UY24666A1 - Derivado analgesico/antiinflamatorio no ulcerogenico de clonixina - Google Patents

Derivado analgesico/antiinflamatorio no ulcerogenico de clonixina

Info

Publication number
UY24666A1
UY24666A1 UY24666A UY24666A UY24666A1 UY 24666 A1 UY24666 A1 UY 24666A1 UY 24666 A UY24666 A UY 24666A UY 24666 A UY24666 A UY 24666A UY 24666 A1 UY24666 A1 UY 24666A1
Authority
UY
Uruguay
Prior art keywords
analgesic
clonixin
ulcerogenic
inflammatory
derivative
Prior art date
Application number
UY24666A
Other languages
English (en)
Inventor
Gustavo Aldoma Dr
Susana Elida Piatti Dra
Original Assignee
Handforth Investiments Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Handforth Investiments Ltd filed Critical Handforth Investiments Ltd
Publication of UY24666A1 publication Critical patent/UY24666A1/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/80—Acids; Esters in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pain & Pain Management (AREA)
  • Animal Behavior & Ethology (AREA)
  • Rheumatology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyridine Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)

Abstract

Un derivado de clonixina o cloxinato de 4-nitroxibutilo, es un nuevo producto analgésico-antiinflamatorio no esteroideo, que tiene un equilibrio extraordinariamente bueno entre una alta actividad analgesica/antiinflamatoria y bajos efectos adversos ulcerogénicos, principalmente como una consecuencia de una sorprendentemente alta actividad antiinflamatoria.
UY24666A 1996-08-16 1997-08-12 Derivado analgesico/antiinflamatorio no ulcerogenico de clonixina UY24666A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP1996/003610 WO1998007701A1 (en) 1996-08-16 1996-08-16 Non-ulcerogenic analgesic/anti-inflammatory clonixin derivative

Publications (1)

Publication Number Publication Date
UY24666A1 true UY24666A1 (es) 1998-02-03

Family

ID=8166287

Family Applications (1)

Application Number Title Priority Date Filing Date
UY24666A UY24666A1 (es) 1996-08-16 1997-08-12 Derivado analgesico/antiinflamatorio no ulcerogenico de clonixina

Country Status (9)

Country Link
JP (1) JP2000516235A (es)
AU (1) AU714258B2 (es)
BR (1) BR9612730A (es)
CA (1) CA2262788A1 (es)
CO (1) CO4900065A1 (es)
PE (1) PE99398A1 (es)
TW (1) TW337521B (es)
UY (1) UY24666A1 (es)
WO (1) WO1998007701A1 (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20030042935A (ko) * 2001-11-26 2003-06-02 알앤피코리아 주식회사 클로닉신리신 제제
ITMI20021861A1 (it) * 2002-08-29 2004-02-29 Nicox Sa Procedimento di sintesi di nitrossialchilesteri di acidi carbossilici, intermedi impiegabili in detto procedimento e loro preparazione.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4273777A (en) * 1979-06-04 1981-06-16 Laboratorios Bago S.A. Methods of treating mammals suffering from inflammation and pain
IT1256345B (it) * 1992-08-20 1995-12-01 Esteri nitrici di derivati dell'acido 2-(2,6-di-alo-fenilammino) fenilacetico e procedimento per la loro preparazione

Also Published As

Publication number Publication date
AU6924996A (en) 1998-03-06
BR9612730A (pt) 1999-08-24
TW337521B (en) 1998-08-01
AU714258B2 (en) 1999-12-23
JP2000516235A (ja) 2000-12-05
WO1998007701A1 (en) 1998-02-26
CA2262788A1 (en) 1998-02-26
PE99398A1 (es) 1999-01-25
CO4900065A1 (es) 2000-03-27

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