UY36074A - ?derivados de dihidropirrolopirimidina? . - Google Patents

?derivados de dihidropirrolopirimidina? .

Info

Publication number
UY36074A
UY36074A UY0001036074A UY36074A UY36074A UY 36074 A UY36074 A UY 36074A UY 0001036074 A UY0001036074 A UY 0001036074A UY 36074 A UY36074 A UY 36074A UY 36074 A UY36074 A UY 36074A
Authority
UY
Uruguay
Prior art keywords
compounds
derivatives
treatment
cellular
dihydropirrolopirimidina
Prior art date
Application number
UY0001036074A
Other languages
English (en)
Inventor
Orr Suvi Tuula Marjukka
Chen Ping
Gallego Gary Michael
Jalaie Mehran
Shen Hong
Cheng Hengmiao
Kath John Charles
Deal Judith Gail
Zehnder Luke Raymond
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of UY36074A publication Critical patent/UY36074A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/5375—1,4-Oxazines, e.g. morpholine
    • A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00—Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06—Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
    • A61N5/00—Radiation therapy
    • A61N5/10—X-ray therapy; Gamma-ray therapy; Particle-irradiation therapy
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • C07F9/65616—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system having three or more than three double bonds between ring members or between ring members and non-ring members, e.g. purine or analogs

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • Radiology & Medical Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L A Presente Invención S E Refiere A Compuestos De La Fórmula (X) O S A Le S Farmacéuticamente Aceptables De Los Mismos , En Donde R1 -R5 0 , A, B, D, E, F , G , H, I , J , K , L , O, P, Q , R , S , T , U, Y Y Z Son Definidos En La Presente. Los Derivado S De Dihidropirrolop Irimidina No Vedosos Son Út Iles En El Tratamiento De Crecimiento Celular A Normal , Tal Como Cáncer , En Mamífero S . L As Modalidades A D I C Ion Ales Se Refieren A Composición Es Farmacéuticas Que Contienen Los Compuest Os Y A Métodos De Usar Los Compues T Os Y Composiciones E N E L Tratamiento Decrec Imient O Celular Anorma L En Mamíferos .
UY0001036074A 2014-04-10 2015-04-10 ?derivados de dihidropirrolopirimidina? . UY36074A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201461978168P 2014-04-10 2014-04-10

Publications (1)

Publication Number Publication Date
UY36074A true UY36074A (es) 2015-11-30

Family

ID=52988359

Family Applications (1)

Application Number Title Priority Date Filing Date
UY0001036074A UY36074A (es) 2014-04-10 2015-04-10 ?derivados de dihidropirrolopirimidina? .

Country Status (5)

Country Link
US (1) US9260439B2 (es)
AR (1) AR099988A1 (es)
TW (1) TW201542557A (es)
UY (1) UY36074A (es)
WO (1) WO2015155624A1 (es)

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WO2021247862A1 (en) * 2020-06-03 2021-12-09 Yumanity Therapeutics, Inc. Bicyclic heteroarenes and methods of their use
JP2023535279A (ja) 2020-06-22 2023-08-17 コーセプト セラピューティクス， インコーポレイテッド ４級インダゾールグルココルチコイド受容体アンタゴニスト
AU2022421212A1 (en) 2021-12-21 2024-07-04 Corcept Therapeutics Incorporated Bicyclic indazole glucocorticoid receptor antagonists
IL313663A (en) 2021-12-21 2024-08-01 Corcept Therapeutics Inc Piperazine indazole glucocorticoid receptor antagonists

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Also Published As

Publication number Publication date
US20150291604A1 (en) 2015-10-15
WO2015155624A1 (en) 2015-10-15
TW201542557A (zh) 2015-11-16
AR099988A1 (es) 2016-08-31
US9260439B2 (en) 2016-02-16

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Legal Events

Date Code Title Description
109 Application deemed to be withdrawn

Effective date: 20220617