WO1998027114A3 - Antigenes de surface mammaliens et reactifs associes - Google Patents
Antigenes de surface mammaliens et reactifs associes Download PDFInfo
- Publication number
- WO1998027114A3 WO1998027114A3 PCT/US1997/023321 US9723321W WO9827114A3 WO 1998027114 A3 WO1998027114 A3 WO 1998027114A3 US 9723321 W US9723321 W US 9723321W WO 9827114 A3 WO9827114 A3 WO 9827114A3
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- cell surface
- mammalian cell
- surface antigens
- related reagents
- reagents
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Biochemistry (AREA)
- Genetics & Genomics (AREA)
- Gastroenterology & Hepatology (AREA)
- Toxicology (AREA)
- Immunology (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Zoology (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Cell Biology (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU57058/98A AU5705898A (en) | 1996-12-17 | 1997-12-16 | Mammalian cell surface antigens; related reagents |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US3360196P | 1996-12-17 | 1996-12-17 | |
US60/033,601 | 1996-12-17 |
Publications (2)
Publication Number | Publication Date |
---|---|
WO1998027114A2 WO1998027114A2 (fr) | 1998-06-25 |
WO1998027114A3 true WO1998027114A3 (fr) | 1998-10-22 |
Family
ID=21871343
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/US1997/023321 WO1998027114A2 (fr) | 1996-12-17 | 1997-12-16 | Antigenes de surface mammaliens et reactifs associes |
Country Status (2)
Country | Link |
---|---|
AU (1) | AU5705898A (fr) |
WO (1) | WO1998027114A2 (fr) |
Families Citing this family (52)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6689579B1 (en) | 1996-10-25 | 2004-02-10 | Human Genome Sciences, Inc. | Polynucleotides encoding neutrokine-α |
US6812327B1 (en) | 1996-10-25 | 2004-11-02 | Human Genome Sciences, Inc. | Neutrokine-alpha polypeptides |
CA2232743A1 (fr) * | 1997-04-02 | 1998-10-02 | Smithkline Beecham Corporation | Tl5, homologue tnf |
CA2292835A1 (fr) * | 1997-06-06 | 1998-12-10 | Regeneron Pharmaceuticals, Inc. | Membre ntn-2 de la famille des ligands du facteur de necrose tumorale (tnf) |
WO1998055620A1 (fr) * | 1997-06-06 | 1998-12-10 | Regeneron Pharmaceuticals, Inc. | Element ntn-2 de la famille des ligands du tnf |
AU9376498A (en) * | 1997-09-05 | 1999-03-22 | University Of Washington | Tumor necrosis factor family receptors and ligands, encoding nucleic acids and related binding agents |
EA200000311A1 (ru) * | 1997-09-12 | 2000-10-30 | Апотек Р Энд Д Са | Новый белок иммунной системы - кау |
JP2002503444A (ja) * | 1997-11-26 | 2002-02-05 | イーライ・リリー・アンド・カンパニー | リガンドファミリー遺伝子 |
US6297367B1 (en) | 1997-12-30 | 2001-10-02 | Chiron Corporation | Polynucleotide encoding TNFL1 |
AU2093499A (en) * | 1997-12-30 | 1999-07-19 | Chiron Corporation | Members of tnf and tnfr families |
US7488590B2 (en) | 1998-10-23 | 2009-02-10 | Amgen Inc. | Modified peptides as therapeutic agents |
GB9828628D0 (en) * | 1998-12-23 | 1999-02-17 | Glaxo Group Ltd | Novel ligand |
US7833529B1 (en) | 1999-01-07 | 2010-11-16 | Zymogenetics, Inc. | Methods for inhibiting B lymphocyte proliferation with soluble ztnf4 receptor |
US20030095967A1 (en) | 1999-01-25 | 2003-05-22 | Mackay Fabienne | BAFF, inhibitors thereof and their use in the modulation of B-cell response and treatment of autoimmune disorders |
HUP0105283A3 (en) | 1999-01-25 | 2004-08-30 | Biogen Idec Ma Inc Cambridge | Baff, inhibitors thereof and their use in the modulation of b-cell response |
US6475986B1 (en) * | 1999-02-02 | 2002-11-05 | Research Development Foundation | Uses of THANK, a TNF homologue that activates apoptosis |
JP2003526330A (ja) * | 1999-02-23 | 2003-09-09 | ヒューマン ジノーム サイエンシーズ, インコーポレイテッド | ニュートロカイン−αおよびニュートロカイン−αスプライス改変体 |
JP2002540791A (ja) * | 1999-04-05 | 2002-12-03 | インサイト・ファーマスーティカルズ・インコーポレイテッド | 免疫系の分子 |
CA2370562A1 (fr) * | 1999-04-09 | 2000-10-19 | Human Genome Sciences, Inc. | 49 proteines secretees humaines |
US20030022233A1 (en) * | 1999-04-30 | 2003-01-30 | Raymond G. Goodwin | Methods of use of the taci/taci-l interaction |
WO2000068378A1 (fr) * | 1999-05-06 | 2000-11-16 | National Jewish Medical And Research Center | Molecules d'acide nucleique, proteines et recepteurs tall-1, et procedes d'utilisation |
PL211786B1 (pl) | 1999-08-17 | 2012-06-29 | Apoxis Sa | Zastosowanie przeciwciała oraz polipeptydu |
UA74798C2 (uk) | 1999-10-06 | 2006-02-15 | Байоджен Айдек Ма Інк. | Спосіб лікування раку у ссавця за допомогою поліпептиду, що протидіє взаємодії april з його рецепторами |
CA2897626C (fr) | 2000-02-11 | 2020-03-24 | Biogen Idec Ma Inc. | Polypeptide heterologue de la famille tnf |
ATE511857T1 (de) | 2000-02-16 | 2011-06-15 | Genentech Inc | Anti-april monoklonaler antikörper und deren verwendung zur behandlung von immunerkrankungen oder krebs |
US20020086018A1 (en) | 2000-05-12 | 2002-07-04 | Theill Lars Eyde | Methods and compositions of matter concerning APRIL/G70, BCMA, BLYS/AGP-3, and TACI |
ES2609016T3 (es) | 2000-06-16 | 2017-04-18 | Human Genome Sciences, Inc. | Anticuerpos que se unen inmunoespecíficamente a BLyS |
US7220840B2 (en) | 2000-06-16 | 2007-05-22 | Human Genome Sciences, Inc. | Antibodies that immunospecifically bind to B lymphocyte stimulator protein |
AU2001288260A1 (en) * | 2000-08-15 | 2002-03-13 | Human Genome Sciences, Inc. | Neutrokine-alpha and neutrokine-alpha splice variant |
US20030091565A1 (en) | 2000-08-18 | 2003-05-15 | Beltzer James P. | Binding polypeptides and methods based thereon |
UA83458C2 (uk) | 2000-09-18 | 2008-07-25 | Байоджен Айдек Ма Інк. | Виділений поліпептид baff-r (рецептор фактора активації в-клітин сімейства tnf) |
ES2387546T3 (es) | 2001-05-11 | 2012-09-25 | Amgen Inc. | Péptidos y moléculas relacionadas que se unen a TALL-1 |
EA007275B1 (ru) | 2001-05-24 | 2006-08-25 | Займодженетикс, Инк. | Слитые белки taci-иммуноглобулина |
AR035119A1 (es) | 2001-08-16 | 2004-04-14 | Lilly Co Eli | Anticuerpos humanos antagonistas anti-htnfsf13b |
AU2004233164B2 (en) | 2003-03-28 | 2009-10-08 | Biogen Ma Inc. | Truncated BAFF receptors |
KR20060027801A (ko) | 2003-06-05 | 2006-03-28 | 제넨테크, 인크. | B 세포 장애에 대한 조합 요법 |
EP1709072A1 (fr) * | 2004-01-29 | 2006-10-11 | Genentech, Inc. | Variants du domaine extracellulaire de bcma et utilisations de ceux-ci |
BRPI0516297A (pt) | 2004-10-05 | 2008-09-02 | Genentech Inc | métodos de tratamento de vasculite e artigos de fabricação |
EP2332563A3 (fr) | 2004-10-13 | 2013-03-13 | The Washington University | Utilisation de BAFF pour traiter la sepsie |
WO2006067210A1 (fr) | 2004-12-23 | 2006-06-29 | Laboratoires Serono S.A. | Polypeptides bcma et leurs utilisations |
AU2006278227B2 (en) | 2005-08-09 | 2011-10-20 | Ares Trading S.A. | Methods for the treatment and prevention of abnormal cell proliferation using TACI-fusion molecules |
CA2618765A1 (fr) | 2005-08-09 | 2007-02-15 | Zymogenetics, Inc. | Procedes destines au traitement des malignites des lymphocytes b au moyen d'une molecule de fusion taci-ig |
US9168286B2 (en) | 2005-10-13 | 2015-10-27 | Human Genome Sciences, Inc. | Methods and compositions for use in treatment of patients with autoantibody positive disease |
MY149159A (en) | 2005-11-15 | 2013-07-31 | Hoffmann La Roche | Method for treating joint damage |
AU2006318539B2 (en) | 2005-11-23 | 2012-09-13 | Genentech, Inc. | Methods and compositions related to B cell assays |
WO2007123765A2 (fr) | 2006-03-31 | 2007-11-01 | Human Genome Sciences Inc. | NEUTROKINE-ALPHA et variant d'epissage de la neutrokine-alpha |
KR20090016707A (ko) | 2006-05-15 | 2009-02-17 | 아레스 트레이딩 에스.에이. | Taciig 융합 분자를 사용하여 자가면역 질병을 치료하는 방법 |
WO2010075249A2 (fr) | 2008-12-22 | 2010-07-01 | Genentech, Inc. | Méthode de traitement de la polyarthrite rhumatoïde avec des antagonistes de cellules b |
CN102597268B (zh) | 2009-09-03 | 2017-09-22 | 弗·哈夫曼-拉罗切有限公司 | 用于治疗、诊断和监控类风湿性关节炎的方法 |
WO2012118750A2 (fr) | 2011-02-28 | 2012-09-07 | Genentech, Inc. | Marqueurs biologiques et procédés de prédiction de réponse à des antagonistes de lymphocytes b |
US9458246B2 (en) | 2013-03-13 | 2016-10-04 | Amgen Inc. | Proteins specific for BAFF and B7RP1 |
JOP20140087B1 (ar) | 2013-03-13 | 2021-08-17 | Amgen Inc | بروتينات مخصصة ل baff و b7rp1 وإستخداماتها |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1998018921A1 (fr) * | 1996-10-25 | 1998-05-07 | Human Genome Sciences, Inc. | Neutrokine alpha |
-
1997
- 1997-12-16 WO PCT/US1997/023321 patent/WO1998027114A2/fr active Application Filing
- 1997-12-16 AU AU57058/98A patent/AU5705898A/en not_active Abandoned
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1998018921A1 (fr) * | 1996-10-25 | 1998-05-07 | Human Genome Sciences, Inc. | Neutrokine alpha |
Non-Patent Citations (2)
Title |
---|
EMBL DATABASE; EMEST6:HS307C08B; ACCESSION-NO.: D79690, 7 February 1996 (1996-02-07), XP002073749 * |
EMBL DATABASE; EMEST8:HS88288; ACCESSION-NO.: R16882, 22 April 1995 (1995-04-22), XP002073748 * |
Also Published As
Publication number | Publication date |
---|---|
WO1998027114A2 (fr) | 1998-06-25 |
AU5705898A (en) | 1998-07-15 |
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