WO1996006623A1 - Compositions antithrombotiques et non hemorragiques a base d'heparine, procede pour leur preparation et applications therapeutiques - Google Patents
Compositions antithrombotiques et non hemorragiques a base d'heparine, procede pour leur preparation et applications therapeutiques Download PDFInfo
- Publication number
- WO1996006623A1 WO1996006623A1 PCT/IB1995/000405 IB9500405W WO9606623A1 WO 1996006623 A1 WO1996006623 A1 WO 1996006623A1 IB 9500405 W IB9500405 W IB 9500405W WO 9606623 A1 WO9606623 A1 WO 9606623A1
- Authority
- WO
- WIPO (PCT)
- Prior art keywords
- heparin
- protamine
- composition according
- activity
- fractions
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/726—Glycosaminoglycans, i.e. mucopolysaccharides
- A61K31/727—Heparin; Heparan
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
Abstract
Description
Claims
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
AU24171/95A AU696954B2 (en) | 1994-08-29 | 1995-05-29 | Antithrombotic and non-hemorrhagic heparin-based compositions, process for their preparation and therapeutic applications |
JP8508580A JPH09510736A (ja) | 1994-08-29 | 1995-05-29 | ヘパリンをベースとした抗血栓性で非出血性の組成物と、その調製方法と、治療への利用 |
EP95918118A EP0779814A1 (fr) | 1994-08-29 | 1995-05-29 | Compositions antithrombotiques et non hemorragiques a base d'heparine, procede pour leur preparation et applications therapeutiques |
US08/793,314 US5922358A (en) | 1994-08-29 | 1995-05-29 | Antithrombotic and non-hemorrhagic heparin-based compositions, process for their preparation and therapeutic applications |
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9410380A FR2723847A1 (fr) | 1994-08-29 | 1994-08-29 | Compositions antithrombotiques et non hemorragiques a base d'heparine, procede pour leur preparation et applications therapeutiques. |
FR94/10380 | 1994-08-29 |
Publications (1)
Publication Number | Publication Date |
---|---|
WO1996006623A1 true WO1996006623A1 (fr) | 1996-03-07 |
Family
ID=9466541
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/IB1995/000405 WO1996006623A1 (fr) | 1994-08-29 | 1995-05-29 | Compositions antithrombotiques et non hemorragiques a base d'heparine, procede pour leur preparation et applications therapeutiques |
Country Status (9)
Country | Link |
---|---|
US (1) | US5922358A (fr) |
EP (1) | EP0779814A1 (fr) |
JP (1) | JPH09510736A (fr) |
CN (1) | CN1159162A (fr) |
AU (1) | AU696954B2 (fr) |
CA (1) | CA2198722A1 (fr) |
FR (1) | FR2723847A1 (fr) |
RU (1) | RU2151602C1 (fr) |
WO (1) | WO1996006623A1 (fr) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1551852A2 (fr) * | 2002-04-25 | 2005-07-13 | Momenta Pharmaceuticals, Inc. | Procede et produits pour administration par voie muqueuse |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6217863B1 (en) | 1995-10-30 | 2001-04-17 | Massachusetts Institute Of Technology | Rationally designed polysaccharide lyases derived from heparinase I |
IT1294797B1 (it) * | 1997-07-28 | 1999-04-15 | Fidia Advanced Biopolymers Srl | Uso dei derivati dell'acido ialuronico nella preparazione di biomateriali aventi attivita' emostatica fisica e tamponante |
US7056504B1 (en) | 1998-08-27 | 2006-06-06 | Massachusetts Institute Of Technology | Rationally designed heparinases derived from heparinase I and II |
WO2000012726A2 (fr) * | 1998-08-27 | 2000-03-09 | Massachusetts Institute Of Technology | Heparinases a conception rationnelle derivees de l'heparinase i et ii |
EP1190364A2 (fr) * | 1999-04-23 | 2002-03-27 | Massachusetts Institute Of Technology | Systeme et procede de notation de polymeres |
EP1266013B1 (fr) * | 2000-03-08 | 2014-10-15 | Massachusetts Institute Of Technology | Heparinase iii et ses utilisations |
WO2002023190A2 (fr) | 2000-09-12 | 2002-03-21 | Massachusetts Institute Of Technology | Procedes et produits apparentes a l'heparine de faible poids moleculaire |
CA2423469A1 (fr) * | 2000-10-18 | 2002-04-25 | Massachusetts Institute Of Technology | Procedes et produits associes a l'administration pulmonaires de polysaccharides |
KR100378109B1 (ko) * | 2000-10-24 | 2003-03-29 | 주식회사 메디프렉스 | 소수성 다중복합 헤파린 결합체, 그의 제조방법 및 용도 |
EP2402753A1 (fr) * | 2002-03-11 | 2012-01-04 | Momenta Pharmaceuticals, Inc. | Analyse de polysaccharides sulfatés |
CA2500661A1 (fr) * | 2002-10-01 | 2004-04-15 | Chiron Corporation | Compositions anticancereuses et contre les maladies infectieuses, et procedes d'utilisation correspondants |
WO2007140231A2 (fr) * | 2006-05-25 | 2007-12-06 | Momenta Pharmaceutical, Inc. | Composition d'héparine de bas poids moléculaire et utilisations de celle-ci |
US9139876B1 (en) | 2007-05-03 | 2015-09-22 | Momenta Pharmacueticals, Inc. | Method of analyzing a preparation of a low molecular weight heparin |
US8435795B2 (en) * | 2010-01-19 | 2013-05-07 | Momenta Pharmaceuticals, Inc. | Evaluating heparin preparations |
WO2012115952A1 (fr) | 2011-02-21 | 2012-08-30 | Momenta Pharmaceuticals, Inc. | Évaluation de préparations d'héparine |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE659943A (fr) * | 1964-03-17 | 1965-06-16 | ||
US4175182A (en) * | 1978-07-03 | 1979-11-20 | Research Corporation | Separation of high-activity heparin by affinity chromatography on supported protamine |
JPS5543123A (en) * | 1978-09-22 | 1980-03-26 | Amano Pharmaceut Co Ltd | Preparation of highly active heparin |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE15142T1 (de) * | 1981-05-21 | 1985-09-15 | Akzo Nv | Antithrombotikum auf basis von polysacchariden, verfahren zur dessen herstellung und medizinale zusammensetzungen. |
US4687765A (en) * | 1983-07-25 | 1987-08-18 | Choay S.A. | Method and composition for thrombolytic treatment |
US4800016A (en) * | 1986-11-24 | 1989-01-24 | The University Of Michigan | Extracorporeal blood de-heparinization system |
-
1994
- 1994-08-29 FR FR9410380A patent/FR2723847A1/fr active Pending
-
1995
- 1995-05-29 JP JP8508580A patent/JPH09510736A/ja not_active Withdrawn
- 1995-05-29 US US08/793,314 patent/US5922358A/en not_active Expired - Fee Related
- 1995-05-29 AU AU24171/95A patent/AU696954B2/en not_active Ceased
- 1995-05-29 CA CA002198722A patent/CA2198722A1/fr not_active Abandoned
- 1995-05-29 RU RU97104917/14A patent/RU2151602C1/ru active
- 1995-05-29 CN CN95195343A patent/CN1159162A/zh active Pending
- 1995-05-29 EP EP95918118A patent/EP0779814A1/fr not_active Withdrawn
- 1995-05-29 WO PCT/IB1995/000405 patent/WO1996006623A1/fr not_active Application Discontinuation
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE659943A (fr) * | 1964-03-17 | 1965-06-16 | ||
US4175182A (en) * | 1978-07-03 | 1979-11-20 | Research Corporation | Separation of high-activity heparin by affinity chromatography on supported protamine |
JPS5543123A (en) * | 1978-09-22 | 1980-03-26 | Amano Pharmaceut Co Ltd | Preparation of highly active heparin |
Non-Patent Citations (1)
Title |
---|
PATENT ABSTRACTS OF JAPAN vol. 4, no. 77 (C - 013) 4 June 1980 (1980-06-04) * |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP1551852A2 (fr) * | 2002-04-25 | 2005-07-13 | Momenta Pharmaceuticals, Inc. | Procede et produits pour administration par voie muqueuse |
EP1551852A4 (fr) * | 2002-04-25 | 2007-03-21 | Momenta Pharmaceuticals Inc | Procede et produits pour administration par voie muqueuse |
Also Published As
Publication number | Publication date |
---|---|
FR2723847A1 (fr) | 1996-03-01 |
RU2151602C1 (ru) | 2000-06-27 |
AU696954B2 (en) | 1998-09-24 |
EP0779814A1 (fr) | 1997-06-25 |
JPH09510736A (ja) | 1997-10-28 |
CN1159162A (zh) | 1997-09-10 |
US5922358A (en) | 1999-07-13 |
CA2198722A1 (fr) | 1996-03-07 |
AU2417195A (en) | 1996-03-22 |
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