UY26852A1 - Utilización de dihidropiridinas condensadas para la preparación de agentes destinados al tratamiento de dolores crónicos - Google Patents

Utilización de dihidropiridinas condensadas para la preparación de agentes destinados al tratamiento de dolores crónicos

Info

Publication number
UY26852A1
UY26852A1 UY26852A UY26852A UY26852A1 UY 26852 A1 UY26852 A1 UY 26852A1 UY 26852 A UY26852 A UY 26852A UY 26852 A UY26852 A UY 26852A UY 26852 A1 UY26852 A1 UY 26852A1
Authority
UY
Uruguay
Prior art keywords
condensed
preparation
treatment
chronic pain
dihydropiridins
Prior art date
Application number
UY26852A
Other languages
English (en)
Inventor
Dr Wolfram Gaida
Dr Dietrich Arndts
Dr Walter Loser
Dr Klaus Klinder
Dr Stefan Matthias Blech
Dr Hennig Draheim
Original Assignee
Boehringer Ingelheim Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma
Publication of UY26852A1 publication Critical patent/UY26852A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4365—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system having sulfur as a ring hetero atom, e.g. ticlopidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4747—Quinolines; Isoquinolines spiro-condensed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
    • C07D217/16—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals substituted by oxygen atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

El invento se refiere a la utilización de dihidropiridinas condensadas y sus sales con ácidos fisiológicamente compatibles para la preparación de agentes destinados al tratamiento de dolores crónicos, de la Fórmula general I, en la que A es benzo o tieno, y Z, R1, R2, R3, R4, R5 y R6 son como se han definido en la memoria descriptiva, así como nuevos compuestos de la Fórmula I.
UY26852A 2000-07-25 2001-07-25 Utilización de dihidropiridinas condensadas para la preparación de agentes destinados al tratamiento de dolores crónicos UY26852A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10035997A DE10035997A1 (de) 2000-07-25 2000-07-25 Verwendung von anellierten Dihydropyridinen zur Herstellung von Mitteln für die Behandlung von chronischen Schmerzen

Publications (1)

Publication Number Publication Date
UY26852A1 true UY26852A1 (es) 2002-02-28

Family

ID=7650021

Family Applications (1)

Application Number Title Priority Date Filing Date
UY26852A UY26852A1 (es) 2000-07-25 2001-07-25 Utilización de dihidropiridinas condensadas para la preparación de agentes destinados al tratamiento de dolores crónicos

Country Status (5)

Country Link
AR (1) AR029981A1 (es)
AU (1) AU2001289719A1 (es)
DE (1) DE10035997A1 (es)
UY (1) UY26852A1 (es)
WO (1) WO2002007714A2 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003014089A1 (en) * 2001-07-31 2003-02-20 Virginia Commonwealth University Aminotetrahydroisoquinoline derivatives as analgesics
RU2711646C1 (ru) * 2019-04-08 2020-01-17 Федеральное государственное бюджетное учреждение науки Институт молекулярной генетики Российской академии наук Синтез меченного тритием 6,7-диметокси-4,4-диметил-1-[4-(4-трифторметилфенокси)фенил]-3Н-изохинолина

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1386076A (en) * 1971-06-03 1975-03-05 Wyeth John & Brother Ltd Isoquinoline derivatives
CA1330560C (en) * 1986-05-21 1994-07-05 Maurits E. A. Vandewalle Di- and tetrahydroisoquinoline derivatives
GB8921304D0 (en) * 1989-09-20 1989-11-08 Wyeth John & Brother Ltd New method of treatment and heterocyclic compounds used therein
KR930703259A (ko) * 1990-12-17 1993-11-29 알베르투스 빌헬무스 요아네스 쩨스트라텐 살균성 이소퀴놀린 유도체
WO2000044725A1 (de) * 1999-01-28 2000-08-03 Boehringer Ingelheim Pharma Kg Anellierte dihydropyridine und verwendung von anellierten dihydropyridinen für die herstellung von mitteln für die behandlung von epilepsie

Also Published As

Publication number Publication date
AR029981A1 (es) 2003-07-23
AU2001289719A1 (en) 2002-02-05
DE10035997A1 (de) 2002-02-07
WO2002007714A2 (en) 2002-01-31
WO2002007714A3 (en) 2002-09-06

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Legal Events

Date Code Title Description
109 Application deemed to be withdrawn

Effective date: 20140513