UY24666A1 - NON-ULCEROGENIC ANALGESIC / ANTI-INFLAMMATORY DERIVATIVE OF CLONIXIN - Google Patents
NON-ULCEROGENIC ANALGESIC / ANTI-INFLAMMATORY DERIVATIVE OF CLONIXINInfo
- Publication number
- UY24666A1 UY24666A1 UY24666A UY24666A UY24666A1 UY 24666 A1 UY24666 A1 UY 24666A1 UY 24666 A UY24666 A UY 24666A UY 24666 A UY24666 A UY 24666A UY 24666 A1 UY24666 A1 UY 24666A1
- Authority
- UY
- Uruguay
- Prior art keywords
- analgesic
- clonixin
- ulcerogenic
- inflammatory
- derivative
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/79—Acids; Esters
- C07D213/80—Acids; Esters in position 3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pain & Pain Management (AREA)
- Pharmacology & Pharmacy (AREA)
- Rheumatology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Un derivado de clonixina o cloxinato de 4-nitroxibutilo, es un nuevo producto analgésico-antiinflamatorio no esteroideo, que tiene un equilibrio extraordinariamente bueno entre una alta actividad analgesica/antiinflamatoria y bajos efectos adversos ulcerogénicos, principalmente como una consecuencia de una sorprendentemente alta actividad antiinflamatoria.A derivative of clonixin or 4-nitroxybutyl cloxinate, it is a new non-steroidal analgesic-anti-inflammatory product, which has an extraordinarily good balance between high analgesic / anti-inflammatory activity and low ulcerogenic adverse effects, mainly as a consequence of surprisingly high anti-inflammatory activity. .
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
PCT/EP1996/003610 WO1998007701A1 (en) | 1996-08-16 | 1996-08-16 | Non-ulcerogenic analgesic/anti-inflammatory clonixin derivative |
Publications (1)
Publication Number | Publication Date |
---|---|
UY24666A1 true UY24666A1 (en) | 1998-02-03 |
Family
ID=8166287
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
UY24666A UY24666A1 (en) | 1996-08-16 | 1997-08-12 | NON-ULCEROGENIC ANALGESIC / ANTI-INFLAMMATORY DERIVATIVE OF CLONIXIN |
Country Status (9)
Country | Link |
---|---|
JP (1) | JP2000516235A (en) |
AU (1) | AU714258B2 (en) |
BR (1) | BR9612730A (en) |
CA (1) | CA2262788A1 (en) |
CO (1) | CO4900065A1 (en) |
PE (1) | PE99398A1 (en) |
TW (1) | TW337521B (en) |
UY (1) | UY24666A1 (en) |
WO (1) | WO1998007701A1 (en) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
KR20030042935A (en) * | 2001-11-26 | 2003-06-02 | 알앤피코리아 주식회사 | Clonixin lysinate formulation |
ITMI20021861A1 (en) * | 2002-08-29 | 2004-02-29 | Nicox Sa | NITROXIALKYL ESTER SYNTHESIS PROCESS OF CARBOXYLIC ACIDS, INTERMEDIATES THAT CAN BE USED IN THAT PROCEDURE AND THEIR PREPARATION. |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4273777A (en) * | 1979-06-04 | 1981-06-16 | Laboratorios Bago S.A. | Methods of treating mammals suffering from inflammation and pain |
IT1256345B (en) * | 1992-08-20 | 1995-12-01 | NITRIC ESTERS OF PHENYLACETIC 2- (2,6-DI-HALO-PHENYLAMIN) DERIVATIVES AND PROCEDURE FOR THEIR PREPARATION |
-
1996
- 1996-08-16 WO PCT/EP1996/003610 patent/WO1998007701A1/en not_active Application Discontinuation
- 1996-08-16 JP JP10510291A patent/JP2000516235A/en active Pending
- 1996-08-16 AU AU69249/96A patent/AU714258B2/en not_active Ceased
- 1996-08-16 BR BR9612730A patent/BR9612730A/en not_active Application Discontinuation
- 1996-08-16 CA CA002262788A patent/CA2262788A1/en not_active Abandoned
- 1996-09-03 TW TW085110724A patent/TW337521B/en active
-
1997
- 1997-08-12 UY UY24666A patent/UY24666A1/en unknown
- 1997-08-14 PE PE1997000716A patent/PE99398A1/en not_active Application Discontinuation
- 1997-08-15 CO CO97046964A patent/CO4900065A1/en unknown
Also Published As
Publication number | Publication date |
---|---|
CA2262788A1 (en) | 1998-02-26 |
PE99398A1 (en) | 1999-01-25 |
AU6924996A (en) | 1998-03-06 |
AU714258B2 (en) | 1999-12-23 |
BR9612730A (en) | 1999-08-24 |
TW337521B (en) | 1998-08-01 |
CO4900065A1 (en) | 2000-03-27 |
WO1998007701A1 (en) | 1998-02-26 |
JP2000516235A (en) | 2000-12-05 |
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