WO1994000094A1 - Dispositif de reconstitution - Google Patents

Dispositif de reconstitution Download PDF

Info

Publication number
WO1994000094A1
WO1994000094A1 PCT/IE1993/000035 IE9300035W WO9400094A1 WO 1994000094 A1 WO1994000094 A1 WO 1994000094A1 IE 9300035 W IE9300035 W IE 9300035W WO 9400094 A1 WO9400094 A1 WO 9400094A1
Authority
WO
WIPO (PCT)
Prior art keywords
piercing
housing
communicating
reconstitution device
vial
Prior art date
Application number
PCT/IE1993/000035
Other languages
English (en)
Inventor
Mary Therese Purcell
Oliver St. Clair Hood
Niall Anthony O'sullivan
Original Assignee
Mary Therese Purcell
Hood Oliver St Clair
Sullivan Niall Anthony O
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mary Therese Purcell, Hood Oliver St Clair, Sullivan Niall Anthony O filed Critical Mary Therese Purcell
Priority to AU43530/93A priority Critical patent/AU4353093A/en
Publication of WO1994000094A1 publication Critical patent/WO1994000094A1/fr

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2089—Containers or vials which are to be joined to each other in order to mix their contents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2006—Piercing means
    • A61J1/201—Piercing means having one piercing end
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2006—Piercing means
    • A61J1/2013—Piercing means having two piercing ends
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J1/00—Containers specially adapted for medical or pharmaceutical purposes
    • A61J1/14—Details; Accessories therefor
    • A61J1/20—Arrangements for transferring or mixing fluids, e.g. from vial to syringe
    • A61J1/2003—Accessories used in combination with means for transfer or mixing of fluids, e.g. for activating fluid flow, separating fluids, filtering fluid or venting
    • A61J1/2048—Connecting means
    • A61J1/2051—Connecting means having tap means, e.g. tap means activated by sliding

Definitions

  • the present invention relates to a reconstitution device and relates particularly though not exclusively to a device for reconstituting a drug.
  • Certain drugs are available in the form of a vial containing the drug in liquid or powder form and a flexible bag containing a diluent, and require to be reconstituted for use.
  • the traditional method of reconstitution is to use a syringe to withdraw drug from the vial and inject the drug into the bag.
  • Persons skilled in the art will be familiar with the many disadvantages of this method.
  • a communication channel is provided between the two needles and includes a valve which may be closed at the time of fitting and securing, but which may be opened by relative rotation of the vial adaptor and the bag adaptor when it is desired to reconstitute the drug.
  • the above described reconstitution device is intended to reduce wastage of expensive drugs, and in particular, it is intended that the bag and vial may be coupled together in a pharmacy for subsequent use, but the valve may be left in the closed position, and may be opened to allow reconstitution immediately before the drug is to be used, thus avoiding wastage arising from reconstitution and non-use.
  • the reconstitution device is also intended to eliminate the need for relabelling a bag after a drug has been added, because the vial which bears a label is now left permanently connected to the bag.
  • the reconstitution device is also intended to reduce exposure of medical personnel to drugs, in particular by reducing leakage and by reducing the risk of accidental scratching or pricking, and for this purpose the needles are recessed in the adaptors instead of projecting there
  • the first embodiment described above addresses many of the problems which arise with traditional methods of reconstitution, it reduces but by no means eliminates the risk of scratching or pricking.
  • the needles are recessed in the adaptors, but nevertheless there is a risk of pricking or scratching before and after use.
  • the housing comprises a. first part and a second part, which together define the hollow interior region, the first and second parts being moveable relative to each other from a non-piercing position to a piercing position for providing relative movement between the housing and the first and second piercing and communicating means for moving the first and second piercing and communicating means into the piercing and communication position.
  • the first and second parts of the housing are provided by respective tubular members moveable relative to each other with a telescoping action. This preferred embodiment is of simple construction and is easy to operate.
  • a releasable first retaining means is provided for retaining the first and second parts of the housing in the non-piercing position.
  • the first retaining means comprises a retaining lug mounted on one of the first and second parts of the housing engageable with a retaining recess formed in the other of the first and second parts of the housing.
  • the communicating means comprises a cannula extending between the first and second piercing and communicating means.
  • the first and second piercing means are formed by pointed tips on opposite ends of the cannula.
  • An abutment means may be provided on the cannula for engaging at least one of the first and second parts of the housing for moving one of the first and second piercing and communicating means into the piercing and communicating position.
  • the abutment means is provided on the cannula intermediate the first and second piercing means.
  • the abutment means comprises an abutment sleeve extending around the cannula.
  • a pair of first and second apertures are provided in the respective first and second parts of the housing to facilitate movement of the first and second piercing means from the non-piercing and non- communicating to the piercing and communicating positions, and the apertures are covered for sterility purposes by seals pierceable by the first and second piercing means.
  • seals are in the form of sealing membranes integrally formed with the housing.
  • the second retaining means is provided by a pair of inter engageable complementary formations, one of said formations being provided on one of the first and second parts of the housing, and the other being provided on the abutment means.
  • one of the first and second securing means may be releasable securing means for releasably engaging the respective first or second container.
  • the respective securing means engage the respective containers with a snap fit action.
  • the securing means on the first part of the housing engages a cap of one of the containers, and the securing means on the second part of the housing engages a tubular extension of the other container.
  • Fig. 1 is an exploded perspective view of a drug reconstituting device according to the invention
  • Fig. 2 is a perspective view of portion of the device of Fig. 1 in the direction of the arrow X of Fig. 1,
  • Fig. 4 is a cross-sectional elevational view of the device of Fig. 1, shown during use, secured to but not yet communicating with two containers.
  • Fig. 5 is a cross-sectional elevational view of the device of Fig. 1, shown during use, secured to and communicating with two containers, and
  • Fig. 6 is a cross-sectional elevational view of the device of Fig. 1, shown after use, still secured to two containers but communicating with one only of the containers.
  • a drug reconstituting device for connecting two containers, namely, a first container and a second container together for delivering a drug in the first container into a diluent in the second container.
  • the device 1 is for connecting a first container provided by a vial 2 which contains the drug in powder, liquid or syrup form with the second container provided by a bag 3 of flexible plastics material which contains the diluent.
  • a vial 2 which contains the drug in powder, liquid or syrup form
  • bag 3 of flexible plastics material which contains the diluent.
  • a first securing means comprising a vial connector 20 for connecting and securing the housing 15 to the vial 2 extends substantially axially from the outer member 18 and engages the cap 6 of the vial 2 with a snap fit action as will be described below.
  • a second securing means comprising a bag connector 25 for connecting the housing 15 to the bag 3 extends axially from the inner tubular member 19 for engaging the outlet member 9 of the bag 3 with a snap fit action as will also be described below.
  • a first protective membrane 40 integral with the first disc member 27 closes the guide bore 31 of the guide post 30 for protecting the vial piercing point 37 of the cannula 35.
  • a second protective membrane 41 formed in the second disc member 28 protects the bag piercing point 38 of the cannula 35.
  • the inner and outer members 19 and 18 are slidably moveable relative to each other from a non-piercing position illustrated in Figs. 3 and 4 to a piercing position illustrated in Fig. 5 whereby the vial and bag piercing points 37 and 38 pierce the protective membranes 40 and 41 followed by the closure membranes 7 and 11 of the vial 2 and bag 3 when the vial 2 and bag 3 are secured to the device 1.
  • a first releasable retaining means comprises a retaining lug 43 extending outwardly from the inner member 19 engageable in a retaining recess 44 in the outer member 18 for retaining the inner and outer members 18 and 19 in the non-piercing position and releasable to permit relative movement of the inner and outer members 18 and 19 to the piercing position.
  • the retaining lug 43 is carried on a resilient member 46 integrally injection moulded with the inner member 19. Provision of the retaining means allows the device 1 to be secured to the vial 2 and bag 3 without danger of the vial and bag piercing points 37 and 38 of the cannula 35 piercing the closure membranes 7 and 11 of the vial 2 and bag 3, respectively.
  • Second retaining means for retaining the vial piercing point 37 in the piercing position comprises a retaining spigot 51 extending axially from the abutment sleeve 50 and integrally formed therewith which engages a complementary retaining bore 52 formed in the guide post 30 and co-axial with the guide bore 31.
  • the vial connector 20 comprises a base 54 extending outwardly of the outer member 18 and around the first disc member. 27, and a side wall 55 extending from the base 54 and defining with the base 54 a vial engagement cavity 56 for engaging the cap 6.
  • a lip 57 extending inwardly from the side wall 55 engages against the cap 6.
  • An entry slot .58 defined by the base 54, side walls 55 and the lip 57 slidably engages the cap 6 for transversely entering the cap 6 into the engagement cavity 56, and a pair of rails 61 are provided on the base 54 to facilitate this transverse movement.
  • the rails 61 are in the form of parallel ribs on the surface of the base 54, and integrally formed with the base.
  • Portions 59 of the lip 57 extend at opposite sides into the slot 56 for engaging a neck portion 60 of the vial 2 beneath the cap 6 with a snap fit action for releasably securing the vial 2 in the vial engagement cavity 56.
  • the bag connector 25 comprises a side wall 65 extending axially of the inner member 19.
  • the side wall 65 defines with the second disc member 28 a bag engagement cavity 66 for engaging the outlet member 9 of the bag 3.
  • An entry slot 68 defined by the side walls 65 facilitates transverse entry of the outlet member 9 into the bag engagement cavity 66.
  • the first step is to secure the device 1 in position. With the inner member 19 and outer member 18 in the non-piercing position and the retaining lug 43 engaged in the retaining recess 44, the device 1 is secured to the vial 2 by entering the cap 6 of the vial 2 into the vial engagement cavity 56 through the entry slot 58 in the direction of the arrow A, see Fig. 1, until the vial 2 is securely engaged in the vial engaging cavity 56 by the snap fit action of the projecting portions 59 of the lip 57 of the neck 60 of the vial 2.
  • the device 1 is then secured to the bag 3 by engaging the outlet member 9 in the bag engagement cavity 66 through the entry slot 68 in the direction of the arrow B until the snap fit action of the side walls secures the outlet member 9 in the bag engagement cavity 66 and the lug 67 in the inside face of the resilient member 46 mates with neck 12 of the outlet member.
  • the cannula 35 is guided by the guide bore 31 in the guide post 30 as the piercing points 37 and 38 are being moved into the piercing position.
  • the cannula 35 is also guided by the sliding axial movement of the sleeve 50 which is a flush fit in the outer member 18 and which is constrained to linear axial movement by a key 80 on the inner surface of the outer member 18 and a complementary keyway 81 in the side wall of the sleeve 50.
  • Key 80 also mates with keyway 82 in the inner member 19 so that lug 43 in the inner member 19 is aligned with recess 44 in the outer member 18.
  • the piercing points 37 and 38 do not contact the drug or diluent until the moment of use, unlike the situation described in WO 86/01712. As a result the time for any contamination to take place or for any chemical reaction between piercing points 37 and 38 and drug and diluent ' is greatly reduced.
  • the sleeve 50 is located on the cannula 35 in a position so that the piercing point 37 only just penetrates the vial 2, and as a result when the vial 2
  • the piercing point 37 is at the very bottom i.e. just proud of the cap 6 of the vial 2, and all the drug drains from the vial 2.
  • the bag 3 is now ready for use. If desired the device 1 may be removed from the bag 3 and the device 1 and
  • Removal of the device 1 and vial 2 facilitates use of the bag 3. Removal is achieved by moving the inner member 19 axially into the outer member 18 into the non-piercing position shown in Fig. 6. As the inner member 19 is being moved relative
  • the retaining action of the retaining spigot 51 in the retaining bore 52 retains the cannula 35 with the vial piercing point 37 engaged in the closure membrane 7 or the cap 6 of the vial 2.
  • the bag piercing point 38 of the cannula 35 disengages from the closure membrane 11 of the outlet member 9 of the bag 3 and also disengages from the protective membrane 41 and the bag piercing point 38 is returned to the hollow interior region 29 thereby avoiding any danger of a user being pricked or scratched with the bag piercing point 38.
  • the device 1 and vial 2 remain assembled together and may be disposed.
  • the advantages of the invention are many.
  • the principal advantage of the invention is that the piercing points 37 and 38 remain enclosed before, during and after use, so that there is no risk of pricking or scratching.
  • a further advantage is that the piercing points 37 and 38 are completely sterile.
  • the housing comprises an outer and inner member 18 and 19 slidable relative to each other from a non- piercing to a piercing position, the device 1 may be assembled to a vial 2 and bag 3 without piercing of the closure membranes 7 and 11 in the vial and bag until it is desired to administer the drug so that the time for contamination is reduced.
  • the mixing of the drug and diluent can then be deferred until the drug is to be administered, and this operation can readily easily be carried out on the ward of a hospital.
  • first 16 and second 17 parts movable relative to each other, while this is preferable, it is not essential. Further, it will be appreciated that while the first 16 and second 17 parts of the housing have been described as being of cylindrical tubular construction, the first and second parts of the housing may be of any other suitable or desired construction.
  • first 37 and second 38 piercing means be provided on the same cannula 35.
  • separate cannulae may be provided and these would be communicated by a suitable communicating means.
  • any other suitable communicating means besides a cannula may be provided.
  • other suitable piercing means besides a pointed cannula may be used.
  • the securing means may be provided by connectors which would be engageable with the vial and bag respectively by axially inserting the cap of the vial and outlet member of the bag into the respective securing means.

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  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)

Abstract

Dispositif de reconstitution (1) permettant de relier l'un à l'autre deux récipients, par exemple un flacon (2) contenant un médicament, et un sac souple (3) contenant un diluant. Le dispositif est constitué d'un boîtier étanche en deux parties (16, 17) dans lequel est montée une canule (35) présentant deux pointes (37, 38). Le dispositif (1) est fixé au flacon (2) par un premier adaptateur (20) et au sac (3) par un second adaptateur (25). Ensuite, les deux parties du boîtier (16, 17) se télescopent de manière que les pointes (37, 38) percent le flacon (2) et le sac (3) et les mettent en communication l'un avec l'autre. Les pointes (37, 38) ne se trouvent à aucun moment à découvert avant, pendant ou après l'utilisation.
PCT/IE1993/000035 1992-06-22 1993-06-22 Dispositif de reconstitution WO1994000094A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
AU43530/93A AU4353093A (en) 1992-06-22 1993-06-22 A reconstitution device

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
IE922009 1992-06-22
IE922009 1992-06-22

Publications (1)

Publication Number Publication Date
WO1994000094A1 true WO1994000094A1 (fr) 1994-01-06

Family

ID=11039685

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/IE1993/000035 WO1994000094A1 (fr) 1992-06-22 1993-06-22 Dispositif de reconstitution

Country Status (2)

Country Link
AU (1) AU4353093A (fr)
WO (1) WO1994000094A1 (fr)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2005065626A1 (fr) * 2003-12-23 2005-07-21 Baxter International Inc. Dispositif reconstituant coulissant pour recipients de diluants
EP1415636A3 (fr) * 1998-09-15 2005-07-27 Baxter International Inc. Dispositif de reconstitution par coulissement pour un récipient à diluent
WO2013115728A1 (fr) * 2012-02-02 2013-08-08 Becton Dickinson Holdings Pte. Ltd. Adaptateur permettant le couplage avec un récipient médical
EP2692324A1 (fr) * 2012-08-02 2014-02-05 Becton Dickinson France Adaptateur pour couplage avec un récipient médical
CN103830107A (zh) * 2012-11-26 2014-06-04 贝克顿迪金森法国公司 用于多剂量医用容器的适配器
US9180070B2 (en) 2012-02-02 2015-11-10 Becton Dickinson Holdings Pte. Ltd. Adaptor for coupling to a medical container
USD747650S1 (en) 2013-08-05 2016-01-19 Becton Dickinson France Blocking closure for container
US9549873B2 (en) 2012-02-02 2017-01-24 Becton Dickinson Holdings Pte. Ltd. Adaptor for coupling to a medical container

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2362025A (en) * 1943-01-26 1944-11-07 Price Alison Howe Apparatus for administering blood plasma
FR2160668A1 (fr) * 1971-11-20 1973-06-29 Hoechst Ag
FR2284339A1 (fr) * 1974-09-12 1976-04-09 Philips Nv Seringue injectrice comportant un organe telescopique entre la cartouche et l'ampoule
US4227528A (en) * 1978-12-26 1980-10-14 Wardlaw Stephen C Automatic disposable hypodermic syringe
WO1986001712A1 (fr) * 1984-09-14 1986-03-27 Baxter Travenol Laboratories, Inc. Dispositif de reconstitution
DE3817101A1 (de) * 1988-05-19 1989-11-30 Axel Von Brand Vorrichtung zum ueberleiten von fluessigkeit von einem behaeltnis zu einem anderen behaeltnis

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2362025A (en) * 1943-01-26 1944-11-07 Price Alison Howe Apparatus for administering blood plasma
FR2160668A1 (fr) * 1971-11-20 1973-06-29 Hoechst Ag
FR2284339A1 (fr) * 1974-09-12 1976-04-09 Philips Nv Seringue injectrice comportant un organe telescopique entre la cartouche et l'ampoule
US4227528A (en) * 1978-12-26 1980-10-14 Wardlaw Stephen C Automatic disposable hypodermic syringe
WO1986001712A1 (fr) * 1984-09-14 1986-03-27 Baxter Travenol Laboratories, Inc. Dispositif de reconstitution
DE3817101A1 (de) * 1988-05-19 1989-11-30 Axel Von Brand Vorrichtung zum ueberleiten von fluessigkeit von einem behaeltnis zu einem anderen behaeltnis

Cited By (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1415636A3 (fr) * 1998-09-15 2005-07-27 Baxter International Inc. Dispositif de reconstitution par coulissement pour un récipient à diluent
WO2005065626A1 (fr) * 2003-12-23 2005-07-21 Baxter International Inc. Dispositif reconstituant coulissant pour recipients de diluants
CN107468520A (zh) * 2012-02-02 2017-12-15 碧迪股份有限公司 用于与医用容器相联接的适配器
AP3940A (en) * 2012-02-02 2016-12-16 Becton Dickinson Holdings Pte Ltd Adaptor for coupling with a medical container
US10966903B2 (en) 2012-02-02 2021-04-06 Becton Dickinson Holdings Pte. Ltd. Adaptor for coupling to a medical container
KR20140138668A (ko) * 2012-02-02 2014-12-04 벡톤 디킨슨 홀딩즈 피티이 엘티디. 의료용 용기와 결합하기 위한 어댑터
CN104203194A (zh) * 2012-02-02 2014-12-10 碧迪股份有限公司 用于与医用容器相联接的适配器
US20150013811A1 (en) * 2012-02-02 2015-01-15 Becton Dickinson Holdings Pte. Ltd. Adaptor for Coupling with a Medical Container
JP2015506254A (ja) * 2012-02-02 2015-03-02 ベクトン ディキンソン ホールディングス ピーティーイー リミテッド 医療用容器と接続するためのアダプタ
US9180070B2 (en) 2012-02-02 2015-11-10 Becton Dickinson Holdings Pte. Ltd. Adaptor for coupling to a medical container
US10751252B2 (en) 2012-02-02 2020-08-25 Becton Dickinson Holdings Pte. Ltd. Adaptor for coupling with a medical container
US10532005B2 (en) 2012-02-02 2020-01-14 Becton Dickinson Holdings Pte. Ltd. Adaptor for coupling to a medical container
US9549873B2 (en) 2012-02-02 2017-01-24 Becton Dickinson Holdings Pte. Ltd. Adaptor for coupling to a medical container
US9668939B2 (en) 2012-02-02 2017-06-06 Becton Dickinson Holdings Pte. Ltd. Adaptor for coupling with a medical container
CN104203194B (zh) * 2012-02-02 2017-09-08 碧迪股份有限公司 用于与医用容器相联接的适配器
WO2013115728A1 (fr) * 2012-02-02 2013-08-08 Becton Dickinson Holdings Pte. Ltd. Adaptateur permettant le couplage avec un récipient médical
KR101986869B1 (ko) * 2012-02-02 2019-06-07 벡톤 디킨슨 홀딩즈 피티이 엘티디. 의료용 용기와 결합하기 위한 어댑터
JP2018023894A (ja) * 2012-02-02 2018-02-15 ベクトン ディキンソン ホールディングス ピーティーイー リミテッド 医療用容器と接続するためのアダプタ
EP2692324A1 (fr) * 2012-08-02 2014-02-05 Becton Dickinson France Adaptateur pour couplage avec un récipient médical
CN103830107B (zh) * 2012-11-26 2018-02-13 贝克顿迪金森法国公司 用于多剂量医用容器的适配器
CN103830107A (zh) * 2012-11-26 2014-06-04 贝克顿迪金森法国公司 用于多剂量医用容器的适配器
USD747650S1 (en) 2013-08-05 2016-01-19 Becton Dickinson France Blocking closure for container

Also Published As

Publication number Publication date
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