US9289698B2 - Method for producing extracts from materials and device for realizing same - Google Patents

Method for producing extracts from materials and device for realizing same Download PDF

Info

Publication number
US9289698B2
US9289698B2 US13/574,974 US201013574974A US9289698B2 US 9289698 B2 US9289698 B2 US 9289698B2 US 201013574974 A US201013574974 A US 201013574974A US 9289698 B2 US9289698 B2 US 9289698B2
Authority
US
United States
Prior art keywords
vacuum
extraction
extractant
mixture
raw materials
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related, expires
Application number
US13/574,974
Other languages
English (en)
Other versions
US20120301550A1 (en
Inventor
Yakov Kuzmich Abramov
Vladimir Mihailovich Veselov
Viktor Mihailovich Zalevsky
Vitaly Grigorevich Tamurka
Olga Borisovna Smirnova
Natalja Vladimirovna Veselova
Veniamin Sergeevich Volodin
Larisa Sergeevna Ermakova
Anatoly Fedorovich Khanin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Twin Technology Co
Original Assignee
Twin Technology Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Twin Technology Co filed Critical Twin Technology Co
Publication of US20120301550A1 publication Critical patent/US20120301550A1/en
Application granted granted Critical
Publication of US9289698B2 publication Critical patent/US9289698B2/en
Expired - Fee Related legal-status Critical Current
Adjusted expiration legal-status Critical

Links

Images

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D11/00—Solvent extraction
    • B01D11/02—Solvent extraction of solids
    • B01D11/0215—Solid material in other stationary receptacles
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D11/00—Solvent extraction
    • B01D11/02—Solvent extraction of solids
    • B01D11/0215—Solid material in other stationary receptacles
    • B01D11/0219—Fixed bed of solid material
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D11/00—Solvent extraction
    • B01D11/02—Solvent extraction of solids
    • B01D11/0215—Solid material in other stationary receptacles
    • B01D11/0223—Moving bed of solid material
    • B01D11/0226—Moving bed of solid material with the general transport direction of the solids parallel to the rotation axis of the conveyor, e.g. worm
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D11/00—Solvent extraction
    • B01D11/02—Solvent extraction of solids
    • B01D11/0261—Solvent extraction of solids comprising vibrating mechanisms, e.g. mechanical, acoustical
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
    • C11B9/00—Essential oils; Perfumes
    • C11B9/02—Recovery or refining of essential oils from raw materials
    • C11B9/025—Recovery by solvent extraction
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01D—SEPARATION
    • B01D11/00—Solvent extraction
    • B01D2011/007—Extraction using a solvent in the gas phase

Definitions

  • the invention relates to a process of extraction with the use of vacuum and can be used to extract the drug or other valuable bioactive agents from plant, animal, fish, seafood and other types of raw materials used in chemical, food and cosmetic industry and medicine.
  • a method of producing extracts is currently in use (patent RU 2232026 A61K35/78, V01D 11/02) by means of extraction of ground plant raw material under vacuum (up to ⁇ 0.3 atm.) at 15-35° C. for 1-15 days, using structured water as the extractant.
  • the main disadvantage of this method is that the process of extraction is carried out in a laminar diffusion regime (infusion at a fixed bed of solid phase), in which a rapid saturation of an extractant layer near the solid particles with extractables takes place, which leads to a decrease in the concentration gradient during the saturation time and the fall effectiveness of the extraction process.
  • the said method does not provide a sufficient overheating of the solvent in the material, which leads to a decrease in the yield of extractable substances.
  • the disadvantage of this method is a significant process duration (1-15 days), which does not exclude the formation of various microorganisms, especially bacteria, molds, fungi, yeast and can lead to a souring of a mixture.
  • a method of extracting materials is currently in use (patent RU 2163827 V01D 11/02), including the crushing of raw materials, vacuum treatment, contacting with a solvent, heating of a mixture and extracting in a vacuum-impulsive mode. Prior contacting with components the solvent and raw materials are heated and degassed using a vacuum-impulsive treatment. The heating of the components and their mixtures is carried out to a temperature not causing the denaturation of the material. The extraction is carried out at a residual pressure of 0.1-13.3 kPa and at time to achieve it and relief—0.5-1.0 sec, temperature of 40-80° C. at the module (extractant:raw materials) which is equal to 10.
  • Said method of extraction has some disadvantages. Under the proposed modes of vacuum treatment the method does not provide a sufficiently complete extraction of components from the raw materials. Extraction of raw materials is carried out at high flow rate of extractant (module (extractant:raw materials) is equal to 10). Moreover, the extraction process is carried out at temperatures of 40-80° C., in consequence of which a destruction of a number of biologically active components takes place, which greatly reduces the quality of the extracts obtained.
  • the method includes the grinding and heating of raw materials, the degassing of raw materials and extractant, heating the solvent to a temperature by 5-15° C. below the temperature of heating of raw materials, at that the degassing of raw materials and extractant is carried out separately using impulsive-vacuum treatment including keeping the mixture during 3-5 minutes after each impulsive-vacuum treatment cycle.
  • the extraction is carried out in vacuum-impulsive mode at 70° C. and residual pressure in the receiver of 1-10 mm. Hg.
  • An apparatus that realizes the said method of extraction is currently in use (patent RU 2213606 V01D 11/02) containing an extractant tank and extractor, which are interconnected and to a pipeline through the quick response valves, to a condensate receiving tank and receiver, a vacuum pump which is connected to a receiver, a reflux condenser which is installed above the extractor, providing a condensation of the vapor of the extractant, a heater and a pump providing heating and delivering of the heating liquid medium into the extractant tank and the extractor tank.
  • the said method of extraction and the apparatus possess some disadvantages. Under the proposed mode of vacuum treatment the method and apparatus do not provide a sufficiently complete extraction of components from the raw materials. Extraction of raw materials is carried out at high flow rate of extractant (module extractant:raw material is equal to 10). Moreover, the extraction processes are carried out at temperatures up to 70° C., in consequence of which a destruction of various biologically active components takes place, which greatly reduces the quality of the extracts obtained. The latter circumstance leads to the inapplicability of the method for obtaining high-quality pharmaceutical preparations of plant, animal raw materials and seafoods.
  • An apparatus for producing the extracts (inventor's certificate SU No V01D 850 108 11/00) which has a cylindrical body with a rotor, separated with the radial walls into chambers, equipped with hinged bottom doors and spray system with shut-off valves in the upper part of the solvent receiver, the device for loading and unloading of solid substances.
  • the extractor is equipped with bars, which are installed including the ability of reciprocal motion, located on them turners, guide and lever connected to the Shut-off valve.
  • the disadvantage of this apparatus includes raised packing of solid mass on the surface of the bottom, while the reciprocating motion of agitator turners occurring, which increases the hydraulic resistance of the layer of a solid phase, reducing the velocity and quality of the extraction process.
  • the disadvantage is also includes a structural complexity of the apparatus.
  • the aim of the present invention is to develop a method for extracting of different types of biological raw materials and the apparatus for implementing this method, allowing to increase the yield of extractable substances and improve their quality due to the possibility of conducting the processes at lower temperatures, as well as preventing oxidative reactions in the material.
  • a method comprising heating the extractant, the preliminary extraction of raw materials on the heated rollers with the extractant at the module (extractant:raw materials), not more than 2, the impregnation of the raw materials with extractant and extraction of the raw material in the vacuum-impulsive mode allows performing, the impregnation and extraction of raw materials in the vacuum-pulse mode in a cycle mode, which includes the heating with hot coolant gas and creating a vacuum in the chamber in a high-velocity mode from the atmospheric pressure to a pressure not exceeding 0.01 MPa, and then from the previous pressure to a pressure not more than 0.0001 MPa, followed by the exposure under vacuum to stabilize the temperature of the mixture and vacuum relief at the end of the cycle by means of delivering of hot coolant gas, at that the heating of raw materials is carried out to a temperature not exceeding 39° C.
  • the method involves the use of distilled water or organic solvents or their mixtures as an extractant.
  • coolant gas a chemically inert gas that prevents oxidation reactions in the materials is used as coolant gas.
  • an apparatus which includes a screw doser connected to the extractant tank, the continuous heated rollers, equipped with a mesh receiving container to collect the resulting presscake, impregnated with extractant, one or two extractors, connected with a pipeline through valves with reflux condenser, extract receiving tank in their turn are interconnected to a receiver, which is connected to the vacuum pump, additionally equipped with a bubblers installed at the bottom of each extractor and connected to a coolant gas supply system through the pipeline, and to additional one or more receivers with vacuum pumps, installed parallel to the first receiver and connected through a system of vacuum pipes with quick response valves to inputs to the extractors.
  • Bubblers may have the holes of diameter of 1-6 mm for a better process intensification.
  • Coolant gas supply system is equipped with a fan and heating device.
  • the apparatus is equipped with a source of inert gas to carry out the process of extraction of materials containing readily oxidizable substances.
  • the proposed method and apparatus allow conducting the efficient extraction of raw materials at low temperatures (not exceeding 39° C.), which is explained as follows.
  • Vacuum-impulsive extraction of raw material with a stepwise pressure drop accelerates the diffusion of the extractant into the deeper structures of a material and inside the cells with each step, which is accompanied by intense heat- and mass transfer and, consequently, leads to a more complete extraction of components from raw materials.
  • at sharp impulsive pressure drop up to saturated vapor pressure the formation of cavitation bubbles of extractant takes place, resulting in a hydraulic shock in the mix, and as a result in disintegration and homogenization of the material.
  • Number of pressure drops steps and vacuum impulses depend on the type of starting materials and the need for extraction of some components.
  • Vacuum relief and heating the mixture is performed by means of delivering to the extracting chamber of heated gas coolant through bubblers with holes of 1-6 mm in diameter, which creates a “boiling centers” in the system, provides the mixing and homogenization of the mixture, increases the mass- and heat transfer, favors a more efficient extraction.
  • the process is accompanied by strong shock waves in the extraction mixture, which further breaks down the cellular structure of the material due to shock loadings and the accumulation of dynamic and fatigue stresses resulting from changes in the difference of the intracellular and external pressure. Consequently, a stepwise multiple vacuum-impulse extraction of raw materials accompanied by the increase the vacuum depth at each step and the delivering of heated coolant gas into the extraction chamber have synergism.
  • Use of receivers, connected in parallel to the extractors in an apparatus provides an opportunity to conduct more intensive process of extracting in a vacuum-impulsive mode by means of stepwise vacuum creation, at first from the first receiver, then from the second receiver with deeper vacuum.
  • the drawing shows the apparatus for the extraction of materials, which includes a screw doser 1 , which is delivered with raw materials into its hopper and extractant is dosed in from the extractant tank 2 .
  • a screw doser 1 which is delivered with raw materials into its hopper and extractant is dosed in from the extractant tank 2 .
  • the continuous heated rollers 3 are installed for pre-extraction process conducting.
  • a presscake obtained on rollers 3 , impregnated with extractant, is collected in the receiving mesh container 4 of the tank 5 .
  • the apparatus is equipped with the extractors 6 (which a container with the starting pulp is installed in).
  • the reflux condenser 7 is installed, which is connected to them through the valves 8 of common pipeline 9 .
  • the extractors 6 are equipped with the bubblers 10 , installed in the bottom of each extractor 6 and are connected by pipeline 11 to a coolant gas supply system 12 through the valve 13 .
  • the resulting extract is collected in the extract receiving tank 14 .
  • the pipelines connect all parts of apparatus to each other and to the receivers 15 and 16 , which are delivered with vacuum with the vacuum pumps 17 , 18 and 19 through quick-response valves 20 , 21 and 22 , and the connection with the atmosphere is performed through the valves 23 and 24 .
  • Each part of apparatus is equipped with valves, respectively, to connect to vacuum line 25 .
  • connection of receivers 15 , 16 , and the vacuum pumps 17 , 18 and 19 allow applying a multiple stepwise pressure drop and creating more favorable conditions for the extraction of materials in the vacuum-impulsive mode.
  • the device of coolant gas delivering 12 is equipped with the fan 26 and heating device 27 .
  • the device for extraction is equipped with the inert gas source 28 , used while extracting of easily oxidized substances.
  • the device for extraction operates as follows:
  • the raw materials are washed and cleared.
  • the extractant In the extractant tank 2 , the extractant is heated to the process operating temperature.
  • the distilled water, or organic solvents, or mixtures thereof are used as the extractants.
  • the prepared raw material with screw doser is delivered to a continuous heated rollers 3 , simultaneously heated extractant is delivered from the extractant tank 2 into a screw doser hopper in the amount required to ensure the module extraction (extractant:raw materials), should not be more than 2.
  • extractant is delivered from the extractant tank 2 into a screw doser hopper in the amount required to ensure the module extraction (extractant:raw materials), should not be more than 2.
  • the mixture of raw material and extractant is heated (to a temperature not exceeding 39° C.), under the influence of shearing deformations the material is crushed, intensely mixed and pre-extracted. Due to extractant absorption by ground raw material at shearing deformations, the extraction process proceeds up to the start of pressing of raw materials with rollers.
  • the partial destruction of fibrillar structure of material and part of membranous walls occurs.
  • the diffusion of extractant into the material structure increases and intensifies leading to yield increase of extractable components.
  • the receiving mesh container 4 with the obtained on continuous heated rollers 3 heated started presscake, mixed with the extractant, is installed in one of extractors 6 , which is connected to the receivers through a vacuum line with quick response valve 22 .
  • the two extractors 6 are provided to ensure the process continuity. While mixture heating is carried out in one extractor, the vacuum treatment is carried out in another on and vice versa. Then the heated extractant is delivered into the extractor, so that the total module (extractant:raw materials) amounted to no more than 4.
  • the mixture is heated with hot coolant gas to operating temperature not exceeding 39° C. After this the quick pressure drop (quick vacuum treatment) is performed for no more than 1.0 sec.
  • the extractor 6 While vacuum treatment is performed, the extract ant is partially vaporized; resulting in reduced temperature of the mixture, the boiling stops, and the temperature stabilizes.
  • the extractor 6 Upon exposure under vacuum (1-3 min.), the extractor 6 is connected to the coolant gas supply system 12 , at that vacuum is relieved, and coolant gas, while passing through the bubblers 10 with holes of small diameter (1-6 mm.), provides a mixing and homogenization of the mixture.
  • the residual gases and vapors are removed from the surface and inner layers of raw materials, the surface area is increased that enables the efficiency of the following vacuum-impulsive extraction.
  • Vacuum-impulsive extraction is carried out at operating temperature not exceeding 39° C.
  • the mixture is heated to the required temperature with heated coolant gas delivered through a bubbler 10 into the extractor 6 , a quick pressure drop (quick vacuum treatment) is performed for no more than 1.0 sec: from atmospheric pressure to a pressure not exceeding 0.01 MPa by means of extractor 6 connecting to the receiver 15 and then quick pressure drop for less than 1.0 sec. from the previous pressure to a pressure of not more than 0.0001 MPa by means of chamber connection to the receiver 16 .
  • the mixture is kept under vacuum until stop of the solvent boiling and stabilizing the temperature of the material (1-3 min), depending upon the type of the extracted material.
  • an inert gas supplied from the inert gas source 28 is used as the coolant gas.
  • the obtained extract is collected to the extract receiving tank 14 .
  • 0.5 kg of sea buckthorn seeds is placed in a screw doser hopper.
  • a mass of sea buckthorn seeds is covered with extractant (vegetable oil) heated to a temperature of 39° C. (module 1).
  • extractant vegetable oil
  • the mixture is delivered with the screw doser to the heated rollers, which support the temperature of 38-39° C., and rolled for 4 min.
  • the resulting presscake from rollers is placed into the extractor, additional hot extractant is added (module 3), heated with hot purified air to 39° C. and subjected to a quick vacuum-impulsive exposure for 0.5 sec.
  • the maximum extraction of all the carriers of healing properties of sea buckthorn seeds takes place, in addition, in the medium of oil the biological activity of the seeds is kept for a long time, and their preservation takes place in the concentration which is achieved in the raw material (the degree of maturity), and the resulting oil extracts have high anti-inflammatory, antibacterial and antioxidant properties.
  • 0.5 kg of marigold flowers is placed into a screw doser hopper.
  • a mass of marigold flowers is covered with extractant (dimexide), which is heated to a temperature of 39° C. (module 2).
  • extractant diimexide
  • the mixture is delivered with the screw doser to the heated rollers which support the temperature of 38-39° C., and rolled for 3 min.
  • the extractors, extractant tank and the extract receiving tank are blown off with the nitrogen.
  • the resulting presscake from rollers is placed into the extractor, additional hot extractant is added (module 4), heated with hot purified air to 39° C. and subjected to a quick vacuum-impulsive exposure for 0.5 sec.
  • dimexidum dramatically accelerates the absorption through skin and mucous membranes of many drugs, creating the perfect base for drugs.
  • a solvation of molecules of biologically active compounds takes place, which positively affects the stability of the obtained extracts.
  • washed fish residues (bones, cartilages, heads, skin, bladders, scale, fins and liver of the sturgeon fish) are placed into a screw doser hopper.
  • Fish residues are covered with extractant (50% aqueous ethanol), heated to a temperature of 30-32.degree. C., (module 1).
  • extractant 50% aqueous ethanol
  • the mixture is delivered with the screw doser to the heated rollers, which support the temperature of 30-32.degree C., and rolled for 5 minutes.
  • Resulting carefully crushed mass from rollers is placed into the extractor, additional hot extract ant is added (module 3), heated with hot purified air to a temperature of 30-32.degree. C. and subjected to quick vacuum-impulsive exposure for 0.5 sec.
  • skimmed milk 1 kg. is placed into a screw doser hopper.
  • the milk powder is wetted with the extractant (65% aqueous ethanol) (Module 0.5) and delivered with the screw doser to the rollers that support the temperature of the mixture below 25° C., and rolled for 1 min.
  • Wetting of skimmed milk on the rollers with 65% ethanol causes a transition of lactose from amorphous to the crystalline state, greatly improving the wetting of milk.
  • Lactose-free milk product obtained according to this method, has a high quality and can be used to feed children and adults who, because of partial or complete indigestibility of lactose, cannot be fed with the unskimmed milk.

Landscapes

  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Physics & Mathematics (AREA)
  • Acoustics & Sound (AREA)
  • Mechanical Engineering (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Wood Science & Technology (AREA)
  • Organic Chemistry (AREA)
  • Extraction Or Liquid Replacement (AREA)
  • Treatment Of Fiber Materials (AREA)
  • Ropes Or Cables (AREA)
US13/574,974 2010-02-03 2010-08-13 Method for producing extracts from materials and device for realizing same Expired - Fee Related US9289698B2 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
RU2010103414 2010-02-03
RU2010103414/05A RU2402368C1 (ru) 2010-02-03 2010-02-03 Способ экстрагирования материалов и устройство для его осуществления
PCT/RU2010/000447 WO2011096843A1 (ru) 2010-02-03 2010-08-13 Способ экстрагирования материалов и устройство для его осуществления

Publications (2)

Publication Number Publication Date
US20120301550A1 US20120301550A1 (en) 2012-11-29
US9289698B2 true US9289698B2 (en) 2016-03-22

Family

ID=44042182

Family Applications (1)

Application Number Title Priority Date Filing Date
US13/574,974 Expired - Fee Related US9289698B2 (en) 2010-02-03 2010-08-13 Method for producing extracts from materials and device for realizing same

Country Status (7)

Country Link
US (1) US9289698B2 (ja)
EP (1) EP2532402A4 (ja)
JP (1) JP5699358B2 (ja)
KR (1) KR101749785B1 (ja)
CN (1) CN102740942B (ja)
RU (1) RU2402368C1 (ja)
WO (1) WO2011096843A1 (ja)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103772473B (zh) * 2014-01-10 2015-07-29 吉首大学 一种真空脉动式提取纯化迷迭香中熊果酸的方法
CN104971514B (zh) * 2014-08-10 2016-12-07 嵊州市宜留机械科技有限公司 用于提取映山红总黄酮的设备
DE102014013856A1 (de) * 2014-09-24 2016-03-24 Jörg Beckmann Verfahren zum Reinigen und/oder Trennen von Feststoffen
CN104759110B (zh) * 2015-03-12 2016-03-30 浙江天草生物科技股份有限公司 一种植物连续提取系统
SE538862C2 (sv) * 2015-05-21 2017-01-10 Scania Cv Ab Metod och kommersiellt fordon innefattande omdirigeringsmedel för luftflöde
EP3244984A4 (en) * 2015-06-25 2018-07-04 Kotelkin, Igor Mikhaylovich Method and production line for the production of protein product from protein raw material
CN104957687B (zh) * 2015-07-02 2017-08-18 深圳市润唐发明电器有限公司 应用于药用或食用材料的提取设备
KR20180083251A (ko) * 2015-12-11 2018-07-20 오브쉐스트보 에스 오그라니쉐노이 오?스트베노스트유 ˝트윈 테크놀로지 컴퍼니˝ 셀룰로스의 제조 방법
CN107137261B (zh) * 2017-03-24 2018-07-10 上海伽誉生物科技有限公司 龙胆抗刺激因子的制备方法、用途及植物提取装置
CN109289245A (zh) * 2018-11-08 2019-02-01 飞潮（无锡）过滤技术有限公司 一种700Mpa连续式超高压萃取分离装置
CN112426743B (zh) * 2020-11-02 2022-08-09 恩施农禅谷生态农业发展有限公司 一种用于化妆品生产的原料提取装置
CN116240070A (zh) * 2022-05-04 2023-06-09 新纪元食品科技(佛山)有限公司 一种浸出油脂的工艺

Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB252190A (en) 1925-05-14 1927-07-07 Eugene Foray Apparatus for the extraction of the essential principles of substances, and their combination with a suitable base
GB912326A (en) 1959-12-28 1962-12-05 Gunnar Koelle Improvements in or relating to extracting a constituent extractable by a liquid in the cold from a material containing same
SU850108A1 (ru) 1979-10-17 1981-07-30 Всесоюзный Научно-Исследовательскийинститут Биосинтеза Белковыхвеществ Экстрактор дл системы твердоеТЕлО-жидКОСТь
RU2063784C1 (ru) 1992-01-04 1996-07-20 Василенко Николай Васильевич Экстрактор для системы твердое тело - жидкость
RU2163827C2 (ru) 1998-07-06 2001-03-10 Абрамов Яков Кузьмич Способ экстрагирования материалов
RU2213606C1 (ru) 2002-01-21 2003-10-10 Голицын Владимир Петрович Способ экстрагирования материалов
RU2332026C1 (ru) 2007-01-25 2008-08-27 Олег Иванович Квасенков Способ производства консервов "язык с соусом из зеленого горошка" специального назначения (варианты)
RU2344166C2 (ru) 2006-09-20 2009-01-20 Виталий Аркадьевич Хуторянский Способ комплексной переработки растительного сырья

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61141901A (ja) * 1984-12-17 1986-06-28 Mitsuo Sohgoh Kenkyusho Kk 物質の変圧処理法
JPH01159004A (ja) * 1987-12-16 1989-06-22 Niigata Eng Co Ltd 固体抽出法
US6111119A (en) * 1999-01-14 2000-08-29 Cocotech, Inc. Process for removing oil from food products
RU2232026C2 (ru) 2002-04-19 2004-07-10 Соколов Виктор Владимирович Способ получения экстракта из растительного сырья
JP2005193114A (ja) * 2004-01-05 2005-07-21 Shinryo Corp 植物中の重金属の抽出方法
JP4719695B2 (ja) * 2006-01-26 2011-07-06 株式会社フロンティアエンジニアリング 抽出装置および抽出方法
JP4803437B2 (ja) 2006-04-26 2011-10-26 廣瀬 文則 タンニン抽出液、タンニン粉末、それらの重金属との錯体、及びそれらの製造方法
JP2008043840A (ja) 2006-08-11 2008-02-28 Tetsuro Asao 有効成分の抽出方法
GB0700924D0 (en) 2007-01-18 2007-02-28 Murdoch Thomas Edge protector
CN101358158A (zh) * 2008-09-19 2009-02-04 石河子大学 一种新鲜芳香植物精油的制备方法
RU2382669C1 (ru) * 2008-12-29 2010-02-27 ЗАО "Твин Трейдинг Компани" Способ экстрагирования материалов и устройство для его осуществления

Patent Citations (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB252190A (en) 1925-05-14 1927-07-07 Eugene Foray Apparatus for the extraction of the essential principles of substances, and their combination with a suitable base
GB912326A (en) 1959-12-28 1962-12-05 Gunnar Koelle Improvements in or relating to extracting a constituent extractable by a liquid in the cold from a material containing same
SU850108A1 (ru) 1979-10-17 1981-07-30 Всесоюзный Научно-Исследовательскийинститут Биосинтеза Белковыхвеществ Экстрактор дл системы твердоеТЕлО-жидКОСТь
RU2063784C1 (ru) 1992-01-04 1996-07-20 Василенко Николай Васильевич Экстрактор для системы твердое тело - жидкость
RU2163827C2 (ru) 1998-07-06 2001-03-10 Абрамов Яков Кузьмич Способ экстрагирования материалов
RU2213606C1 (ru) 2002-01-21 2003-10-10 Голицын Владимир Петрович Способ экстрагирования материалов
RU2344166C2 (ru) 2006-09-20 2009-01-20 Виталий Аркадьевич Хуторянский Способ комплексной переработки растительного сырья
RU2332026C1 (ru) 2007-01-25 2008-08-27 Олег Иванович Квасенков Способ производства консервов "язык с соусом из зеленого горошка" специального назначения (варианты)

Also Published As

Publication number Publication date
KR20120125333A (ko) 2012-11-14
WO2011096843A8 (ru) 2015-01-15
WO2011096843A1 (ru) 2011-08-11
CN102740942A (zh) 2012-10-17
EP2532402A4 (en) 2017-08-09
JP2013518714A (ja) 2013-05-23
JP5699358B2 (ja) 2015-04-08
RU2402368C1 (ru) 2010-10-27
KR101749785B1 (ko) 2017-06-21
EP2532402A1 (en) 2012-12-12
CN102740942B (zh) 2014-11-26
US20120301550A1 (en) 2012-11-29

Similar Documents

Publication Publication Date Title
US9289698B2 (en) Method for producing extracts from materials and device for realizing same
JP2013518714A5 (ja)
US10011804B2 (en) Method of extracting CBD, THC, and other compounds from cannabis using controlled cavitation
EP2716340A1 (en) Method in which moisture content of processing object is reduced and/or oil-soluble substance in processing object is extracted in oil
US11912957B2 (en) Method and an apparatus for preparing a high-polyphenols olive oil
US11807828B2 (en) Agitator for solventless extraction of cannabis essential oils
CN106701851A (zh) 一种大蒜素的提取方法
Both et al. Mass transfer enhancement for solid–liquid extractions
US20220346413A1 (en) System and method for continuous microwave-assisted extraction of bioactive agents from biomass
JP2018007654A (ja) 生物由来液獲得方法
RU2372132C1 (ru) Способ получения водосодержащих пропиленгликолевых экстрактов растительного сырья с повышенной устойчивостью к микробиологическому загрязнению
KR101170471B1 (ko) 천연식물로부터 유효성분을 추출/농축하여 엽록소를 얻는 제조방법
KR101158566B1 (ko) 염록소와 베타글루칸의 혼합음료 및 그 제조방법
CN108840926A (zh) 液体畜禽血红蛋白的高效制备方法
RU2505076C2 (ru) Способ получения экстракта ягод годжи
KR100629927B1 (ko) 엽록소 음료의 제조 방법
CN105038972A (zh) 瓜蒌籽油超临界萃取工艺
RU2403808C1 (ru) Способ получения экстрактов
RU2799883C1 (ru) Способ получения сухого растительного экстракта
CN113045377B (zh) 一种基于亚临界萃取与超临界制粒组合工艺的番茄红素微粒的制备方法
Singh Maceration, Percolation and Infusion Techniques of Extraction of Medicinal and Aromatic Plants (MAPs)
CN210856046U (zh) 一种精油提炼设备
JP2010235832A (ja) 柑橘類果皮からの油分の除去方法、柑橘類果皮の粉末化方法、及びその粉末からなる入浴剤、機能性食品、並びに柑橘類果皮の粉末複合化製品の製造方法
Liu et al. Removal of lipid and cholesterol from goat placenta by supercritical carbon dioxide extraction
Olivira et al. Basic Principle of Plants Bioactive Compounds Extraction Using Various Extraction Methods

Legal Events

Date Code Title Description
STCF Information on status: patent grant

Free format text: PATENTED CASE

FEPP Fee payment procedure

Free format text: MAINTENANCE FEE REMINDER MAILED (ORIGINAL EVENT CODE: REM.); ENTITY STATUS OF PATENT OWNER: SMALL ENTITY

LAPS Lapse for failure to pay maintenance fees

Free format text: PATENT EXPIRED FOR FAILURE TO PAY MAINTENANCE FEES (ORIGINAL EVENT CODE: EXP.); ENTITY STATUS OF PATENT OWNER: SMALL ENTITY

STCH Information on status: patent discontinuation

Free format text: PATENT EXPIRED DUE TO NONPAYMENT OF MAINTENANCE FEES UNDER 37 CFR 1.362

FP Lapsed due to failure to pay maintenance fee

Effective date: 20200322