WO2000028844A1 - Systeme permettant de preparer un aerosol inhalable - Google Patents

Systeme permettant de preparer un aerosol inhalable Download PDF

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Publication number
WO2000028844A1
WO2000028844A1 PCT/EP1999/008429 EP9908429W WO0028844A1 WO 2000028844 A1 WO2000028844 A1 WO 2000028844A1 EP 9908429 W EP9908429 W EP 9908429W WO 0028844 A1 WO0028844 A1 WO 0028844A1
Authority
WO
WIPO (PCT)
Prior art keywords
substrate portions
substrate
aerosol
mouthpiece
portions
Prior art date
Application number
PCT/EP1999/008429
Other languages
German (de)
English (en)
Inventor
Thomas Pienemann
Original Assignee
H.F. & Ph.F.Reemtsma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by H.F. & Ph.F.Reemtsma Gmbh filed Critical H.F. & Ph.F.Reemtsma Gmbh
Priority to AU15510/00A priority Critical patent/AU1551000A/en
Priority to EP99957990A priority patent/EP1128742A1/fr
Publication of WO2000028844A1 publication Critical patent/WO2000028844A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24F—SMOKERS' REQUISITES; MATCH BOXES; SIMULATED SMOKING DEVICES
    • A24F40/00—Electrically operated smoking devices; Component parts thereof; Manufacture thereof; Maintenance or testing thereof; Charging means specially adapted therefor
    • A24F40/30—Devices using two or more structurally separated inhalable precursors, e.g. using two liquid precursors in two cartridges
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A61M15/0046—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier
    • A61M15/0048—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier the dosages being arranged in a plane, e.g. on diskettes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/0045—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters
    • A61M15/0046—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier
    • A61M15/0051—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using multiple prepacked dosages on a same carrier, e.g. blisters characterized by the type of carrier the dosages being arranged on a tape, e.g. strips
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/06—Inhaling appliances shaped like cigars, cigarettes or pipes
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24D—CIGARS; CIGARETTES; TOBACCO SMOKE FILTERS; MOUTHPIECES FOR CIGARS OR CIGARETTES; MANUFACTURE OF TOBACCO SMOKE FILTERS OR MOUTHPIECES
    • A24D1/00—Cigars; Cigarettes
    • A24D1/20—Cigarettes specially adapted for simulated smoking devices
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24D—CIGARS; CIGARETTES; TOBACCO SMOKE FILTERS; MOUTHPIECES FOR CIGARS OR CIGARETTES; MANUFACTURE OF TOBACCO SMOKE FILTERS OR MOUTHPIECES
    • A24D3/00—Tobacco smoke filters, e.g. filter-tips, filtering inserts; Filters specially adapted for simulated smoking devices; Mouthpieces for cigars or cigarettes
    • A24D3/17—Filters specially adapted for simulated smoking devices
    • A—HUMAN NECESSITIES
    • A24—TOBACCO; CIGARS; CIGARETTES; SIMULATED SMOKING DEVICES; SMOKERS' REQUISITES
    • A24F—SMOKERS' REQUISITES; MATCH BOXES; SIMULATED SMOKING DEVICES
    • A24F40/00—Electrically operated smoking devices; Component parts thereof; Manufacture thereof; Maintenance or testing thereof; Charging means specially adapted therefor
    • A24F40/20—Devices using solid inhalable precursors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/82—Internal energy supply devices
    • A61M2205/8206—Internal energy supply devices battery-operated

Definitions

  • the invention relates to a system for providing an inhalable aerosol and the components of such a system.
  • This system is particularly suitable as a smoking article for providing smoke aerosol for smokers.
  • a cigarette-shaped smoking article in which the thermal energy of a glowing carbon element is transferred to an aluminum capsule which is arranged inside the cigarette and contains an aerosol-forming material.
  • a special film tobacco loaded with high amounts of glycerin is used as the aerosol-forming material.
  • Both of the aforementioned smoking articles have in common that the combustion gases of the heating element are inhaled with the smoke aerosol, which leads to an increased absorption of carbon monoxide by the smoker. Furthermore, the entire smoking article, which in contrast to conventional cigarettes maintains its length, must be disposed of after smoking. This leads to an increased incidence of complex residues and associated disposal problems.
  • Another disadvantage of the above-mentioned smoking articles is a lack of taste in the first and last strokes.
  • substrate portions arranged on a belt serve for aerosol formation.
  • the substrate portions are brought into contact with an electrical heating element step by step.
  • This design allows only small amounts of substrate and the use of tobacco as an aerosol generator is not possible.
  • the winding device required for the tape is space-consuming and requires a complicated feed mechanism.
  • the object of the present invention is to provide a system for providing an inhalable aerosol which has a simple basic structure and can in particular serve as a smoking article which offers a taste impression similar to that of conventional cigarettes, but when used, no bypass smoke is generated between the trains.
  • the system according to the invention for providing an inhalable aerosol is particularly suitable as a smoking article, the functioning of which is based on the heating of an aerosol-forming material during the trains.
  • a number of preferably cylindrical portions of substrate, each of which contains aerosol-forming material within an envelope, are located in a preferably linear or circular arrangement on a carrier.
  • Such a combination of substrate portions is smoked in a special inhaler, preferably a new portion of the substrate being heated by means of chemical or electrical energy with each puff.
  • the use of the smoking article prevents the formation of sidestream smoke during train breaks.
  • An average filter cigarette provides the smoker with six to ten puffs with approximately the same taste intensity.
  • the aim according to the invention namely to provide the smoker with a similar number of flavor-equivalent puffs, can hardly be achieved with the previously known smoking articles explained above.
  • the invention solves the problem by using a new substrate portion instead of a single aerosol-forming element used for all trains. Less preferred, but also possible, is the use of one substrate portion for two or more trains.
  • the system according to the invention thus has the advantages of a constant range of smoking products and a simple construction.
  • La is a perspective view of a substrate portion from a composite of substrate portions according to the invention.
  • FIG. 1b shows a longitudinal section through the substrate portion according to FIG. 1a
  • FIG. 1c shows a cross section through the substrate portion according to FIG. 1a
  • FIG. 2a shows a perspective view of a composite of substrate portions according to the invention, the substrate portions are arranged on a disc-shaped carrier,
  • FIG. 2b shows a perspective view of another embodiment of a composite of substrate portions according to FIG.
  • FIG. 2c shows a perspective view of a further embodiment of a composite of substrate portions according to the invention, the substrate portions being arranged on a band-shaped linear carrier,
  • 3a shows a schematic illustration of an indirect heating principle for a substrate portion
  • 3b is a schematic illustration of a direct heating principle for a portion of substrate
  • FIG. 4a is an end view of an inhalation device according to the invention with a composite of substrate portions arranged on a disc-shaped carrier and an inserted mouthpiece,
  • FIG. 4b shows a schematic longitudinal section through the system according to FIG. 4a
  • FIG. 5a shows an end view of another embodiment of an inhalation device according to the invention with a composite of substrate portions arranged on a linear carrier and an inserted mouthpiece, and
  • FIG. 5b shows a schematic longitudinal section through the system according to FIG. 5a.
  • a preferred embodiment of a substrate portion 1 is shown in Figures la to lc.
  • the substrate portion 1 has a cylindrical shape, as can be seen from FIGS. 1 a to 1 c. It contains an aerosol-forming material 2, which is surrounded by a sheath 3 arranged radially (ie on the cylinder jacket).
  • the aerosol-forming material 2 can e.g. consist of cut leaf tobacco, cut tobacco ribs, reconstituted tobacco or a carrier material treated with aroma substances.
  • Leaf and rib cuts can also be used in expanded form, e.g. is obtained by using the method described in the patents DE 29 03 300, DE 31 19 330 and DE 34 14 625. Both organic materials such as e.g. Paper, as well as inorganic such as Silica gel are used. Any mixtures of the components mentioned can also be used.
  • material 2 contains from about 3% to 30% of an evaporable polyol, e.g. Glycerin or propylene glycol to increase aerosol formation.
  • an evaporable polyol e.g. Glycerin or propylene glycol
  • Another way of increasing aerosol formation is to use the aerosol-forming materials with a moisture which is significantly above the equilibrium moisture. For example, Tobacco, whose equilibrium moisture is around 10% to 12%, can be used with a moisture content of 20%. In this case, suitable packaging must be used to ensure that there is no loss of moisture until use.
  • the envelope 3 can consist of paper, plastic or metal foil. A multi-layer covering made of the components mentioned can also be used. However, a single-layer wrapping made of paper or metal-coated paper is preferred. In a further preferred embodiment, the casing 3 has a defined electrical conductivity. This can be done, for example, by Use of materials such as carbon-containing or metallized paper or a plastic film, in which conductive particles are incorporated, can be achieved.
  • the substrate portions 1 can be produced in a simple manner on a conventional cigarette rod machine: First, an endless strand of tobacco or replacement material is formed in a format part; this is surrounded by the wrapping material supplied in the direction of manufacture by a bobbin and glued to the seam. Then cut to the desired dimensions. Another possibility of production is the extrusion of a suitable aerosol-forming material through a round die with subsequent wrapping and cutting of the extrudate.
  • the diameter of a substrate portion 1 is preferably in the range from 3 mm to 10 mm and the length in the range from 3 mm to 30 mm. Diameters from 4 mm to 7 mm and lengths from 5 mm to 15 mm are particularly preferred.
  • the substrate portions 1 obtained are combined to form a composite of substrate portions.
  • a composite of substrate portions e.g.
  • eight of these portions must be connected to one another in order to achieve a handling comparable to that of the conventional cigarette. It is also possible, but less preferred, to use one substrate portion for several trains.
  • the substrate portions 1 can be connected in various ways on any carrier materials (for example made of cardboard or plastic). Preferred arrangements are shown in Figures 2a, 2b and 2c. In the arrangement according to FIG. 2a, the substrate portions 1 are arranged in a circle in the cutouts of a carrier disk 5. A similar arrangement on a linear carrier 6 is shown in FIG. 2b. By applying the substrate Portions 1 on a band-shaped carrier 7 give the arrangement shown in FIG. 2c. The band-shaped carrier 7 is also linear, but can be flexible. The substrate portions 1 can be attached to the respective carrier 5, 6 or 7, for example by gluing.
  • an inhalation device (hereinafter called smoking device) in which the smoke aerosol is released from the individual substrate portions.
  • FIG. 3a the substrate portion 1 is traversed by a gas heated in the smoking device during the train. This gas, together with air and the released aerosol, forms the smoke inhaled by the user.
  • a holder for the substrate portions 1 mounted on a circular carrier disk 5 is designed such that the carrier disk 5 is rotatably mounted about a bolt 24.
  • This pin 24 can either be part of the smoking device or of the combination of substrate portions having the substrate portions 1 and the carrier disk 5. Due to the rotatable mounting, the substrate portions 1 can be moved in succession with the aid of the transport device, not shown be brought into an operating position (smoking position); the substrate portion located there is designated la.
  • a radially symmetrical receiving device 21 is arranged in the housing 20 so as to be displaceable in the axial direction.
  • the receiving device 21 In the smoke position, the receiving device 21 is pressed by the force of a helical spring 22 against the substrate portion 1 a and this in turn against a combustion chamber 30.
  • a conical sealing surface 23 With the help of a conical sealing surface 23, a largely gas-tight seal between the substrate portion 1 a and the receiving device 21 is achieved.
  • a further transport of the substrate portions 1 is made possible by moving the receiving device 21 against the force of the coil spring 22.
  • the receiving device 21 is provided with a bore for receiving a mouthpiece 10, the inside diameter of which corresponds approximately to the outside diameter of the mouthpiece 10.
  • the combustion chamber 30 is connected to the outside of the smoking device through one or more bores 31. As a result, air 32 can get into the combustion chamber 30 in order to enable combustion on the one hand and air to be drawn through the substrate portion 1 a on the other hand.
  • a catalyst wire or network 33, a gas nozzle 34 and an ignition electrode 35 are located in the combustion chamber.
  • the housing 20 contains a gas tank 41 which can be refilled from the outside with compressed, combustible gases and is connected to the nozzle 34 via a valve 36, as well as a battery and controller 40 via which the valve 36 and the ignition electrode 35 are actuated electrically become.
  • a gas tank 41 which can be refilled from the outside with compressed, combustible gases and is connected to the nozzle 34 via a valve 36, as well as a battery and controller 40 via which the valve 36 and the ignition electrode 35 are actuated electrically become.
  • the use of the smoking device proceeds as follows: First, the circular combination of substrate portions 1 is placed in the smoking device so that the first substrate portion is in the
  • Smoking position la is located.
  • a new mouthpiece 10 with one Filter is inserted into the bore of the receiving device 21.
  • the force of the helical spring 22 creates a tight connection between the receiving device 21, the mouthpiece 10, the substrate portion 1 a and the combustion chamber 30.
  • a switch is actuated, which triggers the battery-operated control 40. This causes the valve 36 to open for a limited time, so that combustible gas from the gas tank 41 enters the combustion chamber 30 through the nozzle 34.
  • a spark is generated by applying an ignition voltage to the electrode 35, which causes the gas to ignite when air is admitted through the bore 31 on the catalyst 33.
  • the combustion produces a hot gas mixture which can be drawn through the substrate portion la together with air entering through the bores 31 and releases the smoke aerosol there.
  • the gas supply is interrupted and the next substrate portion 1 is brought into the smoking position with the aid of the transport device.
  • the smoking device is now ready to take the next train. After all substrate portions have been smoked, the composite of substrate portions 1 and the mouthpiece 10 are removed and disposed of.
  • FIGS. 5a front view
  • 5b longitudinal section
  • a holder for a composite of substrate portions which has substrate portions 1 with an electrically conductive covering 3 ′ attached to a linear carrier 6, is designed such that the carrier 6 is displaceable in its longitudinal direction.
  • a radially symmetrical receiving device 51 is arranged in the housing 50 so as to be displaceable in the axial direction. In the smoking position, the receiving device 51 is pressed by the force of a helical spring 52 against the substrate portion 1b and this in turn against a contact 54. With the help of a conical sealing surface
  • the receiving device 51 is provided with a bore for receiving a mouthpiece 10, the inside diameter of which corresponds approximately to the outside diameter of the mouthpiece 10.
  • the ring-shaped contact 54 is connected to the outside of the smoking device via a pipe 55. This allows air 56 to be drawn through the substrate portion 1b.
  • the housing 50 contains a battery or a rechargeable accumulator 61 and control electronics 60, the outputs of which are electrically connected to the receiving device 51 and the contact 54.
  • this smoking device proceeds as follows: First, the composite of substrate portions 1 is placed in the smoking device in such a way that the first substrate portion is in the smoking position 1b. A new filter mouthpiece 10 is inserted into the bore of the receiving device 51. After releasing a lock, the force of the helical spring 52 creates a tight and electrically conductive connection between the receiving device 51, the substrate portion 1b and the contact
  • a switch is operated to remove a train. that triggers the controller 60. This causes a time-limited current flow through the conductive sheath 3 'of the substrate portion 1b serving as a heating resistor, which heats or heats it and releases the smoke aerosol. Air 56 entering through the tube 55 can now be drawn through the substrate portion 1b and the mouthpiece 10. After removing the train, the power supply is interrupted and the next substrate portion 1 is brought into the smoking position with the aid of the transport device. The smoking device is now ready to take the next train. After all substrate portions have been smoked, the composite of substrate portions 1 and mouthpiece 10 are removed and disposed of.
  • the mouthpiece consists of a hollow roll of paper or cardboard.
  • the design as a filter mouthpiece is preferred.
  • a filter material such as cellulose acetate, polypropylene or paper is provided with a single or multi-layer coating.
  • a construction corresponding to the known multiple filters can also be used, in which several segments with different properties are arranged one behind the other in the axial direction and are connected by an outer covering. In this case, one or more segments can be provided with axial bores.
  • an endless strand with a diameter of 6 mm and a plug density of 200 mg / ml was produced on a cigarette rod machine.
  • the wrapping material used was an aluminum-laminated, air-impermeable paper on the outside.
  • the endless strand was cut into individual portions of 8 mm in length.
  • a paper film tobacco produced by known processes with a propylene glycol content of 12% by weight was cut with a cutting width of 0.8 mm, fed to a cigarette rod making machine as in Example 1 and wrapped in a cigarette paper in the cigarette paper, the cigarette paper permeability to air from 5 CU to ies.
  • the endless strand to length substrate portions with the same dimensions as in Example 1 were obtained; the plug density was 240 mg / ml.
  • the substrate portions were connected and smoked as in Example 1. No formation of sidestream smoke was found. The taste was assessed by subjects as uniform and pleasant over the features.

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cigarettes, Filters, And Manufacturing Of Filters (AREA)

Abstract

L'invention concerne un système permettant de préparer un aérosol inhalable. Cet aérosol comprend un ensemble de parties substrat et un dispositif d'inhalation. L'ensemble de parties substrat comporte un certain nombre de parties substrat (1) placées sur un support (5). Chacune des parties substrat (1), logée dans une enveloppe dotée d'un orifice d'entrée d'air et d'un orifice de sortie d'aérosol, contient une matière formant l'aérosol. Le dispositif d'inhalation a un boîtier (20), un élément de fixation (24, 23) destiné à l'ensemble de parties substrat et un dispositif chauffant (30, 33, 34, 35, 36, 40). Ce système est conçu de telle façon que chaque partie substrat de l'ensemble puisse être amenée dans une position opérationnelle (1a) et, dans cette position opérationnelle (1a), puisse être chauffée pour former l'aérosol. Lorsqu'une partie substrat est en position opérationnelle (1a), un embout (10) est raccordé à l'orifice de sortie d'aérosol.
PCT/EP1999/008429 1998-11-12 1999-11-08 Systeme permettant de preparer un aerosol inhalable WO2000028844A1 (fr)

Priority Applications (2)

Application Number Priority Date Filing Date Title
AU15510/00A AU1551000A (en) 1998-11-12 1999-11-08 System for supplying an inhalable aerosol
EP99957990A EP1128742A1 (fr) 1998-11-12 1999-11-08 Systeme permettant de preparer un aerosol inhalable

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19854012A DE19854012C2 (de) 1998-11-12 1998-11-12 System zur Bereitstellung eines inhalierbaren Aerosols
DE19854012.4 1998-11-12

Publications (1)

Publication Number Publication Date
WO2000028844A1 true WO2000028844A1 (fr) 2000-05-25

Family

ID=7888734

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP1999/008429 WO2000028844A1 (fr) 1998-11-12 1999-11-08 Systeme permettant de preparer un aerosol inhalable

Country Status (4)

Country Link
EP (1) EP1128742A1 (fr)
AU (1) AU1551000A (fr)
DE (1) DE19854012C2 (fr)
WO (1) WO2000028844A1 (fr)

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US7488171B2 (en) 2002-10-25 2009-02-10 R.J. Reynolds Tobacco Company Gas micro burner
WO2014127446A1 (fr) * 2013-02-25 2014-08-28 9208-8699 Québec Inc. Dispositif de vaporisation électronique portatif
US8991387B2 (en) 2003-05-21 2015-03-31 Alexza Pharmaceuticals, Inc. Self-contained heating unit and drug-supply unit employing same
US9687487B2 (en) 2001-06-05 2017-06-27 Alexza Pharmaceuticals, Inc. Aerosol forming device for use in inhalation therapy
EP3397088A4 (fr) * 2016-10-10 2019-07-10 Lik Hon Article pour fumer chauffant par combustion de gaz
EP3491944B1 (fr) 2006-10-18 2020-05-27 RAI Strategic Holdings, Inc. Article à fumer contenant du tabac
EP3484316B1 (fr) 2016-07-14 2020-11-25 British American Tobacco (Investments) Limited Embout buccal
US11642473B2 (en) 2007-03-09 2023-05-09 Alexza Pharmaceuticals, Inc. Heating unit for use in a drug delivery device
US11659868B2 (en) 2014-02-28 2023-05-30 Rai Strategic Holdings, Inc. Control body for an electronic smoking article
US11779051B2 (en) 2011-08-09 2023-10-10 Rai Strategic Holdings, Inc. Smoking articles and use thereof for yielding inhalation materials

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EP1989946A1 (fr) * 2007-05-11 2008-11-12 Rauchless Inc. Dispositif à fumer, supports de chargement et son procédé d'utilisation
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EP2227973B1 (fr) * 2009-03-12 2016-12-28 Olig AG Cigarette sans fumée
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EP2305051A1 (fr) * 2009-10-05 2011-04-06 Wedegree GmbH Système de remplissage de gaz liquide pour un substitut de cigarette sans fumée
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EP2753202B1 (fr) 2011-09-06 2016-04-27 British American Tobacco (Investments) Ltd Chauffage de matériau fumable
WO2013083635A1 (fr) * 2011-12-07 2013-06-13 Philip Morris Products S.A. Dispositif générateur d'aérosol ayant des entrées de flux d'air
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KR102328024B1 (ko) 2013-12-05 2021-11-17 쥴 랩스, 인크. 에어로졸 장치를 위한 니코틴 액제 및 그 방법
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AU1551000A (en) 2000-06-05

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