WO1997016077A1 - Formulations a effet probiotique - Google Patents

Formulations a effet probiotique Download PDF

Info

Publication number
WO1997016077A1
WO1997016077A1 PCT/AT1996/000212 AT9600212W WO9716077A1 WO 1997016077 A1 WO1997016077 A1 WO 1997016077A1 AT 9600212 W AT9600212 W AT 9600212W WO 9716077 A1 WO9716077 A1 WO 9716077A1
Authority
WO
WIPO (PCT)
Prior art keywords
weight
formulation according
chocolate
microorganisms
lactobacillus
Prior art date
Application number
PCT/AT1996/000212
Other languages
German (de)
English (en)
Inventor
Wolfgang Kneifel
Josef Raffalt
Helmut Viernstein
Original Assignee
Ed. Haas Nährmittel Gesellschaft Mbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ed. Haas Nährmittel Gesellschaft Mbh filed Critical Ed. Haas Nährmittel Gesellschaft Mbh
Priority to EP96934180A priority Critical patent/EP0858267A1/fr
Priority to AU72655/96A priority patent/AU7265596A/en
Priority to AT0067296U priority patent/AT1759U1/de
Publication of WO1997016077A1 publication Critical patent/WO1997016077A1/fr

Links

Classifications

    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23GCOCOA; COCOA PRODUCTS, e.g. CHOCOLATE; SUBSTITUTES FOR COCOA OR COCOA PRODUCTS; CONFECTIONERY; CHEWING GUM; ICE-CREAM; PREPARATION THEREOF
    • A23G3/00Sweetmeats; Confectionery; Marzipan; Coated or filled products
    • A23G3/34Sweetmeats, confectionery or marzipan; Processes for the preparation thereof
    • A23G3/36Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds
    • A23G3/364Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds containing microorganisms or enzymes; containing paramedical or dietetical agents, e.g. vitamins
    • A23G3/366Sweetmeats, confectionery or marzipan; Processes for the preparation thereof characterised by the composition containing organic or inorganic compounds containing microorganisms or enzymes; containing paramedical or dietetical agents, e.g. vitamins containing microorganisms, enzymes
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L29/00Foods or foodstuffs containing additives; Preparation or treatment thereof
    • A23L29/065Microorganisms
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L7/00Cereal-derived products; Malt products; Preparation or treatment thereof
    • A23L7/10Cereal-derived products
    • A23L7/117Flakes or other shapes of ready-to-eat type; Semi-finished or partly-finished products therefor
    • A23L7/122Coated, filled, multilayered or hollow ready-to-eat cereals
    • AHUMAN NECESSITIES
    • A23FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23LFOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L7/00Cereal-derived products; Malt products; Preparation or treatment thereof
    • A23L7/10Cereal-derived products
    • A23L7/117Flakes or other shapes of ready-to-eat type; Semi-finished or partly-finished products therefor
    • A23L7/135Individual or non-extruded flakes, granules or shapes having similar size, e.g. breakfast cereals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • A61K35/744Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • A61K35/744Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/745Bifidobacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/66Microorganisms or materials therefrom
    • A61K35/74Bacteria
    • A61K35/741Probiotics
    • A61K35/744Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
    • A61K35/747Lactobacilli, e.g. L. acidophilus or L. brevis

Definitions

  • lactic acid bacteria encompasses a category of microorganisms which, due to their human-specific and food-technological properties, have become the focus of scientific interest in recent years and are increasingly being used in probiotic compositions.
  • a particularly preferred probiotic formulation comprises microorganisms of the Lactob species stabilized by lyophilization. acillus acidophilus and chocolate.
  • Another special muesli according to the invention contains:
  • the preparation of the probiotically active formulations according to the invention is preferably carried out in such a way that the microorganisms stabilized by lyophilization are melted into the carrier or, in the case of a liquid or pulpy consistency of the carrier, are suspended in this carrier and then the carrier containing microorganisms is mixed (preferably granulated) with the other components of the formulation and optionally processed and / or packaged.
  • the live bacterial content of Lactobacillus acidophilus was determined on Rogosa agar by plating various dilutions of the starting material. The plates were incubated for 72 hours at 37 ° C. in an anaerobic environment and the colonies obtained were counted.
  • the chocolate muesli with the probiotically active formulations according to the invention was evaluated positively by all testers. It was judged to be sufficient and pleasant tasting of chocolate and was unanimously called "chocolate muesli". A disturbing foreign taste was not found by any of the test subjects.
  • a live germ count after gastric passage which according to the present invention is at least 10 times, preferably at least 100 times, in particular at least 1000 times, higher than that of the pure, dried microorganism preparation readily achievable with the formulations according to the invention.
  • a lyophilisate from Lactobacillus acidophilus (L.acidophilus 74-2, Wiesby) with a guaranteed germ density of 1.0 x 10 11 CFU / g was in an amount of 500 g in a carrier and Hüllstoff ⁇ melt consisting of 2500 g CEBES (Laurian cocoa butter substitute, Aarhus Olie, DK) and 25 g of Ronoxan TM (Hoffmann-LaRoche, CH) were introduced and mixed at a melt temperature of 40 ° C.
  • CEBES Laurian cocoa butter substitute, Aarhus Olie, DK
  • Ronoxan TM Hoffmann-LaRoche, CH
  • Example 6 45.5 kg of dry muesli (from Haas, AT) was coated in a drawer with the formulation obtained in Example 6. This partial batch was made up to a total of 1000 kg with untreated muesli, mixed back and packed.
  • the bacterial counts of Lactobacillus were determined on Rogosa agar Plate casting process determined from various dilution levels of the starting material. The plates were incubated for 72 h at 37 ° C. in an anaerobic environment and the colonies obtained were evaluated.

Abstract

L'invention concerne une formulation à effet probiotique renfermant des micro-organismes stabilisés par lyophilisation et un substrat alimentaire, lequel permet que les micro-organismes lyophilisés traversent le suc gastrique avec un nombre de germes plus élevé. Les micro-organismes lyophilisés contenus dans le substrat sont fondus. L'invention concerne également leur utilisation comme additifs alimentaires ainsi que comme aliment, notamment du muësli, contenant cette formulation.
PCT/AT1996/000212 1995-11-02 1996-11-04 Formulations a effet probiotique WO1997016077A1 (fr)

Priority Applications (3)

Application Number Priority Date Filing Date Title
EP96934180A EP0858267A1 (fr) 1995-11-02 1996-11-04 Formulations a effet probiotique
AU72655/96A AU7265596A (en) 1995-11-02 1996-11-04 Probiotically acting formulations
AT0067296U AT1759U1 (de) 1996-11-04 1996-11-14 Probiotisch wirksame formulierungen

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
AT180995 1995-11-02
ATA1809/95 1995-11-02

Publications (1)

Publication Number Publication Date
WO1997016077A1 true WO1997016077A1 (fr) 1997-05-09

Family

ID=3521444

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/AT1996/000212 WO1997016077A1 (fr) 1995-11-02 1996-11-04 Formulations a effet probiotique

Country Status (3)

Country Link
EP (1) EP0858267A1 (fr)
AU (1) AU7265596A (fr)
WO (1) WO1997016077A1 (fr)

Cited By (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6544568B2 (en) 1998-12-15 2003-04-08 Vsl Pharmaceuticals Inc. Symbiotic functional food containing lactic acid bacteria
US6841181B2 (en) 1999-12-22 2005-01-11 Nutrinova Nutrition Specialties & Food Ingredients Gmbh Encapsulated multifunctional biologically active food component, process for its production and its use
WO2006007470A1 (fr) * 2004-07-01 2006-01-19 General Mills, Inc. Micro-organismes encapsules dans du chocolat, produits alimentaires enrobes de chocolat, et methodes de preparation
WO2006007463A1 (fr) * 2004-07-01 2006-01-19 General Mills, Inc. Cultures encapsulees dans des graisses composees, cereales de petit dejeuner recouvertes de ces graisses, et procedes d'elaboration
WO2007081981A2 (fr) * 2006-01-11 2007-07-19 Attune Foods Aliment probiotique, procede de préparation correspondant et régime alimentaire
EP0862863B2 (fr) 1997-01-09 2008-09-03 Societe Des Produits Nestle S.A. Produit céréalier contenant des probiotiques
WO2010151637A1 (fr) * 2009-06-25 2010-12-29 The Procter & Gamble Company Procédé, d'amélioration de la santé gastro-intestinale au moyen d'une combinaison d'un micro-organisme probiotique et de chocolat
US20110305796A1 (en) * 2008-09-24 2011-12-15 Florence Coulon Method and Equipment for Preparing Cheese or a Cheese Product
US8691303B2 (en) 2009-07-31 2014-04-08 The Iams Company Dusted animal food
US9173423B2 (en) 2009-07-31 2015-11-03 The Iams Company Animal food kibble with electrostatically adhered dusting
US9210945B2 (en) 2009-07-31 2015-12-15 The Iams Company Animal food having low water activity
US9771199B2 (en) 2008-07-07 2017-09-26 Mars, Incorporated Probiotic supplement, process for making, and packaging
US10104903B2 (en) 2009-07-31 2018-10-23 Mars, Incorporated Animal food and its appearance
US11154077B2 (en) 2009-07-31 2021-10-26 Mars, Incorporated Process for dusting animal food
US11304428B2 (en) 2015-02-16 2022-04-19 Mars, Incorporated Interlocking kibble
US11388914B2 (en) 2015-04-28 2022-07-19 Mars, Incorporated Process of preparing a wet pet food, wet pet food produced by the process and uses thereof

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1151669A (en) * 1967-04-11 1969-05-14 Werner Buhrdel Improvements relating to the Treatment of Freeze-Dried Bacterial Cultures
FR1584757A (fr) * 1967-06-01 1970-01-02
FR2443247A1 (fr) * 1978-12-05 1980-07-04 Nestle Sa Microbille comprenant un microorganisme et son procede de fabrication
DE3738042A1 (de) * 1986-11-12 1988-05-26 Ludwig Schokolade Gmbh Kakaohaltige zubereitung
JPH02200639A (ja) * 1989-01-31 1990-08-08 Shinfusou Seiyaku Kk 脂質被覆細菌製剤
EP0666031A2 (fr) * 1994-02-02 1995-08-09 BARILLA G. e R. F.lli - Società per Azioni Crème à base de graisse anhydre comprenant des lactobacilles viables
EP0704164A2 (fr) * 1994-09-08 1996-04-03 Fuji Oil Co., Ltd. Composition contenant des bactéries lactique

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1151669A (en) * 1967-04-11 1969-05-14 Werner Buhrdel Improvements relating to the Treatment of Freeze-Dried Bacterial Cultures
FR1584757A (fr) * 1967-06-01 1970-01-02
FR2443247A1 (fr) * 1978-12-05 1980-07-04 Nestle Sa Microbille comprenant un microorganisme et son procede de fabrication
DE3738042A1 (de) * 1986-11-12 1988-05-26 Ludwig Schokolade Gmbh Kakaohaltige zubereitung
JPH02200639A (ja) * 1989-01-31 1990-08-08 Shinfusou Seiyaku Kk 脂質被覆細菌製剤
EP0666031A2 (fr) * 1994-02-02 1995-08-09 BARILLA G. e R. F.lli - Società per Azioni Crème à base de graisse anhydre comprenant des lactobacilles viables
EP0704164A2 (fr) * 1994-09-08 1996-04-03 Fuji Oil Co., Ltd. Composition contenant des bactéries lactique

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
PATENT ABSTRACTS OF JAPAN vol. 014, no. 485 (C - 0772) 23 October 1990 (1990-10-23) *

Cited By (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0862863B2 (fr) 1997-01-09 2008-09-03 Societe Des Produits Nestle S.A. Produit céréalier contenant des probiotiques
US6544568B2 (en) 1998-12-15 2003-04-08 Vsl Pharmaceuticals Inc. Symbiotic functional food containing lactic acid bacteria
US6841181B2 (en) 1999-12-22 2005-01-11 Nutrinova Nutrition Specialties & Food Ingredients Gmbh Encapsulated multifunctional biologically active food component, process for its production and its use
WO2006007470A1 (fr) * 2004-07-01 2006-01-19 General Mills, Inc. Micro-organismes encapsules dans du chocolat, produits alimentaires enrobes de chocolat, et methodes de preparation
WO2006007463A1 (fr) * 2004-07-01 2006-01-19 General Mills, Inc. Cultures encapsulees dans des graisses composees, cereales de petit dejeuner recouvertes de ces graisses, et procedes d'elaboration
WO2007081981A2 (fr) * 2006-01-11 2007-07-19 Attune Foods Aliment probiotique, procede de préparation correspondant et régime alimentaire
WO2007081981A3 (fr) * 2006-01-11 2007-12-13 Attune Foods Aliment probiotique, procede de préparation correspondant et régime alimentaire
US9771199B2 (en) 2008-07-07 2017-09-26 Mars, Incorporated Probiotic supplement, process for making, and packaging
US10709156B2 (en) 2008-07-07 2020-07-14 Mars, Incorporated Pet supplement and methods of making
US20110305796A1 (en) * 2008-09-24 2011-12-15 Florence Coulon Method and Equipment for Preparing Cheese or a Cheese Product
WO2010151637A1 (fr) * 2009-06-25 2010-12-29 The Procter & Gamble Company Procédé, d'amélioration de la santé gastro-intestinale au moyen d'une combinaison d'un micro-organisme probiotique et de chocolat
US8691303B2 (en) 2009-07-31 2014-04-08 The Iams Company Dusted animal food
US9173423B2 (en) 2009-07-31 2015-11-03 The Iams Company Animal food kibble with electrostatically adhered dusting
US9210945B2 (en) 2009-07-31 2015-12-15 The Iams Company Animal food having low water activity
US10104903B2 (en) 2009-07-31 2018-10-23 Mars, Incorporated Animal food and its appearance
US11154077B2 (en) 2009-07-31 2021-10-26 Mars, Incorporated Process for dusting animal food
US11304428B2 (en) 2015-02-16 2022-04-19 Mars, Incorporated Interlocking kibble
US11388914B2 (en) 2015-04-28 2022-07-19 Mars, Incorporated Process of preparing a wet pet food, wet pet food produced by the process and uses thereof

Also Published As

Publication number Publication date
AU7265596A (en) 1997-05-22
EP0858267A1 (fr) 1998-08-19

Similar Documents

Publication Publication Date Title
EP1110462B1 (fr) Agent nutritionel mutifonctionnel encapsulé, biologiquement actif, son procédé de fabrication et son utilisation
DE60119515T2 (de) Probiotica für verwendung als haustierfutter
DE60133581T2 (de) Von lactobacillus casei ke01 stamm abgeleitete probiotische verbindungen
DE69833691T2 (de) BAKTERIENSTAMM DER ART LACTOBACILLUS PARACASEI, UNTERART PARACASEI, DIESEN ENTHALTENDE Zusammensetzung ZUR VERWENDUNG IN NAHRUNGSMITTELN UND PRODUKT DIESEN ENTHALTEND
DE60031372T2 (de) Verbesserte mikrobielle zubereitungen
EP2717890B1 (fr) Souches / cellules de lactobacille séchées par pulvérisation et leur utilisation contre l'helicobacter pylori
EP0858267A1 (fr) Formulations a effet probiotique
DE60011061T2 (de) Diarrhö vorbeugender lactobacillus paracasei stamm
JP6181254B1 (ja) 乳酸菌含有チョコレートおよびその製造方法
EP2228067B1 (fr) Composition probiotique et son utilisation
WO2000007571A2 (fr) Formulations renfermant des micro-organismes a effet probiotique
AT405235B (de) Probiotisch wirksame formulierung
Afzaal et al. Influence of encapsulation on the survival of probiotics in food matrix under simulated stress conditions
Kemsawasd et al. Survival of probiotics in soyoghurt plus mulberry (cv Chiang Mai 60) leaf extract during refrigerated storage and their ability to tolerate gastrointestinal transit
Mosilhey Influence of different capsule materials on the physiological properties of microencapsulated Lactobacillus acidophilus
El-Sayed et al. Ameliorate the processed cheese production by functional microcapsules loaded with mustard seed extract and Bifidobacterium bifidum
JP4119656B2 (ja) 抗酸化剤
Cinar et al. The addition of royal jelly to dairy probiotic dessert produced with predictive microbiology: Influence on physicochemical, rheological, microbial and sensorial properties
JP6739603B1 (ja) 記憶・学習能維持および/または向上用組成物及び組成物を含む食品、医薬品、飼料
JP2018023369A (ja) 乳酸菌含有チョコレートおよびその製造方法
EP3556226B1 (fr) Synbiotiques complexes destinés au développement d'un microbiote saine
EP0941669B1 (fr) Melange destine a la preparation de glaces
AT1230U1 (de) Probiotisch wirksame formulierungen
AT1759U1 (de) Probiotisch wirksame formulierungen
Buchilina Influence of Health Beneficial Monk Fruit Sweetener on Microbial and Physicochemical Characteristics of Camel Milk Yogurt

Legal Events

Date Code Title Description
AK Designated states

Kind code of ref document: A1

Designated state(s): AL AM AT AU AZ BA BB BG BR BY CA CH CN CU CZ DE DK EE ES FI GB GE HU IL IS JP KE KG KP KR KZ LC LK LR LS LT LU LV MD MG MK MN MW MX NO NZ PL PT RO RU SD SE SG SI SK TJ TM TR TT UA UG US UZ VN AM AZ BY KG KZ MD RU TJ TM

AL Designated countries for regional patents

Kind code of ref document: A1

Designated state(s): KE LS MW SD SZ UG AT BE CH DE DK ES FI FR GB GR IE IT LU MC NL PT SE BF BJ CF CG

DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
DFPE Request for preliminary examination filed prior to expiration of 19th month from priority date (pct application filed before 20040101)
121 Ep: the epo has been informed by wipo that ep was designated in this application
WWE Wipo information: entry into national phase

Ref document number: 1996934180

Country of ref document: EP

ENP Entry into the national phase

Ref country code: AT

Ref document number: 1996 9097

Date of ref document: 19970509

Kind code of ref document: A

Format of ref document f/p: F

WWE Wipo information: entry into national phase

Ref document number: 19969097

Country of ref document: AT

WWP Wipo information: published in national office

Ref document number: 1996934180

Country of ref document: EP

NENP Non-entry into the national phase

Ref country code: JP

Ref document number: 97516911

Format of ref document f/p: F

REG Reference to national code

Ref country code: DE

Ref legal event code: 8642

NENP Non-entry into the national phase

Ref country code: CA

WWW Wipo information: withdrawn in national office

Ref document number: 1996934180

Country of ref document: EP