WO1999006550A3 - 5' ESTs FOR SECRETED PROTEINS EXPRESSED IN PROSTATE - Google Patents

5' ESTs FOR SECRETED PROTEINS EXPRESSED IN PROSTATE Download PDF

Info

Publication number
WO1999006550A3
WO1999006550A3 PCT/IB1998/001232 IB9801232W WO9906550A3 WO 1999006550 A3 WO1999006550 A3 WO 1999006550A3 IB 9801232 W IB9801232 W IB 9801232W WO 9906550 A3 WO9906550 A3 WO 9906550A3
Authority
WO
WIPO (PCT)
Prior art keywords
ests
secreted proteins
prostate
proteins expressed
sequences
Prior art date
Application number
PCT/IB1998/001232
Other languages
French (fr)
Other versions
WO1999006550A2 (en
WO1999006550B1 (en
Inventor
Milne Edwards Jean-Bapti Dumas
Aymeric Duclert
Bruno Lacroix
Original Assignee
Genset Sa
Dumas Milne Edwards Jean Bapti
Aymeric Duclert
Bruno Lacroix
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Genset Sa, Dumas Milne Edwards Jean Bapti, Aymeric Duclert, Bruno Lacroix filed Critical Genset Sa
Priority to CA002296287A priority Critical patent/CA2296287A1/en
Priority to AU85551/98A priority patent/AU8555198A/en
Priority to JP2000505291A priority patent/JP2001512013A/en
Priority to EP98936590A priority patent/EP1000148A2/en
Publication of WO1999006550A2 publication Critical patent/WO1999006550A2/en
Publication of WO1999006550A3 publication Critical patent/WO1999006550A3/en
Publication of WO1999006550B1 publication Critical patent/WO1999006550B1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

Abstract

The sequences of 5' ESTs derived from mRNAs encoding secreted proteins are disclosed. The 5' ESTs may be to obtain cDNAs and genomic DNAs corresponding to the 5' ESTs. The 5' ESTs may also be used in diagnostic, forensic, gene therapy, and chromosome mapping procedures. Upstream regulatory sequences may also be obtained using the 5' ESTs. The 5' ESTs may also be used to design expression vectors and secretion vectors.
PCT/IB1998/001232 1997-08-01 1998-07-31 5' ESTs FOR SECRETED PROTEINS EXPRESSED IN PROSTATE WO1999006550A2 (en)

Priority Applications (4)

Application Number Priority Date Filing Date Title
CA002296287A CA2296287A1 (en) 1997-08-01 1998-07-31 5' ests for secreted proteins expressed in prostate
AU85551/98A AU8555198A (en) 1997-08-01 1998-07-31 5' ests for secreted proteins expressed in prostate
JP2000505291A JP2001512013A (en) 1997-08-01 1998-07-31 5'EST of secreted protein expressed in prostate
EP98936590A EP1000148A2 (en) 1997-08-01 1998-07-31 5' ESTs FOR SECRETED PROTEINS EXPRESSED IN PROSTATE

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US90514497A 1997-08-01 1997-08-01
US08/905,144 1997-08-01

Publications (3)

Publication Number Publication Date
WO1999006550A2 WO1999006550A2 (en) 1999-02-11
WO1999006550A3 true WO1999006550A3 (en) 1999-04-29
WO1999006550B1 WO1999006550B1 (en) 1999-06-03

Family

ID=25420349

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IB1998/001232 WO1999006550A2 (en) 1997-08-01 1998-07-31 5' ESTs FOR SECRETED PROTEINS EXPRESSED IN PROSTATE

Country Status (5)

Country Link
EP (1) EP1000148A2 (en)
JP (1) JP2001512013A (en)
AU (1) AU8555198A (en)
CA (1) CA2296287A1 (en)
WO (1) WO1999006550A2 (en)

Families Citing this family (83)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7241876B2 (en) 1996-01-11 2007-07-10 Corixa Corporation Compositions and methods for the therapy and diagnosis of breast cancer
US6656480B2 (en) * 1996-01-11 2003-12-02 Corixa Corporation Compositions and methods for the treatment and diagnosis of breast cancer
PL196260B1 (en) 1997-02-25 2007-12-31 Corixa Corp Polypeptide, dna molecule, host cell, fusion protein, pharmaceutical compositions and vaccines for the treatment of prostate cancer
US6261562B1 (en) 1997-02-25 2001-07-17 Corixa Corporation Compounds for immunotherapy of prostate cancer and methods for their use
US7517952B1 (en) 1997-02-25 2009-04-14 Corixa Corporation Compositions and methods for the therapy and diagnosis of prostate cancer
US6943236B2 (en) 1997-02-25 2005-09-13 Corixa Corporation Compositions and methods for the therapy and diagnosis of prostate cancer
US6613872B1 (en) 1997-02-25 2003-09-02 Corixa Corporation Compounds for immunotherapy of prostate cancer and methods for their use
US7033827B2 (en) 1997-02-25 2006-04-25 Corixa Corporation Prostate-specific polynucleotide compositions
US6465611B1 (en) 1997-02-25 2002-10-15 Corixa Corporation Compounds for immunotherapy of prostate cancer and methods for their use
US20030185830A1 (en) 1997-02-25 2003-10-02 Corixa Corporation Compositions and methods for the therapy and diagnosis of prostate cancer
US7202342B1 (en) 1999-11-12 2007-04-10 Corixa Corporation Compositions and methods for the therapy and diagnosis of prostate cancer
US6329505B1 (en) 1997-02-25 2001-12-11 Corixa Corporation Compositions and methods for therapy and diagnosis of prostate cancer
US20030027985A1 (en) 1997-06-16 2003-02-06 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
US6548633B1 (en) 1998-12-22 2003-04-15 Genset, S.A. Complementary DNA's encoding proteins with signal peptides
EP1053318A2 (en) * 1998-02-09 2000-11-22 Genset Cdnas encoding secreted proteins
AU2003262114B8 (en) * 1998-02-09 2006-08-03 Serono Genetics Institute S.A. cDNAs encoding secreted proteins
US7579160B2 (en) 1998-03-18 2009-08-25 Corixa Corporation Methods for the detection of cervical cancer
US7049063B2 (en) 1998-03-18 2006-05-23 Corixa Corporation Methods for diagnosis of lung cancer
US6737514B1 (en) 1998-12-22 2004-05-18 Corixa Corporation Compositions and methods for the therapy and diagnosis of lung cancer
US7258860B2 (en) 1998-03-18 2007-08-21 Corixa Corporation Compositions and methods for the therapy and diagnosis of lung cancer
US6660838B1 (en) 1998-03-18 2003-12-09 Corixa Corporation Compounds and methods for therapy and diagnosis of lung cancer
US6365369B1 (en) 1998-04-01 2002-04-02 Human Genome Sciences, Inc. Prostate specific secreted protein
GB9807723D0 (en) * 1998-04-08 1998-06-10 Smithkline Beecham Plc Novel compounds
DE19818620A1 (en) * 1998-04-21 1999-10-28 Metagen Gesellschaft Fuer Genomforschung Mbh New polypeptides and their nucleic acids, useful for treatment of bladder tumor and identification of therapeutic agents
US20020192751A1 (en) 1998-05-15 2002-12-19 Genentech, Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
AU3952699A (en) * 1998-05-19 1999-12-06 Compugen Ltd. Metabotropic glutamate receptor-like protein and encoding cdna
US20060052321A1 (en) 2002-04-05 2006-03-09 Raitano Arthur B Nucleic acid and corresponding protein entitled 98P4B6 useful in treatment and detection of cancer
US20030149531A1 (en) 2000-12-06 2003-08-07 Hubert Rene S. Serpentine transmembrane antigens expressed in human cancers and uses thereof
US20040141975A1 (en) 1998-06-01 2004-07-22 Raitano Arthur B. Nucleic acid and corresponding protein entitled 98P4B6 useful in treatment and detection of cancer
US6833438B1 (en) 1999-06-01 2004-12-21 Agensys, Inc. Serpentine transmembrane antigens expressed in human cancers and uses thereof
CA2328989C (en) 1998-06-01 2012-02-07 Urogenesys, Inc. Serpentine transmembrane antigens expressed in human cancers and uses thereof
AU761340B2 (en) * 1998-06-02 2003-06-05 Genentech Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
US20020172678A1 (en) 2000-06-23 2002-11-21 Napoleone Ferrara EG-VEGF nucleic acids and polypeptides and methods of use
US7264801B2 (en) 1998-08-11 2007-09-04 Genentech, Inc. EG-VEGF nucleic acids and polypeptides and method of use
AU5447899A (en) * 1998-09-03 2000-03-27 Takeda Chemical Industries Ltd. Novel protein and process for producing the same
CA2342833A1 (en) * 1998-09-17 2000-03-23 Incyte Pharmaceuticals, Inc. Human gpcr proteins
DK1626058T3 (en) * 1999-03-08 2008-02-25 Genentech Inc Tumor diagnostic compositions and methods
NZ527292A (en) 1999-03-23 2005-03-24 Genentech Inc Secreted and transmembrane polypeptides PRO1484 and nucleic acids encoding the same, with homology to an adipocyte complement-related protein
US7244827B2 (en) 2000-04-12 2007-07-17 Agensys, Inc. Nucleic acid and corresponding protein entitled 24P4C12 useful in treatment and detection of cancer
EP1792989A1 (en) * 1999-04-12 2007-06-06 Agensys, Inc. 13 Transmembrane protein expressed in prostate cancer
IL145775A0 (en) * 1999-04-12 2002-07-25 Agensys Inc 13 transmembrane protein expressed in prostate cancer
US6943235B1 (en) 1999-04-12 2005-09-13 Agensys, Inc. Transmembrane protein expressed in prostate cancer
AU3774300A (en) * 1999-06-02 2000-12-18 Genentech Inc. Secreted and transmembrane polypeptides and nucleic acids encoding the same
AU3246100A (en) * 1999-06-02 2000-12-28 Genentech Inc. Methods and compositions for inhibiting neoplastic cell growth
JP2003501072A (en) * 1999-06-07 2003-01-14 ヒューマン ジノーム サイエンシーズ， インコーポレイテッド 26 human secreted proteins
US7033780B1 (en) 1999-06-14 2006-04-25 Millennium Pharmaceuticals, Inc. Nucleic acids corresponding to TANGO 294 a gene encoding a lipase—like protein
US20030022279A1 (en) 1999-06-14 2003-01-30 Fraser Christopher C. Novel genes encoding proteins having prognostic, diagnostic, preventive, therapeutic, and other uses
JP2003521885A (en) * 1999-06-23 2003-07-22 キュラジェン コーポレイション Polynucleotides and polypeptides encoded by them
US6951738B2 (en) 1999-07-16 2005-10-04 Human Genome Sciences, Inc. Human tumor necrosis factor receptors TR13 and TR14
CA2381327A1 (en) * 1999-07-16 2001-01-25 Steven M. Ruben Human tumor necrosis factor receptors tr13 and tr14
CA2381396A1 (en) * 1999-08-11 2001-02-15 Curagen Corporation Polynucleotides and polypeptides encoded thereby
JP2003531571A (en) * 1999-09-13 2003-10-28 キュラジェン コーポレイション Novel human proteins, polynucleotides encoding them, and methods of using them
ES2371212T3 (en) * 1999-10-05 2011-12-28 Agensys, Inc. RECEPTOR COUPLED TO PROTEIN G POSITIVELY REGULATED IN PROSTATE CANCER AND USES OF THE SAME.
US7208280B2 (en) 1999-10-05 2007-04-24 Agensys, Inc. Nucleic acid and corresponding protein entitled 101P3A41 useful in treatment and detection of cancer
US6790631B1 (en) 1999-10-05 2004-09-14 Agensys, Inc. G protein-coupled receptor up-regulated in prostate cancer and uses thereof
US7361338B2 (en) 1999-10-05 2008-04-22 Agensys, Inc. Methods to inhibit growth of prostate cancer cells
EP1598671A1 (en) * 1999-10-28 2005-11-23 Agensys, Inc. Diagnosis and therapy of cancer using SGP28-related molecules
US6893818B1 (en) 1999-10-28 2005-05-17 Agensys, Inc. Gene upregulated in cancers of the prostate
US6835822B1 (en) 1999-10-28 2004-12-28 Agensys, Inc. Diagnosis and therapy of cancer using SGP28-related molecules
FR2800388A1 (en) * 1999-10-29 2001-05-04 Pf Medicament CLONING, EXPRESSION AND CHARACTERIZATION OF A GENE EXPRESSED IN TUMOR CELLS AND INVOLVED IN REGULATION OF THE IMMUNE RESPONSE
US6485938B1 (en) 1999-11-16 2002-11-26 Zymogenetics, Inc. Nucleic acid molecules that encodes human Zven1
AU1608201A (en) * 1999-11-16 2001-05-30 Zymogenetics Inc. Human zven proteins
US20020048777A1 (en) 1999-12-06 2002-04-25 Shujath Ali Method of diagnosing monitoring, staging, imaging and treating prostate cancer
US20020037513A1 (en) * 2000-03-24 2002-03-28 Rosana Kapeller-Libermann 33338, a novel human ubiquitin hydrolase-like molecule and uses thereof
KR100961345B1 (en) * 2000-06-23 2010-06-04 제넨테크, 인크. Eg-vegf nucleic acids and polypeptides and methods of use
AU2001272735A1 (en) 2000-07-18 2002-01-30 Takeda Chemical Industries Ltd. Novel physiologically active peptide and use thereof
US7048931B1 (en) 2000-11-09 2006-05-23 Corixa Corporation Compositions and methods for the therapy and diagnosis of prostate cancer
WO2002062996A1 (en) * 2001-02-02 2002-08-15 Takeda Chemical Industries, Ltd. Novel physiologically active peptide and use thereof
AUPR311601A0 (en) * 2001-02-15 2001-03-08 Adp Pharmaceutical Pty Limited Matrix gene expression in chondrogenesis
US7070584B2 (en) 2001-02-20 2006-07-04 Kci Licensing, Inc. Biocompatible wound dressing
AU2002318112B2 (en) 2001-04-10 2007-12-06 Agensys, Inc. Nucleic acids and corresponding proteins useful in the detection and treatment of various cancers
US7927597B2 (en) 2001-04-10 2011-04-19 Agensys, Inc. Methods to inhibit cell growth
WO2003022995A2 (en) 2001-09-06 2003-03-20 Agensys, Inc. Nucleic acid and corresponding protein entitled steap-1 useful in treatment and detection of cancer
US7494646B2 (en) 2001-09-06 2009-02-24 Agensys, Inc. Antibodies and molecules derived therefrom that bind to STEAP-1 proteins
WO2004016733A2 (en) 2002-08-16 2004-02-26 Agensys, Inc. Nucleic acid and corresponding protein entitled 251p5g2 useful in treatment and detection of cancer
CA2500772A1 (en) 2002-10-07 2004-04-22 Zymogenetics, Inc. Uses of human zven antagonists
CA2503346C (en) * 2002-11-27 2014-03-18 Agensys, Inc. Nucleic acid and corresponding protein entitled 24p4c12 useful in treatment and detection of cancer
KR101118340B1 (en) 2003-03-12 2012-04-12 제넨테크, 인크. Use of bv8 and/or eg-vegf to promote hematopoiesis
CA2563735C (en) 2004-04-22 2020-07-14 Agensys, Inc. Antibodies and molecules derived therefrom that bind to steap-1 proteins
FR2982860B1 (en) * 2011-11-18 2015-07-10 Ass Fr Contre Les Myopathies USE OF FIBROMODULIN AND LUMICAN TO INCREASE MUSCLE MASS
GB201511792D0 (en) * 2015-07-06 2015-08-19 Immatics Biotechnologies Gmbh Novel peptides and combination of peptides for use in immunotherapy against esopageal cancer and other cancers
CR20170579A (en) 2015-07-06 2018-05-25 Immatics Biotechnologies Gmbh NEW PEPTIDES AND COMBINATION OF PEPTIDES FOR USE IN IMMUNOTHERAPY AGAINST ESOPHAGIC CANCER AND OTHER CANCER.
WO2018184966A1 (en) 2017-04-03 2018-10-11 F. Hoffmann-La Roche Ag Antibodies binding to steap-1

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0279582A2 (en) * 1987-02-17 1988-08-24 Pharming B.V. DNA sequences to target proteins to the mammary gland for efficient secretion
EP0625572A1 (en) * 1992-09-25 1994-11-23 The Kanagawa Academy Of Science And Technology Foundation PROCESS FOR SYNTHESIZING COMPLETE-LENGTH cDNA, PROCESS FOR PRODUCING INTERMEDIATE THEREFOR, AND PROCESS FOR PRODUCING RECOMBINANT VECTOR CONTAINING COMPLETE-LENGTH cDNA
WO1996034981A2 (en) * 1995-05-02 1996-11-07 Genset Sa METHOD FOR THE SPECIFIC COUPLING OF THE CAP OF THE EXTREMITY 5' OF A FRAGMENT mRNA AND PREPARATION OF mRNA AND COMPLETE cDNA
WO1997007198A2 (en) * 1995-08-11 1997-02-27 Genetics Institute, Inc. Dna sequences and secreted proteins encoded thereby

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0279582A2 (en) * 1987-02-17 1988-08-24 Pharming B.V. DNA sequences to target proteins to the mammary gland for efficient secretion
EP0625572A1 (en) * 1992-09-25 1994-11-23 The Kanagawa Academy Of Science And Technology Foundation PROCESS FOR SYNTHESIZING COMPLETE-LENGTH cDNA, PROCESS FOR PRODUCING INTERMEDIATE THEREFOR, AND PROCESS FOR PRODUCING RECOMBINANT VECTOR CONTAINING COMPLETE-LENGTH cDNA
WO1996034981A2 (en) * 1995-05-02 1996-11-07 Genset Sa METHOD FOR THE SPECIFIC COUPLING OF THE CAP OF THE EXTREMITY 5' OF A FRAGMENT mRNA AND PREPARATION OF mRNA AND COMPLETE cDNA
WO1997007198A2 (en) * 1995-08-11 1997-02-27 Genetics Institute, Inc. Dna sequences and secreted proteins encoded thereby

Non-Patent Citations (13)

* Cited by examiner, † Cited by third party
Title
ADAMS M D ET AL: "INITIAL ASSESSMENT OF HUMAN GENE DIVERSITY AND EXPRESSION PATTERNS BASED UPON 83 MILLION NUCLEOTIDES OF CDNA SEQUENCE", NATURE, vol. 377, no. SUPPL, 28 September 1995 (1995-09-28), pages 3 - 17, XP002069461 *
CARNINCI P. ET AL.: "High-efficiency full-length cDNA cloning by biotinylated CAP trapper", GENOMICS, vol. 37, no. 3, 1 November 1996 (1996-11-01), pages 327 - 336, XP002081729 *
DATABASE EMBL - EMEST16 21 December 1996 (1996-12-21), MARRA, M. ET AL.: "ms49f10.r1 Life Tech mouse embryo 13 5dpc 10666014 Mus musculus cDNA clone 614923 5'.", XP002083641 *
DATABASE EMBL - EMEST8 4 July 1997 (1997-07-04), STRAUSBERG, R.: "nh46a08.s1 NCI_CGAP_Pr5 Homo sapiens cDNA clone IMAGE:955382 similar to gb:M21895 PROSTATE SPECIFIC ANTIGEN PRECURSOR (HUMAN).", XP002083802 *
DATABASE EMBL - EMHUM2 6 February 1997 (1997-02-06), FRANCIS, F. ET AL.: "H. sapiens PEX gene", XP002083642 *
GREENWOOD M T ET AL: "Cloning of the gene encoding human somatostatin receptor 2: sequence analysis of the 5@?-flanking promoter region", GENE, vol. 159, no. 2, 4 July 1995 (1995-07-04), pages 291-292, XP004042228 *
HEIJNE VON G.: "A new method for predicting signal sequence cleavage sites", NUCLEIC ACIDS RESEARCH, vol. 14, no. 11, 1986, pages 4683 - 4690, XP002053954 *
KATO S. ET AL.: "Construction of a human full-length cDNA bank", GENE, vol. 150, 1994, pages 243 - 250, XP002081364 *
LIN Y ET AL: "INHIBITION OF NUCLEAR TRANSLOCATION OF TRANSCRIPTION FACTOR NF-KB BY A SYNTHETIC PEPTIDE CONTAINING A CELL MEMBRANE-PERMEABLE MOTIF AND NUCLEAR LOCALIZATION SEQUENCE", JOURNAL OF BIOLOGICAL CHEMISTRY, vol. 270, no. 24, 16 June 1995 (1995-06-16), pages 14255 - 14258, XP002050723 *
LOCKHART D J ET AL: "EXPRESSION MONITORING BY HYBRIDIZATION TO HIGH-DENSITY OLIGONUCLEOTIDE ARRAYS", BIO/TECHNOLOGY, vol. 14, no. 13, December 1996 (1996-12-01), pages 1675 - 1680, XP002022521 *
LUNDWALL A ET AL: "MOLECULAR CLONING OF HUMAN PROSTATE SPECIFIC ANTIGEN CDNA", FEBS LETTERS, vol. 214, no. 2, April 1987 (1987-04-01), pages 317 - 322, XP000605372 *
TASHIRO K. ET AL.: "Signal sequence trap: a cloning strategy for secreted proteins and type I membrane proteins", SCIENCE, vol. 261, 30 July 1993 (1993-07-30), pages 600 - 603, XP000673204 *
YOKOYAMA-KOBAYASHI M. ET AL.: "A signal sequence detection system using secreted protease activity as an indicator", GENE, vol. 163, 1995, pages 193 - 196, XP002053953 *

Also Published As

Publication number Publication date
EP1000148A2 (en) 2000-05-17
CA2296287A1 (en) 1999-02-11
JP2001512013A (en) 2001-08-21
WO1999006550A2 (en) 1999-02-11
WO1999006550B1 (en) 1999-06-03
AU8555198A (en) 1999-02-22

Similar Documents

Publication Publication Date Title
WO1999006550A3 (en) 5' ESTs FOR SECRETED PROTEINS EXPRESSED IN PROSTATE
WO1999006552A3 (en) 5' ESTs FOR SECRETED PROTEINS EXPRESSED IN BRAIN
WO1999006548A3 (en) 5'ESTs FOR NON TISSUE SPECIFIC SECRETED PROTEINS
WO1999006549A3 (en) 5' ESTs FOR SECRETED PROTEINS EXPRESSED IN TESTIS AND OTHER TISSUES
WO1999053051A3 (en) 5' ests and encoded human proteins
EP1033401A3 (en) Expressed sequence tags and encoded human proteins
WO1999006554A3 (en) 5' ESTs FOR SECRETED PROTEINS EXPRESSED IN MUSCLE AND OTHER MESODERMAL TISSUES
WO1999006551A3 (en) 5' ESTs FOR SECRETED PROTEINS IDENTIFIED FROM BRAIN TISSUES
WO1999006439A3 (en) 5' ESTs FOR SECRETED PROTEINS EXPRESSED IN ENDODERM
WO1999006553A3 (en) 5' ESTs FOR SECRETED PROTEINS EXPRESSED IN VARIOUS TISSUES
WO1999031236A3 (en) EXTENDED cDNAs FOR SECRETED PROTEINS
WO1999025825A3 (en) EXTENDED cDNAs FOR SECRETED PROTEINS
WO1999040189A3 (en) Cdnas encoding secreted proteins
CA2294516A1 (en) Ikk-.beta. proteins, nucleic acids and methods
WO1999054461A3 (en) Human nucleic acid sequences of endometrium tumour tissue
CA2253238A1 (en) Novel agouti-related gene
CA2294566A1 (en) Ikk-.alpha. proteins, nucleic acids and methods
WO1999054353A3 (en) Human nucleic acid sequences of normal uterus tissue
WO1999054460A3 (en) Human nucleic acid sequences of normal bladder tissue
WO1999047655A3 (en) Human nucleic acid fragments with heightened expression in normal breast tissue
WO1999054448A3 (en) Human nucleic acid sequences, increased expression thereof in uterus myoma tissue
WO1999054446A3 (en) Human nucleic acid sequences which are overexpressed in normal pancreas tissue
EP1903111A3 (en) Extended cDNAs for secreted proteins

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A2

Designated state(s): AL AM AT AU AZ BA BB BG BR BY CA CH CN CU CZ DE DK EE ES FI GB GE GH GM HR HU ID IL IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT UA UG US UZ VN YU ZW

AL Designated countries for regional patents

Kind code of ref document: A2

Designated state(s): GH GM KE LS MW SD SZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

AK Designated states

Kind code of ref document: A3

Designated state(s): AL AM AT AU AZ BA BB BG BR BY CA CH CN CU CZ DE DK EE ES FI GB GE GH GM HR HU ID IL IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT UA UG US UZ VN YU ZW

AL Designated countries for regional patents

Kind code of ref document: A3

Designated state(s): GH GM KE LS MW SD SZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
121 Ep: the epo has been informed by wipo that ep was designated in this application
AK Designated states

Kind code of ref document: B1

Designated state(s): AL AM AT AU AZ BA BB BG BR BY CA CH CN CU CZ DE DK EE ES FI GB GE GH GM HR HU ID IL IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK SL TJ TM TR TT UA UG US UZ VN YU ZW

AL Designated countries for regional patents

Kind code of ref document: B1

Designated state(s): GH GM KE LS MW SD SZ UG ZW AM AZ BY KG KZ MD RU TJ TM AT BE CH CY DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG CI CM GA GN GW ML MR NE SN TD TG

ENP Entry into the national phase

Ref document number: 2296287

Country of ref document: CA

Ref country code: CA

Ref document number: 2296287

Kind code of ref document: A

Format of ref document f/p: F

NENP Non-entry into the national phase

Ref country code: KR

WWE Wipo information: entry into national phase

Ref document number: 85551/98

Country of ref document: AU

WWE Wipo information: entry into national phase

Ref document number: 1998936590

Country of ref document: EP

WWP Wipo information: published in national office

Ref document number: 1998936590

Country of ref document: EP

REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

WWR Wipo information: refused in national office

Ref document number: 1998936590

Country of ref document: EP

WWW Wipo information: withdrawn in national office

Ref document number: 1998936590

Country of ref document: EP