WO1999054447A3 - Menschliche nukleinsäuresequenzen aus blasentumorgewebe - Google Patents

Menschliche nukleinsäuresequenzen aus blasentumorgewebe Download PDF

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Publication number
WO1999054447A3
WO1999054447A3 PCT/DE1999/001170 DE9901170W WO9954447A3 WO 1999054447 A3 WO1999054447 A3 WO 1999054447A3 DE 9901170 W DE9901170 W DE 9901170W WO 9954447 A3 WO9954447 A3 WO 9954447A3
Authority
WO
WIPO (PCT)
Prior art keywords
nucleic acid
acid sequences
tumour tissue
human nucleic
bladder tumour
Prior art date
Application number
PCT/DE1999/001170
Other languages
English (en)
French (fr)
Other versions
WO1999054447A2 (de
Inventor
Thomas Specht
Bernd Hinzmann
Armin Schmitt
Christian Pilarsky
Edgar Dahl
Andre Rosenthal
Original Assignee
Metagen Gesellschaft Fuer Genomforschung Mbh
Thomas Specht
Bernd Hinzmann
Armin Schmitt
Christian Pilarsky
Edgar Dahl
Andre Rosenthal
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Metagen Gesellschaft Fuer Genomforschung Mbh, Thomas Specht, Bernd Hinzmann, Armin Schmitt, Christian Pilarsky, Edgar Dahl, Andre Rosenthal filed Critical Metagen Gesellschaft Fuer Genomforschung Mbh
Priority to JP2000544779A priority Critical patent/JP2002512023A/ja
Priority to EP99927682A priority patent/EP1073742A2/de
Publication of WO1999054447A2 publication Critical patent/WO1999054447A2/de
Publication of WO1999054447A3 publication Critical patent/WO1999054447A3/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/10Drugs for disorders of the urinary system of the bladder
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Urology & Nephrology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)

Abstract

Es werden menschliche Nukleinsäuresequenzen - mRNA, cDNA, genomische Sequenzen - aus Blasentumorgewebe, die für Genprodukte oder Teile davon kodieren, und deren Verwendung beschrieben. Es werden weiterhin die über die Sequenzen erhältlichen Polypeptide und deren Verwendung beschrieben.
PCT/DE1999/001170 1998-04-21 1999-04-15 Menschliche nukleinsäuresequenzen aus blasentumorgewebe WO1999054447A2 (de)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2000544779A JP2002512023A (ja) 1998-04-21 1999-04-15 膀胱癌組織由来ヒト核酸配列
EP99927682A EP1073742A2 (de) 1998-04-21 1999-04-15 Menschliche nukleinsäuresequenzen aus blasentumorgewebe

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19818619.3 1998-04-21
DE19818619A DE19818619A1 (de) 1998-04-21 1998-04-21 Menschliche Nukleinsäuresequenzen aus Blase-Tumor

Publications (2)

Publication Number Publication Date
WO1999054447A2 WO1999054447A2 (de) 1999-10-28
WO1999054447A3 true WO1999054447A3 (de) 2000-07-06

Family

ID=7865833

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/DE1999/001170 WO1999054447A2 (de) 1998-04-21 1999-04-15 Menschliche nukleinsäuresequenzen aus blasentumorgewebe

Country Status (4)

Country Link
EP (1) EP1073742A2 (de)
JP (1) JP2002512023A (de)
DE (1) DE19818619A1 (de)
WO (1) WO1999054447A2 (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6358508B1 (en) 1997-06-11 2002-03-19 Human Genome Sciences, Inc. Antibodies to human tumor necrosis factor receptor TR9
AU3316600A (en) 1999-02-22 2000-09-21 Torben F. Orntoft Gene expression in bladder tumors
US6573364B1 (en) * 1999-03-10 2003-06-03 Curagen Corporation Isolation and characterization of Hermansky Pudlak Syndrome (HPS) protein complexes and HPS protein-interacting proteins
IL148798A0 (en) * 1999-09-27 2002-09-12 Quark Biotech Inc Sequences characteristic of bladder cancer
WO2001087238A2 (en) * 2000-05-17 2001-11-22 Oregon Health & Sciences University Induction of apoptosis and cell growth inhibition by protein 4.33
AU2003220387A1 (en) 2002-03-19 2003-10-08 Tularik Inc. Gene amplification in cancer
EP1590440A4 (de) * 2003-02-03 2009-03-18 Palo Alto Inst Of Molecular Me Zellabtötende moleküle und vefahren zu deren verwendung
DE10309729A1 (de) * 2003-02-26 2004-09-16 Hinzmann, Bernd, Dr. Humane Nukleinsäuresequenzen aus Harnblasenkarzinomen
JPWO2005093063A1 (ja) * 2004-03-29 2008-02-14 株式会社医学生物学研究所 固形癌診断キット及び固形癌治療用医薬
US8129340B2 (en) 2006-09-08 2012-03-06 Institut Gustave Roussy Inhibitors of protein phosphatase 1, GADD34 and protein phosphatase 1/GADD34 complex, preparation and uses thereof
EP1961762A1 (de) * 2007-02-21 2008-08-27 Institut Gustave Roussy Proteinphosphatase-1/GADD34-Inhibitoren, deren Herstellung und Verwendung
US8420315B2 (en) * 2007-08-06 2013-04-16 Orion Genomics Llc Single nucleotide polymorphisms and combinations of novel and known polymorphisms for determining the allele-specific expression of the IGF2 gene

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994001777A1 (en) * 1992-07-14 1994-01-20 Michigan Cancer Foundation Method of determining metastatic potential of tumor cells
WO1998054963A2 (en) * 1997-06-06 1998-12-10 Human Genome Sciences, Inc. 207 human secreted proteins

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1994001777A1 (en) * 1992-07-14 1994-01-20 Michigan Cancer Foundation Method of determining metastatic potential of tumor cells
WO1998054963A2 (en) * 1997-06-06 1998-12-10 Human Genome Sciences, Inc. 207 human secreted proteins

Non-Patent Citations (5)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL NUCLEOTIDE SEQU 1 January 1900 (1900-01-01), HOWDEN P: "Human DNA sequence from clone 328E19 on chromosome 1q12-21.2", XP002126938, Database accession no. AL022240 *
DATABASE EMBL NUCLEOTIDE SEQU 1 January 1900 (1900-01-01), XP002126939, Database accession no. AA774786 *
DATABASE EMBL NUCLEOTIDE SEQU 1 January 1900 (1900-01-01), XP002126940, Database accession no. AF131738 *
O'BRIEN, T. ET AL.: "The Angiogenic Factor Midkine Is Expressed in Bladder Cancer, and Overexpression Correlates with a Poor Outcome in Patients with invasive Cancers", CANCER RESEARCH, vol. 56, no. 11, 1 June 1996 (1996-06-01), pages 2515 - 2518, XP000857920 *
SCHMITT, A.O. ET AL.: "Exhaustive mining of EST libraries for genes differentially expressed in normal and tumor tissue", NUCLEIC ACIDS RESEARCH, vol. 27, no. 21, 1 November 1999 (1999-11-01), pages 4251 - 4260, XP002126641 *

Also Published As

Publication number Publication date
DE19818619A1 (de) 1999-10-28
JP2002512023A (ja) 2002-04-23
WO1999054447A2 (de) 1999-10-28
EP1073742A2 (de) 2001-02-07

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