UY31420A1 - Arilindenopirimidinas y su uso como antagonistas del receptor a2a de adenosina - Google Patents
Arilindenopirimidinas y su uso como antagonistas del receptor a2a de adenosinaInfo
- Publication number
- UY31420A1 UY31420A1 UY31420A UY31420A UY31420A1 UY 31420 A1 UY31420 A1 UY 31420A1 UY 31420 A UY31420 A UY 31420A UY 31420 A UY31420 A UY 31420A UY 31420 A1 UY31420 A1 UY 31420A1
- Authority
- UY
- Uruguay
- Prior art keywords
- arylindenopirimidins
- adenosine
- antagonists
- receiver
- arylindenopyrimidine
- Prior art date
Links
- OIRDTQYFTABQOQ-KQYNXXCUSA-N adenosine Chemical compound C1=NC=2C(N)=NC=NC=2N1[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O OIRDTQYFTABQOQ-KQYNXXCUSA-N 0.000 title 2
- 239000002126 C01EB10 - Adenosine Substances 0.000 title 1
- 229960005305 adenosine Drugs 0.000 title 1
- 239000005557 antagonist Substances 0.000 title 1
- 208000018737 Parkinson disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000000069 prophylactic effect Effects 0.000 abstract 1
- 230000001225 therapeutic effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Addiction (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US98224707P | 2007-10-24 | 2007-10-24 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UY31420A1 true UY31420A1 (es) | 2009-04-30 |
Family
ID=40091927
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UY31420A UY31420A1 (es) | 2007-10-24 | 2008-10-24 | Arilindenopirimidinas y su uso como antagonistas del receptor a2a de adenosina |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US8017614B2 (https=) |
| EP (1) | EP2217575A1 (https=) |
| JP (1) | JP2011500819A (https=) |
| CN (1) | CN101835759A (https=) |
| AR (1) | AR069009A1 (https=) |
| AU (1) | AU2008317034A1 (https=) |
| CL (1) | CL2008003131A1 (https=) |
| PA (1) | PA8801501A1 (https=) |
| PE (1) | PE20091344A1 (https=) |
| TW (1) | TW200934493A (https=) |
| UY (1) | UY31420A1 (https=) |
| WO (1) | WO2009055308A1 (https=) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20110105540A1 (en) * | 2009-10-29 | 2011-05-05 | Jackson Paul F | 2-AMINO-9-[4-(4-METHOXY-PHENOXY)-PIPERIDIN-1-YL]-4-PHENYL-INDENO[1,2-D]PYRIMIDIN-5-ONE AND ITS USE AS A HIGHLY SELECTIVE ADENOSINE A2a RECEPTOR ANTAGONIST |
| GB2497476B (en) * | 2010-09-06 | 2018-01-10 | Guangzhou Inst Biomed & Health | Amide Compounds |
| AU2013251079B2 (en) | 2012-04-20 | 2017-03-23 | Ucb Pharma S.A. | Methods for treating Parkinson's disease |
| US20200345725A1 (en) | 2019-01-11 | 2020-11-05 | Omeros Corporation | Methods and Compositions for Treating Cancer |
| CN119173276A (zh) | 2022-04-13 | 2024-12-20 | 吉利德科学公司 | 用于治疗表达Trop-2的癌症的组合疗法 |
| WO2025137640A1 (en) | 2023-12-22 | 2025-06-26 | Gilead Sciences, Inc. | Azaspiro wrn inhibitors |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040127510A1 (en) | 2002-04-16 | 2004-07-01 | Heintzelman Geoffrey R. | Arylindenopyridines and arylindenopyrimidines and related therapeutic and prophylactic methods |
| ATE429421T1 (de) | 2003-10-03 | 2009-05-15 | Ortho Mcneil Pharm Inc | Arylindenopyridin- und arylindenopyrimidinverbindungen und ihre verwendung als adenosin-a2a-rezeptor antagonisten |
-
2008
- 2008-10-17 WO PCT/US2008/080256 patent/WO2009055308A1/en not_active Ceased
- 2008-10-17 AU AU2008317034A patent/AU2008317034A1/en not_active Abandoned
- 2008-10-17 JP JP2010531141A patent/JP2011500819A/ja not_active Withdrawn
- 2008-10-17 CN CN200880112882A patent/CN101835759A/zh active Pending
- 2008-10-17 EP EP08841238A patent/EP2217575A1/en not_active Withdrawn
- 2008-10-17 US US12/253,358 patent/US8017614B2/en not_active Expired - Fee Related
- 2008-10-23 PA PA20088801501A patent/PA8801501A1/es unknown
- 2008-10-23 PE PE2008001819A patent/PE20091344A1/es not_active Application Discontinuation
- 2008-10-23 AR ARP080104625A patent/AR069009A1/es not_active Application Discontinuation
- 2008-10-23 CL CL2008003131A patent/CL2008003131A1/es unknown
- 2008-10-23 TW TW097140560A patent/TW200934493A/zh unknown
- 2008-10-24 UY UY31420A patent/UY31420A1/es unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP2217575A1 (en) | 2010-08-18 |
| US8017614B2 (en) | 2011-09-13 |
| WO2009055308A1 (en) | 2009-04-30 |
| AR069009A1 (es) | 2009-12-23 |
| TW200934493A (en) | 2009-08-16 |
| US20090111827A1 (en) | 2009-04-30 |
| JP2011500819A (ja) | 2011-01-06 |
| CL2008003131A1 (es) | 2010-02-19 |
| PE20091344A1 (es) | 2009-09-24 |
| PA8801501A1 (es) | 2009-05-15 |
| AU2008317034A1 (en) | 2009-04-30 |
| CN101835759A (zh) | 2010-09-15 |
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