CN100550084C (zh) * | 2007-07-21 | 2009-10-14 | 东经控股集团有限公司 | 在具有狭窄通道的物品上设置细小物的方法及其专用装置 |
| US9616199B2 (en) * | 2009-12-31 | 2017-04-11 | St. Jude Medical, Atrial Fibrillation Division, Inc. | Irrigated catheter employing multi-lumenal irrigation tubing |
| FR2968014B1 (fr) | 2010-11-25 | 2012-12-28 | Commissariat Energie Atomique | Procede de separation de l'americium des autres elements metalliques presents dans une phase aqueuse acide ou organique et ses applications |
| CN104066463B (zh) * | 2012-01-23 | 2017-05-31 | 施菲姆德控股有限责任公司 | 血管内组织干扰 |
| JP2015097547A (ja) * | 2012-03-09 | 2015-05-28 | テルモ株式会社 | バルーンカテーテル |
| JP2015163088A (ja) * | 2012-06-26 | 2015-09-10 | テルモ株式会社 | 医療器具 |
| CN103463726B (zh) * | 2013-08-20 | 2015-05-27 | 深圳市信立泰生物医疗工程有限公司 | 一种球囊扩张导管 |
| CN104436421B (zh) * | 2014-11-28 | 2017-12-01 | 刘宗军 | 一种可灌注药物球囊 |
| CN113769242B (zh) * | 2020-05-20 | 2024-07-12 | 上海微创医疗器械（集团）有限公司 | 球囊导管 |
| KR102784415B1 (ko) | 2024-03-15 | 2025-03-19 | 조은비 | 라이다센서와 ai영상 분석 기술을 이용한 스마트 횡단보도의 우회전 위반 판독 방법 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5242397A (en) * | 1989-06-20 | 1993-09-07 | Cedars-Sinai Medical Center | Catheter device and method of use for intramural delivery of protein kinase C and tyrosine protein kinase inhibitors to prevent restenosis after balloon angioplasty |
| WO1994023787A1 (fr) * | 1993-04-22 | 1994-10-27 | Rammler David H | Catheter a ballon de prelevement |
| US5746716A (en) * | 1995-07-10 | 1998-05-05 | Interventional Technologies Inc. | Catheter for injecting fluid medication into an arterial wall |
| US5713863A (en) * | 1996-01-11 | 1998-02-03 | Interventional Technologies Inc. | Catheter with fluid medication injectors |
-
1999
- 1999-12-06 AU AU13376/00A patent/AU764112B2/en not_active Ceased
- 1999-12-06 KR KR1020017008984A patent/KR20020000860A/ko not_active Withdrawn
- 1999-12-06 HK HK03100998.9A patent/HK1048958A1/zh unknown
- 1999-12-06 EP EP99956855A patent/EP1165176A4/fr not_active Withdrawn
- 1999-12-06 WO PCT/US1999/025751 patent/WO2000041761A1/fr not_active Ceased
- 1999-12-06 JP JP2000593369A patent/JP2003532439A/ja not_active Withdrawn
- 1999-12-06 IL IL14416499A patent/IL144164A0/xx unknown
- 1999-12-06 CN CN99816495A patent/CN1383385A/zh active Pending
- 1999-12-06 CA CA002359503A patent/CA2359503C/fr not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| HK1048958A1 (zh) | 2003-04-25 |
| WO2000041761A1 (fr) | 2000-07-20 |
| CA2359503A1 (fr) | 2000-07-20 |
| JP2003532439A (ja) | 2003-11-05 |
| AU764112B2 (en) | 2003-08-07 |
| KR20020000860A (ko) | 2002-01-05 |
| IL144164A0 (en) | 2002-05-23 |
| EP1165176A1 (fr) | 2002-01-02 |
| EP1165176A4 (fr) | 2006-12-13 |
| AU1337600A (en) | 2000-08-01 |
| CN1383385A (zh) | 2002-12-04 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| US6210392B1 (en) | Method for treating a wall of a blood vessel | |
| US6102904A (en) | Device for injecting fluid into a wall of a blood vessel | |
| US8066690B2 (en) | Method for delivering medication into an arterial wall for prevention of restenosis | |
| CA2359503C (fr) | Dispositif medical gonflable muni d'elements d'injection destines a l'injection dans des zones localisees | |
| AU738205B2 (en) | Device for injecting fluid into a wall of a blood vessel | |
| US7338468B2 (en) | Catheter for endoluminal delivery of therapeutic agents that minimizes loss of therapeutic | |
| AU704433B2 (en) | Catheter for injecting fluid medication into an arterial wall | |
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| JP4436761B2 (ja) | 薬剤放出用拡張性ポーションを備えた装置 | |
| US6547767B1 (en) | Syringe assembly for a catheter | |
| AU2005202037A1 (en) | Drug delivery device using microprojections | |
| JPH11506633A (ja) | 遠位分配マニホールドを有する注入スリーブカテーテル | |
| TW504393B (en) | Device and method for treating a wall of a blood vessel | |
| EP1051215A1 (fr) | Dispositif permettant d'injecter un fluide dans la paroi d'un vaisseau sanguin | |
| WO2000041763A9 (fr) | Appareil et procede d'administration localisee d'un medicament dans un tissu |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| EEER | Examination request | ||
| MKLA | Lapsed |
Effective date: 20121206 |