WO1999002704A3 - Phosphatase a double specificite et procedes d'utilisation - Google Patents
Phosphatase a double specificite et procedes d'utilisation Download PDFInfo
- Publication number
- WO1999002704A3 WO1999002704A3 PCT/US1998/014205 US9814205W WO9902704A3 WO 1999002704 A3 WO1999002704 A3 WO 1999002704A3 US 9814205 W US9814205 W US 9814205W WO 9902704 A3 WO9902704 A3 WO 9902704A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- pten
- methods
- phosphatase
- dual
- specifically
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/14—Hydrolases (3)
- C12N9/16—Hydrolases (3) acting on ester bonds (3.1)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Abstract
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU84794/98A AU8479498A (en) | 1997-07-08 | 1998-07-08 | Dual specificity phosphatase and methods of use |
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US5190897P | 1997-07-08 | 1997-07-08 | |
US60/051,908 | 1997-07-08 | ||
US9098498P | 1998-06-29 | 1998-06-29 | |
US60/090,984 | 1998-06-29 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO1999002704A2 WO1999002704A2 (fr) | 1999-01-21 |
WO1999002704A3 true WO1999002704A3 (fr) | 1999-04-01 |
Family
ID=26729940
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US1998/014205 WO1999002704A2 (fr) | 1997-07-08 | 1998-07-08 | Phosphatase a double specificite et procedes d'utilisation |
Country Status (2)
Country | Link |
---|---|
AU (1) | AU8479498A (fr) |
WO (1) | WO1999002704A2 (fr) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6248327B1 (en) | 1998-09-11 | 2001-06-19 | Vanderbilt University | Modulation of endothelial cell surface receptor activity in the regulation of angiogenesis |
WO2000060092A2 (fr) * | 1999-04-07 | 2000-10-12 | Ceptyr, Inc. | Phosphatase a specificite double dsp-3 |
AU4367600A (en) * | 1999-07-02 | 2001-01-22 | Ceptyr, Inc. | Dsp-3 dual-specificity phosphatase |
US7078210B2 (en) | 1999-07-02 | 2006-07-18 | Ceptyr, Inc. | DSP-3 dual-specificity phosphatase |
US6284538B1 (en) | 1999-07-21 | 2001-09-04 | Isis Pharmaceuticals, Inc. | Antisense inhibition of PTEN expression |
JP2003507016A (ja) * | 1999-08-13 | 2003-02-25 | スージェン・インコーポレーテッド | 新規な蛋白質ホスファターゼおよびホスファターゼ関連疾患の診断および治療 |
AU2001247782A1 (en) * | 2000-03-24 | 2001-10-08 | Millennium Pharmaceuticals, Inc. | 18221, dual specificity phosphatase and uses thereof |
EP1289472A4 (fr) * | 2000-05-30 | 2004-09-08 | Advanced Res & Tech Inst | Compositions et methodes d'identification d'agents modulateurs de la fonction pten et des mecanismes de la pi-3 kinase |
KR20040018598A (ko) * | 2002-08-23 | 2004-03-04 | 코웰창업투자(주) | Tat-PTEN 융합 단백질, 이의 제조 방법 및 용도 |
US20040106141A1 (en) * | 2002-11-05 | 2004-06-03 | The Regents Of The University Of California | Methods and materials for examining pathways associated with glioblastoma progression |
US20040225077A1 (en) | 2002-12-30 | 2004-11-11 | Angiotech International Ag | Drug delivery from rapid gelling polymer composition |
WO2004074459A2 (fr) * | 2003-02-19 | 2004-09-02 | Georgetown University | Cellules deficientes en pten et utilisations de celles-ci |
CA2777628C (fr) * | 2009-10-16 | 2019-12-03 | The University Of British Columbia | Compositions d'inhibiteurs de phosphatase et d'homologue de tensine (pten), utilisations et procedes |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1997015686A1 (fr) * | 1995-10-23 | 1997-05-01 | Imperial Cancer Research Technology Limited | Diagnostic de predisposition au cancer et traitement approprie |
WO1998033907A1 (fr) * | 1997-01-30 | 1998-08-06 | Board Of Regents, The University Of Texas System | Suppresseur tumoral ts10q23.3 |
WO1998034624A1 (fr) * | 1997-02-07 | 1998-08-13 | The Trustees Of Columbia University In The City Of New York | Utilisation du gene suppresseur de tumeur p-ten dans le diagnostic et le traitement de cancer |
-
1998
- 1998-07-08 AU AU84794/98A patent/AU8479498A/en not_active Abandoned
- 1998-07-08 WO PCT/US1998/014205 patent/WO1999002704A2/fr active Application Filing
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1997015686A1 (fr) * | 1995-10-23 | 1997-05-01 | Imperial Cancer Research Technology Limited | Diagnostic de predisposition au cancer et traitement approprie |
WO1998033907A1 (fr) * | 1997-01-30 | 1998-08-06 | Board Of Regents, The University Of Texas System | Suppresseur tumoral ts10q23.3 |
WO1998034624A1 (fr) * | 1997-02-07 | 1998-08-13 | The Trustees Of Columbia University In The City Of New York | Utilisation du gene suppresseur de tumeur p-ten dans le diagnostic et le traitement de cancer |
Non-Patent Citations (9)
Title |
---|
DATABASE EMBL - EMHUM2 3 April 1997 (1997-04-03), LI, J. ET AL.: "Human putative protein tyrosine phosphatase (PTEN) mRNA, complete cds.", XP002066159 * |
DATABASE EMBL - EMHUM2 3 April 1997 (1997-04-03), STECK, P.A. ET AL.: "Human mutated in multiple advanced cancers protein (MMAC1) mRNA, complete cds.", XP002066161 * |
LI, D-M. ET AL.: "TEP1, encoded by a candidate tumor suppressor locus, is a novel protein tyrosine phosphatase regulated by transforming growth factor beta.", CANCER RESEARCH, vol. 57, 1 June 1997 (1997-06-01), pages 2124 - 2129, XP002066157 * |
LI, J. ET AL.: "PTEN, a putative tyrosine phosphatase gene mutated in human brain, breast, and prostate cancer.", SCIENCE, vol. 275, 28 March 1997 (1997-03-28), pages 1943 - 1946, XP002066155 * |
MAEHAMA, T. ET AL.: "The tumor suppressor, PTEN/MMAC1, dephosphorylates the lipid second messenger, phosphatidylinositol 3,4,5-triphosphate.", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 273, no. 22, 29 May 1998 (1998-05-29), pages 13375 - 8, XP002088259 * |
MYERS, M. ET AL.: "P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatse.", PROC.NATL.ACAD.SCI.USA, vol. 94, August 1997 (1997-08-01), XP002088258 * |
PAYRASTRE, B. ET AL.: "Phosphoinositide 3-phosphatase segregates from phosphatidylinositol 3-kinase in EGF-stimulated A431 cells and fails to in vitro hydrolyse phosphatidylinositol(3,4,5)trisphosphate.", FEBS LETTERS, vol. 341, 1994, pages 113 - 8, XP002088256 * |
STECK, P.A. ET AL.: "Identification of a candidate tumor suppressor gene at 10q23.3 that is mutated in multiple advanced cancers, MMAC1.", NATURE GENETICS, vol. 15, April 1997 (1997-04-01), pages 356 - 363, XP002066156 * |
ZHOU, G. ET AL.: "The catalytic role of Cys124 in the dual specificity phosphatase VHR.", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 269, no. 45, 11 November 1994 (1994-11-11), pages 28084 - 90, XP002088257 * |
Also Published As
Publication number | Publication date |
---|---|
WO1999002704A2 (fr) | 1999-01-21 |
AU8479498A (en) | 1999-02-08 |
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