TW337521B - Non-ulcerogenic analgesic/anti-inflammatory cloixin derivative - Google Patents

Non-ulcerogenic analgesic/anti-inflammatory cloixin derivative

Info

Publication number
TW337521B
TW337521B TW085110724A TW85110724A TW337521B TW 337521 B TW337521 B TW 337521B TW 085110724 A TW085110724 A TW 085110724A TW 85110724 A TW85110724 A TW 85110724A TW 337521 B TW337521 B TW 337521B
Authority
TW
Taiwan
Prior art keywords
cloixin
ulcerogenic
analgesic
inflammatory
derivative
Prior art date
Application number
TW085110724A
Other languages
Chinese (zh)
Inventor
Enrlque Aldoma Gustavo
Elida Piatti Susana
Original Assignee
Handforth Invest Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Handforth Invest Ltd filed Critical Handforth Invest Ltd
Application granted granted Critical
Publication of TW337521B publication Critical patent/TW337521B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/80—Acids; Esters in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

A compound of formula (I) 4-nitroxybutyl clonixate and medically acceptable solvent and the salt addition.
TW085110724A 1996-08-16 1996-09-03 Non-ulcerogenic analgesic/anti-inflammatory cloixin derivative TW337521B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/EP1996/003610 WO1998007701A1 (en) 1996-08-16 1996-08-16 Non-ulcerogenic analgesic/anti-inflammatory clonixin derivative

Publications (1)

Publication Number Publication Date
TW337521B true TW337521B (en) 1998-08-01

Family

ID=8166287

Family Applications (1)

Application Number Title Priority Date Filing Date
TW085110724A TW337521B (en) 1996-08-16 1996-09-03 Non-ulcerogenic analgesic/anti-inflammatory cloixin derivative

Country Status (9)

Country Link
JP (1) JP2000516235A (en)
AU (1) AU714258B2 (en)
BR (1) BR9612730A (en)
CA (1) CA2262788A1 (en)
CO (1) CO4900065A1 (en)
PE (1) PE99398A1 (en)
TW (1) TW337521B (en)
UY (1) UY24666A1 (en)
WO (1) WO1998007701A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20030042935A (en) * 2001-11-26 2003-06-02 알앤피코리아 주식회사 Clonixin lysinate formulation
ITMI20021861A1 (en) 2002-08-29 2004-02-29 Nicox Sa NITROXIALKYL ESTER SYNTHESIS PROCESS OF CARBOXYLIC ACIDS, INTERMEDIATES THAT CAN BE USED IN THAT PROCEDURE AND THEIR PREPARATION.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4273777A (en) * 1979-06-04 1981-06-16 Laboratorios Bago S.A. Methods of treating mammals suffering from inflammation and pain
IT1256345B (en) * 1992-08-20 1995-12-01 NITRIC ESTERS OF PHENYLACETIC 2- (2,6-DI-HALO-PHENYLAMIN) DERIVATIVES AND PROCEDURE FOR THEIR PREPARATION

Also Published As

Publication number Publication date
WO1998007701A1 (en) 1998-02-26
UY24666A1 (en) 1998-02-03
AU714258B2 (en) 1999-12-23
JP2000516235A (en) 2000-12-05
PE99398A1 (en) 1999-01-25
CO4900065A1 (en) 2000-03-27
BR9612730A (en) 1999-08-24
CA2262788A1 (en) 1998-02-26
AU6924996A (en) 1998-03-06

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