WO1999054353A3 - Human nucleic acid sequences of normal uterus tissue - Google Patents

Human nucleic acid sequences of normal uterus tissue Download PDF

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Publication number
WO1999054353A3
WO1999054353A3 PCT/DE1999/001175 DE9901175W WO9954353A3 WO 1999054353 A3 WO1999054353 A3 WO 1999054353A3 DE 9901175 W DE9901175 W DE 9901175W WO 9954353 A3 WO9954353 A3 WO 9954353A3
Authority
WO
WIPO (PCT)
Prior art keywords
nucleic acid
acid sequences
human nucleic
normal uterus
uterus tissue
Prior art date
Application number
PCT/DE1999/001175
Other languages
German (de)
French (fr)
Other versions
WO1999054353A2 (en
Inventor
Thomas Specht
Bernd Hinzmann
Armin Schmitt
Christian Pilarsky
Edgar Dahl
Andre Rosenthal
Original Assignee
Metagen Gesellschaft Fuer Genomforschung Mbh
Thomas Specht
Bernd Hinzmann
Armin Schmitt
Christian Pilarsky
Edgar Dahl
Andre Rosenthal
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Metagen Gesellschaft Fuer Genomforschung Mbh, Thomas Specht, Bernd Hinzmann, Armin Schmitt, Christian Pilarsky, Edgar Dahl, Andre Rosenthal filed Critical Metagen Gesellschaft Fuer Genomforschung Mbh
Priority to JP2000544691A priority Critical patent/JP2002512017A/en
Priority to EP99924793A priority patent/EP1071777A2/en
Publication of WO1999054353A2 publication Critical patent/WO1999054353A2/en
Publication of WO1999054353A3 publication Critical patent/WO1999054353A3/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Molecular Biology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)

Abstract

The invention relates to human nucleic acid sequences (mRNA, cDNA, genomic sequences) of normal uterus tissue, coding for genetic products or parts thereof, in addition to the use thereof. The invention also relates to the polypeptides obtained according to said sequences and to the use thereof.
PCT/DE1999/001175 1998-04-17 1999-04-15 Human nucleic acid sequences of normal uterus tissue WO1999054353A2 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
JP2000544691A JP2002512017A (en) 1998-04-17 1999-04-15 Human nucleic acid sequence from normal uterine tissue
EP99924793A EP1071777A2 (en) 1998-04-17 1999-04-15 Human nucleic acid sequences of normal uterus tissue

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19817946.4 1998-04-17
DE19817946A DE19817946A1 (en) 1998-04-17 1998-04-17 New nucleic acid sequences expressed in normal uterine tissues, and derived polypeptides, for treatment of uterine cancer and identification of therapeutic agents

Publications (2)

Publication Number Publication Date
WO1999054353A2 WO1999054353A2 (en) 1999-10-28
WO1999054353A3 true WO1999054353A3 (en) 2000-07-20

Family

ID=7865424

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/DE1999/001175 WO1999054353A2 (en) 1998-04-17 1999-04-15 Human nucleic acid sequences of normal uterus tissue

Country Status (4)

Country Link
EP (1) EP1071777A2 (en)
JP (1) JP2002512017A (en)
DE (1) DE19817946A1 (en)
WO (1) WO1999054353A2 (en)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6372473B1 (en) 1997-05-28 2002-04-16 Human Genome Sciences, Inc. Tissue plasminogen activator-like protease
AU2002301608C1 (en) * 1998-03-10 2005-08-11 Genentech, Inc. Novel PRO351 Polypeptides and Nucleic Acids Encoding Same
NZ525914A (en) * 1998-03-10 2004-03-26 Genentech Inc Novel polypeptides and nucleic acids encoding the same
US7723488B2 (en) 1998-03-27 2010-05-25 Genentech, Inc. Monoclonal antibodies to secreted and transmembrane polypeptides
PT1241186E (en) * 1998-04-22 2009-03-05 Genentech Inc Human growth arrest specific gene 6 (gas-6) and nucleic acids encoding the same
AU2224800A (en) * 1999-03-08 2000-09-28 Genentech Inc. Compositions and methods for the treatment of tumor
WO2001029084A2 (en) * 1999-10-18 2001-04-26 Lexicon Genetics Incorporated Novel human proteins and polynucleotides encoding the same
AU1174501A (en) * 1999-11-10 2001-06-06 Compugen Ltd. Chordin-like homologs
WO2001064885A1 (en) * 2000-03-02 2001-09-07 Amgen, Inc. Chordin-like-2 molecules and uses thereof
ATE292640T1 (en) 2000-05-31 2005-04-15 Genzyme Corp THERAPEUTIC COMPOUNDS AGAINST Ovarian CANCER
AU2001294943A1 (en) * 2000-10-02 2002-04-15 Bayer Corporation Nucleic acid sequences differentially expressed in cancer tissue
WO2003050307A1 (en) * 2001-12-05 2003-06-19 Genzyme Corporation Compounds for therapy and diagnosis and methods for using same
GB0216727D0 (en) 2002-07-17 2002-08-28 Univ Cambridge Tech Genes
WO2005117968A2 (en) 2004-04-14 2005-12-15 Genentech, Inc. Compositions and methods comprising an egfl7 antagonist for modulating vascular development
TWI428142B (en) 2009-05-08 2014-03-01 Genentech Inc Humanized anti-egfl7 antibodies and methods using same

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993024655A1 (en) * 1992-05-27 1993-12-09 Amersham International Plc Rna analysis
WO1999055858A2 (en) * 1998-04-28 1999-11-04 Metagen Gesellschaft Für Genomforschung Mbh Human nucleic acid sequences obtained from pancreas tumor tissue

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993024655A1 (en) * 1992-05-27 1993-12-09 Amersham International Plc Rna analysis
WO1999055858A2 (en) * 1998-04-28 1999-11-04 Metagen Gesellschaft Für Genomforschung Mbh Human nucleic acid sequences obtained from pancreas tumor tissue

Non-Patent Citations (10)

* Cited by examiner, † Cited by third party
Title
BONFIELD, J. ET AL.: "A new sequence assembly program", NUCLEIC ACIDS RESEARCH., vol. 23, 1995, pages 4992-9, XP002127627, ISSN: 0305-1048 *
CRESCENZI, E., ET AL.: "identification of differentially expressed mRNAs in normal and neoplastiic (adenocarcinoma) human endometrium", GYNECOLOGIC ONCOLOGY, vol. 63, November 1996 (1996-11-01), pages 228 - 233, XP000874036 *
FANNON M R: "Gene expression in normal and disease states - identification of therapeutic targets", TRENDS IN BIOTECHNOLOGY,GB,ELSEVIER PUBLICATIONS, CAMBRIDGE, vol. 14, no. 8, 1 August 1996 (1996-08-01), pages 294 - 298, XP004035748, ISSN: 0167-7799 *
HILLIER, L., ET AL.: "the WashU-Merck EST project - unpublished", EMBL SEQUENCE DATA LIBRARY, 7 September 1996 (1996-09-07), heidelberg, germany, XP002129529 *
HILLIER, L., ET AL.: "the WashU-Merck EST project 1997", EMBL SEQUENCE DATA LIBRARY, 11 June 1997 (1997-06-11), heidelberg, germany, XP002129531 *
HILLIER, L., ET AL.: "the WashU-Merck EST project 1997", EMBL SEQUENCE DATA LIBRARY, 14 May 1997 (1997-05-14), heidelberg, germany, XP002129530 *
JANSA,P., ET AL.: "cloning and functional characterization of PTRF, a novel protein which induces dissociation of paused ternary transcription complexes", THE EMBO JOURNAL, vol. 17, no. 10, 15 May 1998 (1998-05-15), pages 2855 - 2864, XP002129532 *
SCHMITT AO. ET AL.: "Exhaustive mining of EST libraries for genes differentially expressed in normal and tumour tissues.", NUCLEIC ACID RESEARCH, vol. 27, no. 21, November 1999 (1999-11-01), pages 4251 - 4260, XP002129533 *
SCHULER, G. D.: "Sequence mapping by electronic PCR", GENOME RESEARCH., vol. 7, 1997, pages 541 - 550, XP002127628, ISSN: 1088-9051 *
WANG, Y. AND MIKSICEK, R.J.: "characterization of estrogen receptor cDNAs of human uterus: identification of a novel PvuII polymorphism", MOLECULAR AND CELLULAR ENDOCRINOLOGY, vol. 101, 1994, pages 101 - 110, XP000874034 *

Also Published As

Publication number Publication date
WO1999054353A2 (en) 1999-10-28
DE19817946A1 (en) 1999-10-21
EP1071777A2 (en) 2001-01-31
JP2002512017A (en) 2002-04-23

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