AR029981A1 - USE OF CONDENSED DIHYDROPIRIDINES FOR THE PREPARATION OF AGENTS INTENDED FOR THE TREATMENT OF CHRONIC PAIN - Google Patents

USE OF CONDENSED DIHYDROPIRIDINES FOR THE PREPARATION OF AGENTS INTENDED FOR THE TREATMENT OF CHRONIC PAIN

Info

Publication number
AR029981A1
AR029981A1 ARP010103543A ARP010103543A AR029981A1 AR 029981 A1 AR029981 A1 AR 029981A1 AR P010103543 A ARP010103543 A AR P010103543A AR P010103543 A ARP010103543 A AR P010103543A AR 029981 A1 AR029981 A1 AR 029981A1
Authority
AR
Argentina
Prior art keywords
condensed
preparation
treatment
chronic pain
dihydropiridines
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Suspension/Interruption
Application number
ARP010103543A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim Pharma GmbH Co KG
Original Assignee
Boehringer Ingelheim Pharma GmbH Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Pharma GmbH Co KG filed Critical Boehringer Ingelheim Pharma GmbH Co KG
Publication of AR029981A1 publication Critical patent/AR029981A1/en
Suspension/Interruption legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/4353—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/4365—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom ortho- or peri-condensed with heterocyclic ring systems the heterocyclic ring system having sulfur as a ring hetero atom, e.g. ticlopidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/47—Quinolines; Isoquinolines
    • A61K31/4747—Quinolines; Isoquinolines spiro-condensed
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
    • C07D217/16—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals substituted by oxygen atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

El presente se refiere a la utilizacion de dihidropiridinas condensadas y sus sales con ácidos fisiologicamente compatibles para la preparacion de agentes destinados al tratamiento de dolores cronicos, de la formula general (1), en la que A es benzo o tieno; y Z, R1, R2, R3, R4, R5 y R6 son como se han definido en la memoria descriptiva, así como nuevos compuestos de la formula (1).This refers to the use of condensed dihydropyridines and their salts with physiologically compatible acids for the preparation of agents intended for the treatment of chronic pain, of the general formula (1), in which A is benzo or thieno; and Z, R1, R2, R3, R4, R5 and R6 are as defined in the specification, as well as new compounds of the formula (1).

ARP010103543A 2000-07-25 2001-07-25 USE OF CONDENSED DIHYDROPIRIDINES FOR THE PREPARATION OF AGENTS INTENDED FOR THE TREATMENT OF CHRONIC PAIN Suspension/Interruption AR029981A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE10035997A DE10035997A1 (en) 2000-07-25 2000-07-25 Use of fused dihydropyridines for the manufacture of agents for the treatment of chronic pain

Publications (1)

Publication Number Publication Date
AR029981A1 true AR029981A1 (en) 2003-07-23

Family

ID=7650021

Family Applications (1)

Application Number Title Priority Date Filing Date
ARP010103543A Suspension/Interruption AR029981A1 (en) 2000-07-25 2001-07-25 USE OF CONDENSED DIHYDROPIRIDINES FOR THE PREPARATION OF AGENTS INTENDED FOR THE TREATMENT OF CHRONIC PAIN

Country Status (5)

Country Link
AR (1) AR029981A1 (en)
AU (1) AU2001289719A1 (en)
DE (1) DE10035997A1 (en)
UY (1) UY26852A1 (en)
WO (1) WO2002007714A2 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003014089A1 (en) * 2001-07-31 2003-02-20 Virginia Commonwealth University Aminotetrahydroisoquinoline derivatives as analgesics
RU2711646C1 (en) * 2019-04-08 2020-01-17 Федеральное государственное бюджетное учреждение науки Институт молекулярной генетики Российской академии наук Synthesis of tritium-labeled 6,7-dimethoxy-4,4-dimethyl-1-[4-(4-trifluoromethylphenoxy)phenyl]-3n-isoquinoline

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1386076A (en) * 1971-06-03 1975-03-05 Wyeth John & Brother Ltd Isoquinoline derivatives
CA1330560C (en) * 1986-05-21 1994-07-05 Maurits E. A. Vandewalle Di- and tetrahydroisoquinoline derivatives
GB8921304D0 (en) * 1989-09-20 1989-11-08 Wyeth John & Brother Ltd New method of treatment and heterocyclic compounds used therein
KR930703259A (en) * 1990-12-17 1993-11-29 알베르투스 빌헬무스 요아네스 쩨스트라텐 Disinfectant Isoquinoline Derivatives
WO2000044725A1 (en) * 1999-01-28 2000-08-03 Boehringer Ingelheim Pharma Kg Fused dihydropyridines and use of fused dihydropyridines in the preparation of agents for the treatment of epilepsy

Also Published As

Publication number Publication date
AU2001289719A1 (en) 2002-02-05
DE10035997A1 (en) 2002-02-07
WO2002007714A2 (en) 2002-01-31
WO2002007714A3 (en) 2002-09-06
UY26852A1 (en) 2002-02-28

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Legal Events

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