WO1994012057A1 - Edulcorant de regime - Google Patents

Edulcorant de regime Download PDF

Info

Publication number
WO1994012057A1
WO1994012057A1 PCT/JP1993/001653 JP9301653W WO9412057A1 WO 1994012057 A1 WO1994012057 A1 WO 1994012057A1 JP 9301653 W JP9301653 W JP 9301653W WO 9412057 A1 WO9412057 A1 WO 9412057A1
Authority
WO
WIPO (PCT)
Prior art keywords
sugar
xylose
arabinose
test
sweetener
Prior art date
Application number
PCT/JP1993/001653
Other languages
English (en)
Japanese (ja)
Inventor
Toshihiko Asano
Yasumi Mori
Kiyohiko Kunugita
Tsutomu Terachi
Original Assignee
Fujisawa Pharmaceutical Co., Ltd.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fujisawa Pharmaceutical Co., Ltd. filed Critical Fujisawa Pharmaceutical Co., Ltd.
Publication of WO1994012057A1 publication Critical patent/WO1994012057A1/fr

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C13—SUGAR INDUSTRY
    • C13B—PRODUCTION OF SUCROSE; APPARATUS SPECIALLY ADAPTED THEREFOR
    • C13B50/00—Sugar products, e.g. powdered, lump or liquid sugar; Working-up of sugar
    • C13B50/002—Addition of chemicals or other foodstuffs
    • A—HUMAN NECESSITIES
    • A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
    • A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
    • A23L27/00—Spices; Flavouring agents or condiments; Artificial sweetening agents; Table salts; Dietetic salt substitutes; Preparation or treatment thereof
    • A23L27/30—Artificial sweetening agents
    • A23L27/33—Artificial sweetening agents containing sugars or derivatives
    • C—CHEMISTRY; METALLURGY
    • C13—SUGAR INDUSTRY
    • C13K—SACCHARIDES OBTAINED FROM NATURAL SOURCES OR BY HYDROLYSIS OF NATURALLY OCCURRING DISACCHARIDES, OLIGOSACCHARIDES OR POLYSACCHARIDES
    • C13K13/00—Sugars not otherwise provided for in this class
    • C—CHEMISTRY; METALLURGY
    • C13—SUGAR INDUSTRY
    • C13K—SACCHARIDES OBTAINED FROM NATURAL SOURCES OR BY HYDROLYSIS OF NATURALLY OCCURRING DISACCHARIDES, OLIGOSACCHARIDES OR POLYSACCHARIDES
    • C13K13/00—Sugars not otherwise provided for in this class
    • C13K13/002—Xylose

Definitions

  • D-xylose may be abbreviated as X y 1 and L-arabinose may be abbreviated as A ra
  • a ra L-arabinose
  • low calorie sweeteners have been invented in order to prevent obesity due to an increase in sugar intake and health problems due to the obesity (for example, Japanese Patent Application Laid-Open No. 61-205545). ).
  • sugar cannot be replaced by other sweeteners because of its sweetness, water retention, and low price, and it still maintains the top position of sweeteners.
  • the present invention relates to sugar and a dietary sweetener containing D-xylose and Z or L-arabinose in a ratio of 0.5% or more to sugar, and contains sugar and It is intended to provide a new sweetener having a dieting effect without impairing the taste of sugar.
  • the dietary sweetener containing sugar of the present invention and Xy1 and / or Ara is added to a food or the like and used as a sweetener, it does not impair the taste of the sugar and suppresses the absorption of the sugar. Therefore, it is very excellent as a low-calorie diet sweetener that suppresses an increase in blood sugar level.
  • the mixing ratio of sugar to Xy 1 and / or Ara is 0.5% or more, preferably 0.5 to 50%, more preferably 5 to 20%, 10 to sugar and sugar.
  • Xy1 and / or Ara of about 20% may be blended. 0.5% or less of Xy 1 and Z or A ra in sugar
  • the activity of Xy1 and Ara to suppress the increase in blood sugar level is not sufficient, and the activity to suppress the increase in blood sugar level reaches a plateau even when added to sugar at 50% or more.
  • Xy1 and Ara used in the present invention may be powder, liquid, crystal or granule, rice bran, wheat bran, bagasse (sugar cane squeezer), corn hull, cottonseed.
  • Xy1 and Ara crude extracts of hydrolysates such as shells may be used.
  • the mixing ratio of the two is not generally limited, but industrially, for example, when using the above-mentioned coarse sleeve, Xy1 and Ara
  • the ratio can range from 50:50 to 99: 1.
  • the sugar used in the present invention may be any of sucrose and sugar beet. These sugars are classified into honey-containing sugar, separated honey sugar according to the manufacturing method, crude sugar, refined sugar according to the degree of refining, white sugar, brown sugar, brown sugar according to the hue, and powdered sugar, cubed sugar, ice sugar, liquid sugar, etc. according to the processing form. However, any of them can be used in the present invention.
  • the diet sweetener containing sugar and XY 1 and Z or A ra in a ratio of 0.5% or more to sugar according to the present invention can be adjusted by a commonly used mixing method. It can.
  • sugar and Xy1 and / or Ara may be mechanically mixed, or Xy1 and Z or Ara may be added to a sugar solution, mixed and spray-dried.
  • the diet sweetener of the present invention may optionally contain additives.
  • additives that can be used include ordinary food additives that can be used in foods, such as flavoring agents, coloring agents, and vitamins.
  • the diet sweetener of the present invention can be used for ordinary edible sugar, that is, it can be used as a tabletop sweetener as it is as a powder or in small packages, or it can be used for cooking as a soft drink. It can also be added to liquid or solid foods such as coffee, tea, fruit juice, beef jam, jam, bean jam, jelly, confectionery, corn flakes, etc., seasonings and side foods.
  • D-xylose and L-arabinose can be used alone or in combination to prevent an increase in blood sugar levels and prevent health disorders such as diabetes, hyperlipidemia and obesity.
  • the sample is diluted with a non-toxic carrier such as a liquid carrier such as water, ethanol, ethylene glycol, or polyethylene glycol, or a solid carrier such as starch, cellulose, or polyamide powder.
  • a non-toxic carrier such as a liquid carrier such as water, ethanol, ethylene glycol, or polyethylene glycol, or a solid carrier such as starch, cellulose, or polyamide powder.
  • a non-toxic carrier such as a liquid carrier such as water, ethanol, ethylene glycol, or polyethylene glycol, or a solid carrier such as starch, cellulose, or polyamide powder.
  • a non-toxic carrier such as a liquid carrier such as water, ethanol, ethylene glycol, or polyethylene glycol, or a solid carrier such as starch, cellulose, or polyamide powder.
  • the diet sweetener of the present invention is a new diet sweetener that contains sugar and has a diet effect without impairing the taste of sugar, has high safety, and has a low sugar level to suppress an increase in blood sugar level. It is excellent as a calorie diet sweetener, and it is possible to prevent health disorders such as diabetes, hyperlipidemia and obesity by ingesting the food to which the diet sweetener of the present invention is added. Further, since the diet sweetener of the present invention does not impair the taste of sugar, it can be used as a sugar substitute sweetener in foods in which sugar is currently used as a diet sweetener.
  • Rats Male, 6-week-old, weighing about 200 g received 4 animals per group (test (Test 1), (Test 2), (Test 3), (Test 4) were used, and a total of 56 animals were used. After a 24-hour fast, a solution of D-xylose and / or L-arapinose at a predetermined concentration in a 20% aqueous solution of sugar was orally administered. Blood was collected from the tail vein at predetermined time intervals, and the blood glucose obtained by centrifuging the blood was measured using a glucose cII test (Wako). Blood collection at 0 minutes was taken before administration. The results are as shown in the table below.
  • One group dissolved 75 g of sugar in 200 ml of water on the first day.
  • 75 g of sugar and 7.5 g of xylose were dissolved in 200 ml of water, and the other group was drunk in the reverse order.
  • Blood was collected from the arm vein at predetermined time intervals, and blood glucose was measured at the Central Medical Laboratory (3-4-1, Shiroume, Mito-shi). Fasting was performed from 22:00 on the eve of drinking to 2 hours after drinking.
  • the dose of D-xylose or L-arabinose in this test corresponds to approximately 0.1 lgZkg per kg of rat body weight.
  • the diet sweetener of the present invention is a new diet sweetener containing sugar and having a diet effect without impairing the taste of sugar, and has a blood sugar level. It is useful as a low-calorie diet sweetener to suppress the rise.

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Food Science & Technology (AREA)
  • Biochemistry (AREA)
  • Nutrition Science (AREA)
  • Health & Medical Sciences (AREA)
  • Polymers & Plastics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Tea And Coffee (AREA)

Abstract

Edulcorant de régime comprenant un sucre et un D-xylose et/ou L-arabinose dans une proportion d'au moins 0,5 % par rapport au sucre.
PCT/JP1993/001653 1992-11-25 1993-11-12 Edulcorant de regime WO1994012057A1 (fr)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP4/315018 1992-11-25
JP31501892 1992-11-25

Publications (1)

Publication Number Publication Date
WO1994012057A1 true WO1994012057A1 (fr) 1994-06-09

Family

ID=18060436

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/JP1993/001653 WO1994012057A1 (fr) 1992-11-25 1993-11-12 Edulcorant de regime

Country Status (1)

Country Link
WO (1) WO1994012057A1 (fr)

Cited By (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2002040035A1 (fr) * 2000-11-15 2002-05-23 Sanwa Kosan Kabushiki Kaisha Medicament contre le diabete
WO2003094927A1 (fr) * 2002-05-07 2003-11-20 Unitika Ltd. Procede d'inhibition de l'absorption de d-glucose et inhibiteur d'absorption de d-glucose
JP2007074925A (ja) * 2005-09-12 2007-03-29 Unitika Ltd アルコール飲料及びその製造方法
JPWO2005027656A1 (ja) * 2003-09-22 2007-11-15 株式会社ユース・テクノコーポレーション 機能性甘味料
JP2008501321A (ja) * 2004-06-04 2008-01-24 ホリズン サイエンス ピーティーワイ リミテッド 天然甘味料
AU2005242204B2 (en) * 2000-11-15 2009-04-23 Makoto Fujii Remedies for diabetes mellitus
CN102648748A (zh) * 2012-03-08 2012-08-29 中德瑞生物炼制实验室(厦门)有限公司 一种润肠通便食品
CN101803669B (zh) * 2009-12-08 2013-03-06 济南圣泉唐和唐生物科技有限公司 一种冰淇淋
US8697145B2 (en) 2005-06-03 2014-04-15 Horizon Science Pty. Ltd. Substances having body mass redistribution properties
JP2014513553A (ja) * 2011-05-19 2014-06-05 シージェイ チェルジェダン コーポレイション 固化防止された甘味素材組成物及びその製造方法
US9364016B2 (en) 2006-09-19 2016-06-14 The Product Makers (Australia) Pty Ltd Extracts derived from sugar cane and a process for their manufacture
US9572852B2 (en) 2011-02-08 2017-02-21 The Product Makers (Australia) Pty Ltd Sugar extracts
JP2017538693A (ja) * 2014-11-27 2017-12-28 インキューファーム グループ エスディーエヌ ビーエイチディー ペントース及びポリフェノール化合物を含有する組成物
US10350259B2 (en) 2013-08-16 2019-07-16 The Product Makers (Australia) Pty Ltd Sugar cane derived extracts and methods of treatment
WO2022116979A1 (fr) * 2020-12-05 2022-06-09 浙江华康药业股份有限公司 Procédé de préparation de particules d'édulcorant composées de xylose et de saccharose
US11730178B2 (en) 2012-08-28 2023-08-22 Poly Gain Pte Ltd Extraction method

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS597411B2 (ja) * 1980-07-11 1984-02-18 株式会社ロツテ 植物性ソフトキヤンデイ−

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS597411B2 (ja) * 1980-07-11 1984-02-18 株式会社ロツテ 植物性ソフトキヤンデイ−

Cited By (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002154967A (ja) * 2000-11-15 2002-05-28 Makoto Fujii 糖尿病治療剤
CN100340242C (zh) * 2000-11-15 2007-10-03 三和兴产株式会社 糖尿病治疗药物
AU2005242204B2 (en) * 2000-11-15 2009-04-23 Makoto Fujii Remedies for diabetes mellitus
WO2002040035A1 (fr) * 2000-11-15 2002-05-23 Sanwa Kosan Kabushiki Kaisha Medicament contre le diabete
WO2003094927A1 (fr) * 2002-05-07 2003-11-20 Unitika Ltd. Procede d'inhibition de l'absorption de d-glucose et inhibiteur d'absorption de d-glucose
JPWO2005027656A1 (ja) * 2003-09-22 2007-11-15 株式会社ユース・テクノコーポレーション 機能性甘味料
US9161562B2 (en) 2004-06-04 2015-10-20 Horizon Science Pty Ltd Natural sweetener
JP2008501321A (ja) * 2004-06-04 2008-01-24 ホリズン サイエンス ピーティーワイ リミテッド 天然甘味料
US8138162B2 (en) 2004-06-04 2012-03-20 Horizon Science Pty Ltd. Natural sweetener
US8697145B2 (en) 2005-06-03 2014-04-15 Horizon Science Pty. Ltd. Substances having body mass redistribution properties
JP2007074925A (ja) * 2005-09-12 2007-03-29 Unitika Ltd アルコール飲料及びその製造方法
US9364016B2 (en) 2006-09-19 2016-06-14 The Product Makers (Australia) Pty Ltd Extracts derived from sugar cane and a process for their manufacture
CN101803669B (zh) * 2009-12-08 2013-03-06 济南圣泉唐和唐生物科技有限公司 一种冰淇淋
US9572852B2 (en) 2011-02-08 2017-02-21 The Product Makers (Australia) Pty Ltd Sugar extracts
US9717771B2 (en) 2011-02-08 2017-08-01 The Product Makers (Australia) Pty Ltd Sugar extract
US10226502B2 (en) 2011-02-08 2019-03-12 The Product Makers (Australia) Pty Ltd Sugar extract
JP2014513553A (ja) * 2011-05-19 2014-06-05 シージェイ チェルジェダン コーポレイション 固化防止された甘味素材組成物及びその製造方法
CN102648748A (zh) * 2012-03-08 2012-08-29 中德瑞生物炼制实验室(厦门)有限公司 一种润肠通便食品
US11730178B2 (en) 2012-08-28 2023-08-22 Poly Gain Pte Ltd Extraction method
US10350259B2 (en) 2013-08-16 2019-07-16 The Product Makers (Australia) Pty Ltd Sugar cane derived extracts and methods of treatment
JP2017538693A (ja) * 2014-11-27 2017-12-28 インキューファーム グループ エスディーエヌ ビーエイチディー ペントース及びポリフェノール化合物を含有する組成物
WO2022116979A1 (fr) * 2020-12-05 2022-06-09 浙江华康药业股份有限公司 Procédé de préparation de particules d'édulcorant composées de xylose et de saccharose

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