UY28339A1 - Derivados de 2-amino-piridina utiles para el tratamiento de enfermedades - Google Patents
Derivados de 2-amino-piridina utiles para el tratamiento de enfermedadesInfo
- Publication number
- UY28339A1 UY28339A1 UY28339A UY28339A UY28339A1 UY 28339 A1 UY28339 A1 UY 28339A1 UY 28339 A UY28339 A UY 28339A UY 28339 A UY28339 A UY 28339A UY 28339 A1 UY28339 A1 UY 28339A1
- Authority
- UY
- Uruguay
- Prior art keywords
- diseases
- amino
- treatment
- pyridine derivatives
- disorders
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/73—Unsubstituted amino or imino radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
Abstract
La invención se refiere a compuestos de fórmula (1) y a procedimientos para prepara, a intermedios usados en la preparación de, a composiciones que los contienen y a los usos de dichos derivados. Los compuestos de acuerdo con la presente invención sen útiles en numerosas enfermedades, trastornos y afecciones, en particular enfermedades, trastornos y afecciones inflamatorias, alérgicas y respiratorias.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GBGB0312832.9A GB0312832D0 (en) | 2003-06-04 | 2003-06-04 | 2-amino-pyridine derivatives useful for the treatment of diseases |
Publications (1)
Publication Number | Publication Date |
---|---|
UY28339A1 true UY28339A1 (es) | 2005-01-31 |
Family
ID=9959308
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UY28339A UY28339A1 (es) | 2003-06-04 | 2004-06-02 | Derivados de 2-amino-piridina utiles para el tratamiento de enfermedades |
Country Status (18)
Country | Link |
---|---|
EP (1) | EP1633715B1 (es) |
JP (1) | JP2006526613A (es) |
AR (1) | AR044475A1 (es) |
AT (1) | ATE372321T1 (es) |
BR (1) | BRPI0410946A (es) |
CA (1) | CA2527788A1 (es) |
CL (1) | CL2004001366A1 (es) |
DE (1) | DE602004008773T2 (es) |
ES (1) | ES2291882T3 (es) |
GB (1) | GB0312832D0 (es) |
GT (1) | GT200400116A (es) |
MX (1) | MXPA05012840A (es) |
NL (1) | NL1026329C2 (es) |
PA (1) | PA8604301A1 (es) |
PE (1) | PE20050628A1 (es) |
TW (1) | TW200524603A (es) |
UY (1) | UY28339A1 (es) |
WO (1) | WO2004108676A1 (es) |
Families Citing this family (56)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB0411056D0 (en) | 2004-05-18 | 2004-06-23 | Novartis Ag | Organic compounds |
PE20060272A1 (es) | 2004-05-24 | 2006-05-22 | Glaxo Group Ltd | (2r,3r,4s,5r,2'r,3'r,4's,5's)-2,2'-{trans-1,4-ciclohexanodiilbis-[imino(2-{[2-(1-metil-1h-imidazol-4-il)etil]amino}-9h-purin-6,9-diil)]}bis[5-(2-etil-2h-tetrazol-5-il)tetrahidro-3,4-furanodiol] como agonista a2a |
UA87854C2 (en) * | 2004-06-07 | 2009-08-25 | Мерк Энд Ко., Инк. | N-(2-benzyl)-2-phenylbutanamides as androgen receptor modulators |
AR051090A1 (es) | 2004-09-20 | 2006-12-20 | Xenon Pharmaceuticals Inc | Derivados heterociclicos y su uso como inhibidores de la estearoil-coa desaturasa |
AR051094A1 (es) | 2004-09-20 | 2006-12-20 | Xenon Pharmaceuticals Inc | Derivados heterociclicos y su uso como inhibidores de la estearoil-coa desaturasa |
EP1830837B1 (en) | 2004-09-20 | 2013-09-04 | Xenon Pharmaceuticals Inc. | Heterocyclic derivatives for the treatment of diseases mediated by stearoyl-coa desaturase enzymes |
BRPI0515482A (pt) | 2004-09-20 | 2008-07-22 | Xenon Pharmaceuticals Inc | derivados heterocìclicos e seus usos como agentes terapêuticos |
MX2007003325A (es) | 2004-09-20 | 2007-06-05 | Xenon Pharmaceuticals Inc | Derivados heterociclicos y su uso como inhibidores estearoil-coa-desaturasa. |
AU2005286648A1 (en) | 2004-09-20 | 2006-03-30 | Xenon Pharmaceuticals Inc. | Heterocyclic derivatives and their use as stearoyl-CoA desaturase inhibitors |
AU2005286728A1 (en) | 2004-09-20 | 2006-03-30 | Xenon Pharmaceuticals Inc. | Heterocyclic derivatives and their use as mediators of stearoyl-CoA desaturase |
GT200500281A (es) | 2004-10-22 | 2006-04-24 | Novartis Ag | Compuestos organicos. |
GB0424284D0 (en) | 2004-11-02 | 2004-12-01 | Novartis Ag | Organic compounds |
GB0426164D0 (en) | 2004-11-29 | 2004-12-29 | Novartis Ag | Organic compounds |
JP2009513563A (ja) | 2005-06-03 | 2009-04-02 | ゼノン・ファーマシューティカルズ・インコーポレイテッド | ヒトのステアロイル−CoAデサチュラーゼ阻害剤としてのアミノチアゾール誘導体 |
GB0514809D0 (en) | 2005-07-19 | 2005-08-24 | Glaxo Group Ltd | Compounds |
GB0516313D0 (en) | 2005-08-08 | 2005-09-14 | Argenta Discovery Ltd | Azole derivatives and their uses |
US7994211B2 (en) | 2005-08-08 | 2011-08-09 | Argenta Discovery Limited | Bicyclo[2.2.1]hept-7-ylamine derivatives and their uses |
RU2421464C2 (ru) | 2005-10-21 | 2011-06-20 | Новартис Аг | Человеческие антитела к il-13 и их терапевтическое применение |
GB0601951D0 (en) | 2006-01-31 | 2006-03-15 | Novartis Ag | Organic compounds |
BRPI0710573A2 (pt) | 2006-04-21 | 2012-02-28 | Novartis Ag | compostos orgánicos, usos e processos para a preparação dos referidos compostos, bem como composição farmacêutica compreendendo os mesmos |
WO2007146869A1 (en) * | 2006-06-09 | 2007-12-21 | Parion Sciences, Inc. | Phenyl substituted pyrazinoylguanidine sodium channel blockers possessing beta agonist activity |
JP5483880B2 (ja) | 2006-10-23 | 2014-05-07 | 武田薬品工業株式会社 | イミノピリジン誘導体およびその用途 |
NZ580737A (en) | 2007-05-07 | 2012-03-30 | Novartis Ag | Organic compound |
PT2444120T (pt) | 2007-12-10 | 2018-01-03 | Novartis Ag | Análogos da amilorida espirocíclicos como bloqueadores de enac |
ES2442930T3 (es) | 2008-01-11 | 2014-02-14 | Novartis Ag | Pirimidinas como inhibidores de cinasas |
US8481569B2 (en) | 2008-04-23 | 2013-07-09 | Takeda Pharmaceutical Company Limited | Iminopyridine derivatives and use thereof |
MX2010013675A (es) | 2008-06-10 | 2011-02-15 | Novartis Ag | Derivados de pirazina como bloqueadores del canal de sodio epitelial. |
US8236786B2 (en) | 2008-08-07 | 2012-08-07 | Pulmagen Therapeutics (Inflammation) Limited | Respiratory disease treatment |
DE102008049675A1 (de) | 2008-09-30 | 2010-04-01 | Markus Dr. Heinrich | Verfahren zur Herstellung von 3-Aminobiphenylen |
DK2379507T3 (da) | 2008-12-30 | 2014-01-27 | Pulmagen Therapeutics Inflammation Ltd | Sulfonamidforbindelser til behandling af åndedrætsforstyrrelser |
WO2010150014A1 (en) | 2009-06-24 | 2010-12-29 | Pulmagen Therapeutics (Inflammation) Limited | 5r- 5 -deuterated glitazones for respiratory disease treatment |
WO2011050325A1 (en) | 2009-10-22 | 2011-04-28 | Vertex Pharmaceuticals Incorporated | Compositions for treatment of cystic fibrosis and other chronic diseases |
GB0918922D0 (en) | 2009-10-28 | 2009-12-16 | Vantia Ltd | Aminopyridine derivatives |
GB0918924D0 (en) | 2009-10-28 | 2009-12-16 | Vantia Ltd | Azaindole derivatives |
GB0918923D0 (en) | 2009-10-28 | 2009-12-16 | Vantia Ltd | Aminothiazole derivatives |
WO2011098746A1 (en) | 2010-02-09 | 2011-08-18 | Pulmagen Therapeutics (Inflammation) Limited | Crystalline acid addition salts of ( 5r) -enanti0mer of pioglitazone |
GB201002224D0 (en) | 2010-02-10 | 2010-03-31 | Argenta Therapeutics Ltd | Respiratory disease treatment |
GB201002243D0 (en) | 2010-02-10 | 2010-03-31 | Argenta Therapeutics Ltd | Respiratory disease treatment |
US8247436B2 (en) | 2010-03-19 | 2012-08-21 | Novartis Ag | Pyridine and pyrazine derivative for the treatment of CF |
UY33597A (es) | 2010-09-09 | 2012-04-30 | Irm Llc | Compuestos y composiciones como inhibidores de la trk |
WO2012034095A1 (en) | 2010-09-09 | 2012-03-15 | Irm Llc | Compounds and compositions as trk inhibitors |
US8372845B2 (en) | 2010-09-17 | 2013-02-12 | Novartis Ag | Pyrazine derivatives as enac blockers |
PE20140378A1 (es) | 2011-02-25 | 2014-03-28 | Irm Llc | Compuestos y composiciones como inhibidores de la trk |
US8883819B2 (en) | 2011-09-01 | 2014-11-11 | Irm Llc | Bicyclic heterocycle derivatives for the treatment of pulmonary arterial hypertension |
WO2013038390A1 (en) | 2011-09-16 | 2013-03-21 | Novartis Ag | N-substituted heterocyclyl carboxamides |
WO2013038378A1 (en) | 2011-09-16 | 2013-03-21 | Novartis Ag | Pyridine amide derivatives |
WO2013038381A1 (en) | 2011-09-16 | 2013-03-21 | Novartis Ag | Pyridine/pyrazine amide derivatives |
WO2013038373A1 (en) | 2011-09-16 | 2013-03-21 | Novartis Ag | Pyridine amide derivatives |
JP5886433B2 (ja) | 2011-09-16 | 2016-03-16 | ノバルティス アーゲー | 嚢胞性線維症処置のためのヘテロ環式化合物 |
US8809340B2 (en) | 2012-03-19 | 2014-08-19 | Novartis Ag | Crystalline form |
US9073921B2 (en) | 2013-03-01 | 2015-07-07 | Novartis Ag | Salt forms of bicyclic heterocyclic derivatives |
CN106458966B (zh) | 2014-04-24 | 2019-05-07 | 诺华股份有限公司 | 作为磷脂酰肌醇3-激酶抑制剂的吡嗪衍生物 |
JP6454727B2 (ja) | 2014-04-24 | 2019-01-16 | ノバルティス アーゲー | ホスファチジルイノシトール3−キナーゼ阻害薬としてのアミノピリジン誘導体 |
EP3134397A1 (en) | 2014-04-24 | 2017-03-01 | Novartis AG | Amino pyrazine derivatives as phosphatidylinositol 3-kinase inhibitors |
KR20220019015A (ko) | 2019-06-10 | 2022-02-15 | 노파르티스 아게 | Cf, copd, 및 기관지확장증 치료를 위한 피리딘 및 피라진 유도체 |
BR112022002569A2 (pt) | 2019-08-28 | 2022-07-19 | Novartis Ag | Derivados de 1,3-fenil heteroarila substituídos e seu uso no tratamento de doenças |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4358455A (en) * | 1980-12-23 | 1982-11-09 | Merck & Co., Inc. | Aralkylamindethanol heterocyclic compounds |
CA2220399A1 (en) * | 1995-05-10 | 1996-11-14 | Pfizer Inc. | .beta.-adrenergic agonists |
ES2228413T3 (es) * | 1999-07-23 | 2005-04-16 | Pfizer Products Inc. | Productos intermedios y un procedimiento para producir agonistas de receptores beta-adrenergicos. |
TWI249515B (en) * | 2001-11-13 | 2006-02-21 | Theravance Inc | Aryl aniline beta2 adrenergic receptor agonists |
GB0217225D0 (en) * | 2002-07-25 | 2002-09-04 | Glaxo Group Ltd | Medicinal compounds |
ATE392206T1 (de) * | 2002-10-11 | 2008-05-15 | Pfizer | Indolderivate als beta-2 agonisten |
-
2003
- 2003-06-04 GB GBGB0312832.9A patent/GB0312832D0/en not_active Ceased
-
2004
- 2004-06-01 CA CA002527788A patent/CA2527788A1/en not_active Abandoned
- 2004-06-01 JP JP2006508431A patent/JP2006526613A/ja not_active Withdrawn
- 2004-06-01 DE DE602004008773T patent/DE602004008773T2/de not_active Expired - Fee Related
- 2004-06-01 ES ES04735621T patent/ES2291882T3/es active Active
- 2004-06-01 EP EP04735621A patent/EP1633715B1/en not_active Not-in-force
- 2004-06-01 PE PE2004000553A patent/PE20050628A1/es not_active Application Discontinuation
- 2004-06-01 BR BRPI0410946-5A patent/BRPI0410946A/pt not_active IP Right Cessation
- 2004-06-01 AT AT04735621T patent/ATE372321T1/de not_active IP Right Cessation
- 2004-06-01 WO PCT/IB2004/001850 patent/WO2004108676A1/en active IP Right Grant
- 2004-06-01 MX MXPA05012840A patent/MXPA05012840A/es unknown
- 2004-06-02 UY UY28339A patent/UY28339A1/es not_active Application Discontinuation
- 2004-06-03 CL CL200401366A patent/CL2004001366A1/es unknown
- 2004-06-03 NL NL1026329A patent/NL1026329C2/nl not_active IP Right Cessation
- 2004-06-03 GT GT200400116A patent/GT200400116A/es unknown
- 2004-06-03 AR ARP040101904A patent/AR044475A1/es unknown
- 2004-06-03 PA PA20048604301A patent/PA8604301A1/es unknown
- 2004-06-03 TW TW093115990A patent/TW200524603A/zh unknown
Also Published As
Publication number | Publication date |
---|---|
PE20050628A1 (es) | 2005-08-30 |
DE602004008773T2 (de) | 2008-01-10 |
AR044475A1 (es) | 2005-09-14 |
GB0312832D0 (en) | 2003-07-09 |
GT200400116A (es) | 2005-03-03 |
ES2291882T3 (es) | 2008-03-01 |
JP2006526613A (ja) | 2006-11-24 |
PA8604301A1 (es) | 2004-12-16 |
WO2004108676A1 (en) | 2004-12-16 |
BRPI0410946A (pt) | 2006-06-27 |
MXPA05012840A (es) | 2006-02-13 |
CA2527788A1 (en) | 2004-12-16 |
EP1633715B1 (en) | 2007-09-05 |
ATE372321T1 (de) | 2007-09-15 |
NL1026329A1 (nl) | 2004-12-07 |
DE602004008773D1 (de) | 2007-10-18 |
TW200524603A (en) | 2005-08-01 |
EP1633715A1 (en) | 2006-03-15 |
CL2004001366A1 (es) | 2005-05-06 |
NL1026329C2 (nl) | 2005-07-26 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
UY28339A1 (es) | Derivados de 2-amino-piridina utiles para el tratamiento de enfermedades | |
CR8649A (es) | Derivados de formamidina para el tratamiento de enfermedades | |
UY28343A1 (es) | Derivados de 2-amino-piridina utiles para el tratamiento de enfermedades | |
ECSP056164A (es) | Compuestos utiles para el tratamiento de enfermedades | |
UY28724A1 (es) | Derivados de sulfonamida para el tratamiento de enfermedades | |
UY28721A1 (es) | Derivados de sulfonamida para eltratamiento de enfermedades | |
PA8627001A1 (es) | Compuestos para el tratamiento de enfermedades | |
PA8586001A1 (es) | Derivados de indol útiles para el tratamiento de enfermedades | |
AR059963A1 (es) | Derivados de amina | |
CR10700A (es) | Derivados de sulfonamida | |
EA200601462A1 (ru) | Соединения для лечения заболеваний | |
CR8636A (es) | Compuestos utiles para el tratamiento de enfermedades | |
UY28819A1 (es) | Derivados de formamida para el tratamiento de enfermedades | |
DOP2004000921A (es) | Derivados de 2-amino-piridina utiles para el tratamiento de enfermedades | |
DOP2005000043A (es) | Compuestos para el tratamiento de enfermedades | |
UY28810A1 (es) | Compuestos utiles para el tratamiento de enfermedades | |
DOP2004000902A (es) | Compuestos utiles para el tratamiento de enfermedades | |
UY28816A1 (es) | Compuestos para el tratamiento de enfermedades | |
CR8513A (es) | Derivados de sulfonamida para el tratamiento de enfermedades | |
DOP2005000037A (es) | Compuestos utiles para el tratamiento de enfermedades | |
CR9838A (es) | Derivados de sulfonamida para el tratamiento de enfermedades | |
DOP2005000041A (es) | Compuestos para el tratamientos de enfermandades | |
CU23532B7 (es) | Derivados de sulfonamida para el tratamiento de enfermedades | |
CU23537B7 (es) | Derivados de sulfonamida para el tratamiento de enfermedades | |
CR8514A (es) | Derivados de sulfonamida para el tratamiento de enfermedades |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
109 | Application deemed to be withdrawn |
Effective date: 20150522 |