UY26852A1 - USE OF CONDENSED DIHYDROPIRIDINS FOR THE PREPARATION OF AGENTS INTENDED FOR THE TREATMENT OF CHRONIC PAIN - Google Patents

USE OF CONDENSED DIHYDROPIRIDINS FOR THE PREPARATION OF AGENTS INTENDED FOR THE TREATMENT OF CHRONIC PAIN

Info

Publication number
UY26852A1
UY26852A1 UY26852A UY26852A UY26852A1 UY 26852 A1 UY26852 A1 UY 26852A1 UY 26852 A UY26852 A UY 26852A UY 26852 A UY26852 A UY 26852A UY 26852 A1 UY26852 A1 UY 26852A1
Authority
UY
Uruguay
Prior art keywords
condensed
preparation
treatment
chronic pain
dihydropiridins
Prior art date
Application number
UY26852A
Other languages
Spanish (es)
Inventor
Dr Wolfram Gaida
Dr Dietrich Arndts
Dr Walter Loser
Dr Klaus Klinder
Dr Stefan Matthias Blech
Dr Hennig Draheim
Original Assignee
Boehringer Ingelheim Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharma filed Critical Boehringer Ingelheim Pharma
Publication of UY26852A1 publication Critical patent/UY26852A1/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4365—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system having sulfur as a ring hetero atom, e.g. ticlopidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4747—Quinolines; Isoquinolines spiro-condensed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
    • C07D217/16—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals substituted by oxygen atoms

Abstract

El invento se refiere a la utilización de dihidropiridinas condensadas y sus sales con ácidos fisiológicamente compatibles para la preparación de agentes destinados al tratamiento de dolores crónicos, de la Fórmula general I, en la que A es benzo o tieno, y Z, R1, R2, R3, R4, R5 y R6 son como se han definido en la memoria descriptiva, así como nuevos compuestos de la Fórmula I.The invention relates to the use of condensed dihydropyridines and their salts with physiologically compatible acids for the preparation of agents for the treatment of chronic pain, of the general Formula I, in which A is benzo or thieno, and Z, R1, R2 , R3, R4, R5 and R6 are as defined in the specification, as well as new compounds of Formula I.

UY26852A 2000-07-25 2001-07-25 USE OF CONDENSED DIHYDROPIRIDINS FOR THE PREPARATION OF AGENTS INTENDED FOR THE TREATMENT OF CHRONIC PAIN UY26852A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10035997A DE10035997A1 (en) 2000-07-25 2000-07-25 Use of fused dihydropyridines for the manufacture of agents for the treatment of chronic pain

Publications (1)

Publication Number Publication Date
UY26852A1 true UY26852A1 (en) 2002-02-28

Family

ID=7650021

Family Applications (1)

Application Number Title Priority Date Filing Date
UY26852A UY26852A1 (en) 2000-07-25 2001-07-25 USE OF CONDENSED DIHYDROPIRIDINS FOR THE PREPARATION OF AGENTS INTENDED FOR THE TREATMENT OF CHRONIC PAIN

Country Status (5)

Country Link
AR (1) AR029981A1 (en)
AU (1) AU2001289719A1 (en)
DE (1) DE10035997A1 (en)
UY (1) UY26852A1 (en)
WO (1) WO2002007714A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003014089A1 (en) * 2001-07-31 2003-02-20 Virginia Commonwealth University Aminotetrahydroisoquinoline derivatives as analgesics
RU2711646C1 (en) * 2019-04-08 2020-01-17 Федеральное государственное бюджетное учреждение науки Институт молекулярной генетики Российской академии наук Synthesis of tritium-labeled 6,7-dimethoxy-4,4-dimethyl-1-[4-(4-trifluoromethylphenoxy)phenyl]-3n-isoquinoline

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1386076A (en) * 1971-06-03 1975-03-05 Wyeth John & Brother Ltd Isoquinoline derivatives
CA1330560C (en) * 1986-05-21 1994-07-05 Maurits E. A. Vandewalle Di- and tetrahydroisoquinoline derivatives
GB8921304D0 (en) * 1989-09-20 1989-11-08 Wyeth John & Brother Ltd New method of treatment and heterocyclic compounds used therein
KR930703259A (en) * 1990-12-17 1993-11-29 알베르투스 빌헬무스 요아네스 쩨스트라텐 Disinfectant Isoquinoline Derivatives
WO2000044725A1 (en) * 1999-01-28 2000-08-03 Boehringer Ingelheim Pharma Kg Fused dihydropyridines and use of fused dihydropyridines in the preparation of agents for the treatment of epilepsy

Also Published As

Publication number Publication date
AU2001289719A1 (en) 2002-02-05
WO2002007714A2 (en) 2002-01-31
AR029981A1 (en) 2003-07-23
WO2002007714A3 (en) 2002-09-06
DE10035997A1 (en) 2002-02-07

Similar Documents

Publication Publication Date Title
CR6726A (en) AZAPOLICICLIC COMPOUNDS CONDENSED WITH ARILO
DOP2006000084A (en) SULFOXIMINO-MACROCICLIC COMPOUNDS AND THEIR SALTS, PHARMACEUTICAL COMPOSITIONS THAT INCLUDE SUCH COMPOUNDS, PREPARATION METHODS AND USES OF THE SAME
UY27258A1 (en) DERIVATIVES OF DIHIDRO-BENZO B 1, 4 DIAZEPIN-2-ONA AS ANTAGONISTS II MGLUR2
CR7017A (en) CARBOXAMIDS AS FUNGICIDES IN AGRICULTURE
AR047529A1 (en) SUBSTITUTED QUINOLINE COMPOUNDS
BR0017026A (en) Lipeptides as antibacterial agents
GT200100137A (en) PRO-DRUGS OF 4-PHENYL-PYRIDINE DERIVATIVES.
UY30274A1 (en) SUBSTITUTED DERIVATIVES OF THE N- (4-METHYL-1,3-TIAZOL-2-IL) GUANIDINE, PHARMACEUTICAL FORMULATIONS CONTAINING IT AND APPLICATIONS
ECSP034796A (en) DIHIDRO-BENZO DERIVATIVES [b] [1,4] DIAZEPIN-2-ONA ANTAGONISTS I MGLUR2
CR10165A (en) "USE OF BENZO-FUSION HETEROCICLE SULFAMIDE DERIVATIVES FOR DEPRESSION TREATMENT"
BR0111358A (en) Thioacetamide compounds and their use
UY28848A1 (en) SELECTED CGRP ANTAGONISTS, PROCEDURES FOR THEIR PREPARATION, AND THEIR EMPLOYMENT AS MEDICATIONS
BR0016467A (en) Lipopeptides as antibacterial agents
AR022469A1 (en) USE OF SUBSTITUTED AND DERIVATIVE ISOXAZOLCARBOXILIC ACIDS AND NEW SUBSTANCES
GT200100148A (en) DERIVATIVES OF 4-PHENYL-PYRIDINE.
SE9901077D0 (en) Novel use
AR021843A1 (en) DERIVATIVES OF PROPANOLAMINE SUBSTITUTED WITH HETEROCICLES, PROCEDURE FOR THEIR PREPARATION, AND ITS USE.
UY27418A1 (en) FORMULATIONS IN COMBINATION OF PROPANOL-AMINA DERIVATIVES SUBSTITUTED WITH ARILO, TOGETHER WITH OTHER ACTIVE SUBSTANCES AND THEIR USE
BR9916807A (en) 5ht1 antagonists for antidepressant therapy
DE60112960D1 (en) CONDENSED PYRIDOINDOL DERIVATIVES
ECSP044971A (en) ISOXAZOLOPIRIDINONAS AND ITS USE IN PARKINSON'S DISEASE TREATMENT
HN2002000050A (en) PHARMACEUTICALLY ACTIVE COMPOUNDS
UY26852A1 (en) USE OF CONDENSED DIHYDROPIRIDINS FOR THE PREPARATION OF AGENTS INTENDED FOR THE TREATMENT OF CHRONIC PAIN
BR0009194A (en) Composition of resorcinol
BRPI0411208A (en) use of 2-amino-1,3-propanediol derivatives for the manufacture of a medicament for the treatment of various types of pain

Legal Events

Date Code Title Description
109 Application deemed to be withdrawn

Effective date: 20140513