WO1999055858A3 - Menschliche nukleinsäuresequenzen aus pankreastumorgewebe - Google Patents

Menschliche nukleinsäuresequenzen aus pankreastumorgewebe Download PDF

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Publication number
WO1999055858A3
WO1999055858A3 PCT/DE1999/001258 DE9901258W WO9955858A3 WO 1999055858 A3 WO1999055858 A3 WO 1999055858A3 DE 9901258 W DE9901258 W DE 9901258W WO 9955858 A3 WO9955858 A3 WO 9955858A3
Authority
WO
WIPO (PCT)
Prior art keywords
nucleic acid
tumor tissue
acid sequences
human nucleic
pancreas tumor
Prior art date
Application number
PCT/DE1999/001258
Other languages
English (en)
French (fr)
Other versions
WO1999055858A2 (de
Inventor
Thomas Specht
Bernd Hinzmann
Armin Schmitt
Christian Pilarsky
Edgar Dahl
Andre Rosenthal
Original Assignee
Metagen Gesellschaft Fuer Genomforschung Mbh
Thomas Specht
Bernd Hinzmann
Armin Schmitt
Christian Pilarsky
Edgar Dahl
Andre Rosenthal
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Metagen Gesellschaft Fuer Genomforschung Mbh, Thomas Specht, Bernd Hinzmann, Armin Schmitt, Christian Pilarsky, Edgar Dahl, Andre Rosenthal filed Critical Metagen Gesellschaft Fuer Genomforschung Mbh
Priority to EP99926275A priority Critical patent/EP1076700A2/de
Priority to JP2000546002A priority patent/JP2002512795A/ja
Publication of WO1999055858A2 publication Critical patent/WO1999055858A2/de
Publication of WO1999055858A3 publication Critical patent/WO1999055858A3/de

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/18—Drugs for disorders of the alimentary tract or the digestive system for pancreatic disorders, e.g. pancreatic enzymes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Zoology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)

Abstract

Es werden menschliche Nukleinsäuresequenzen - mRNA, cDNA, genomische Sequenzen - aus Pankreastumorgewebe, die für Genprodukte oder Teile davon kodieren, und deren Verwendung beschrieben. Es werden weiterhin die über die Sequenzen erhältlichen Polypeptide und deren Verwendung beschrieben.
PCT/DE1999/001258 1998-04-28 1999-04-19 Menschliche nukleinsäuresequenzen aus pankreastumorgewebe WO1999055858A2 (de)

Priority Applications (2)

Application Number Priority Date Filing Date Title
EP99926275A EP1076700A2 (de) 1998-04-28 1999-04-19 Menschliche nukleinsäuresequenzen aus pankreastumorgewebe
JP2000546002A JP2002512795A (ja) 1998-04-28 1999-04-19 膵臓癌組織由来ヒト核酸配列

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19820190.7 1998-04-28
DE19820190A DE19820190A1 (de) 1998-04-28 1998-04-28 Menschliche Nukleinsäuresequenzen aus Pankreas-Tumor

Publications (2)

Publication Number Publication Date
WO1999055858A2 WO1999055858A2 (de) 1999-11-04
WO1999055858A3 true WO1999055858A3 (de) 2000-06-15

Family

ID=7866827

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/DE1999/001258 WO1999055858A2 (de) 1998-04-28 1999-04-19 Menschliche nukleinsäuresequenzen aus pankreastumorgewebe

Country Status (4)

Country Link
EP (1) EP1076700A2 (de)
JP (1) JP2002512795A (de)
DE (1) DE19820190A1 (de)
WO (1) WO1999055858A2 (de)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6541224B2 (en) 1996-03-14 2003-04-01 Human Genome Sciences, Inc. Tumor necrosis factor delta polypeptides
US7217788B2 (en) 1996-03-14 2007-05-15 Human Genome Sciences, Inc. Human tumor necrosis factor delta polypeptides
DE19817946A1 (de) * 1998-04-17 1999-10-21 Metagen Gesellschaft Fuer Genomforschung Mbh Menschliche Nukleinsäuresequenzen aus Uterus-Normalgewebe
US6949339B1 (en) 1998-05-21 2005-09-27 Diadexus, Inc. Method of diagnosing, monitoring, and staging colon cancer
CA2350776C (en) 1998-11-10 2011-05-03 Emory University Novel mitogenic regulators
EP1715043A3 (de) * 1998-12-23 2007-01-10 Corixa Corporation Verbindungen zur immunotherapie und diagnose von dickdarmkrebs und verfahren zu ihrer anwendung
AU2303800A (en) * 1999-01-26 2000-08-18 University College London Screen method
US7029912B1 (en) 1999-04-09 2006-04-18 Sugen, Inc. Tyrosine kinase substrate(Tks) proteins
CA2365623A1 (en) * 1999-04-09 2000-10-19 Sugen, Inc. Tyrosine kinase substrate (tks) proteins
US6696263B1 (en) 1999-09-23 2004-02-24 Rigel Pharmaceuticals, Inc. PCNA associated cell cycle proteins, compositions and methods of use
JP2003515328A (ja) * 1999-12-02 2003-05-07 アイシス・イノベーション・リミテッド ２つの潜在的ｄｎａ結合モチーフを含有する転写因子
DE60141740D1 (de) 2000-01-21 2010-05-20 Polymun Scient Immunbio Forsch Tumor- und seneszenzsmarker
EP1259618A2 (de) * 2000-03-01 2002-11-27 Incyte Genomics, Inc. Menschliche enzymmoleküle
US20020082207A1 (en) * 2000-06-07 2002-06-27 Hirst Shannon K. Compositions and methods for the therapy and diagnosis of pancreatic cancer
EP1953243B1 (de) * 2000-06-15 2012-12-26 Novartis Vaccines and Diagnostics, Inc. Polynukleotide im Zusammenhang mit Darmkrebs
WO2002020598A1 (en) * 2000-07-28 2002-03-14 Michael Andrew Mcguckin Mucin
AU2001283062A1 (en) 2000-08-02 2002-02-13 The Johns Hopkins University Endothelial cell expression patterns
EP1207202A1 (de) * 2000-11-16 2002-05-22 Mölling, Karin, Inst. für med. Virologie der Uni. Zürich Nukleinsäuremoleküle, welche für ein Protein kodieren, das mit dem Chemokinrezeptor oder anderen Mitgliedern der Chemokinrezeptorfamilie interagiert
US7189820B2 (en) 2001-05-24 2007-03-13 Human Genome Sciences, Inc. Antibodies against tumor necrosis factor delta (APRIL)
US7204982B2 (en) * 2002-07-02 2007-04-17 The Regents Of The University Of California Compositions and methods for treatment and detection of multiple cancers
GB0218468D0 (en) * 2002-08-08 2002-09-18 Univ Nottingham Trent Gastric and Colon Cancer-associated antigens
JP2007527704A (ja) * 2003-06-30 2007-10-04 ジェノバ・リミテッド 心臓血管障害に関連する分泌ポリペプチド種
BRPI0516284A (pt) 2004-09-23 2008-09-02 Genentech Inc anticorpo construìdo com cisteìna, método de selecionar anticorpos, compostos conjugados de droga-anticorpo, composição farmacêutica, método para matar ou inibir a proliferação de células de tumor, métodos de inibir a proliferação celular e o crescimento de células de tumor, artigo manufaturado e método para produzir um composto
EP2214019A1 (de) 2009-01-28 2010-08-04 Externautics S.p.A. Tumormarker und deren Verwendung
CN109152843A (zh) 2016-05-20 2019-01-04 豪夫迈·罗氏有限公司 Protac抗体缀合物及其使用方法
EP3464280B1 (de) 2016-06-06 2021-10-06 F. Hoffmann-La Roche AG Silvestrol-antikörper-arzneimittelkonjugate und verfahren zur verwendung

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0679716A1 (de) * 1993-11-12 1995-11-02 Kenichi Matsubara Genetische Signaturen

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0679716A1 (de) * 1993-11-12 1995-11-02 Kenichi Matsubara Genetische Signaturen

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
DATABASE EMBL NUCLEOTIDE SEQU 1 January 1900 (1900-01-01), XP002126820, Database accession no. AL020991 *
DATABASE EMBL NUCLEOTIDE SEQU 1 January 1900 (1900-01-01), XP002126821, Database accession no. AA554484 *
DATABASE EMBL NUCLEOTIDE SEQU 1 January 1900 (1900-01-01), XP002126822, Database accession no. AF068624 *
MÜLLER-PILLASCH, F. ET AL.: "Identification of a new tumor-associated antigen TM4SF5 and its expression in human cancer", GENE, vol. 208, no. 1, 16 February 1998 (1998-02-16), pages 25 - 30, XP004132007 *
SCHMITT, A.O. ET AL.: "Exhaustive mining of EST libraries for genes differentially expressed in normal and tumor tissue", NUCLEIC ACIDS RESEARCH, vol. 27, no. 21, 1 November 1999 (1999-11-01), pages 4251 - 4260, XP002126641 *
SURINYA, K.H. ET AL.: "Identification and Characterization of a Conserved Erythroid-specific Enhancer Located in Intron 8 of the Human 5-Aminolevulinate Synthase 2 Gene", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 273, no. 27, 3 July 1998 (1998-07-03), pages 16798 - 16809, XP002126819 *
YOKOYAMA, M. ET AL.: "Betacellulin, a member of the epidermal growth factor family, is overexpressed in human pancreatic cancer", INTERNATIONAL JOURNAL OF ONCOLOGY, vol. 7, no. 4, 1 October 1995 (1995-10-01), pages 825 - 829, XP000670300 *

Also Published As

Publication number Publication date
WO1999055858A2 (de) 1999-11-04
DE19820190A1 (de) 1999-11-04
JP2002512795A (ja) 2002-05-08
EP1076700A2 (de) 2001-02-21

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