UY31776A - Derivados de la 1,3-dihidro-2h-pirrolo[3,2-b]piridin-2-ona, su preparación y sus aplicaciones en terapéutica. - Google Patents

Derivados de la 1,3-dihidro-2h-pirrolo[3,2-b]piridin-2-ona, su preparación y sus aplicaciones en terapéutica.

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Publication number
UY31776A
UY31776A UY0001031776A UY31776A UY31776A UY 31776 A UY31776 A UY 31776A UY 0001031776 A UY0001031776 A UY 0001031776A UY 31776 A UY31776 A UY 31776A UY 31776 A UY31776 A UY 31776A
Authority
UY
Uruguay
Prior art keywords
therapeutics
preparation
derived
pirrolo
piridin
Prior art date
Application number
UY0001031776A
Other languages
English (en)
Inventor
Couturier Cedric
Loic Foulon
Serradeil Legal Claudine
Gerard Valette
Original Assignee
Sanofi Aventis
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sanofi Aventis filed Critical Sanofi Aventis
Publication of UY31776A publication Critical patent/UY31776A/es

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
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Abstract

Se divulgan compuestos derivados de la 1,3-dihidro-2h-pirrolo[3,2-b]piridin-2-ona que responden a la fórmula (I), en el estado de base o de sal de adición a un ácido, que presentan una gran afinidad y una gran selectividad por los receptores V1a humanos o, para algunos compuestos, a la vez por los receptores V1a y V1b humanos de la arginina-vasopresina (A VP). Se describe su preparación y a su aplicación en terapéutica en los procesos donde participan dichos receptores.
UY0001031776A 2008-04-21 2009-04-21 Derivados de la 1,3-dihidro-2h-pirrolo[3,2-b]piridin-2-ona, su preparación y sus aplicaciones en terapéutica. UY31776A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR0802195A FR2930249B1 (fr) 2008-04-21 2008-04-21 Nouveaux derives de 3-aminoalkyl-1,3-dihydro-2h-indol-2-one, leur preparation et leur application en therapeutique.

Publications (1)

Publication Number Publication Date
UY31776A true UY31776A (es) 2009-12-14

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UY0001031776A UY31776A (es) 2008-04-21 2009-04-21 Derivados de la 1,3-dihidro-2h-pirrolo[3,2-b]piridin-2-ona, su preparación y sus aplicaciones en terapéutica.

Country Status (10)

Country Link
US (1) US8324214B2 (es)
EP (1) EP2294068B1 (es)
JP (1) JP2011518213A (es)
AR (1) AR071483A1 (es)
AT (1) ATE531715T1 (es)
CL (1) CL2009000946A1 (es)
FR (1) FR2930249B1 (es)
TW (1) TW200948811A (es)
UY (1) UY31776A (es)
WO (1) WO2009133314A1 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1434763B1 (en) * 2001-10-12 2018-01-17 Azevan Pharmaceuticals, Inc. Beta-lactamyl vasopressin v1a antagonists
JP2008534504A (ja) 2005-03-22 2008-08-28 アゼヴァン ファーマスーティカルズ，インコーポレイテッド 月経前障害を治療するためのβラクタミルアルカン酸
FR2930249B1 (fr) 2008-04-21 2010-05-14 Sanofi Aventis Nouveaux derives de 3-aminoalkyl-1,3-dihydro-2h-indol-2-one, leur preparation et leur application en therapeutique.
US9376424B2 (en) 2010-07-01 2016-06-28 Azevan Pharmaceuticals, Inc. Methods for treating post traumatic stress disorder
US9802925B2 (en) 2014-03-28 2017-10-31 Azevan Pharmaceuticals, Inc. Compositions and methods for treating neurodegenerative diseases
AU2018333051B2 (en) 2017-09-15 2024-03-21 Azevan Pharmaceuticals, Inc. Compositions and methods for treating brain injury
EA202091508A1 (ru) 2017-12-19 2020-09-14 Бристол-Маерс Сквибб Компани 6-азаиндольные соединения

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FR2665441B1 (fr) 1990-07-31 1992-12-04 Sanofi Sa Derives de la n-sulfonyl indoline, leur preparation, les compositions pharmaceutiques en contenant.
FR2708605A1 (fr) * 1993-07-30 1995-02-10 Sanofi Sa Dérivés du N-sulfonylindol-2-one, leur préparation, les compositions pharmaceutiques en contenant.
FR2686878B1 (fr) * 1992-01-30 1995-06-30 Sanofi Elf Derives du n-sulfonyl oxo-2 indole, leur preparation, les compositions pharmaceutiques en contenant.
FR2708606B1 (fr) * 1993-07-30 1995-10-27 Sanofi Sa Dérivés du N-phénylalkylindol-2-one, leur préparation, les compositions pharmaceutiques en contenant.
FR2714378B1 (fr) * 1993-12-24 1996-03-15 Sanofi Sa Dérivés de l'indol-2-one substitués en 3 par un groupe azoté, leur préparation, les compositions pharmaceutiques en contenant.
FR2740136B1 (fr) 1995-10-24 1998-01-09 Sanofi Sa Derives d'indolin-2-one, procede pour leur preparation et les compositions pharmaceutiques les contenant
FR2757157B1 (fr) 1996-12-13 1999-12-31 Sanofi Sa Derives d'indolin-2-one, procede pour leur preparation et compositions pharmaceutiques les contenant
FR2804115B1 (fr) 2000-01-25 2002-03-08 Sanofi Synthelabo Nouveaux derives de 1,3-dihydro-2h-indol-2-one, un procede pour leur preparation et les compositions pharmaceutiques en contenant
FR2804114B1 (fr) 2000-01-25 2002-03-08 Sanofi Synthelabo Nouveaux derives de 1,3-dihydro-2h-indol-2-one, un procede pour leur preparation et les compositions pharmaceutiques en contenant
FR2805536B1 (fr) 2000-02-25 2002-08-23 Sanofi Synthelabo Nouveaux derives de 1,3-dihydro-2h-indol-2-one, un procede pour leur preparation et les compositions pharmaceutiques en contenant
FR2810320B1 (fr) 2000-06-19 2002-08-23 Sanofi Synthelabo Nouveaux derives de 1,3-dihydro-2h-indol-2-one, un procede pour leur preparation et les compositions pharmaceutiques en contenant
US7015363B2 (en) 2001-07-13 2006-03-21 Kyowa Yuka Co., Ltd. Process for producing ether compound
FR2827604B1 (fr) * 2001-07-17 2003-09-19 Sanofi Synthelabo Nouveaux derives de 1-phenylsulfonyl-1,3-dihydro-2h-indol-2- one, un procede pour leur preparation et les compositions pharmaceutiques en contenant
US8030499B2 (en) * 2005-01-28 2011-10-04 Taisho Pharmaceutical Co., Ltd. 1,3-dihydro-2H-indole-2-one compound and pyrrolidine-2-one compound fused with aromatic heterocycle
DE102006040915A1 (de) 2006-08-26 2008-03-20 Abbott Gmbh & Co. Kg Substituierte Oxindol-Derivate, diese enthaltende Arzneimittel und deren Verwendung
FR2930249B1 (fr) 2008-04-21 2010-05-14 Sanofi Aventis Nouveaux derives de 3-aminoalkyl-1,3-dihydro-2h-indol-2-one, leur preparation et leur application en therapeutique.

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FR2930249B1 (fr) 2010-05-14
JP2011518213A (ja) 2011-06-23
CL2009000946A1 (es) 2010-04-09
FR2930249A1 (fr) 2009-10-23
EP2294068B1 (fr) 2011-11-02
TW200948811A (en) 2009-12-01
WO2009133314A1 (fr) 2009-11-05
US8324214B2 (en) 2012-12-04
ATE531715T1 (de) 2011-11-15
EP2294068A1 (fr) 2011-03-16
AR071483A1 (es) 2010-06-23
US20110071160A1 (en) 2011-03-24

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