UY30324A1 - Proteinas de fusion del rage, formulaciones y métodos de uso - Google Patents
Proteinas de fusion del rage, formulaciones y métodos de usoInfo
- Publication number
- UY30324A1 UY30324A1 UY30324A UY30324A UY30324A1 UY 30324 A1 UY30324 A1 UY 30324A1 UY 30324 A UY30324 A UY 30324A UY 30324 A UY30324 A UY 30324A UY 30324 A1 UY30324 A1 UY 30324A1
- Authority
- UY
- Uruguay
- Prior art keywords
- rage
- fusion proteins
- rage fusion
- formulations
- methods
- Prior art date
Links
- 102000037865 fusion proteins Human genes 0.000 title abstract 6
- 108020001507 fusion proteins Proteins 0.000 title abstract 6
- 239000000203 mixture Substances 0.000 title abstract 3
- 229920001184 polypeptide Polymers 0.000 abstract 3
- 102000004196 processed proteins & peptides Human genes 0.000 abstract 3
- 108090000765 processed proteins & peptides Proteins 0.000 abstract 3
- 238000009472 formulation Methods 0.000 abstract 2
- 108060003951 Immunoglobulin Proteins 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000012634 fragment Substances 0.000 abstract 1
- 102000018358 immunoglobulin Human genes 0.000 abstract 1
- 239000003446 ligand Substances 0.000 abstract 1
- 230000001404 mediated effect Effects 0.000 abstract 1
- 230000007170 pathology Effects 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
- C07K14/70503—Immunoglobulin superfamily
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/02—Nasal agents, e.g. decongestants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/08—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease
- A61P19/10—Drugs for skeletal disorders for bone diseases, e.g. rachitism, Paget's disease for osteoporosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/62—DNA sequences coding for fusion proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/30—Non-immunoglobulin-derived peptide or protein having an immunoglobulin constant or Fc region, or a fragment thereof, attached thereto
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Biomedical Technology (AREA)
- Immunology (AREA)
- Molecular Biology (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Microbiology (AREA)
- Plant Pathology (AREA)
- Physics & Mathematics (AREA)
- Physical Education & Sports Medicine (AREA)
- Diabetes (AREA)
- Rheumatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Vascular Medicine (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Cardiology (AREA)
- Cell Biology (AREA)
- Urology & Nephrology (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US79845506P | 2006-05-05 | 2006-05-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| UY30324A1 true UY30324A1 (es) | 2008-01-02 |
Family
ID=38521887
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| UY30324A UY30324A1 (es) | 2006-05-05 | 2007-05-04 | Proteinas de fusion del rage, formulaciones y métodos de uso |
Country Status (21)
| Country | Link |
|---|---|
| US (2) | US7981424B2 (OSRAM) |
| EP (2) | EP2380983A3 (OSRAM) |
| JP (1) | JP5558810B2 (OSRAM) |
| KR (1) | KR20090008459A (OSRAM) |
| CN (1) | CN101548012A (OSRAM) |
| AR (1) | AR060862A1 (OSRAM) |
| AU (1) | AU2007248784B2 (OSRAM) |
| BR (1) | BRPI0711193A2 (OSRAM) |
| CA (1) | CA2651348A1 (OSRAM) |
| DO (1) | DOP2007000089A (OSRAM) |
| EA (1) | EA017291B1 (OSRAM) |
| IL (1) | IL194482A0 (OSRAM) |
| MX (1) | MX2008013863A (OSRAM) |
| NL (1) | NL2000626A1 (OSRAM) |
| NZ (1) | NZ571692A (OSRAM) |
| PE (1) | PE20080397A1 (OSRAM) |
| SG (1) | SG171670A1 (OSRAM) |
| TW (1) | TW200801036A (OSRAM) |
| UY (1) | UY30324A1 (OSRAM) |
| WO (1) | WO2007130302A2 (OSRAM) |
| ZA (1) | ZA200809394B (OSRAM) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AP2007003869A0 (en) * | 2004-08-03 | 2007-02-28 | Transtech Pharma Inc | Rage fusion proteins and methods of use |
| UA92154C2 (ru) * | 2004-08-03 | 2010-10-11 | Транстек Фарма, Инк. | Rage-слитые белки и способы их применения |
| ES2431632T3 (es) * | 2005-12-23 | 2013-11-27 | Gcoder Systems Ab | Patrón de posicionamiento |
| WO2007094926A2 (en) * | 2006-02-09 | 2007-08-23 | Transtech Pharma, Inc. | Rage fusion proteins and methods of use |
| US7981424B2 (en) | 2006-05-05 | 2011-07-19 | Transtech Pharma, Inc. | RAGE fusion proteins, formulations, and methods of use thereof |
| WO2008100470A2 (en) * | 2007-02-15 | 2008-08-21 | Transtech Pharma, Inc. | Rage - immunoglobulin fusion proteins |
| JP5241518B2 (ja) * | 2007-02-15 | 2013-07-17 | 国立大学法人九州大学 | 抗hmgb−1抗体を含む間質性肺疾患治療剤 |
| TW200902063A (en) | 2007-02-15 | 2009-01-16 | Univ Kumamoto | Therapeutic agent comprising antibody capable of specifically binding to human hmgb-1 as active ingredient |
| EP2123298A4 (en) * | 2007-02-15 | 2011-09-28 | Univ Fukuoka | AGENT FOR SUPPRESSING REJECTION IN AN ORGAN TRANSPLANT COMPRISING ANTI-HMGB-1 ANTIBODY |
| KR101361355B1 (ko) | 2007-06-14 | 2014-02-12 | 갈락티카 파마슈티칼스, 인크. | Rage 융합 단백질 |
| EP2421892A1 (en) | 2009-04-20 | 2012-02-29 | Pfizer Inc. | Control of protein glycosylation and compositions and methods relating thereto |
| WO2011102845A1 (en) * | 2010-02-18 | 2011-08-25 | Transtech Pharma, Inc. | Rage fusion protein compositions and methods of use |
| US9345770B2 (en) | 2011-11-16 | 2016-05-24 | University of Pittsburgh—of the Commonwealth System of Higher Education | Immunogenic tumor associated stromal cell antigen peptides and methods of their use |
| DK2925338T3 (da) * | 2012-11-28 | 2019-05-06 | Nono Inc | Frysetørret formulering af tat-nr2b9c |
| US10251935B2 (en) | 2012-11-28 | 2019-04-09 | Nono Inc. | Lyophilized formulation comprising tat-NR2B9C, histidine and trehalose |
| US10191033B2 (en) | 2013-12-05 | 2019-01-29 | The Broad Institute, Inc. | Biomarkers for detecting pre-cachexia or cachexia and methods of treatment thereof |
| WO2016051808A1 (ja) * | 2014-10-01 | 2016-04-07 | 国立研究開発法人農業・食品産業技術総合研究機構 | 遺伝子組換えカイコにより生産したビオチン化酸化ldl受容体・終末糖化産物受容体 |
| EP3822291A1 (en) | 2015-06-10 | 2021-05-19 | The Broad Institute Inc. | Antibodies, compounds and screens for identifying and treating cachexia or pre-cachexia |
| US11111296B2 (en) | 2015-12-14 | 2021-09-07 | The Broad Institute, Inc. | Compositions and methods for treating cardiac dysfunction |
| CN112699601B (zh) * | 2020-12-28 | 2022-05-31 | 电子科技大学 | 一种传感器网络数据的空时重构方法 |
| US20230246158A1 (en) * | 2022-02-02 | 2023-08-03 | Enevate Corporation | Cycle life in si/li batteries using high temperature deep discharge cycling |
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| CA2146559A1 (en) | 1992-10-23 | 1994-05-11 | Melanie K. Spriggs | Methods of preparing soluble, oligomeric proteins |
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| WO2005021710A2 (en) * | 2003-06-02 | 2005-03-10 | University Of Miami | Chimeric molecules and methods of use |
| AU2004270207A1 (en) * | 2003-09-05 | 2005-03-17 | The Trustees Of Columbia University In The City Of New York | RAGE-related methods and compositions for treating glomerular injury |
| WO2005042032A1 (en) * | 2003-10-31 | 2005-05-12 | The Trustees Of Columbia University In The City Of New York | Methods for treating multiple sclerosis |
| US20060012414A1 (en) * | 2004-07-15 | 2006-01-19 | Texas Instruments Incorporated | Circuit and method for generating a polyphase clock signal and system incorporating the same |
| EP1771565B1 (en) * | 2004-07-20 | 2012-09-05 | The Feinstein Institute for Medical Research | Rage protein derivatives |
| US20060040354A1 (en) | 2004-07-20 | 2006-02-23 | O'keefe Theresa L | Novel polyadenylation signal for use in expression vectors |
| AP2007003869A0 (en) * | 2004-08-03 | 2007-02-28 | Transtech Pharma Inc | Rage fusion proteins and methods of use |
| UA92154C2 (ru) * | 2004-08-03 | 2010-10-11 | Транстек Фарма, Инк. | Rage-слитые белки и способы их применения |
| US20060084145A1 (en) * | 2004-09-27 | 2006-04-20 | Anderson Glenn M | sRAGE mimetibody, compositions, methods and uses |
| US20080207499A1 (en) * | 2005-06-29 | 2008-08-28 | Gaetano Barile | Rage-related methods for treating and preventing diabetic retinopathy |
| WO2007094926A2 (en) * | 2006-02-09 | 2007-08-23 | Transtech Pharma, Inc. | Rage fusion proteins and methods of use |
| US7981424B2 (en) | 2006-05-05 | 2011-07-19 | Transtech Pharma, Inc. | RAGE fusion proteins, formulations, and methods of use thereof |
| WO2008100470A2 (en) * | 2007-02-15 | 2008-08-21 | Transtech Pharma, Inc. | Rage - immunoglobulin fusion proteins |
-
2007
- 2007-04-25 US US11/789,637 patent/US7981424B2/en not_active Expired - Fee Related
- 2007-04-25 WO PCT/US2007/010125 patent/WO2007130302A2/en not_active Ceased
- 2007-04-25 BR BRPI0711193-2A patent/BRPI0711193A2/pt not_active IP Right Cessation
- 2007-04-25 KR KR1020087029731A patent/KR20090008459A/ko not_active Withdrawn
- 2007-04-25 EP EP11167432A patent/EP2380983A3/en not_active Withdrawn
- 2007-04-25 NZ NZ571692A patent/NZ571692A/en not_active IP Right Cessation
- 2007-04-25 MX MX2008013863A patent/MX2008013863A/es active IP Right Grant
- 2007-04-25 CA CA002651348A patent/CA2651348A1/en not_active Abandoned
- 2007-04-25 JP JP2009509615A patent/JP5558810B2/ja not_active Expired - Fee Related
- 2007-04-25 EA EA200870502A patent/EA017291B1/ru not_active IP Right Cessation
- 2007-04-25 AU AU2007248784A patent/AU2007248784B2/en not_active Ceased
- 2007-04-25 EP EP07794379A patent/EP2021474A2/en not_active Withdrawn
- 2007-04-25 CN CNA200780018207XA patent/CN101548012A/zh active Pending
- 2007-04-25 SG SG201103296-8A patent/SG171670A1/en unknown
- 2007-05-04 DO DO2007000089A patent/DOP2007000089A/es unknown
- 2007-05-04 PE PE2007000550A patent/PE20080397A1/es not_active Application Discontinuation
- 2007-05-04 NL NL2000626A patent/NL2000626A1/nl not_active IP Right Cessation
- 2007-05-04 UY UY30324A patent/UY30324A1/es not_active Application Discontinuation
- 2007-05-04 AR ARP070101949A patent/AR060862A1/es not_active Application Discontinuation
- 2007-05-04 TW TW096115905A patent/TW200801036A/zh unknown
-
2008
- 2008-10-02 IL IL194482A patent/IL194482A0/en unknown
- 2008-11-03 ZA ZA200809394A patent/ZA200809394B/xx unknown
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2011
- 2011-06-13 US US13/158,748 patent/US8344120B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| US20080045455A1 (en) | 2008-02-21 |
| NL2000626A1 (nl) | 2007-11-06 |
| AU2007248784A1 (en) | 2007-11-15 |
| CA2651348A1 (en) | 2007-11-15 |
| US8344120B2 (en) | 2013-01-01 |
| KR20090008459A (ko) | 2009-01-21 |
| EA017291B1 (ru) | 2012-11-30 |
| SG171670A1 (en) | 2011-06-29 |
| US7981424B2 (en) | 2011-07-19 |
| ZA200809394B (en) | 2009-07-29 |
| CN101548012A (zh) | 2009-09-30 |
| BRPI0711193A2 (pt) | 2013-06-18 |
| PE20080397A1 (es) | 2008-04-28 |
| JP2009536201A (ja) | 2009-10-08 |
| AU2007248784B2 (en) | 2013-11-21 |
| EP2021474A2 (en) | 2009-02-11 |
| WO2007130302A3 (en) | 2008-04-03 |
| US20110282035A1 (en) | 2011-11-17 |
| NZ571692A (en) | 2012-01-12 |
| EA200870502A1 (ru) | 2009-06-30 |
| IL194482A0 (en) | 2011-08-01 |
| MX2008013863A (es) | 2008-11-14 |
| AR060862A1 (es) | 2008-07-16 |
| TW200801036A (en) | 2008-01-01 |
| EP2380983A3 (en) | 2012-12-05 |
| JP5558810B2 (ja) | 2014-07-23 |
| DOP2007000089A (es) | 2007-11-15 |
| WO2007130302A2 (en) | 2007-11-15 |
| EP2380983A2 (en) | 2011-10-26 |
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