WO1999016416A3 - Implants medicaux revetus, leur procede de preparation et leur utilisation pour la prevention de restenoses - Google Patents

Implants medicaux revetus, leur procede de preparation et leur utilisation pour la prevention de restenoses Download PDF

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Publication number
WO1999016416A3
WO1999016416A3 PCT/EP1998/006019 EP9806019W WO9916416A3 WO 1999016416 A3 WO1999016416 A3 WO 1999016416A3 EP 9806019 W EP9806019 W EP 9806019W WO 9916416 A3 WO9916416 A3 WO 9916416A3
Authority
WO
WIPO (PCT)
Prior art keywords
producing
same
coated medical
preventing restenosis
medical implants
Prior art date
Application number
PCT/EP1998/006019
Other languages
German (de)
English (en)
Other versions
WO1999016416A2 (fr
Inventor
Werner Krause
Original Assignee
Schering Ag
Werner Krause
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Ag, Werner Krause filed Critical Schering Ag
Priority to EP98952617A priority Critical patent/EP1024842A2/fr
Priority to JP2000513554A priority patent/JP2001517543A/ja
Priority to AU10251/99A priority patent/AU1025199A/en
Publication of WO1999016416A2 publication Critical patent/WO1999016416A2/fr
Publication of WO1999016416A3 publication Critical patent/WO1999016416A3/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C09—DYES; PAINTS; POLISHES; NATURAL RESINS; ADHESIVES; COMPOSITIONS NOT OTHERWISE PROVIDED FOR; APPLICATIONS OF MATERIALS NOT OTHERWISE PROVIDED FOR
    • C09D—COATING COMPOSITIONS, e.g. PAINTS, VARNISHES OR LACQUERS; FILLING PASTES; CHEMICAL PAINT OR INK REMOVERS; INKS; CORRECTING FLUIDS; WOODSTAINS; PASTES OR SOLIDS FOR COLOURING OR PRINTING; USE OF MATERIALS THEREFOR
    • C09D175/00—Coating compositions based on polyureas or polyurethanes; Coating compositions based on derivatives of such polymers
    • C09D175/04—Polyurethanes
    • C09D175/08—Polyurethanes from polyethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08—Materials for coatings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/08—Materials for coatings
    • A61L31/10—Macromolecular materials
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
    • A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L31/16—Biologically active materials, e.g. therapeutic substances
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/416—Anti-neoplastic or anti-proliferative or anti-restenosis or anti-angiogenic agents, e.g. paclitaxel, sirolimus

Abstract

L'invention concerne des agents pour la préparation d'implants médicaux revêtus libérant des principes actifs, par exemple des extenseurs, les implants ainsi préparés, leur procédé de préparation et leur utilisation pour la prévention de resténoses.
PCT/EP1998/006019 1997-09-29 1998-09-24 Implants medicaux revetus, leur procede de preparation et leur utilisation pour la prevention de restenoses WO1999016416A2 (fr)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP98952617A EP1024842A2 (fr) 1997-09-29 1998-09-24 Implants medicaux revetus, leur procede de preparation et leur utilisation pour la prevention de restenoses
JP2000513554A JP2001517543A (ja) 1997-09-29 1998-09-24 被覆医療用インプラント、その製造方法及びその再狭窄予防のための使用
AU10251/99A AU1025199A (en) 1997-09-29 1998-09-24 Coated medical implants, method for producing them, and use of the same for preventing restenosis

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19744135.1 1997-09-29
DE19744135A DE19744135C1 (de) 1997-09-29 1997-09-29 Beschichtete medizinische Implantate, Verfahren zu ihrer Herstellung und ihre Verwendung zur Restenoseprophylaxe

Publications (2)

Publication Number Publication Date
WO1999016416A2 WO1999016416A2 (fr) 1999-04-08
WO1999016416A3 true WO1999016416A3 (fr) 1999-08-05

Family

ID=7844759

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/EP1998/006019 WO1999016416A2 (fr) 1997-09-29 1998-09-24 Implants medicaux revetus, leur procede de preparation et leur utilisation pour la prevention de restenoses

Country Status (5)

Country Link
EP (1) EP1024842A2 (fr)
JP (1) JP2001517543A (fr)
AU (1) AU1025199A (fr)
DE (1) DE19744135C1 (fr)
WO (1) WO1999016416A2 (fr)

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AU756699B2 (en) 1996-12-03 2003-01-23 Sloan-Kettering Institute For Cancer Research Synthesis of epothilones, intermediates thereto, analogues and uses thereof
US6380394B1 (en) 1996-12-13 2002-04-30 The Scripps Research Institute Epothilone analogs
ATE319421T1 (de) * 1999-05-27 2006-03-15 Biocompatibles Uk Ltd Lokale arzneistoffabgabe
JP2004500918A (ja) 2000-04-11 2004-01-15 ポリゼニックス　ゲーエムベーハー ポリ−トリ−フルオロ−エトキシポリホスファゼンカバーリングおよびフィルム
EP1179353A1 (fr) * 2000-08-11 2002-02-13 B. Braun Melsungen Ag Implants antithrombotiques avec un revêtement de polyphosphazène et d'un agent actif
DE10100961B4 (de) 2001-01-11 2005-08-04 Polyzenix Gmbh Körperverträglicher Werkstoff und mit diesem Werkstoff beschichtetes Substrat für die Züchtung von Zellen und künstlichen aus Zellen aufgebauten oder gewachsenen organischen Implantaten
US9080146B2 (en) 2001-01-11 2015-07-14 Celonova Biosciences, Inc. Substrates containing polyphosphazene as matrices and substrates containing polyphosphazene with a micro-structured surface
DE10107795B4 (de) * 2001-02-13 2014-05-15 Berlex Ag Gefäßstütze mit einem Grundkörper, Verfahren zur Herstellung der Gefäßstütze, Vorrichtung zur Beschichtung der Gefäßstütze
KR20090130879A (ko) * 2001-02-16 2009-12-24 애보트 래보러토리즈 배스큘라 엔터프라이지즈 리미티드 Ｆｋ506을 포함하는 이식편
EP1270026A1 (fr) * 2001-06-22 2003-01-02 Erik Andersen Stents comprenant des analogues de vitamine D pour éviter les resténoses
EP1432380B1 (fr) 2001-08-17 2006-09-27 Polyzenix GmbH Dispositif a base de nitinol comportant un revetement polyphosphate
DE10142881A1 (de) * 2001-09-03 2003-04-03 Jomed Gmbh Implantate mit Combretastatin A-4 (CA4)
US6719540B2 (en) 2002-03-12 2004-04-13 Bristol-Myers Squibb Company C3-cyano epothilone derivatives
DE10231336A1 (de) * 2002-07-11 2004-01-22 Bayer Ag Stents
WO2004018478A2 (fr) 2002-08-23 2004-03-04 Sloan-Kettering Institute For Cancer Research Synthese d'epothilones, leurs intermediaires, leurs analogues et leurs utilisations
US7649006B2 (en) 2002-08-23 2010-01-19 Sloan-Kettering Institute For Cancer Research Synthesis of epothilones, intermediates thereto and analogues thereof
BR0317150A (pt) * 2002-12-09 2005-11-01 Novartis Ag Estabilizadores de microtúbulos em stents para o tratamento de estenose
US20050038504A1 (en) * 2003-01-22 2005-02-17 Harry Halleriet Kit for applying drug coating to a medical device in surgeon room
US8318235B2 (en) 2003-01-22 2012-11-27 Cordis Corporation Method for applying drug coating to a medical device in surgeon room
US9114162B2 (en) 2004-10-25 2015-08-25 Celonova Biosciences, Inc. Loadable polymeric particles for enhanced imaging in clinical applications and methods of preparing and using the same
US9107850B2 (en) 2004-10-25 2015-08-18 Celonova Biosciences, Inc. Color-coded and sized loadable polymeric particles for therapeutic and/or diagnostic applications and methods of preparing and using the same
US20210299056A9 (en) 2004-10-25 2021-09-30 Varian Medical Systems, Inc. Color-Coded Polymeric Particles of Predetermined Size for Therapeutic and/or Diagnostic Applications and Related Methods
US20060121511A1 (en) 2004-11-30 2006-06-08 Hyerim Lee Biomarkers and methods for determining sensitivity to microtubule-stabilizing agents
JP2010505597A (ja) 2006-10-10 2010-02-25 セロノバ バイオサイエンシーズ， インコーポレイテッド ポリホスファゼンを用いたバイオ人工心臓弁
EP2065054A1 (fr) * 2007-11-29 2009-06-03 Bayer Schering Pharma Aktiengesellschaft Combinaisons comprenant une prostaglandine et leurs utilisations

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WO1997033552A1 (fr) * 1996-03-12 1997-09-18 Pg-Txl Company, L.P. Bioprecurseurs de paclitaxel solubles dans l'eau
WO1997045105A1 (fr) * 1996-05-24 1997-12-04 Angiotech Pharmaceuticals, Inc. Compositions et methodes pour traiter ou prevenir des maladies des voies corporelles
US5716981A (en) * 1993-07-19 1998-02-10 Angiogenesis Technologies, Inc. Anti-angiogenic compositions and methods of use

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DE3524451A1 (de) * 1985-07-09 1987-03-12 Behringwerke Ag Mit ueberzuegen versehene formkoerper zur bindung von bioaffinen substanzen, verfahren zu ihrer herstellung sowie ihre verwendung
US4758435A (en) * 1986-08-11 1988-07-19 American Cyanamid Company Estradiol implant composition and method for preparation
DE19975054I2 (de) * 1987-08-08 2000-04-13 Akzo Nobel Nv Kontrazeptives Implantat
US4846844A (en) * 1987-08-31 1989-07-11 Eli Lilly And Company Antimicrobial coated implants
CH683673A5 (de) * 1991-10-01 1994-04-29 Otsuka Pharma Co Ltd Antithromboseharz, Antithromboseröhrchen, Antithrombosefilm und Antithromboseüberzug.
US5599352A (en) * 1992-03-19 1997-02-04 Medtronic, Inc. Method of making a drug eluting stent
US5342348A (en) * 1992-12-04 1994-08-30 Kaplan Aaron V Method and device for treating and enlarging body lumens
DK0797988T3 (da) * 1993-07-19 2009-05-11 Univ British Columbia Anti-angiogene præparater og fremgangsmåder til anvendelse deraf
DE4334272C2 (de) * 1993-10-07 1996-07-18 Stemberger Axel Dr Beschichtung für Biomaterial und seine Verwendung

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5716981A (en) * 1993-07-19 1998-02-10 Angiogenesis Technologies, Inc. Anti-angiogenic compositions and methods of use
WO1997033552A1 (fr) * 1996-03-12 1997-09-18 Pg-Txl Company, L.P. Bioprecurseurs de paclitaxel solubles dans l'eau
WO1997045105A1 (fr) * 1996-05-24 1997-12-04 Angiotech Pharmaceuticals, Inc. Compositions et methodes pour traiter ou prevenir des maladies des voies corporelles

Also Published As

Publication number Publication date
JP2001517543A (ja) 2001-10-09
DE19744135C1 (de) 1999-03-25
AU1025199A (en) 1999-04-23
EP1024842A2 (fr) 2000-08-09
WO1999016416A2 (fr) 1999-04-08

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