UY31451A1 - Una vacuna multicomponente o monocomponente para ser utilizada contra la enfermedad de chagas, composiciones farmacéuticas que las contienen, procedimiento para la obtencion del inmunogeno de dichas vacunas y acido nucleico utilizado en dicho procedi - Google Patents
Una vacuna multicomponente o monocomponente para ser utilizada contra la enfermedad de chagas, composiciones farmacéuticas que las contienen, procedimiento para la obtencion del inmunogeno de dichas vacunas y acido nucleico utilizado en dicho procediInfo
- Publication number
- UY31451A1 UY31451A1 UY31451A UY31451A UY31451A1 UY 31451 A1 UY31451 A1 UY 31451A1 UY 31451 A UY31451 A UY 31451A UY 31451 A UY31451 A UY 31451A UY 31451 A1 UY31451 A1 UY 31451A1
- Authority
- UY
- Uruguay
- Prior art keywords
- procedure
- multicomponent
- chagas disease
- obtaining
- nucleic acid
- Prior art date
Links
- 241000223109 Trypanosoma cruzi Species 0.000 title abstract 5
- 229960005486 vaccine Drugs 0.000 title abstract 5
- 206010001935 American trypanosomiasis Diseases 0.000 title abstract 4
- 230000002163 immunogen Effects 0.000 title abstract 4
- 238000000034 method Methods 0.000 title abstract 4
- 208000024699 Chagas disease Diseases 0.000 title abstract 3
- 102000039446 nucleic acids Human genes 0.000 title abstract 2
- 108020004707 nucleic acids Proteins 0.000 title abstract 2
- 150000007523 nucleic acids Chemical class 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 2
- 208000030852 Parasitic disease Diseases 0.000 abstract 1
- 230000005875 antibody response Effects 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 230000036281 parasite infection Effects 0.000 abstract 1
- 102000040430 polynucleotide Human genes 0.000 abstract 1
- 108091033319 polynucleotide Proteins 0.000 abstract 1
- 239000002157 polynucleotide Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/002—Protozoa antigens
- A61K39/005—Trypanosoma antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/002—Protozoa antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/53—DNA (RNA) vaccination
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55505—Inorganic adjuvants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55522—Cytokines; Lymphokines; Interferons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/555—Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
- A61K2039/55511—Organic adjuvants
- A61K2039/55522—Cytokines; Lymphokines; Interferons
- A61K2039/55527—Interleukins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Peptides Or Proteins (AREA)
Abstract
Vacunas contra la enfermedad de Chagas, que consisten de una vacuna multicomponente o una vacuna monocomponente para la enfermedad del Chagas (tripanosomiasis americana) conteniendo ambas una porcion inmunogenica y uno o mas polinucleotidos que codifican a uno o mas polilétidos inmunogénicos de los Trypanosoma cruzi tal que la adminstracion de la multicomponente protege de la infeccion del parasito, lo elimina o atenua las consecuencias clínicas de dicha infeccion, y la administracion de la monocomponente estimula una respuesta de anticuerpos, de células T CD4+sesgadas Th1 o T CD8+ contra el Tripanosoma cruzi. Se incluyen las composiciones farmacéuticas que las contiene, procedimientos para la obtencion de la porcion inmunogena, y el ácido nucleico utilizado en dicho procedimiento.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| ARP070104827A AR064593A1 (es) | 2007-10-31 | 2007-10-31 | Una vacuna multicomponente o monocomponente para ser utilizada contra la enfermedad de chagas, composiciones farmaceuticas que las contienen, procedimiento para la obtencion del inmunogeno de dichas vacunas y acido nucleico utilizado en dicho procedimiento. |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UY31451A1 true UY31451A1 (es) | 2009-05-29 |
Family
ID=40591558
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UY31451A UY31451A1 (es) | 2007-10-31 | 2008-10-31 | Una vacuna multicomponente o monocomponente para ser utilizada contra la enfermedad de chagas, composiciones farmacéuticas que las contienen, procedimiento para la obtencion del inmunogeno de dichas vacunas y acido nucleico utilizado en dicho procedi |
Country Status (18)
| Country | Link |
|---|---|
| US (3) | US8900598B2 (es) |
| EP (1) | EP2206513B1 (es) |
| AR (1) | AR064593A1 (es) |
| BR (1) | BRPI0805753A2 (es) |
| CA (1) | CA2702534C (es) |
| CO (1) | CO6280407A2 (es) |
| CR (1) | CR11334A (es) |
| DO (1) | DOP2010000083A (es) |
| EC (1) | ECSP10010055A (es) |
| ES (1) | ES2569943T3 (es) |
| GT (1) | GT201000066A (es) |
| HN (1) | HN2010000750A (es) |
| MX (1) | MX2010004626A (es) |
| NI (1) | NI201000071A (es) |
| PA (1) | PA8816401A1 (es) |
| PE (2) | PE20091161A1 (es) |
| UY (1) | UY31451A1 (es) |
| WO (1) | WO2009056965A2 (es) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR064593A1 (es) * | 2007-10-31 | 2009-04-15 | Baeremaecker Barros Carlos De | Una vacuna multicomponente o monocomponente para ser utilizada contra la enfermedad de chagas, composiciones farmaceuticas que las contienen, procedimiento para la obtencion del inmunogeno de dichas vacunas y acido nucleico utilizado en dicho procedimiento. |
| WO2011031317A2 (en) * | 2009-09-10 | 2011-03-17 | The Board Of Regents Of The University Of Texas System | Vaccine for control of trypanosoma cruzi infection and chagas disease |
| WO2013011184A2 (es) * | 2011-07-21 | 2013-01-24 | Consejo Superior De Investigaciones Científicas (Csic) | Molécula quimerica util en inmunoterapia frente a la leishmaniosis, que comprende un fragmento de la proteina pfr1 de leishmania infantum con epitopes especificos inmunodominantes |
| US10279023B2 (en) | 2013-09-24 | 2019-05-07 | Board Of Regents, The University Of Texas System | Mucin-associated surface protein as a vaccine against chagas disease |
| US9566320B2 (en) | 2013-09-24 | 2017-02-14 | The Board Of Regents Of The University Of Texas System | Mucin-associated surface protein as vaccine against Chagas disease |
| WO2016209598A1 (en) * | 2015-06-23 | 2016-12-29 | Saint Louis University | Peptides for inducing chagas disease responses |
| BR102021010469A2 (pt) * | 2021-05-28 | 2022-12-13 | Fundação Oswaldo Cruz | Proteína quimérica recombinante, seu uso, e, composição |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0586687A4 (en) | 1992-03-25 | 1996-04-17 | Univ New York | Trans-sialidase and methods of use and making thereof |
| US6875584B1 (en) * | 1999-03-02 | 2005-04-05 | University Of Georgia Research Foundation, Inc. | Prophylactic and therapeutic immunization against protozoan infection and disease |
| US7060676B2 (en) * | 1999-12-20 | 2006-06-13 | Trustees Of Tufts College | T. cruzi-derived neurotrophic agents and methods of use therefor |
| US7780969B2 (en) * | 2005-07-15 | 2010-08-24 | University Of Georgia Research Foundation, Inc. | Trypanosoma cruzi proteome compositions and methods |
| BRPI0709560A2 (pt) | 2006-03-17 | 2011-07-19 | Vib Vzw | uso de uma proteìna mutante de trans-sialidade de trypanosoma enzimaticamente inativa, e composição farmacêutica |
| AR064593A1 (es) * | 2007-10-31 | 2009-04-15 | Baeremaecker Barros Carlos De | Una vacuna multicomponente o monocomponente para ser utilizada contra la enfermedad de chagas, composiciones farmaceuticas que las contienen, procedimiento para la obtencion del inmunogeno de dichas vacunas y acido nucleico utilizado en dicho procedimiento. |
-
2007
- 2007-10-31 AR ARP070104827A patent/AR064593A1/es unknown
-
2008
- 2008-10-30 MX MX2010004626A patent/MX2010004626A/es active IP Right Grant
- 2008-10-30 ES ES08844056.5T patent/ES2569943T3/es active Active
- 2008-10-30 CA CA2702534A patent/CA2702534C/en not_active Expired - Fee Related
- 2008-10-30 PE PE2008001858A patent/PE20091161A1/es not_active Application Discontinuation
- 2008-10-30 EP EP08844056.5A patent/EP2206513B1/en not_active Not-in-force
- 2008-10-30 PE PE2013002770A patent/PE20140520A1/es active IP Right Grant
- 2008-10-30 WO PCT/IB2008/002923 patent/WO2009056965A2/es active Application Filing
- 2008-10-30 US US12/740,393 patent/US8900598B2/en not_active Expired - Fee Related
- 2008-10-31 UY UY31451A patent/UY31451A1/es not_active Application Discontinuation
- 2008-10-31 BR BRPI0805753-2A patent/BRPI0805753A2/pt not_active Application Discontinuation
-
2009
- 2009-02-19 PA PA20098816401A patent/PA8816401A1/es unknown
-
2010
- 2010-03-15 DO DO2010000083A patent/DOP2010000083A/es unknown
- 2010-03-23 GT GT201000066A patent/GT201000066A/es unknown
- 2010-03-24 CR CR11334A patent/CR11334A/es unknown
- 2010-03-26 EC EC2010010055A patent/ECSP10010055A/es unknown
- 2010-04-21 HN HN2010000750A patent/HN2010000750A/es unknown
- 2010-04-26 NI NI201000071A patent/NI201000071A/es unknown
- 2010-05-18 CO CO10058905A patent/CO6280407A2/es unknown
-
2014
- 2014-10-31 US US14/529,454 patent/US9662378B2/en not_active Expired - Fee Related
-
2017
- 2017-04-20 US US15/492,365 patent/US10213500B2/en active Active
Also Published As
| Publication number | Publication date |
|---|---|
| MX2010004626A (es) | 2010-10-04 |
| EP2206513B1 (en) | 2016-02-17 |
| CR11334A (es) | 2010-05-26 |
| WO2009056965A3 (es) | 2009-07-23 |
| US10213500B2 (en) | 2019-02-26 |
| GT201000066A (es) | 2012-04-03 |
| US9662378B2 (en) | 2017-05-30 |
| PE20140520A1 (es) | 2014-05-05 |
| US20150056243A1 (en) | 2015-02-26 |
| BRPI0805753A2 (pt) | 2012-04-17 |
| NI201000071A (es) | 2010-11-10 |
| PE20091161A1 (es) | 2009-08-28 |
| CO6280407A2 (es) | 2011-05-20 |
| US20100297186A1 (en) | 2010-11-25 |
| EP2206513A2 (en) | 2010-07-14 |
| ECSP10010055A (es) | 2010-06-29 |
| DOP2010000083A (es) | 2010-07-15 |
| US8900598B2 (en) | 2014-12-02 |
| WO2009056965A2 (es) | 2009-05-07 |
| ES2569943T3 (es) | 2016-05-13 |
| CA2702534C (en) | 2016-10-18 |
| PA8816401A1 (es) | 2009-09-17 |
| US20170290896A1 (en) | 2017-10-12 |
| CA2702534A1 (en) | 2009-05-07 |
| HN2010000750A (es) | 2013-08-19 |
| AR064593A1 (es) | 2009-04-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| UY31451A1 (es) | Una vacuna multicomponente o monocomponente para ser utilizada contra la enfermedad de chagas, composiciones farmacéuticas que las contienen, procedimiento para la obtencion del inmunogeno de dichas vacunas y acido nucleico utilizado en dicho procedi | |
| CY1122181T1 (el) | Φαρμακοτεχνικη μορφη αντισωματος | |
| BR112016010383A2 (pt) | compostos de pyy seletivos e usos dos mesmos | |
| CO2020001960A2 (es) | Formulaciones de anticuerpos anti-c5 de alta concentración | |
| CO2021003931A2 (es) | Dosis unitaria de vacuna contra el dengue y administración de esta | |
| AR104984A1 (es) | Compuestos selectivos para pyy y sus usos | |
| AR064009A1 (es) | Metodo de inmunizacion contra los 4 serotipos del dengue | |
| PE20100145A1 (es) | Vacunas contra la coccidiosis | |
| DOP2010000188A (es) | Una vacuna de vih que comprende una proteina y un agente estabilizador | |
| BR112014001409A2 (pt) | métodos e composições para vacinação contra staphylococcus aureus | |
| CY1124505T1 (el) | Κρυσταλλικες μορφες βιλαστινης και μεθοδοι παρασκευης αυτων | |
| BR112014031386A2 (pt) | vacinas para meningococos do sorogrupo x | |
| BR112014027885A2 (pt) | produção de ingredientes farmacêuticos ativos estéreis | |
| MA42317B2 (fr) | Composition de vaccin combinée pour administration multiple | |
| BR112016025977A2 (pt) | composições, métodos e utilizações para formulações de papilomavirus humano estábulo estável | |
| AR086491A1 (es) | Composicion farmaceutica que comprende fexofenadina | |
| AR076479A1 (es) | Composiciones farmaceuticas para terapias de mantenimiento que contienen como ingrediente activo un anticuerpo que reconoce el antigeno leucocitario humano (hla) de clase i | |
| AR087811A1 (es) | Vacuna contra el staphylococcus aureus | |
| BR112013027006A2 (pt) | método de produzir substâncias com gás supersaturado, dispositivo de distribuição transdérmica do mesmo | |
| CO2022002493A2 (es) | Nanoemulsion de ácido 18p-glicirretínico | |
| CO6280495A2 (es) | Vacuna que contiene un extracto de proteina ribosoma (rpe) y opcionalmente un adyuvante que estimula las th1 | |
| Primozic et al. | Using facial laser scanning for assessing facial symmetry: a prospective study in children affected by crossbite | |
| AR107295A1 (es) | Administración intradérmica de una composición de inmunoglobulina g | |
| CL2022000590A1 (es) | Métodos para mejorar la fusión vertebral con abaloparatida | |
| Leite et al. | Emotional exhaustion and immune response to influenza vaccine: is there any influence? |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 105 | Application deemed to be withdrawn (no grant fee paid) |
Effective date: 20201126 |