UY34525A - Un medicamento inhalable - Google Patents
Un medicamento inhalableInfo
- Publication number
- UY34525A UY34525A UY0001034525A UY34525A UY34525A UY 34525 A UY34525 A UY 34525A UY 0001034525 A UY0001034525 A UY 0001034525A UY 34525 A UY34525 A UY 34525A UY 34525 A UY34525 A UY 34525A
- Authority
- UY
- Uruguay
- Prior art keywords
- medicinal product
- formulation
- inhalable medicinal
- inhalable
- percentages
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/12—Carboxylic acids; Salts or anhydrides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/009—Inhalators using medicine packages with incorporated spraying means, e.g. aerosol cans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Otolaryngology (AREA)
- Emergency Medicine (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Anesthesiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
UN MEDICAMENTO INHALABLE Esta invención se refier e a una formulación en solución que comprende una sal de tiotropio, 12-20% de etanol, 0,1-1,5% de agua, 0,05-0,10% de ácido cítrico (u otro ácido orgánico) y un propelente de HFA, en donde los porcentajes son porcentajes en peso en base al peso total de la formulación. La invención también proporciona un pMDI que comprende una lata que contiene la formulación.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US201161577315P | 2011-12-19 | 2011-12-19 | |
GBGB1200525.2A GB201200525D0 (en) | 2011-12-19 | 2012-01-13 | An inhalable medicament |
Publications (1)
Publication Number | Publication Date |
---|---|
UY34525A true UY34525A (es) | 2014-07-31 |
Family
ID=45813952
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UY0001034525A UY34525A (es) | 2011-12-19 | 2012-12-18 | Un medicamento inhalable |
Country Status (29)
Country | Link |
---|---|
US (1) | US9655969B2 (es) |
EP (3) | EP3143998B1 (es) |
JP (1) | JP5791166B2 (es) |
KR (2) | KR101670564B1 (es) |
CN (1) | CN103998039A (es) |
AR (1) | AR089302A1 (es) |
AU (1) | AU2012358475B2 (es) |
BR (1) | BR112014014535A2 (es) |
CA (1) | CA2856047C (es) |
CY (1) | CY1116142T1 (es) |
DK (3) | DK3143998T3 (es) |
EA (1) | EA028461B1 (es) |
ES (3) | ES2728940T3 (es) |
GB (1) | GB201200525D0 (es) |
HK (2) | HK1198512A1 (es) |
HR (1) | HRP20141176T1 (es) |
HU (2) | HUE044647T2 (es) |
IL (1) | IL232946A0 (es) |
MX (1) | MX361925B (es) |
PL (3) | PL2793886T3 (es) |
PT (1) | PT2606891E (es) |
RS (1) | RS53783B1 (es) |
SI (1) | SI2606891T1 (es) |
SM (1) | SMT201400192B (es) |
TR (1) | TR201908429T4 (es) |
TW (1) | TWI468187B (es) |
UY (1) | UY34525A (es) |
WO (1) | WO2013092237A1 (es) |
ZA (2) | ZA201403041B (es) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
MY156950A (en) | 2009-12-23 | 2016-04-15 | Chiesi Farma Spa | Aerosol formulation for copd |
GB201200525D0 (en) | 2011-12-19 | 2012-02-29 | Teva Branded Pharmaceutical Prod R & D Inc | An inhalable medicament |
EP2819669B1 (de) | 2012-02-28 | 2021-04-21 | Boehringer Ingelheim International GmbH | Neue treibgashaltige tiotropium-formulierung |
EP2897589B1 (en) * | 2013-11-22 | 2018-01-03 | Teva Branded Pharmaceutical Products R & D, Inc. | An inhalable medicament |
MX2016006377A (es) * | 2013-11-22 | 2016-10-28 | Teva Branded Pharmaceutical Products R&D Inc | Un medicamento inhalable. |
US10034866B2 (en) | 2014-06-19 | 2018-07-31 | Teva Branded Pharmaceutical Products R&D, Inc. | Inhalable medicament comprising tiotropium |
US20190054010A1 (en) * | 2015-10-29 | 2019-02-21 | 3M Innovative Properties Company | Formulation and aerosol canisters, inhalers, and the like containing the formulation |
EP3922240B1 (en) * | 2016-09-19 | 2023-06-21 | Mexichem Fluor S.A. de C.V. | Pharmaceutical composition comprising tiotropium bromide |
WO2020006017A1 (en) * | 2018-06-27 | 2020-01-02 | 3M Innovative Properties Company | Tiotropium formulation and inhaler |
Family Cites Families (57)
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GB8828477D0 (en) | 1988-12-06 | 1989-01-05 | Riker Laboratories Inc | Medical aerosol formulations |
US5610163A (en) | 1989-09-16 | 1997-03-11 | Boehringer Ingelheim Gmbh | Esters of thienyl carboxylic acids and amino alcohols and their quaternization products |
DE3931041C2 (de) | 1989-09-16 | 2000-04-06 | Boehringer Ingelheim Kg | Ester von Thienylcarbonsäuren mit Aminoalkoholen, ihre Quaternierungsprodukte, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel |
GB9026191D0 (en) * | 1990-12-01 | 1991-01-16 | Harris Pharma Ltd | Breath actuated dispensing device |
EP0616525B1 (en) | 1991-12-12 | 1995-09-27 | Glaxo Group Limited | Pharmaceutical aerosol formulation |
IL104068A (en) | 1991-12-12 | 1998-10-30 | Glaxo Group Ltd | Pharmaceutical preparations in a spray without surfactant containing 1, 1, 1, 2 tetrafluoroethane or 1,1,2,3,3 petafluor N propane as propellant |
GB2264238A (en) | 1992-05-29 | 1993-08-25 | Norton Healthcare Ltd | Medicament inhalor device |
AU680227B2 (en) * | 1992-12-09 | 1997-07-24 | Boehringer Ingelheim Pharmaceuticals, Inc. | Stabilized medicinal aerosol solution formulations |
US6258341B1 (en) | 1995-04-14 | 2001-07-10 | Inhale Therapeutic Systems, Inc. | Stable glassy state powder formulations |
US6309671B1 (en) | 1995-04-14 | 2001-10-30 | Inhale Therapeutic Systems | Stable glassy state powder formulations |
GB9616237D0 (en) | 1996-08-01 | 1996-09-11 | Norton Healthcare Ltd | Aerosol formulations |
EP1131059B1 (de) | 1998-11-13 | 2003-03-05 | Jago Research Ag | Trockenpulver zur inhalation |
DZ2947A1 (fr) | 1998-11-25 | 2004-03-15 | Chiesi Farma Spa | Inhalateur à compteur de dose sous pression. |
EP1238661A1 (en) | 1999-10-12 | 2002-09-11 | Kaken Pharmaceutical Co., Ltd. | Powdery inhalational preparations and process for producing the same |
US20060257324A1 (en) | 2000-05-22 | 2006-11-16 | Chiesi Farmaceutici S.P.A. | Pharmaceutical solution formulations for pressurised metered dose inhalers |
ME00220B (me) | 2000-05-22 | 2010-10-10 | Chiesi Farm Spa | Stabilne farmaceutske formulacije rastvora za inhalatore odmjerene doze pod pritiskom |
US6553988B1 (en) | 2000-06-09 | 2003-04-29 | Norton Healthcare, Inc. | Medicament dispensing device with a multimaterial diaphragm bounding a pneumatic force chamber |
US6908928B2 (en) | 2000-10-12 | 2005-06-21 | Bi Pharma Kg. | Crystalline tiotropium bromide monohydrate, processes for the preparation thereof, and pharmaceutical compositions |
ATE275391T1 (de) | 2000-10-12 | 2004-09-15 | Boehringer Ingelheim Pharma | Neue tiotropium-haltige inhalationspulver |
WO2002030928A1 (de) | 2000-10-12 | 2002-04-18 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Kristallines monohydrat, verfahren zu dessen herstellung und dessen verwendung zur herstellung eines arzneimittels |
ES2185606T3 (es) * | 2001-03-21 | 2003-05-01 | Sanol Arznei Schwarz Gmbh | Nuevo uso de una clase de compuestos peptidicos para tratamiento de la alodinia u otros tipos diferentes de dolor cronico o fantasma. |
US20030070679A1 (en) | 2001-06-01 | 2003-04-17 | Boehringer Ingelheim Pharma Kg | Capsules containing inhalable tiotropium |
DE10126924A1 (de) | 2001-06-01 | 2002-12-05 | Boehringer Ingelheim Pharma | Inhalationskapseln |
US6608055B2 (en) | 2001-06-22 | 2003-08-19 | Boehringer Ingelheim Pharma Kg | Crystalline anticholinergic, processes for preparing it and its use for preparing a pharmaceutical composition |
BR0210537A (pt) | 2001-06-22 | 2004-06-22 | Boehringer Ingelheim Pharma | Anticolinérgico cristalino, processo para a sua preparação e sua aplicação para a preparação de um medicamento |
DE10130371A1 (de) * | 2001-06-23 | 2003-01-02 | Boehringer Ingelheim Pharma | Neue Arzneimittelkompositionen auf der Basis von Anticholinergika, Corticosteroiden und Betamimetika |
US20040126325A1 (en) * | 2002-03-12 | 2004-07-01 | David Lewis | Medicinal aerosol solution formulation products with improved chemical stability |
US7309707B2 (en) | 2002-03-20 | 2007-12-18 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Crystalline micronisate, process for the manufacture thereof and use thereof for the preparation of a medicament |
DE10212264A1 (de) | 2002-03-20 | 2003-10-02 | Boehringer Ingelheim Pharma | Kristallines Mikronisat, Verfahren zu dessen Herstellung und dessen Verwendung zur Herstellung eines Arzneimittels |
US7311894B2 (en) | 2002-03-28 | 2007-12-25 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | HFA suspension formulations containing an anticholinergic |
DE10214263A1 (de) | 2002-03-28 | 2003-10-16 | Boehringer Ingelheim Pharma | HFA-Suspensionsformulierungen enthaltend ein Anticholinergikum |
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EP1850831B1 (en) * | 2005-02-25 | 2015-12-02 | CHIESI FARMACEUTICI S.p.A. | Pharmaceutical aerosol formulations for pressurized metered dose inhalers comprising a sequestering agent |
JP2008540367A (ja) | 2005-05-02 | 2008-11-20 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 新規結晶性臭化チオトロピウム |
JP5227790B2 (ja) | 2005-05-02 | 2013-07-03 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 新規結晶性臭化チオトロピウム |
EP1896026B1 (en) | 2005-06-15 | 2013-10-09 | Boehringer Ingelheim International GmbH | Process for preparing tiotropium salts, tiotropium salts as such and pharmaceutical compositions thereof |
NZ566399A (en) | 2005-08-06 | 2011-07-29 | Boehringer Ingelheim Int | Use of tiotropium salts in the treatment of severe persistant asthma |
TWI389692B (zh) | 2005-10-10 | 2013-03-21 | Boehringer Ingelheim Int | 用以吸入β-共效劑的氣溶膠調配物 |
CN102731494A (zh) | 2005-12-19 | 2012-10-17 | 西科尔公司 | 噻托溴铵的新形式及其制备方法 |
EP1923393A1 (en) | 2006-11-17 | 2008-05-21 | Boehringer Ingelheim Pharma GmbH & Co. KG | Crystalline form of tiotropium bromide and urea |
GB0716026D0 (en) | 2007-08-16 | 2007-09-26 | Norton Healthcare Ltd | An inhalable medicament |
EP2201934A1 (en) | 2008-12-23 | 2010-06-30 | CHIESI FARMACEUTICI S.p.A. | Tiotropium aerosol formulation products with improved chemical stability |
EP2389162A1 (en) | 2009-01-26 | 2011-11-30 | Teva Pharmaceutical Industries Ltd | Processes for coating a carrier with microparticles |
DK2501363T3 (en) * | 2009-11-17 | 2015-03-23 | Cipla Ltd | inhalable |
SI2627386T1 (sl) | 2010-10-12 | 2015-10-30 | Ivax Pharmaceuticals Ireland | Nosna pršilna naprava |
GB201200525D0 (en) | 2011-12-19 | 2012-02-29 | Teva Branded Pharmaceutical Prod R & D Inc | An inhalable medicament |
GB201200504D0 (en) | 2011-12-19 | 2012-02-22 | Teva Branded Pharmaceutical Prod R & D Inc | An inhaler |
EP2819669B1 (de) | 2012-02-28 | 2021-04-21 | Boehringer Ingelheim International GmbH | Neue treibgashaltige tiotropium-formulierung |
-
2012
- 2012-01-13 GB GBGB1200525.2A patent/GB201200525D0/en not_active Ceased
- 2012-12-06 EP EP16185402.1A patent/EP3143998B1/en not_active Revoked
- 2012-12-06 PL PL12806382T patent/PL2793886T3/pl unknown
- 2012-12-06 BR BR112014014535A patent/BR112014014535A2/pt not_active Application Discontinuation
- 2012-12-06 KR KR1020147017716A patent/KR101670564B1/ko active IP Right Grant
- 2012-12-06 JP JP2014543943A patent/JP5791166B2/ja not_active Expired - Fee Related
- 2012-12-06 ES ES16185402T patent/ES2728940T3/es active Active
- 2012-12-06 TR TR2019/08429T patent/TR201908429T4/tr unknown
- 2012-12-06 PL PL16185402T patent/PL3143998T3/pl unknown
- 2012-12-06 EP EP12806382.3A patent/EP2793886B1/en not_active Revoked
- 2012-12-06 CN CN201280060763.4A patent/CN103998039A/zh active Pending
- 2012-12-06 US US14/367,031 patent/US9655969B2/en active Active
- 2012-12-06 ES ES12806382.3T patent/ES2602314T3/es active Active
- 2012-12-06 HU HUE16185402 patent/HUE044647T2/hu unknown
- 2012-12-06 KR KR1020167025194A patent/KR20160111539A/ko not_active Application Discontinuation
- 2012-12-06 AU AU2012358475A patent/AU2012358475B2/en not_active Ceased
- 2012-12-06 HU HUE12806382A patent/HUE030983T2/en unknown
- 2012-12-06 WO PCT/EP2012/074690 patent/WO2013092237A1/en active Application Filing
- 2012-12-06 EA EA201491206A patent/EA028461B1/ru not_active IP Right Cessation
- 2012-12-06 CA CA2856047A patent/CA2856047C/en not_active Expired - Fee Related
- 2012-12-06 DK DK16185402.1T patent/DK3143998T3/da active
- 2012-12-06 DK DK12806382.3T patent/DK2793886T3/en active
- 2012-12-06 MX MX2014007357A patent/MX361925B/es active IP Right Grant
- 2012-12-12 PL PL12196725T patent/PL2606891T3/pl unknown
- 2012-12-12 DK DK12196725.1T patent/DK2606891T3/en active
- 2012-12-12 EP EP12196725.1A patent/EP2606891B1/en not_active Revoked
- 2012-12-12 RS RS20140691A patent/RS53783B1/en unknown
- 2012-12-12 SI SI201230113T patent/SI2606891T1/sl unknown
- 2012-12-12 PT PT121967251T patent/PT2606891E/pt unknown
- 2012-12-12 ES ES12196725.1T patent/ES2526685T3/es active Active
- 2012-12-18 UY UY0001034525A patent/UY34525A/es not_active Application Discontinuation
- 2012-12-18 AR ARP120104795A patent/AR089302A1/es not_active Application Discontinuation
- 2012-12-19 TW TW101148516A patent/TWI468187B/zh not_active IP Right Cessation
-
2014
- 2014-04-25 ZA ZA2014/03041A patent/ZA201403041B/en unknown
- 2014-06-02 IL IL232946A patent/IL232946A0/en active IP Right Grant
- 2014-11-27 HK HK14111996.5A patent/HK1198512A1/xx unknown
- 2014-12-04 HR HRP20141176AT patent/HRP20141176T1/hr unknown
- 2014-12-19 CY CY20141101072T patent/CY1116142T1/el unknown
- 2014-12-22 SM SM201400192T patent/SMT201400192B/xx unknown
-
2015
- 2015-01-27 HK HK15100893.1A patent/HK1200343A1/xx unknown
- 2015-03-23 ZA ZA2015/01986A patent/ZA201501986B/en unknown
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