WO2000008134A3 - SERINE PROTEASE DE HtrA HUMAINE - Google Patents
SERINE PROTEASE DE HtrA HUMAINE Download PDFInfo
- Publication number
- WO2000008134A3 WO2000008134A3 PCT/EP1999/005528 EP9905528W WO0008134A3 WO 2000008134 A3 WO2000008134 A3 WO 2000008134A3 EP 9905528 W EP9905528 W EP 9905528W WO 0008134 A3 WO0008134 A3 WO 0008134A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- compounds
- invention concerns
- human
- serine protease
- methods
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
- C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
- C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
- C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
- C12N9/6424—Serine endopeptidases (3.4.21)
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Abstract
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU52904/99A AU5290499A (en) | 1998-08-03 | 1999-07-31 | Human htra serine protease |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/128,619 | 1998-08-03 | ||
US12861998A | 1998-10-26 | 1998-10-26 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO2000008134A2 WO2000008134A2 (fr) | 2000-02-17 |
WO2000008134A3 true WO2000008134A3 (fr) | 2000-05-11 |
Family
ID=22436199
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/EP1999/005528 WO2000008134A2 (fr) | 1998-08-03 | 1999-07-31 | SERINE PROTEASE DE HtrA HUMAINE |
Country Status (2)
Country | Link |
---|---|
AU (1) | AU5290499A (fr) |
WO (1) | WO2000008134A2 (fr) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO2008067040A2 (fr) * | 2006-10-06 | 2008-06-05 | University Of Utah Research Foundation | Procédé de détection de maladies et d'affections pathologiques de l'œil et traitement de celles-ci |
EP2217720A4 (fr) | 2007-11-01 | 2010-12-08 | Univ Iowa Res Found | Analyse de lieu de rca pour estimer la sensibilité à l'amd et au mpgnii |
EA201490778A1 (ru) | 2011-10-14 | 2014-09-30 | Дженентек, Инк. | АНТИТЕЛА ПРОТИВ HtrA1 И СПОСОБЫ ПРИМЕНЕНИЯ |
EP3922649B1 (fr) | 2015-10-30 | 2024-01-17 | F. Hoffmann-La Roche AG | Anticorps anti-htra1 et leurs procédés d'utilisation |
EA201990069A1 (ru) | 2016-06-21 | 2019-06-28 | ОРИОН ОФТАЛМОЛОДЖИ ЭлЭлСи | Производные гетероциклического пролинамида |
JP7164521B2 (ja) | 2016-06-21 | 2022-11-01 | オリオン・オフサルモロジー・エルエルシー | 炭素環式プロリンアミド誘導体 |
CR20180606A (es) | 2016-07-01 | 2019-02-14 | Hoffmann La Roche | Oligonucleótidos antisentido para modular la expresión de htra1 |
US20190055564A1 (en) * | 2017-06-01 | 2019-02-21 | F. Hoffmann-La Roche Ag | Antisense oligonucleotides for modulating htra1 expression |
BR112020012523A2 (pt) * | 2017-12-21 | 2020-11-24 | F. Hoffmann-La Roche Ag | diagnóstico complementar para antagonistas de rna htra1 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH09107980A (ja) * | 1995-08-17 | 1997-04-28 | Japan Tobacco Inc | 新規生理活性タンパク |
EP0828003A2 (fr) * | 1996-09-06 | 1998-03-11 | Smithkline Beecham Plc | Sérine protéase humaine |
-
1999
- 1999-07-31 AU AU52904/99A patent/AU5290499A/en not_active Abandoned
- 1999-07-31 WO PCT/EP1999/005528 patent/WO2000008134A2/fr active Application Filing
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH09107980A (ja) * | 1995-08-17 | 1997-04-28 | Japan Tobacco Inc | 新規生理活性タンパク |
EP0828003A2 (fr) * | 1996-09-06 | 1998-03-11 | Smithkline Beecham Plc | Sérine protéase humaine |
Non-Patent Citations (3)
Title |
---|
HU ET AL.: "Human HtrA, an evolutionarily conserved serine protease identified as a differentially expressed gene product in osteoarthritic cartilage", J. BIOL. CHEM., vol. 273, no. 51, 18 December 1998 (1998-12-18), pages 34406 - 34412, XP002127797 * |
PATENT ABSTRACTS OF JAPAN vol. 1997, no. 08 29 August 1997 (1997-08-29) * |
ZUMBRUNN ET AL.: "Primary structure of a putative serine protease specific for IGF-binding proteins", FEBS LETTERS, vol. 398, 1996, pages 187 - 192, XP002127796 * |
Also Published As
Publication number | Publication date |
---|---|
AU5290499A (en) | 2000-02-28 |
WO2000008134A2 (fr) | 2000-02-17 |
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