WO1990003816A1 - Dispositif d'injection a usage unique - Google Patents

Dispositif d'injection a usage unique Download PDF

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Publication number
WO1990003816A1
WO1990003816A1 PCT/AT1989/000088 AT8900088W WO9003816A1 WO 1990003816 A1 WO1990003816 A1 WO 1990003816A1 AT 8900088 W AT8900088 W AT 8900088W WO 9003816 A1 WO9003816 A1 WO 9003816A1
Authority
WO
WIPO (PCT)
Prior art keywords
piston
injection device
piston rod
coupling elements
coupling
Prior art date
Application number
PCT/AT1989/000088
Other languages
German (de)
English (en)
Inventor
Ewald Pickhard
Original Assignee
Ewald Pickhard
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AT244088A external-priority patent/AT395535B/de
Priority claimed from AT38789A external-priority patent/ATA38789A/de
Priority claimed from AT113189A external-priority patent/ATA113189A/de
Application filed by Ewald Pickhard filed Critical Ewald Pickhard
Priority to BR898907685A priority Critical patent/BR8907685A/pt
Publication of WO1990003816A1 publication Critical patent/WO1990003816A1/fr
Priority to KR1019900701176A priority patent/KR900701341A/ko
Priority to DK58191A priority patent/DK58191D0/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/50—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for preventing re-use, or for indicating if defective, used, tampered with or unsterile
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/50—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for preventing re-use, or for indicating if defective, used, tampered with or unsterile
    • A61M5/508—Means for preventing re-use by disrupting the piston seal, e.g. by puncturing
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/50—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for preventing re-use, or for indicating if defective, used, tampered with or unsterile
    • A61M5/5066—Means for preventing re-use by disconnection of piston and piston-rod
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
    • A61M5/3205—Apparatus for removing or disposing of used needles or syringes, e.g. containers; Means for protection against accidental injuries from used needles
    • A61M5/3278—Apparatus for destroying used needles or syringes
    • A61M2005/3279—Breaking syringe nozzles or needle hubs

Definitions

  • the invention relates to an injection device for single use as described in the preamble of claim 1. .
  • the present invention is now based on the object to provide an injection device that can be used for filling a further or new Medikamen ⁇ tes after the ejection • preferably a small amount of medicament no more.
  • This object of the invention is achieved by the features specified in the characterizing part 'of the patent claim 1.
  • the surprising advantage of this solution is that after a movement of the piston rod with the piston in the direction of the syringe needle, a safety device is activated which reliably prevents the piston from moving backward away from the injection needle in the direction of the piston rod, or the syringe cylinder or the piston destroyed.
  • This solution which appears to be surprisingly simple, now makes it possible for an injection device to be destroyed at best, even with the use of brute force, but to prevent multiple use of the injection device.
  • a further development according to claim 2 is advantageous, since regardless of whether the entire amount of medication has been squeezed out of the syringe cylinder or only a small part of the medication has been squeezed out, the safety device can be activated and the pulling up of another medicament can be reliably prevented .
  • a further development according to claim 3 is also expedient. It is advantageous here that the locking ring is taken along by the piston during movements away from the injection needle, so that any medication can also be sucked into the syringe cylinder in the injection device according to the invention can. If, on the other hand, the syringe cylinder is filled with the necessary medication and the plunger with the plunger rod is adjusted only a small amount, in particular a path corresponding to a thickness of the locking ring parallel to the longitudinal axis of the syringe cylinder, in the direction of the injection needle, the triggering device is activated activated.
  • Carrying the piston is then only possible when shear forces are exerted in the direction of the injection device, but not when tensile forces are exerted, since the drive connection between the piston rod and the piston is released or is released when tensile forces are exerted.
  • a further development according to claim S is also advantageous, as a result of which a relative movement between the securing ring and the piston or piston rod is promoted without the action of an external force.
  • Snap arms move out of the locking ring and can thus be transmitted to the piston with only more compressive forces, since when a tensile force is exerted, the now free snap arms pass over the bulge of the attachment of the piston and the piston rod is thus uncoupled.
  • An embodiment according to claim 12 is also advantageous, as a result of which the support members run onto the attachment surfaces of the retaining ring and press them apart against the inner wall of the syringe barrel via the cone-shaped attachment surfaces and clamp them against one another in such a way that a further backward movement of the piston does not occur is more possible.
  • the embodiment according to claim 15 is advantageous, whereby it is ensured that the locking ring is displaced relative to the coupling device by the amount which ensures safe uncoupling of the coupling elements.
  • Another embodiment variant is disclosed in claim 16.
  • the coupling elements with a control edge distanced from the contact surface of the piston, it is surprisingly easy to carry out a lifting height defined by this control edge with the piston from an end position distanced from the outlet in the direction of the outlet and again in the direction of the distanced end position. without thereby already releasing the coupling element, the piston by the coupling elements of the support arms.
  • This lifting height can be selected by this design so that the volume change which can be achieved therewith after the application of a medicament or a solution to be injected before the application, the process of expelling e.g. with aspirated air or after the punctuation and before the injection of the drug depot, the process of aspiration, in particular blood aspiration, is also made possible.
  • an embodiment according to claim 17 is also provided, whereby a guide surface is provided on the coupling element in a surprisingly simple manner, which causes the piston rod to be guided.
  • a guide surface is provided on the coupling element in a surprisingly simple manner, which causes the piston rod to be guided.
  • further development according to claim 18 is also possible. This configuration ensures that the central guidance of the piston rod takes place in cooperation with the control strip on the coupling element with the locking ring over the entire lifting height.
  • Another embodiment variant is provided according to claim 20. This is surprisingly simple to ensure that there is no frictional connection between the control strip or the control surface of the coupling elements and the securing ring.
  • Another embodiment variant is provided according to claim 24, whereby a secure holding of the piston is guaranteed and the longitudinal mobility between the latching arms and the piston can be used in a simple manner for decoupling.
  • a further development according to patent claim 25 is also advantageous, since the latching arms spread apart on the expanding core as a result of the arresting arms and thus the coupling connection between the piston rod and the piston is released. If the opening element or the expanding core is provided with a cone angle, which brings about a self-locking effect or enables a latching in the latching arms, then a re-engagement and thus a drive connection between the piston rod and piston is prevented with a high degree of certainty. However, multiple use of the injection device is also impossible.
  • connection between the piston rod and the piston is made in a surprisingly simple manner, so that the piston can be moved in the direction of the injection needle by means of the piston rod for drawing up the medicament, but after the medication has been squeezed out, the Preventing the piston from refilling the injection device.
  • An embodiment according to claim 28 is also advantageous. This enables the clutch device to be activated due to the relative movement between the piston and the piston rod.
  • Training according to claim 30 is also possible.
  • a very compact shape for the clutch device and a further guide arrangement on the piston can be achieved with very small dimensions of the components and thus of the injection device as a whole.
  • a further development according to claim 31 is also possible. Due to the integrated arrangement of the coupling elements on the piston rod, additional components can be saved, as a result of which the assembly effort is reduced and the costs for the production of such parts are saved, while at the same time increasing the functional reliability.
  • An embodiment according to claim 33 is also advantageous, as a result of which the coupling elements are forced to remain in a position of use and, without further devices, are ensured that they come to a defined rest position after this state of constraint has been removed.
  • a further development according to claim 35 is also advantageous, as a result of which, after the coupling element has been uncoupled or relaxed, the coupling element returns to its original position and the coupling elements thereby become disengaged.
  • an embodiment according to claim 37 is also possible, as a result of which a sufficiently secure transmission of force between the piston rod and the piston is ensured during the drawing up of the medicament into the cylinder chamber, so that failure of the injection device is reliably prevented.
  • An embodiment according to claim 39 is also advantageous because it enables the coupling device to be installed in the rest position of the coupling elements and the position to be used after installation by interposing the actuator.
  • an embodiment according to claim 40 is also possible because it allows the actuator to be moved into an area in which the coupling elements can assume their rest position.
  • FIG. 1 shows an injection device in a side view, cut prior to the drawing up of a medicament into the syringe barrel
  • Figure 2 is a side view of the syringe barrel filled with medication
  • FIGS. 1 to 3 shows the injection device according to FIGS. 1 to 3 in
  • FIG. 5 shows a side view of part of an injection device with an embodiment variant of a trigger device according to the invention
  • FIG. 6 shows the side view of the injection device according to FIG. 4 after activation of the triggering device
  • P - 7 a part of an injection device with a differently designed triggering device according to the invention in side view; 8 shows the injection device according to FIG. 7 in a front view, cut along the lines VIII-VIII in FIG. 7;
  • FIG. 9 shows another triggering device for an injection device, cut in a side view and a simplified schematic illustration
  • FIG. 10 shows a part of an injection device with a trigger device according to the invention of a different design, in a side view, in section;
  • FIG. 11 shows the injection device according to FIG. 10 with a position of the piston removed from the outlet in a side view, cut;
  • FIG. 13 shows another embodiment of an injection device according to the invention with a positively actuated opening device in a side view and in a greatly simplified schematic representation
  • FIG. 14 shows another embodiment variant of an injection device according to the invention with a positively actuated opening organ, cut in a side view and a greatly simplified schematic illustration; __ ⁇
  • 15 shows an injection device designed according to the invention in a side view, in section, in a simplified schematic representation; 16 shows a part of the injection device according to FIG. 15 in a side view with the coupling elements unlocked;
  • FIG. 17 shows a side view of a variant of an actuator of an injection device according to the invention designed with an unlocking device
  • FIG. 19 shows another embodiment of an actuator of a coupling device of the injection device designed according to the invention in a side view, in section, in a highly simplified schematic illustration
  • Fig. 21 shows another embodiment of an actuator in
  • FIG. 22 shows a further embodiment of a coupling device of the injection device according to the invention in FIG.
  • FIG. 23 shows an injection device according to FIG. 22 with the coupling elements in the uncoupled position
  • 24 shows another embodiment of a coupling device according to the invention of the injection device in a side view, in section;
  • 25 shows a section through a disposable syringe according to the invention, the piston end face with the locking member being shown at a distance from the end position;
  • FIG. 26 shows a section analogous to FIG. 25 through the front section of the syringe with the latching element engaged;
  • 2B shows the front section of the disposable syringe after removal of the cannula
  • FIG. 30 shows an enlarged illustration of a second embodiment of the foremost piston section with the locking member before it enters and locks into place
  • FIG. 31 shows a section through an injection device according to the invention in side view with another embodiment for a tamper-evident device or triggering device.
  • FIG. 32 shows the side view of the injection device according to FIG. 31 after a large part of the liquid has been pressed out
  • FIG. 33 shows the injection device according to FIGS. 31 and 32 with an intermediate position of the triggering device or tamper-evident device during aspiration;
  • 34 shows a side view of part of an injection device designed according to the invention, with a triggering or tamper-evident device that allows aspiration;
  • FIG. 35 shows the injection device according to FIG. 34 in a side view when the triggering or locking device has been triggered
  • Pig- 36 a piston of the injection device according to Figure 34 in section along the lines XXXVI-XXXVI in Figure 34;
  • FIG. 37 shows a piston of the injection device according to FIGS. 34 to 36 in section along lines XXXVII-XXXVII in FIG. 35;
  • 38 is another side view of another embodiment of an injection device according to the invention with a triggering or tamper-evident device that allows aspiration.
  • the 1 shows an injection device 1, which consists of a syringe cylinder 2 and an injection needle 4 connected to it via a coupling arrangement 3.
  • the coupling arrangement 3 is arranged on a tubular outlet 5 of the syringe cylinder 2.
  • a piston rod 6 is arranged displaceably in the longitudinal direction thereof and is connected in motion to a piston B via a coupling device 7.
  • a triggering device 9 is assigned to the clutch device 7.
  • the piston 8 can consist of a rubber or plastic part or a corresponding plastic insert, on the circumference of which sealing elements, such as O-rings or rubber sleeves or the like, are arranged. With this rubber the piston 8 rests against an inner wall 10 of the syringe barrel and divides it into a cylinder chamber 11 connected to the outlet 5 and a cylinder chamber 13 assigned to an opening 12 of the syringe barrel 2.
  • the coupling elements 15 and 17 are fixed in their engaged position by a trigger device 9 designed as a locking ring 18.
  • the safety ring 18 can consist of a closed ring or also of a C-shaped ring or of two half rings. These are arranged on the sides of the coupling elements 17 opposite the projections 16, the support arms 19 and the inner wall 10 of the syringe barrel.
  • the securing ring 18 has a circular ring width that is greater than a distance 20 between the support arms 19 and the inner wall 10 of the syringe barrel less an overlap width 21 between the coupling elements 15 and 17. This ensures that as long as the retaining ring 18 is in its position in contact with the piston ⁇ , the coupling elements 17 cannot deform radially in the direction of the inner wall 10 and thus a drive connection between the piston rod 6 and the piston 8 consists.
  • the injection needle 4 with the piston rod 6, which, like the syringe cylinder 2 can be provided with handles 22 for easier operation is pulled out of the syringe cylinder 2, as can best be seen in FIG.
  • the triggering device 9 is provided. This works in such a way that when the piston rod 6 moves with the piston 8 in the direction of the outlet 5 or the injection needle 4, the retaining ring 18, which is under a biasing force directed radially outward against the inner wall 10 of the syringe cylinder 2, passes through the latter facing smooth surfaces of the support arms 19 which are arranged parallel to the associated inner side of the locking ring 18 is not taken. The piston rod 6 and the piston 8 therefore move relative to the locking ring 18 in the direction of the outlet 5 or the injection needle 4.
  • the locking ring 18 therefore remains in its position because, due to the radial preload, the holding force built up in connection with the coefficient of friction between the inner wall 10 and the locking ring 18 is greater than any adhesion that may exist between the smooth surfaces of the support arms 19 and the inner surface facing them of the locking ring 18.
  • This relative movement of the Sich ceremoniess ⁇ ring 18 against the piston 8 is not the least possible because he b away as opposed to a movement from the outlet 5 ei he d, the locking ring 18 on the piston 8 supported can and forcibly pushed in the opposite direction between the support arms 19 and the piston 8, a free space 24 is arranged which is sufficient to allow radial movement of the coupling elements 17 or the support arms 19 and projections 16 connected to them.
  • This free space 24 must have at least a length which corresponds to a length 26 of the support arms 19 running parallel to a central axis 25 of the syringe cylinder 2. If the piston has now been moved at least by the length 26 in the direction of the outlet 5, the locking ring 18 is in the free space
  • the piston rod 6 has three coupling elements 17 which are evenly distributed over the circumference and which engage between the coupling element 15 or the thickening and the piston 8.
  • FIG 5 and 6 show another embodiment variant of an injection device 1 according to the invention. Since the basic structure of the injection device is the same, the same reference numerals are used for the same parts as in the figures described above.
  • the injection device 1 again consists of a syringe cylinder 2, an outlet 5 onto which an injection needle 4 can be attached via a coupling arrangement, and a piston 8 which is movable inside the syringe cylinder 2 and which is coupled to the piston rod 6, for example via a screw connection or can also be made in one piece with this.
  • a triggering device 9 is again provided, which interacts with a tamper-evident device 27.
  • This tamper-evident device 27 consists, for example, of an approximately V-shaped spring element 28, for example a flat spring made of steel or any other material, for example also a plastic spring with metal parts which are arranged in the leg end regions and cast or otherwise connected to it.
  • the spring element 28 is held in a slot 29 in a projection 30 molded onto the piston in the region of its base.
  • the two leg ends 31 may also, as shown in the drawing, even in Rich ⁇ the inner wall 10 having angled projections 32 tung be seen ver ⁇ that ric easily ⁇ approximately perpendicular to the inner wall 10 are tet h.
  • These angled extensions can also be sanded in their frontal areas and provided with cutting edges or scratching surfaces or claws. These are supported in the position shown in FIG. 5, prepared for receiving the medicament, in which the injection device 1 is still unused, in an inner surface 33 which is marked by a
  • this medication can be dispensed to a person or an animal, for which purpose the piston 8 with the piston rod 6 is moved in the direction of the outlet 5 - arrow 39. Since there is now a corresponding distance between the piston rod 6 and the inner diameter 36 of the bore of the locking ring 34, but the locking ring 34 is prestressed in the direction of the inner wall 10, the locking ring remains in its position and it is pushed forward by the piston rod 6 the tamper-evident device 27 entrained via the slot 29 in the piston 8 moves relative to the retaining ring 34, so that the leg ends 31 or extensions 32 emerge from the retaining ring 34 and through the spring element 28 inherent spring force against the inner wall 10 of the syringe barrel 2 are pressed.
  • This Ausre.ung has the advantage that the locking ring 34 is always immediately behind the driver 38. If the securing ring in its end region facing the piston 8 is now provided with an attachment surface 44 which is inclined towards the central axis 25, the locking ring 34 would move due to the pretensioning against the inner wall 10 when the piston 8 moves against the direction indicated by the arrow 39 remain standing, and the spring element 28 entrained through the slot 29 in the piston 8 run onto these extension surfaces 44 and are additionally spread against the inner wall 10, so that a further movement of the piston against the direction of arrow 39 would be impossible. This also ensures that the piston 8 after a medicament has been drawn up and that part of the medicament has been pressed out can be moved by a maximum of the distance between the driver 38 and the piston rod body 43 or also a stop.
  • the tamper-evident device 27 can also be formed by separate S- or L-shaped brackets made of flat material or steel wire.
  • the spring elements or wire brackets can be fastened in the piston 8 by means of ultrasound embedding or gluing. It is also possible to find the sufficiency with only one spring element resting against one point of the inner wall of the syringe cylinder.
  • FIGS. 7 and 8 Another embodiment of the triggering device 9 is shown in FIGS. 7 and 8.
  • the embodiment corresponds essentially to that shown in FIGS. 5 and 6, so that again the same reference numerals are used for the same parts.
  • the driver 38 is provided with a nose or spring 45 which engages in a slot 46 of the C-shaped locking ring 34.
  • a width 47 of the spring 45 is greater than a distance between two opposite end faces 48 of the locking ring 34 in the relaxed state of the locking ring 34.
  • Spring 45 is considerably less than the friction surface between the outside of the locking ring 34 and the inner wall 10 of the syringe barrel 2, so the spring together with the piston 8 and the piston rod 6 become fixed relative to that caused by the spreading effect caused by the spring 45 move set circlip 34 and it is thus »ensured with a high degree of certainty that the tamper-evident device 27 or the spring element 28 with its extensions 32 emerges from the circlip 34 and comes to rest directly against the inner wall 10.
  • the effect of the tamper-evident device 27 then corresponds to that as has already been described with reference to FIGS. 5 and 6, in order to avoid repetition, reference is made.
  • this spring 45 can also be used in the injection device according to FIGS. 1 to 3.
  • FIG. 9 Another embodiment of a securing ring 49 is shown in FIG. 9, which can be used, for example, in connection with a triggering device 9 according to FIG.
  • the securing ring 49 differs from the embodiment shown in FIGS. 1 to 3 in that the support arms 19, which are connected to the piston rod 6, bear against a conical inner surface 50 of the securing ring 49, which is shown in FIG Tapered towards the outlet 5.
  • the inner wall 10 of the syringe barrel 2 assigned claws 51 or friction-increasing extensions.
  • the securing ring is expanded or spread in the direction of the inner wall 10 of the syringe barrel 2, so that the claws 51 can fix in the inner wall to ensure that this can not move with the piston rod 6. If the support arms 19 have overcome the narrowest point of the conical inner surface 50, the coupling elements 17 formed by snap arms can move radially freely and the desired protective effect is provided against double use of the injection device 1, as is shown in the exemplary embodiment according to FIG .1 to 3 was written, a.
  • the individual exemplary embodiments can each form independent solutions according to the invention and also the tamper-evident device 27 alone without a trigger device 9 or with any other trigger device or the trigger devices 9 each without the tamper-evident device 27 can also form independent solutions according to the invention, with which the advantages according to the invention can be achieved.
  • a coupling device 7 between the piston 8 and the piston rod 6 can also be achieved at the same time if these mutually guided parts are penetrated with radially extending bores 52, 53 engage in the coupling pins 54 connected to the spring elements 2 ⁇ . If the piston 8 moves when the piston 8 moves in the direction of the arrow 39 Pushed 38 out of the retaining ring 34, the spring element 28 snaps outward and thus simultaneously pulls the coupling pins 54 out of the bores 52 in the piston rod 6, so that when a force exerted on the piston rod is directed against the arrow 39, the force Piston rod 6 is pulled out of the piston and thus a
  • the syringe barrel is usually made of polypropylene while the plunger is made of polyethylene.
  • the embodiment according to FIGS. 5 to 7 is advantageously suitable for syringes constructed in this way.
  • the piston made of polyethylene cannot seal the surface damage formed by the tamper-evident device 27, so that the injection device is unusable.
  • the embodiments according to FIGS. 1 and 2 are advantageous.
  • FIGS Another embodiment variant of an injection device 1 according to the invention is shown in FIGS.
  • the injection device 1 again consists of a syringe cylinder 2, an outlet 5 and a piston 8 which is movable in the interior of the syringe cylinder 2 and which is coupled to the piston rod 6, for example via a coupling device 7.
  • a coupling device 7 In the area of the piston 8
  • Piston rod 6 is again provided with a triggering device 9.
  • This triggering device is formed by a, set over a An ⁇ 14 by the piston 8 distanced coupling element 15, a bead-like thickening eispielvati b and, with the Piston rod 6 connected coupling elements 17, which protrude from it in the direction of the piston 8 and are elastically deformable in the radial direction.
  • the coupling elements 15 and 17 are fixed in their engaged position by a release device 9 designed as a locking ring 18.
  • the locking ring 18 is arranged between the support arms 19 and the inner wall 10 of the syringe barrel 2.
  • a control edge 102 is arranged on the support arms 19 at a distance 100 measured axially parallel from a contact surface 101 on the piston 8.
  • a free space 24 is formed from the contact surface 101 in the direction of the piston rod 6 and the support arms 19 in the direction of the inner wall 10 of the syringe barrel 2.
  • the securing ring 18 is arranged, which has an inner diameter 103 which is larger than a diameter 104 of an enveloping circle comprising the support arms 19.
  • the support arms 19 form control strips or control surfaces 105, which are arranged concentrically to the central axis 25, relative to the locking ring 18 over the distance 100.
  • the cross-sectional area of the free space 24 of the control edge 102 is enlarged in the direction of the piston rod 6 and the central axis.
  • a length 107 of the free space 24 is greater than the distance 100, zuzüg ⁇ Lich a length 108 of the retaining ring 18.
  • ann k but also the length 107 of the free space 24 nor a Ü he b d eckungsdorf 109 of the coupling device 7 is increased. be trained.
  • a lifting height 110 is fixed, up to which the triggering device 9 is not effective. If the injection device 1 is now prepared for dispensing a medication 23, as can be seen better in FIG. 6, by moving the piston 8 in the direction of the outlet 5 by a lifting height 110, for example air 111 drawn in from the injection device 1 be removed. If the lifting height 110 is chosen to be smaller than the distance 100, the triggering device 9 does not take effect and it is thus possible, after the injection needle 4 has been set by moving the piston 8 in the direction of the arrow 112 around the lifting height 110, to perform an aspiration process, which ultimately occurs with everyone Injection should be carried out. If, subsequently, as already described in FIG.
  • the piston 8 is moved by more than the distance 100 in the opposite direction to the arrow 112 for the application of the medicament 23, the securing ring 18 is received by the free space 24, as corresponds to the dash-dotted line .
  • This allows the radially elastic support arms 19 to spring open and the coupling element 15 arranged on the piston 8 is released.
  • the piston 8 with the support arms 19 which are supported on the front-side contact surface 101 can thus only be moved in the direction of the outlet 5.
  • the piston 8 can no longer be taken along in the direction of the arrow 112, which effectively prevents the injection device from being refilled.
  • the change in volume required for expelling air 111 and for sucking in blood, for example, for performing the aspiration can be determined by the appropriate choice of distance 100 for control edge 102.
  • the suction volume can be adapted exactly to the volume of the needle channel 113 and that of the outlet opening 114.
  • the processes can already be observed from the needle opening 115 facing the piston 8, as a result of which the lifting height 110 can also be kept small.
  • FIG. 7 A further variant of a coupling device 7 is shown in FIG. The same reference numerals are used again for components already shown in FIGS. 1 to 11.
  • a coupling element 15 is arranged on the piston 8 via an extension 14.
  • the coupling elements 15, 116 are surrounded by half-shell-shaped connecting elements 117, an outer diameter 118 of the connecting elements 117 being slightly smaller than an inner diameter of the securing ring 18 concentrically encompassing the connecting elements 117.
  • the outer diameter of the securing ring 18 is thus chosen that a relative movement between syringe barrel 2 and circlip 18 difficult due to higher pressing force or friction force, but between t circlip 18 and connecting element 117 by choice of
  • Diameter as described above, is easy. As a result, when the piston rod 6 moves axially in the direction of an arrow 119, the relative movement between the connecting element 117 and the securing ring 18 disengages the latter after a stroke 120 has been covered, as a result of which the divided connecting elements 117 are lost due to the outer circumference being omitted by the Lock ring 18 fall off and release the coupling elements 15, 116.
  • the choice of the axially parallel lengths of the securing ring 18 and the connecting elements 117 makes it possible to precisely predetermine the volume change possible by means of a piston movement until a decoupling process occurs. Therefore, this embodiment is also suitable for the venting of the syringe to be carried out on the occasion of the administration of a medicament or a solution by injection, as well as for a possibly required aspiration.
  • knobs 121 projecting over the inner wall 10 of the syringe cylinder 2 can limit the movement of the piston 8 via the securing ring 18.
  • These knobs 121 can, as is currently the case with commercially available disposable syringes, be formed by deformations of the syringe cylinder, which also prevented the plunger from falling out.
  • control bar or the control surface 105 does not have to extend over the entire length of the distance 100 of the coupling element 17 or support arm 19, but can, as is schematically indicated in FIG. 6 by dashed lines, only by lugs 122 extending over part of the distance 100 may be formed.
  • the lifting height 1.10 in the present exemplary embodiment was set to this extent for the sake of clarity, but it could, for example, have a maximum size delimited by a dash-dotted line 123.
  • a radial movement of the coupling elements of the support arms 19 by the locking ring 18 would still be prevented even with a movement extending up to the line 123 and acting in the direction of the arrow 112, and thus a movement of the piston 8 in the direction of the arrow 112 would be possible .
  • an alternative embodiment is a tamper-preventing apparatus shown after the invention abandonedbil ⁇ d eten injection device 1 two hundred and first
  • the injection device tion consists of a syringe cylinder 2, an outlet 5, a piston 8 arranged in the syringe cylinder 2, which separates a cylinder chamber 11 for receiving a solution 221 from a cylinder chamber 13.
  • the piston 8 is provided with a guide projection 239, which has a projection 241 separated by a groove-shaped recess 240. This projection 241 engages around latching arms 242, which are formed on the piston rod 6 or are connected to it, and in doing so snap into the recess 240 with locking lugs 243.
  • the locking lugs 243 are provided with conically widening support surfaces against the piston 8, which are supported on a support surface 244 widening conically against the piston 8 by the groove-shaped recess 240. While part of this conical support surface, which can for example run at a cone angle 245 of approximately 45 degrees, is formed by the groove-shaped recess 240, while a further support surface part 246 is arranged on an expansion ring 247. In principle, this support surface 244 forms an inclined plane along which the locking arms 242 slide outward when the piston rod 6 is subjected to a force in a direction indicated by the arrow 248 in a position indicated by dashed lines.
  • Support piston 8 ' this can be moved freely in the direction of arrow 248 relative to the syringe barrel 2. If, however, the user of such an injection device 1 tries to use the piston 8 a second time to draw up another solution 221, he pulls the locking arms 242, which are locked in the expansion ring 247, with the expansion ring from the piston 8 via the piston rod 6 from.
  • the expansion ring 247 is guided with sufficient radial play on the guide projection 239, so that any adhesive force that may be present between the expansion ring 247 and the guide projection 239 is not sufficient to retract the piston 8 against the direction of the arrow 248 and at the same time to apply such a high force that a solution 221 can be sucked up.
  • FIG. 14 also shows an injection device 1 according to the invention, which comprises a syringe cylinder 2 and a piston 8, which divides the syringe cylinder 2 into two cylinder chambers 11 and 13.
  • an injection device 1 according to the invention, which comprises a syringe cylinder 2 and a piston 8, which divides the syringe cylinder 2 into two cylinder chambers 11 and 13.
  • the latching arms are arranged and is designed as a cone.
  • the latching arms run in the one adjoining the projection 241 part extending in the direction of the piston rod 6 over a length which corresponds at least to the distance 251, parallel to the longitudinal axis 202 of the syringe barrel 2.
  • An incline of the conical end of the expanding core 252 is selected such that there is a relative adjustment between the locking arms 242 and the expansion core 252 by a distance 253 which is at least slightly smaller than the distance 251, the latching arms 242 are pivoted apart in the radial direction by an expansion path 254 which has at least one overlap width 255 between the locking lugs 243 and the projection 241 corresponds.
  • a locking lug 256 protruding in the direction of the cone is arranged.
  • the piston can be withdrawn via the locking lugs 243 of the latching arms 242 against an extrusion direction shown by an arrow 248. If, now, the solution to be pressed 221 out of the cylinder chamber 11 through the outlet 5, so the piston rod 6 in the direction "of the outlet 5, ie in the direction of the arrow 248 is moved.
  • the feed force caused by the expanding core 252 in the direction of the longitudinal axis 202 is not sufficient, so that the locking arms 242 are pushed ever closer to the rear 231 of the piston 8 until the expanding core 252 engages in the latching lugs 256 and thus the latching arms 242 arrive in the position shown in broken lines.
  • the locking lugs 243 are no longer in engagement with the projection 241, and from this moment the piston 8 can only be supported by the locking lugs 243 of the locking arms 242 being supported directly on the rear side 231 of the piston 8 in the direction of the Outlet 5 are moved.
  • the coupling arrangement 3 is arranged on a tubular outlet 5 of the syringe barrel 2.
  • a piston rod 6 is arranged so as to be displaceable in the longitudinal direction thereof and is connected in motion to a piston 8 via a coupling device 7.
  • An unlocking or triggering device 9 is assigned to the clutch device 7.
  • the piston 8 can consist of a rubber or plastic part or a corresponding plastic insert, on the circumference of which sealing elements, such as O-rings or rubber sleeves or the like, are arranged.
  • the plunger 8 lies against an inner wall 10 of the syringe barrel 2 and divides it into a cylinder chamber 11 connected to the outlet 5 and an opening 12 of the syringe barrel 2 associated cylinder chamber 13.
  • the piston 8 is essentially a tubular component, which forms a piston surface 314 at its end facing the outlet 5.
  • An approximately bead-shaped guide extension 315 is arranged on its end opposite the piston surface 314.
  • the coupling device 7 of a tamper-evident device 317 is arranged in the recess 316 formed by the tubular component.
  • a range of motion 325 in which the piston rod 6 can move relative to the piston 8 is through an end wall 326 of the piston 8 in one direction and in the opposite direction, that is to say toward the opening 12 of the syringe barrel 2, through which the support surfaces 322 the coupling elements 321 limited.
  • the piston rod 6 can thus move a distance 327 from the position shown in full lines to the position shown in broken lines.
  • An actuating element 328 counteracts the common forward movement of the coupling elements with the actuator 324 arranged between their contact surfaces 323.
  • This actuating member 328 forms the unlocking or triggering device 9 and is arranged in the recess 316 and connected in one piece to the piston 8.
  • the actuator 328 is approximately frustoconical and aligned concentrically to the longitudinal axis 318 and extends from the end wall 326 of the piston 8 in the direction of the actuator 324.
  • the actuator 324 ensures that the coupling elements 319 overlap with the coupling element 321 in a use position in which the lugs 320 engage the coupling element 321, the support surface 322 of the piston 8. This will prevent that with a zie Zugur ⁇ h s of the piston 8 from the solid lines to the position indicated in broken lines position, the piston 8 with the piston rod 6 is taken. As a result, when the injection device 1 is pulled open, medicament can be drawn in from a container via the injection needle 4.
  • the recess 316 of the piston 8 has a depth 332 which is equal to or greater than that Sum of a length 333 of the contact surface 323 of the coupling elements 319 and a height 334 of the actuating element 328. Furthermore, a width 335 of the actuating element 328 is smaller than a distance 336 between the lugs 320 in their rest position and a distance 337 of the clearance space 331 larger than a diameter 338 of the actuator 324.
  • the radially adjustable coupling elements 319 can thereby reach a rest position, in which they are located within a conical envelope surface that tapers in the direction of the end wall 326 of the piston B.
  • the fact that an outer width 339 between the lugs 320 of the coupling elements 319 which are in the rest position is smaller than a width 340 of an opening 341 of the piston 8 means ⁇ ip lugs 320 and the support surface 322 in this position.
  • FIG 17 is to the actuator 324 in position between the de-- Kuoplungsele ducks 319 dargest- Mt.
  • the actuator 324 is ': where au- integrally a substantially cylindrical body having • teretzlichen diameters formed, wherein a the' 328 Wennungsglied opposite diameter 342 is larger and a transition 343 to a smaller diameter range is formed by a truncated cone.
  • the surface area with the diameter 342 forms an expansion surface 344 for the contact surface 323 of the coupling elements 319.
  • the contact surface 323 has extensions 345 associated with the transition 343, which protrude beyond the contact surface 323 in the direction of the longitudinal axis 318.
  • This design of the actuator 324 and the increased resistance which has to be overcome in order to release the movement of the coupling elements or to decouple or push out the actuator 324 prevent the piston rod 6 from getting in Rich in the event of an inadvertent incorrect movement ⁇ device of the injection needle 4 before the medication is pulled out the decoupling process takes place and thus the injection device 1 is unusable.
  • FIG. 18 shows an actuator 324 with a locking pin 347, which acts in the direction of the longitudinal axis 318 and which acts as a spacer element 348, which is arranged on the end of the actuator 324 opposite the actuator 328.
  • This locking pin 347 supports the actuator 324 against a force, corresponding to the arrow 346 in the direction of the piston rod 6.
  • the locking pin 347 is kinked, as a result of which the actuator 324 can be pressed into the position shown in dashed lines and thus, as already shown that of Figure 2, the coupling device 7 solved.
  • a desired resistance value against the triggering of the clutch device 7 can also be selected in this embodiment.
  • the locking pin 347 can be integrally connected to the actuator 324, for example molded, as is also possible to glue, weld or inject it on the end face. To achieve a suitable kink resistance, it is of course also possible to manufacture the locking pin 347 from a wide variety of materials.
  • FIG. 19 shows a further embodiment variant of the actuator 324, in which the spacer element 348 is shown by a spring arrangement 349, which is arranged in the free space 331 between the coupling elements 319.
  • the spring arrangement 349 is formed from at least two spring elements 350 which are connected to the piston rod 6 in terms of movement.
  • the spring elements 350 extend approximately at an angle between 30 degrees and 50 degrees, preferably 45 degrees, from the longitudinal axis 318 in the direction of the piston 8 and are arranged within a slot 351 of the coupling elements 319.
  • the protruding end of the spring element 350 has a joint arrangement 352 in which a push rod 353 is mounted.
  • This arrangement forms a so-called over-center lock which, due to the action of the spring elements 350, causes the actuator 324 to move Direction of arrow 356 provides resistance.
  • Form expansion element 35B Furthermore, it is possible to provide these spacing elements 34 ⁇ with weakening cross sections 359 in order to influence the buckling behavior and thus to determine the desired resistance to a deformation force in the direction of arrow 356.
  • FIGS. 22 and 23 Another embodiment variant for the coupling device 7 is shown in FIGS. 22 and 23.
  • the piston B has an approximately cylindrical recess 316 with a diameter 360 that is larger than a diameter 361 of one
  • the region of the recess 316 which is arranged opposite the opening 362 is provided with a truncated cone-shaped constriction. Due to the different diameters 360, 361, the annular support surface 322, which is arranged approximately perpendicular to the longitudinal axis 318, is formed for the projections 320 of the coupling elements 319 connected to the piston rod 6 and projecting in the direction of the piston 8.
  • the end region of the coupling elements 319 has a bevel, which, in cooperation with the frustoconically narrowing recess 316 of the piston 8, causes a movement of the end regions of the coupling elements 319 and thus of the lugs 320 with a relative movement between the piston and the piston rod 6 .
  • On the opposite inner surfaces 363, the coupling tion elements 319 a locking device 364, which is formed by oppositely arranged hook-shaped extensions 365.
  • the latching device 364 is brought into engagement after a stroke 366 has been covered and the coupling elements 319 are positioned in a position in which a width 367 of the lugs 320 is smaller than the diameter 361 of the opening 362 of the piston 8.
  • the clutch device 7 f disengaged and moving the piston 8 by means of the piston rod 6 in the direction of P eiles 356 no longer possible.
  • the injection device 1 can no longer be refilled with a medicament and thus effective protection against reuse of such an injection device 1 is provided.
  • FIG. 24 shows that, according to the invention, the clutch device 7 can also be formed by the clutch elements 319 being arranged on the piston 8.
  • the piston rod 6 has the support surface 322 forming the coupling element 321 for the lugs 320 of the coupling elements 319.
  • the active position of the coupling elements is achieved by the actuator 324 arranged between the coupling elements 319.
  • the actuating element 328 protruding in the direction of the actuator 324 is arranged on an end face 369 of a recess 370 of the piston rod 6 facing the piston B.
  • the actuator 324 is moved be ⁇ from the actuator 328 in a space 371 between the coupling elements 319, whereby they by their radial adjustability in i rs in dashed lines shown rest position, b ei the clutch device 7 is released and the width 367 between the lugs 320 of the coupling elements 319 is smaller than an opening width 372 of the piston rod 6.
  • the parts fastened to the piston rod can optionally be exchanged for the parts fastened to the piston.
  • the coupling elements usually overlap one another in regions in order to enable locking or entrainment of the individual parts
  • An advantage of the previously described embodiments of the injection device designed according to the invention is that the material fatigue does not adversely affect the safe function for uncoupling the piston, even when the injection devices 1 are stored for a longer period of time. bens 8 can affect the piston rod 6. It is particularly advantageous here if the pretensioning of the coupling elements, which enables the coupling elements 319, 321 to be decoupled by changing their distance from one another or the envelope circle diameter enclosing them, are made of plastic, so that after removing the actuator ⁇ member 324 these return to their smaller dimensions and thus can emerge from the coupling element 321 enclosing them.
  • FIG 25 is with the cylinder 401 of a disposable syringe be ⁇ lines, in which a piston 402 is found * mult, wherein the end face 403 sealingly engages the inner surface of the cylinder four hundred and first Guide ribs 404 are also indicated for guiding the piston.
  • the cylinder 401 has a syringe cone 405, on which a cannula can be attached before the syringe is used.
  • the piston "402 has on its end face 403 a projecting to the syringe cone 405 latch part 406 on whose greatest external diameter a larger than the smallest inner diameter b in the interior of the syringe cone 405.
  • latch part 406 For locking the locking member in the syringe cone 405 on En d e d it Spritzenhubes is the locking part 406 remote, as indicated by 407.
  • the shoulder 407 interacts with a stop 40B which is arranged on the inner surface of the syringe cone 405 and defines the smallest inside diameter of the same, so that after a movement of the piston 402 into the end position of the syringe stroke Locking of the locking part 406 by the interaction of the shoulders or stops 407 and 408 takes place as shown in FIG.
  • the syringe cone has a predetermined breaking point in the area facing the cylinder 401, which is formed by a circumferential groove 409. Above this predetermined breaking point, the spike cone 405 carries drivers 410, which can be formed in a particularly simple manner by an external toothing.
  • the locking part 406 is designed as a pin which can be inserted into the piston end face, so that after the locking part 406 has been locked in the syringe cone 405, thereby preventing further use of the syringe by preventing it from being opened again, the piston 402 is released from the locking member can and is used for disposal of the cannula 411 used.
  • an internal toothing 413 provided in the grip area 412 of the piston 402 interacts with the toothing or the drivers 410 on the syringe cone, so that after the catches 410 or inner toothing 413 are snapped in, the syringe cone is rotated when the piston 402 is turned In the area of its predetermined breaking point, for example a circumferential groove 409 breaks, and the remnants of the syringe cone 405, together with the cannula 411, are safely held inside the piston 402.
  • the two separate components of the disposable syringe, namely the cylinder 401 and the piston 402 with the cannula 411 accommodated in its interior are therefore unsuitable for further use, as is clearly shown in FIGS. 4 and 5.
  • the piston 402 in turn has a locking part 406 in the region of its end face 403, which is locked by stops 408 at the end of the syringe stroke with stops 408 on the syringe cone.
  • the locking member has axially extending slots 414.
  • the locking member 406 is in turn designed to be detachable from the piston 402, with carriers formed by a toothing 415 being provided for securing the bearing.
  • elastically deformable and axially projecting stops 416 are provided on the end face 403, which stop before the further pulling up of the Oppose piston 402 in the setting for slight resistance.
  • this resistance can easily be overcome in order to discharge the entire and desired amount of the pharmaceutical agent, whereupon when the end face 403 is in contact with the end face of the cylinder, a locking mechanism via the interacting stops or Paragraphs 407 and 408 take place.
  • the opening in the plunger intended for receiving the locking part 406 and the one for securing the position of the locking part 406 can now be provided.
  • ⁇ ese h enes driver 410 for disposal of the cannula 411 be pulled up.
  • the end face 403 is guided over the cannula 411 until the drivers 410 on the syringe cone 405 engage with the drivers 410 in the region of the end face 403 and the syringe cone 405 after twisting the piston together with the cannula 411 after tearing the syringe cone 405 is received in the area of its predetermined breaking point inside the piston 402.
  • 31 to 33 show an embodiment variant of the injection device 1 according to the invention, which in turn has a syringe cylinder 2, an injection needle 3 and a coupling arrangement 3 for connecting the injection needle 3 to the syringe cylinder 2.
  • a piston 8 is arranged in the interior of the syringe cylinder 2 and is coupled to the piston rod 6 via a coupling device 7.
  • the piston rod 6 comprises a central part 420 which has, for example, a circular cross section and from which guide flanges 421 project in the radial direction at 90 degrees.
  • Coupling elements 319 designed as latching arms 423 protrude from an end face 422 of the piston rod 6 facing the piston.
  • the coupling elements 319 are provided with a shoulder 320, which is provided with locking lugs 424 projecting outwards in the circumferential direction and on the opposite inside with an internal thread 425.
  • the locking lugs 424 have support surfaces 322 which are supported on projections 426, which form coupling elements 321 and are fixedly connected to the piston 8.
  • the projections 426 protrude over the surface of a recess 427 in the direction of the latching arms 423.
  • Ijie approaches 320 are biased towards the surface of the recess 427 by a tension member 428, so that the detents 424 and the projections 426 overlap.
  • the tensioning member 428 protrudes in the direction of an end face 429 of the piston 8 and is supported on an actuating member 328 extending from the end face 429 in the direction of the piston rod 6.
  • the actuating member 328 and the tensioning member 428 form the triggering device 9.
  • the tensioning member 428 is provided on its surface with an external thread 430. This external thread is designed as a steep thread.
  • the internal thread 425 and the external thread 430 belong to the same thread type, so that the tensioning member 428 is adjustably mounted in the internal thread 425.
  • the piston rod 6 must be moved in the direction of an arrow 431.
  • the feed force in the direction of arrow 431 is transmitted from the piston rod 6 to the piston 8 by the tensioning member 428 to the actuating member 328 of the piston 8.
  • the compressive force exerted on the piston via the piston rod 6 now causes the tensioning member 428 to move about a central longitudinal axis 432 owing to the steep thread which is used for the external thread 430 starts to turn. This leads to the fact that the tensioning member 428 moves back from the position shown in FIG. 31 to the position shown in FIG. 33, a perfect drive connection both in the direction of arrow 431 and over this entire path covered during this exertion of the pressure force given in an opposite direction.
  • the piston 433 shown in FIG. 33 also allows the piston to be withdrawn at any time counter to the direction of advance of the arrow 431.
  • This lifting height 433 can thus be used for aspiration.
  • This process of aspiration is important after the injection needle has been inserted into a body for the administration of a medicament in order to determine whether or not the person administering the liquid medication has hit a blood vessel. This is determined by applying a small amount of the liquid medication, whereupon the plunger is pulled back against the direction of arrow 431. If the person administering the medication has now hit a vein, for example, he pulls blood into the syringe barrel 2 when the plunger 8 is withdrawn. Because of the transparent design of the syringe barrel 2, the person administering the medication can therefore recognize this immediately.
  • This construction of the injection device 1 thus ensures that after the application of a quantity of medication which is greater than that quantity of medication required for aspiration, the action of the triggering device 9 means that the injection device 1 is released by the uncoupling of the piston 8 and the piston rod 6 is destroyed and the injection device can therefore no longer be used for a further injection process.
  • the design of the latching arms 423 in particular their shape in order to achieve a pretension directed in the direction of the actuating member 328, can also be freely selected. It is thus possible to manufacture the piston, which in particular consists of a molded plastic part, with the directly integrally formed latching arms 423 in such a way that the latching arms assume the shape shown in FIG. 32, and in the position according to FIG .31 are held only by the expansion effect with the tendon 428. On the other hand, it is also possible to design the support surfaces 322 as a conical surface 8 widening in the direction of the piston 8, so that after the tension member 428 has been removed and the piston rod 6 has been withdrawn from the piston 8.
  • the locking arms 423 are pressed together, and thus also a decoupling of the elements 319 and 321 forming the coupling device 7 takes place.
  • any other embodiment known in the art that is suitable for this purpose is applicable. It is only essential that the drive connection between the piston rod 6 and the piston 8 is maintained over the desired lifting height 433 and then automatically released, so that a single use of the injection device 1 is ensured with a high degree of certainty.
  • 34 to 37 show a further embodiment of an injection device 1, in which only a part of the syringe cylinder 2 is shown, the connection between the syringe cylinder 2 and the injection needle 3 corresponding to the exemplary embodiments described in the preceding figures or according to FIGS Designs from the prior art can be formed.
  • FIGS. 15 to 17 This embodiment is in principle similar to the embodiment shown in FIGS. 15 to 17, which is why the same reference numerals are used for the same parts.
  • a piston guided in the syringe cylinder 2 is again arranged! which is connected to the piston 8 by means of a coupling device 7, in the embodiment described in detail in FIGS. 15 to 17.
  • the coupling elements 319 and 321, which are designed as projections 426 or locking lugs 424, serve this purpose.
  • the actuator 324 is provided, which is actuated by the actuator.
  • tion member 328 forms a trigger device 9.
  • the support arms 437 are deformed in the direction of the longitudinal axis 318 after the projections 440 have entered the syringe cylinder 2, so that the support arms 437 are no longer on the Support the end face 441 of the piston 8 facing the piston rod 6, but instead enter the recess 434 within the coupling elements 321. However, this also moves the coupling elements 319 in the direction of the piston surface 314.
  • the actuator 328 pushes the actuator 324 into the free space 331 between the coupling elements 319, so that there is no longer any overlap between the lugs 320 and the support surfaces 322. This is an unlock tion between the piston rod 6 and the piston 8 reached. If the user now tries to pull the piston 8 out of the syringe cylinder 2 again with the piston rod 6 in order to draw up further medication, the coupling elements 319 emerge unhindered from the recess 434 and the piston rod releases from it without it to take the piston 8.
  • the piston rod 6 comprises four support arms 437, each offset by 90 degrees to one another in the circumferential direction, and the coupling elements 319 are also designed in the form of a segment of a circle and separated from one another by slots 442.
  • the arrangement of the support arms 437 or coupling elements 319 distributed over the circumference prevents the various individual parts from being forced into the syringe barrel even when handled carelessly, thereby ensuring rapid and safe actuation of the injection device.
  • a feed size 436 for the aspiration can now be adapted in a simple manner by the arrangement of the projections 440 to different applications of the injection devices 1.
  • this injection device has only one single part, namely the actuator 324.
  • the manufacturing costs are thus very low and the mass use of such an injection device, especially in the developing countries, is possible with a high level of security against repeated use.
  • With the injection devices according to the invention described above in the various exemplary embodiments it is advantageously possible to produce all individual parts from plastic. Only in the case of very small injection devices, for better sealing of the plunger 8 from the syringe barrel 2, is it advisable to arrange an O-ring made of rubber or the like for sealing purposes in the region of the plunger 8.
  • Parts, such as the actuator 324 or the piston 8 can be made of a silicone rubber or optionally a stainless steel or the like.
  • the syringe barrel 2 it is also possible for the syringe barrel 2 to consist of both plastic and glass.
  • FIG. 38 A further injection device 1 is shown in FIG. 38, which is essentially designed in accordance with the embodiment shown in FIGS. 34 to 37.
  • the same reference numerals are therefore used for the same parts.
  • the embodiment shown in FIG. 38 now differs from that shown in FIGS. 34 to 37 in that the actuation of the support arms 437 instead of the interaction of the projections 440 with the inside of the syringe barrel 2 is due to the interaction of the support arms 437 with one between the same and the inside of the syringe barrel arranged retaining ring 442.
  • the support arms 437 are provided with links 443, which are assigned to the locking ring 442 arranged between the support arms 437 and the syringe cylinder 2.
  • This, for example, C-shaped locking ring 442 has an inner diameter 444 which is smaller than a diameter 445 of an enveloping circle surrounding the support arms 445.
  • the ins special C-shaped locking ring is also preloaded in the radial direction or has a larger outside diameter than the inside diameter of the syringe barrel 2. As a result, it can only be displaced in the longitudinal direction of the syringe barrel 2 when considerable force is exerted. For this purpose, it can also be provided with corresponding roughening on the outside facing the syringe barrel 2.
  • a length 447 of the stop 320 is shorter than a length 448 of a guide surface 449 of the locking arms 437.
  • a height of the projections 440 is dimensioned such that it deforms the locking arms 437 by a pivoting angle 450, which leads to an inward adjustment of the locking arms 437 by an amount greater than an overlap width 451. Furthermore, for a reliable release of the coupling connection, it is advantageous if a distance 452 is greater than the length 448.

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  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

Un dispositif d'injection (1) à usage unique comprend un cylindre d'injection (2) qui contient un piston (8) et une tige de piston (6) reliée au piston, notamment par un dispositif de couplage (7). La tige de piston est de préférence plus longue que le cylindre d'injection (2). Un agencement de couplage (3) agencé du côté de l'ampoule opposé à la tige de piston (6) permet de coupler une aiguille d'injection (4) avec le cylindre d'injection (2). Un dispositif de déclenchement (9) et/ou un sceau de garantie (27) sont associés au piston (8) et/ou à la tige de piston (6).
PCT/AT1989/000088 1988-10-03 1989-10-03 Dispositif d'injection a usage unique WO1990003816A1 (fr)

Priority Applications (3)

Application Number Priority Date Filing Date Title
BR898907685A BR8907685A (pt) 1988-10-03 1989-10-03 Dispositivo de injecao para uso uma so vez
KR1019900701176A KR900701341A (ko) 1988-10-03 1990-06-04 일회용 주사기
DK58191A DK58191D0 (da) 1988-10-03 1991-04-02 Engangssproejte

Applications Claiming Priority (10)

Application Number Priority Date Filing Date Title
ATA2440/88 1988-10-03
AT244088A AT395535B (de) 1988-10-03 1988-10-03 Einwegspritze
ATA387/89 1989-02-21
AT38789A ATA38789A (de) 1989-02-21 1989-02-21 Injektionsvorrichtung mit einer originalitätssicherungsvorrichtung
ATA493/89 1989-03-06
AT49389 1989-03-06
ATA1131/89 1989-05-11
AT113189A ATA113189A (de) 1989-05-11 1989-05-11 Injektionsvorrichtung mit einer ein öffnungsorgan aufweisenden originalitätssicherungsvorrichtung
AT167189 1989-07-10
ATA1671/89 1989-07-10

Publications (1)

Publication Number Publication Date
WO1990003816A1 true WO1990003816A1 (fr) 1990-04-19

Family

ID=27506167

Family Applications (1)

Application Number Title Priority Date Filing Date
PCT/AT1989/000088 WO1990003816A1 (fr) 1988-10-03 1989-10-03 Dispositif d'injection a usage unique

Country Status (5)

Country Link
KR (1) KR900701341A (fr)
AU (1) AU4337989A (fr)
BR (1) BR8907685A (fr)
HU (1) HU895714D0 (fr)
WO (1) WO1990003816A1 (fr)

Cited By (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5242400A (en) * 1991-12-06 1993-09-07 The Medtech Group, Inc. Disposable pre-filled syringe with retractable needle
FR2707173A1 (fr) * 1993-05-05 1995-01-13 Alloiteau Jean Pierre Seringue hypodermique à usage unique comportant un pion à évidement de communication provisoire entre les deux chambres de la seringue.
WO2000006234A1 (fr) * 1998-07-29 2000-02-10 Becton, Dickinson And Company Seringue a usage unique
DE102004001811A1 (de) * 2004-01-13 2005-08-18 Tecpharma Licensing Ag Kanüleneinheit mit Verpackungshülse
US6986756B2 (en) 2001-09-24 2006-01-17 Becton, Dickinson And Company Single use syringe and plunger rod locking device therefor
US7798993B2 (en) 1998-07-29 2010-09-21 Becton, Dickinson And Company Single use syringe
US8202257B2 (en) 1998-07-29 2012-06-19 Becton, Dickinson And Company Splatter prevention mechanism for a syringe
CN113272002A (zh) * 2018-11-23 2021-08-17 Sfm医疗设备有限责任公司 用于利用套管放置元件的设备

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0229017A2 (fr) * 1986-01-07 1987-07-15 Christian Sandsdalen Seringue d'injection à usage unique
EP0336855A1 (fr) * 1988-03-21 1989-10-11 Microtechnic S.A. Seringue à usage unique

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0229017A2 (fr) * 1986-01-07 1987-07-15 Christian Sandsdalen Seringue d'injection à usage unique
EP0336855A1 (fr) * 1988-03-21 1989-10-11 Microtechnic S.A. Seringue à usage unique

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5242400A (en) * 1991-12-06 1993-09-07 The Medtech Group, Inc. Disposable pre-filled syringe with retractable needle
FR2707173A1 (fr) * 1993-05-05 1995-01-13 Alloiteau Jean Pierre Seringue hypodermique à usage unique comportant un pion à évidement de communication provisoire entre les deux chambres de la seringue.
WO2000006234A1 (fr) * 1998-07-29 2000-02-10 Becton, Dickinson And Company Seringue a usage unique
US7798993B2 (en) 1998-07-29 2010-09-21 Becton, Dickinson And Company Single use syringe
US8202257B2 (en) 1998-07-29 2012-06-19 Becton, Dickinson And Company Splatter prevention mechanism for a syringe
US9308331B2 (en) 1998-07-29 2016-04-12 Becton, Dickinson And Company Splatter prevention mechanism for a syringe
US6986756B2 (en) 2001-09-24 2006-01-17 Becton, Dickinson And Company Single use syringe and plunger rod locking device therefor
DE102004001811A1 (de) * 2004-01-13 2005-08-18 Tecpharma Licensing Ag Kanüleneinheit mit Verpackungshülse
CN113272002A (zh) * 2018-11-23 2021-08-17 Sfm医疗设备有限责任公司 用于利用套管放置元件的设备
CN113272002B (zh) * 2018-11-23 2023-09-12 Sfm医疗设备有限责任公司 用于利用套管放置元件的设备

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BR8907685A (pt) 1991-07-30
AU4337989A (en) 1990-05-01
HU895714D0 (en) 1992-01-28
KR900701341A (ko) 1990-12-01

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