WO1999054461A3 - Menschliche nukleinsäuresequenzen aus endometriumtumorgewebe - Google Patents

Menschliche nukleinsäuresequenzen aus endometriumtumorgewebe Download PDF

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Publication number
WO1999054461A3
WO1999054461A3 PCT/DE1999/001174 DE9901174W WO9954461A3 WO 1999054461 A3 WO1999054461 A3 WO 1999054461A3 DE 9901174 W DE9901174 W DE 9901174W WO 9954461 A3 WO9954461 A3 WO 9954461A3
Authority
WO
WIPO (PCT)
Prior art keywords
nucleic acid
acid sequences
tumour tissue
human nucleic
endometrium
Prior art date
Application number
PCT/DE1999/001174
Other languages
English (en)
French (fr)
Other versions
WO1999054461A2 (de
Inventor
Thomas Specht
Bernd Hinzmann
Armin Schmitt
Christian Pilarsky
Edgar Dahl
Andre Rosenthal
Original Assignee
Metagen Gesellschaft Fuer Genomforschung Mbh
Thomas Specht
Bernd Hinzmann
Armin Schmitt
Christian Pilarsky
Edgar Dahl
Andre Rosenthal
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Metagen Gesellschaft Fuer Genomforschung Mbh, Thomas Specht, Bernd Hinzmann, Armin Schmitt, Christian Pilarsky, Edgar Dahl, Andre Rosenthal filed Critical Metagen Gesellschaft Fuer Genomforschung Mbh
Priority to US09/673,395 priority Critical patent/US6620923B1/en
Priority to JP2000544793A priority patent/JP2002532055A/ja
Priority to EP99923403A priority patent/EP1071775A2/de
Publication of WO1999054461A2 publication Critical patent/WO1999054461A2/de
Publication of WO1999054461A3 publication Critical patent/WO1999054461A3/de

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Es werden menschliche Nukleinsäuresequenzen-mRNA, cDNA, genomische Sequenzen - aus Endometriumtumor, die für Genprodukte oder Teile davon kodieren, und deren Verwendung beschrieben. Es werden weiterhin die über die Sequenzen erhältlichen Polypeptide und deren Verwendung beschrieben.
PCT/DE1999/001174 1998-04-17 1999-04-15 Menschliche nukleinsäuresequenzen aus endometriumtumorgewebe WO1999054461A2 (de)

Priority Applications (3)

Application Number Priority Date Filing Date Title
US09/673,395 US6620923B1 (en) 1998-04-17 1999-04-15 Human nucleic acid sequences from endometrial tumor tissue
JP2000544793A JP2002532055A (ja) 1998-04-17 1999-04-15 子宮内膜腫瘍組織からのヒト核酸配列
EP99923403A EP1071775A2 (de) 1998-04-17 1999-04-15 Menschliche nukleinsäuresequenzen aus endometriumtumorgewebe

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19817948.0 1998-04-17
DE19817948A DE19817948A1 (de) 1998-04-17 1998-04-17 Menschliche Nukleinsäuresequenzen aus Endometrium-Tumor

Publications (2)

Publication Number Publication Date
WO1999054461A2 WO1999054461A2 (de) 1999-10-28
WO1999054461A3 true WO1999054461A3 (de) 2000-07-06

Family

ID=7865426

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/DE1999/001174 WO1999054461A2 (de) 1998-04-17 1999-04-15 Menschliche nukleinsäuresequenzen aus endometriumtumorgewebe

Country Status (5)

Country Link
US (1) US6620923B1 (de)
EP (1) EP1071775A2 (de)
JP (1) JP2002532055A (de)
DE (1) DE19817948A1 (de)
WO (1) WO1999054461A2 (de)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020137890A1 (en) * 1997-03-31 2002-09-26 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
US20030003507A1 (en) 1999-06-02 2003-01-02 Genentech, Inc. Compositions and methods for the diagnosis and treatment of tumor
US7014996B1 (en) 1998-10-02 2006-03-21 Diadexus, Inc. Method of diagnosing, monitoring, staging, imaging and treating gynecologic cancers
CA2353102A1 (en) * 1998-12-01 2000-06-08 Sumitomo Pharmaceuticals Company, Limited Novel tumor antigen protein art-1 and tumor antigen peptide thereof
WO2000043513A1 (en) * 1999-01-21 2000-07-27 Millennium Pharmaceuticals, Inc. 17723 receptor, a g-protein coupled receptor
JP2002539826A (ja) * 1999-03-26 2002-11-26 スミスクライン ビーチャム バイオロジカルズ ソシエテ アノニム 新規化合物
US6951738B2 (en) 1999-07-16 2005-10-04 Human Genome Sciences, Inc. Human tumor necrosis factor receptors TR13 and TR14
WO2001009328A1 (en) 1999-08-03 2001-02-08 Millennium Pharmaceuticals, Inc. 15571, a novel gpcr-like molecule of the secretin-like family and uses thereof
CA2385235A1 (en) * 1999-09-23 2001-03-29 Rigel Pharmaceuticals, Inc. Checkpoint gene associated cell cycle proteins, compositions and methods of use
FR2800388A1 (fr) * 1999-10-29 2001-05-04 Pf Medicament Clonage, expression et caracterisation d'un gene exprime dans des cellules tumorales et implique dans la regulation de la reponse immune
ES2171104B1 (es) * 1999-11-29 2003-12-16 Univ Oviedo Procedimiento de identificacion de la metaloproteasa humana matrilisina-2.
FR2802945A1 (fr) * 1999-12-28 2001-06-29 Pf Medicament Nouvelle metalloprotease matricielle mmp-25 homologue de la matrilysine
AU6802801A (en) * 2000-03-01 2001-09-24 Genentech Inc Secreted and transmembrane polypeptides and nucleic acids encoding the same
WO2001070976A2 (en) * 2000-03-21 2001-09-27 Corixa Corporation Compositions and methods for the therapy and diagnosis of ovarian and endometrial cancer
WO2001090324A2 (en) * 2000-05-19 2001-11-29 Millennium Pharmaceuticals, Inc. 32263, a putative human biotin transcarboxylase and uses thereof
JP2004500852A (ja) * 2000-05-19 2004-01-15 エフ. ホフマン−ラ ロシュ アーゲー ヒト腫瘍細胞においてダウンレギュレートされる核酸の使用による、試料の殺腫瘍能を決定するためのプロセス
US20020068691A1 (en) * 2000-06-21 2002-06-06 Susana Salceda Method of diagnosing, monitoring, staging, imaging and treating breast cancer
US20020168647A1 (en) * 2000-08-03 2002-11-14 Tongtong Wang Compositions and methods for the therapy and diagnosis of head and neck cancer
WO2002018632A2 (de) * 2000-09-01 2002-03-07 Epigenomics Ag Verfahren zur bestimmung des methylierungsgrades von bestimmten cytosinen in genomischer dna im sequenzkontext 5'-cpg-3'
AU2002253104A1 (en) * 2001-03-07 2002-09-19 Galapagos Genomics B.V. Adenoviral library assay for e2f regulatory genes and methods and compositions for screening compounds
US20030211039A1 (en) * 2001-05-29 2003-11-13 Macina Roberto A. Method of diagnosing, monitoring, staging, imaging and treating colon cancer
US7622260B2 (en) 2001-09-05 2009-11-24 The Brigham And Women's Hospital, Inc. Diagnostic and prognostic tests
WO2003028543A2 (en) * 2001-10-03 2003-04-10 Pfizer Products Inc. Nucleic acid molecules, polypeptides and uses therefor, including diagnosis and treatment of alzheimer's disease
CA2527863A1 (en) * 2003-06-02 2004-12-23 Alexion Pharmaceuticals, Inc. Cell surface protein associated with human chronic lymphocytic leukemia
WO2007079075A2 (en) * 2005-12-31 2007-07-12 Genentech, Inc. Phosphorylated cop1 molecules and uses thereof
JP5421374B2 (ja) 2008-09-03 2014-02-19 ザ・ジョンズ・ホプキンス・ユニバーシティー 悪性神経膠腫におけるイソクエン酸デヒドロゲナーゼ遺伝子および他の遺伝子の遺伝子変化
EP2326669A2 (de) * 2008-09-04 2011-06-01 Oxford Biotherapeutics Ltd. Pta072-protein
WO2011119595A1 (en) * 2010-03-22 2011-09-29 Auburn University Phage constructs, sequences and antigenic compositions for immunocontraception of animals
WO2021202816A1 (en) * 2020-03-31 2021-10-07 The Administrators Of The Tulane Educational Fund Broad-spectrum antiviral peptides
WO2022172264A1 (en) * 2021-02-11 2022-08-18 Ramot At Tel Aviv University Ltd. Compositions and methods for treating a disease

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6174992B1 (en) * 1997-03-21 2001-01-16 Human Genome Sciences, Inc. Human endometrial specific steroid-binding factor I, II and III
CA2248136A1 (en) * 1996-03-21 1997-09-25 Human Genome Sciences, Inc. Human endometrial specific steroid-binding factor i, ii and iii

Non-Patent Citations (8)

* Cited by examiner, † Cited by third party
Title
A. KOUL ET AL.: "A somatic BRCA2 mutation in RER+ endometrial carcinomas that specifically deletes the amino-terminal transactivation domain", GENES, CHROMOSOMES & CANCER, vol. 24, no. 3, March 1999 (1999-03-01), pages 207 - 212, XP002127135 *
ADAMS M.D. ET AL.: "EST41316 Endometrial tumor Homo sapiens cDNA 5' end.", EMBL ACCESSION NO. AA336687, 18 April 1997 (1997-04-18), XP002127129 *
ADAMS M.D. ET AL.: "EST41427 Endometrial tumor Homo sapiens cDNA 5' end.", EMBL ACCESSION NO. AA336787, 18 April 1997 (1997-04-18), XP002127130 *
E. STRUNCK ET AL.: "Basement membrane regulates gene expression in HEC1B(L) Endometrial adenocarcinoma cells.", BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS., vol. 221, no. 2, 1996, pages 346 - 350, XP002127131 *
M. SAKATA ET AL.: "Messenger RNA differential display reverse-transcriptase-polymerase-chain-reaction analysis of a progestogen-suppressive gene in a human endometrial-cancer cell line.", INTERNATIONAL JOURNAL OF CANCER, vol. 78, no. 1, 25 September 1998 (1998-09-25), pages 125 - 129, XP002127136 *
M.F. ARLT ET AL.: "Frequent deletion of chromosome 1p sequences in an aggressive histologic subtype of endometrial cancer.", HUMAN MOLECULAR GENETICS, vol. 5, no. 7, 1996, pages 1017 - 1021, XP002127133 *
MAHMOOD MANAVI, M.D. ET AL.: "Amplification and expression of the c-erbB-2 oncogene in Müllerian-derived Genital-tract tumors.", GYNECOLOGIC ONCOLOGY, vol. 71, no. 2, November 1998 (1998-11-01), pages 165 - 171, XP002127134 *
TO HOA THAI ET AL.: "Mutations in the BRCA1-associated RING domain (BARD1) gene in primary breast, ovarian and uterine cancers.", HUMAN MOLECULAR GENETICS, vol. 7, no. 2, 1998, pages 195 - 202, XP002127132 *

Also Published As

Publication number Publication date
US6620923B1 (en) 2003-09-16
JP2002532055A (ja) 2002-10-02
WO1999054461A2 (de) 1999-10-28
EP1071775A2 (de) 2001-01-31
DE19817948A1 (de) 1999-10-21

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