UY26852A1 - Utilización de dihidropiridinas condensadas para la preparación de agentes destinados al tratamiento de dolores crónicos - Google Patents

Utilización de dihidropiridinas condensadas para la preparación de agentes destinados al tratamiento de dolores crónicos

Info

Publication number
UY26852A1
UY26852A1 UY26852A UY26852A UY26852A1 UY 26852 A1 UY26852 A1 UY 26852A1 UY 26852 A UY26852 A UY 26852A UY 26852 A UY26852 A UY 26852A UY 26852 A1 UY26852 A1 UY 26852A1
Authority
UY
Uruguay
Prior art keywords
condensed
preparation
treatment
chronic pain
dihydropiridins
Prior art date
Application number
UY26852A
Other languages
English (en)
Inventor
Dr Wolfram Gaida
Dr Dietrich Arndts
Dr Walter Loser
Dr Klaus Klinder
Dr Stefan Matthias Blech
Dr Hennig Draheim
Original Assignee
Boehringer Ingelheim Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma
Publication of UY26852A1 publication Critical patent/UY26852A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4365—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system having sulfur as a ring hetero atom, e.g. ticlopidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4747—Quinolines; Isoquinolines spiro-condensed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
    • C07D217/16—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals substituted by oxygen atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

El invento se refiere a la utilización de dihidropiridinas condensadas y sus sales con ácidos fisiológicamente compatibles para la preparación de agentes destinados al tratamiento de dolores crónicos, de la Fórmula general I, en la que A es benzo o tieno, y Z, R1, R2, R3, R4, R5 y R6 son como se han definido en la memoria descriptiva, así como nuevos compuestos de la Fórmula I.
UY26852A 2000-07-25 2001-07-25 Utilización de dihidropiridinas condensadas para la preparación de agentes destinados al tratamiento de dolores crónicos UY26852A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10035997A DE10035997A1 (de) 2000-07-25 2000-07-25 Verwendung von anellierten Dihydropyridinen zur Herstellung von Mitteln für die Behandlung von chronischen Schmerzen

Publications (1)

Publication Number Publication Date
UY26852A1 true UY26852A1 (es) 2002-02-28

Family

ID=7650021

Family Applications (1)

Application Number Title Priority Date Filing Date
UY26852A UY26852A1 (es) 2000-07-25 2001-07-25 Utilización de dihidropiridinas condensadas para la preparación de agentes destinados al tratamiento de dolores crónicos

Country Status (5)

Country Link
AR (1) AR029981A1 (es)
AU (1) AU2001289719A1 (es)
DE (1) DE10035997A1 (es)
UY (1) UY26852A1 (es)
WO (1) WO2002007714A2 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003014089A1 (en) * 2001-07-31 2003-02-20 Virginia Commonwealth University Aminotetrahydroisoquinoline derivatives as analgesics
RU2711646C1 (ru) * 2019-04-08 2020-01-17 Федеральное государственное бюджетное учреждение науки Институт молекулярной генетики Российской академии наук Синтез меченного тритием 6,7-диметокси-4,4-диметил-1-[4-(4-трифторметилфенокси)фенил]-3Н-изохинолина

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1386076A (en) * 1971-06-03 1975-03-05 Wyeth John & Brother Ltd Isoquinoline derivatives
PH25651A (en) * 1986-05-21 1991-08-21 Duphar Int Res New di, tetrahydroisoquinoline derivatives
GB8921304D0 (en) * 1989-09-20 1989-11-08 Wyeth John & Brother Ltd New method of treatment and heterocyclic compounds used therein
WO1992011242A1 (en) * 1990-12-17 1992-07-09 Shell Internationale Research Maatschappij B.V. Fungicidal isoquinoline derivatives
WO2000044725A1 (de) * 1999-01-28 2000-08-03 Boehringer Ingelheim Pharma Kg Anellierte dihydropyridine und verwendung von anellierten dihydropyridinen für die herstellung von mitteln für die behandlung von epilepsie

Also Published As

Publication number Publication date
WO2002007714A2 (en) 2002-01-31
DE10035997A1 (de) 2002-02-07
WO2002007714A3 (en) 2002-09-06
AU2001289719A1 (en) 2002-02-05
AR029981A1 (es) 2003-07-23

Similar Documents

Publication Publication Date Title
CR6726A (es) Compuestos azapoliciclicos condensados con arilo
DOP2006000084A (es) Compuestos sulfoximino-macrociclicos y sus sales, composiciones farmaceuticas que comprenden dichos compuestos, metodos de preparacion y usos de los mismos
UY27258A1 (es) Derivados de dihidro-benzo b 1, 4 diazepin-2-ona como antagonistas ii mglur2
CR7017A (es) Carboxamidas como fungicidas en agricultura
AR047529A1 (es) Compuestos de quinolina sustituidos
BRPI0407950A (pt) processo para a preparação de uma composição de higiene pessoal
BR0017026A (pt) Lipeptìdeos como agentes antibacterianos
GT200100137A (es) Pro-drogas de derivados de 4-fenil-piridina.
UY28040A1 (es) Antagonistas de cgrp elegidos, procedimiento para su preparación, así como su empleo como medicamentos.
UY30274A1 (es) Derivados sustituidos de la n-(4-metil-1,3-tiazol-2-il)guanidina, formulaciones farmacéuticas conteniéndolo y aplicaciones
ECSP034796A (es) DERIVADOS DIHIDRO-BENZO[b][1,4]DIAZEPIN-2-ONA ANTAGONISTAS I MGLUR2
SE0200979D0 (sv) New compounds
DK1353911T3 (da) Antivirale midler
BR0111358A (pt) Compostos de tioacetamida e seu uso
AR027967A1 (es) Derivados de esteres de pirazol como agentes antinflamatorios/analgesicos
GT200100148A (es) Derivados de 4-fenil-piridina.
SE9901077D0 (sv) Novel use
AR021843A1 (es) Derivados de propanolamina sustituidos con heterociclos, procedimiento para su preparacion, y su utilizacion.
UY27418A1 (es) Formulaciones en combinación de derivados de propanol-amina sustituidos con arilo, junto con otras sustancias activas y su utilización
BR9916807A (pt) Antagonistas de 5ht1 para terapia antidepressiva
ECSP044971A (es) Isoxazolopiridinonas y su uso en el tratamiento de enfermedad de parkinson
HN2002000050A (es) Compuestos farmaceuticamente activos
UY26852A1 (es) Utilización de dihidropiridinas condensadas para la preparación de agentes destinados al tratamiento de dolores crónicos
BR0009194A (pt) Composição do resorcinol
BRPI0411208A (pt) uso de derivados 2-amino-1,3-propanodiol para a fabricação de um medicamento para o tratamento de vários tipos de dor

Legal Events

Date Code Title Description
109 Application deemed to be withdrawn

Effective date: 20140513