US3918451A - Inhalator for pulverulent substances - Google Patents

Inhalator for pulverulent substances Download PDF

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Publication number
US3918451A
US3918451A US506611A US50661174A US3918451A US 3918451 A US3918451 A US 3918451A US 506611 A US506611 A US 506611A US 50661174 A US50661174 A US 50661174A US 3918451 A US3918451 A US 3918451A
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US
United States
Prior art keywords
inhalator
case
cover portion
reception space
capsule
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
US506611A
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English (en)
Inventor
Emeram Steil
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
STARNBERG A CORP OF GERMANY
RITZAU PARI WERK KG PAUL
Original Assignee
RITZAU PARI WERK KG PAUL
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by RITZAU PARI WERK KG PAUL filed Critical RITZAU PARI WERK KG PAUL
Application granted granted Critical
Publication of US3918451A publication Critical patent/US3918451A/en
Assigned to STARNBERG A CORP. OF GERMANY reassignment STARNBERG A CORP. OF GERMANY ASSIGNMENT OF ASSIGNORS INTEREST. Assignors: PAUL RITZAU PARI-WERK KG A GERMAN CORP
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0033—Details of the piercing or cutting means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M15/00—Inhalators
    • A61M15/0028—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up
    • A61M15/003—Inhalators using prepacked dosages, one for each application, e.g. capsules to be perforated or broken-up using capsules, e.g. to be perforated or broken-up
    • A61M15/0033—Details of the piercing or cutting means
    • A61M15/004—Details of the piercing or cutting means with fixed piercing or cutting means
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2202/00—Special media to be introduced, removed or treated
    • A61M2202/06—Solids
    • A61M2202/064—Powder

Definitions

  • the cover In one position the cover exposes the reception space to permit insertion and removal of capsules at which position the cover is interlocked with the case.
  • the cover Upon insertion of a capsule the cover is automatically unlocked from the case and moves under the spring bias to a position to cover the capsule and to a further position at which cutting members coupled to the cover move into the reception space to open the capsule.
  • the invention relates to an inhalator for pulverulent substances contained in capsules insertible into themhalator case, with an inlet and an outlet forthe respiratory air.
  • An inhalator of this type which is applied in medicine for example, is already known. It offers the advantage that, by the insertion of a capsule, a precisely dosed quantity of the substance which is to be inhaled is present within the apparatus, so that when it is needed, e.g. during acute asthmatic attacks, no harmful excess dosage can be inhaled. It is handy moreover, and may easily be stowed inside a pocket.
  • the inhalator of the kind described in the foregoing is so formed that the capsule is pushed into a rotatably installed cylindrical sleeve which may be placed in wobbling rotary motion when a flow of air is drawn through a suction via the mouthpiece installed on the apparatus, by means of' propeller blades arranged thereon.
  • the pulverulent substance present within the previously pierced capsule is concomitantly raised from the latter by turbulence, whereupon it penetrates the patients mouth via the mouthpiece, together with the air sucked in. It is a disadvantage of this apparatus, that it must be disassembled into three parts when fitting each capsule, and that it must be serviced approximately once a week, i.e. dismantled, cleaned and oiled.
  • the object of the present invention is'to eliminate these disadvantages and to provide an uncomplicated and reliably operated inhalator, which is handy, requires no maintenance and is reliable.
  • this problem is resolved in that the capsule reception space is situated at the periphery of the case with aside open at the periphery and is equipped with a cover movably arranged thereon, and which uncovers the capsule reception space in a filling and emptying position and covers it in another position.
  • This cover may be rotatably arranged, and may comprise an aperture acting as a passage for traversal by the capsule.
  • the cover may be stopped at the filling and emptying position by means of a stop pin guided in longitudinally displaceable manner with respect to a notch of the cover.
  • This stop pin may have connected to it an ejector for capsules present within the reception space, in such manner that it is insertable into the reception space under the force of a spring and at the same time moves the stop pin into the notch of the cover.
  • the ejector and the stop pin are then pushed into the inside of the case, the latter concomitantly cancelling the immobilisation.
  • a spring member may then automatically move the cover into the idle position.
  • the cover may be equipped with a device for opening capsules, for example in the form of two small blades, which under a force acting against the spring as described in the foregoing, may be pushed into the reception space of the capsule.
  • the cover may be formed in a variety of ways, e.g. as a cylindrical sleeve partially surrounding the apparatus, as a slider, or as a removable lid.
  • the cover is preferably produced in transparent form, so that the blades and capsule remain permanently visible, in order to show whether a new unopened capsule has been inserted.
  • an inhalator for pulverulent substances comprising an inhalator case having an inlet and an outlet for passing respiratory air, a reception space formed on the outer periphery of the case for insertably receiving a capsule containing a pulverulent substance, means for mounting a cover portion on the inhalator case for movement with respect thereto between a first position whereat the cover portion encloses the capsule in the reception space and a second position at which the cover portion uncovers the capsule in the reception space to permit removal and replacement thereof.
  • the advantages of the present invention consist in that as a consequence of the incorporation of the capsule reception space at the periphery of the case, in combination with a removable cover, a new capsule may be inserted without dismantling the case.
  • the spring arrangement of the cover has the result that the cover moves automatically to the idle position and thus eliminates confusion between the opening and the idle or operating positions, which exists in the known systems.
  • the ejector arranged under spring loading considerably simplifies the handling of the apparatus.
  • the omission of a turbo impeller wheel simplifies the operation and improves the reliability of the apparatus.
  • FIG. 1 shows an overall view of the apparatus in the operating or idle position
  • FIG. 2 shows a cross-section of the apparatus in the filling and emptying position, along the line IIII in FIG. 1,
  • FIG. 3 shows a cross-section of the apparatus in the operating or idle position, along the line IIIIII in FIG.
  • FIG. 4 shows a cross-section of the apparatus in the pricking-open position, along the line IIIIII in FIG. I.
  • an inhalator comprises a cylindrical case 2 and is equipped with a mouth piece 17 at its one terminal extremity.
  • An aperture 4 of a cover 3 may be brought into the filling and emptying position shown in FIG. 2, against the spring force of a spring member 16.
  • a stop pin 6 which is guided within the case in a perforation 7 and rigidly coupled to an ejector 10 is then pushed into a then available notch 8 of the cover 3 as a consequence of the spring force of another spring member 9, and immobilises the cover.
  • a capsule 11 may be pushed into a reception space 1 of the inhalator against the ejector I0 projecting into the same, in such manner that the stop pin coupled to it is released at the same time, the cover 3 concomitantly being displaced by means of the spring member 16 shown in FIG. 1 into an idle and operating position, in which the capsule 11 is covered by the cover 3 within the outwardly open peripherally situated reception space 1.
  • a cutting device comprising two small blades 12, fastened on the cover 3 and guided in slots 18 of the case, engages the reception space 1 and cuts or pricks two small holes 13 into the capsule l1 situated therein, close to the two extremities of the capsule.
  • the blades 12 movable in slots 18 incorporated along the periphery simultaneously act as axial bearers for the cylindrical sleeve of the case, which is constructed as a cover.
  • the pricking-open position of the inhalator is shown in FIG. 4.
  • the cover 3 As a consequence of the spring force of the spring member 16, acting at two sides, the cover 3 is moved automatically into the idle and operating position after it has been released. During inhalation, the pulverulent substance present within the capsule 11 is sucked into the mouth as a consequence of the holes 13, via the mouthpiece 17, an inlet opening 14 connected to the reception space 1 and an outlet opening which is open towards the mouthpiece 17, as illustrated in FIG. 1. To eject the empty capsule 11, the cover 3 is brought into the filling and emptying position against the spring force of the spring member 16, the stop pin 6 and the ejector 10 then being moved towards as a consequence of the spring force of the spring member 9, and the ejector ejects the capsule automatically.
  • the bottom of the inhalator which is not shown in the drawings, is equipped with air entry slots for the inlet opening 14 and is inset into the cylindrically formed cover 3, may be constructed in pot-like form close to the axis and may be equipped with a groove in order to act as a receptor and partially as an entraining element for the spring member 16.
  • the cover 3 is transparent thus making it possible to ascertain directly whether a fresh unopened capsule has been inserted. Moreover, it becomes immediately apparent whether the cover 3 is being displaced in the right direction.
  • the cover may be constructed as a closed slide matching the shape of the case. This slider may be displaced either in the direction along the periphery or in axially parallel direction.
  • the cover may also be made in the form of a lid which is removable or secured by hinges.
  • An inhalator for pulverulent substances comprising an inhalator case having an inlet and an outlet for passing respiratory air, a reception space formed on the outer periphery of the case for insertably receiving a rupturable capsule containing a pulverulent substance, means for mounting a cover portion on the inhalator case for movement with respect thereto between a first position whereat the cover portion encloses the capsule in the reception space and a second position at which the cover portion uncovers the capsule in the reception space to permit removal and replacement thereof.
  • An inhalator as claimed in claim 1 further comprising opening means to open a capsule in the reception space, said opening means being mounted to said cover portion to be moved together therewith into said reception space.
  • said means for mounting said cover portion on the inhalator case for movement with respect thereto includes a spring member under the biasing force of which said cover portion is moved from said first position, into said second position and also into a third position at which said opening means enters said reception space.
  • said spring member is a spring coil
  • a stud member being provided on the base of said sleeve to seat the coil spring which engages co-axially in the case.

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  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Veterinary Medicine (AREA)
  • Medical Preparation Storing Or Oral Administration Devices (AREA)
  • Nozzles (AREA)
  • Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
  • Packaging Of Annular Or Rod-Shaped Articles, Wearing Apparel, Cassettes, Or The Like (AREA)
  • Medicinal Preparation (AREA)
  • Developing Agents For Electrophotography (AREA)
  • Toys (AREA)
  • Filling Or Emptying Of Bunkers, Hoppers, And Tanks (AREA)
US506611A 1973-09-18 1974-09-16 Inhalator for pulverulent substances Expired - Lifetime US3918451A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2346914A DE2346914C3 (de) 1973-09-18 1973-09-18 Inhalator für pulverförmige Substanzen

Publications (1)

Publication Number Publication Date
US3918451A true US3918451A (en) 1975-11-11

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Family Applications (1)

Application Number Title Priority Date Filing Date
US506611A Expired - Lifetime US3918451A (en) 1973-09-18 1974-09-16 Inhalator for pulverulent substances

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US (1) US3918451A (xx)
JP (1) JPS5841067B2 (xx)
AT (1) AT342188B (xx)
BE (1) BE820056A (xx)
BG (1) BG21587A3 (xx)
CA (1) CA1027448A (xx)
CH (1) CH570807A5 (xx)
CS (1) CS185569B2 (xx)
DD (1) DD114224A5 (xx)
DE (1) DE2346914C3 (xx)
DK (1) DK154473C (xx)
ES (1) ES430158A1 (xx)
FI (1) FI56119C (xx)
FR (1) FR2243707B1 (xx)
GB (1) GB1472650A (xx)
HU (1) HU171644B (xx)
IE (1) IE40176B1 (xx)
IL (1) IL45657A (xx)
IT (1) IT1021401B (xx)
NL (1) NL176230C (xx)
NO (1) NO135563C (xx)
PH (1) PH11772A (xx)
PL (1) PL91694B1 (xx)
RO (1) RO69308A (xx)
SE (1) SE415230B (xx)
SU (1) SU550107A3 (xx)
YU (1) YU36258B (xx)
ZA (1) ZA745795B (xx)

Cited By (57)

* Cited by examiner, † Cited by third party
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US4013075A (en) * 1974-07-15 1977-03-22 I.S.F. S.P.A. Inhalers and insufflators having a cutting means
US4117844A (en) * 1976-02-11 1978-10-03 Allen & Hanburys Limited Device for dispensing medicaments
US4860740A (en) * 1980-10-30 1989-08-29 Riker Laboratories, Inc. Powder inhalation device
US4889114A (en) * 1983-12-17 1989-12-26 Boehringer Ingelheim Kg Powdered pharmaceutical inhaler
DE3927170A1 (de) * 1989-08-17 1991-02-21 Boehringer Ingelheim Kg Inhalator
US5048514A (en) * 1989-07-07 1991-09-17 Somova S.P.A. Inhaler for medicaments contained in capsules
US5152284A (en) * 1989-02-23 1992-10-06 Phidea S.P.A. Disposable inhaler with pre-pierced capsule
US5320095A (en) * 1990-12-10 1994-06-14 Pharmachemie B.V. Device for use with the inhalation of powdered materials contained in rod-shaped capsules
US5476093A (en) * 1992-02-14 1995-12-19 Huhtamaki Oy Device for more effective pulverization of a powdered inhalation medicament
US5483954A (en) * 1994-06-10 1996-01-16 Mecikalski; Mark B. Inhaler and medicated package
US5505194A (en) * 1994-03-23 1996-04-09 Abbott Laboratories Aerosol inhalation device having slideably and rotatably connected elliptical cylinder portions
US5584285A (en) * 1995-06-07 1996-12-17 Salter Labs Breathing circuit apparatus for a nebulizer
US5619985A (en) * 1994-08-08 1997-04-15 Unisia Jecs Corporation Inhaler type medicine administering device
US5647349A (en) * 1995-06-01 1997-07-15 Unisia Jecs Corporation Medicine administering inhaling device
US5690101A (en) * 1995-07-14 1997-11-25 Kutta; Helmuth W. Portable air purifier with chemical reaction zone
US5752505A (en) * 1996-03-21 1998-05-19 Unisia Jecs Corporation Inhalation-type medicine delivery device
WO1999062495A3 (en) * 1998-06-04 2000-02-10 Inhale Therapeutic Syst Dry powder dispersing apparatus and methods for their use
US6089228A (en) * 1994-09-21 2000-07-18 Inhale Therapeutic Systems Apparatus and methods for dispersing dry powder medicaments
US6470884B2 (en) 1996-01-29 2002-10-29 Aventis Pharma Limited Capsule opening arrangement for use in a powder inhaler
US6575160B1 (en) 1997-08-07 2003-06-10 Art Slutsky Inhalation device
US20030131847A1 (en) * 2002-01-16 2003-07-17 Fabrizio Niccolai Device usable in the treatment of affections of the airways
US6679255B2 (en) * 2001-03-01 2004-01-20 Ivo E. Pera Inhaling device for dispensing powdered medicaments contained in a capsule through the respiratory tract
US6679256B2 (en) 1999-12-17 2004-01-20 Nektar Therapeutics Systems and methods for extracting powders from receptacles
US6681767B1 (en) 1991-07-02 2004-01-27 Nektar Therapeutics Method and device for delivering aerosolized medicaments
WO2004056413A1 (en) * 2002-12-20 2004-07-08 Acrux Dds Pty Ltd Dispensing device
US20040149283A1 (en) * 2002-12-12 2004-08-05 Boehringer Ingelheim Pharma Gmbh & Co. Kg Powder inhaler comprising a chamber for a capsule for taking up a non-returnable capsule being filled with an active ingredient
US20040206350A1 (en) * 2002-12-19 2004-10-21 Nektar Therapeutics Aerosolization apparatus with non-circular aerosolization chamber
US20050150492A1 (en) * 2003-04-09 2005-07-14 Nektar Therapeutics Aerosolization apparatus with air inlet shield
US20050279349A1 (en) * 1991-07-02 2005-12-22 Patton John S Method and device for delivering aerosolized medicaments
WO2006051300A1 (en) * 2004-11-10 2006-05-18 Cipla Limited Inhaler
WO2006066363A1 (en) * 2004-12-23 2006-06-29 Acrux Dds Pty Ltd Dispensing device
EP1941868A2 (en) 2000-02-28 2008-07-09 PharmaKodex Limited Improvements in or relating to the delivery of oral drugs
AU2003291850B2 (en) * 2002-12-20 2009-02-26 Acrux Dds Pty Ltd Dispensing device
US20090183744A1 (en) * 2008-01-22 2009-07-23 Paul Graham Hayton Hand-Held dispensing device
US20090211576A1 (en) * 2007-10-02 2009-08-27 Timo Lehtonen Safety and abuse deterrent improved device
US20100275917A1 (en) * 2007-07-20 2010-11-04 Boehringer Ingelheim International Gmbh Powder inhaler
US8869794B1 (en) 2003-04-09 2014-10-28 Novartis Pharma Ag Aerosolization apparatus with capsule puncturing member
US10022237B2 (en) 2011-08-23 2018-07-17 Linares Medical Devices, Llc Multi-component implant assembly with dual articulating and/or rotating surfaces
USD858869S1 (en) 2016-02-08 2019-09-03 Juul Labs, Inc. Vaporizer cartridge
USD861975S1 (en) 2016-02-08 2019-10-01 Juul Labs, Inc. Vaporizer device with cartridges
US10638792B2 (en) 2013-03-15 2020-05-05 Juul Labs, Inc. Securely attaching cartridges for vaporizer devices
US10653186B2 (en) 2013-11-12 2020-05-19 VMR Products, LLC Vaporizer, charger and methods of use
US10667560B2 (en) 2013-12-23 2020-06-02 Juul Labs, Inc. Vaporizer apparatus
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US10709173B2 (en) 2014-02-06 2020-07-14 Juul Labs, Inc. Vaporizer apparatus
US10865001B2 (en) 2016-02-11 2020-12-15 Juul Labs, Inc. Fillable vaporizer cartridge and method of filling
US10912333B2 (en) 2016-02-25 2021-02-09 Juul Labs, Inc. Vaporization device control systems and methods
US10912331B2 (en) 2013-12-23 2021-02-09 Juul Labs, Inc. Vaporization device systems and methods
US11019685B2 (en) 2014-02-06 2021-05-25 Juul Labs, Inc. Vaporization device systems and methods
WO2021241921A1 (ko) * 2020-05-28 2021-12-02 제이디코스파마 주식회사 약제 기화 흡입기
USD943159S1 (en) 2019-11-14 2022-02-08 Juul Labs, Inc. Component for a vaporizer cartridge
USD943161S1 (en) 2019-11-14 2022-02-08 Juul Labs, Inc. Vaporizer device
USD943158S1 (en) 2019-11-14 2022-02-08 Juul Labs, Inc. Vaporizer cartridge
USD943160S1 (en) 2019-11-14 2022-02-08 Juul Labs, Inc. Vaporizer device
USRE49114E1 (en) 2011-06-28 2022-06-28 Juul Labs, Inc. Electronic cigarette with liquid reservoir
US11517686B2 (en) * 2016-12-20 2022-12-06 Emphasys Importadora Exportadora E Distribuidora Ltda. Dry powder inhaler
US12127602B2 (en) 2021-07-02 2024-10-29 Vmr Products Llc Vaporizer

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GB1562732A (en) * 1976-02-10 1980-03-12 Allen & Hanburys Ltd Device for dispensing medicaments
GB1598081A (en) * 1977-02-10 1981-09-16 Allen & Hanburys Ltd Inhaler device for dispensing medicaments
DK154869C (da) * 1977-02-10 1989-05-16 Allen & Hanburys Ltd Inhalationsapparat til administrering af medikamenter
DE3050005A1 (de) * 1979-10-30 1982-03-18 Riker Laboratories Inc Breath actuated devices for administering powdered medicaments
US4777962A (en) * 1986-05-09 1988-10-18 Respitrace Corporation Method and apparatus for distinguishing central obstructive and mixed apneas by external monitoring devices which measure rib cage and abdominal compartmental excursions during respiration
GB2253200A (en) * 1991-02-01 1992-09-02 Harris Pharma Ltd Inhalation apparatus and fracturable capsule for use therewith
US5797391A (en) * 1991-03-28 1998-08-25 Rhone-Poulenc Rorer Limited Inhaler
US5896855A (en) * 1992-12-24 1999-04-27 Rhone-Poulenc Rorer Limited Multi dose inhaler apparatus
GB0507711D0 (en) 2005-04-15 2005-05-25 Vectura Group Plc Improved blister piercing
EP2058024B1 (en) * 2006-08-31 2019-11-27 Hitachi Automotive Systems Measurement, Ltd. Medicine sprayer
JP2011507593A (ja) 2007-12-20 2011-03-10 アストラゼネカ・アクチエボラーグ 粉末８５４を脱凝集解体する装置ならびに方法
GB0901520D0 (en) 2009-01-30 2009-03-11 Vectura Delivery Devices Ltd Inhaler
EP2448623B1 (en) 2009-07-01 2017-12-20 AstraZeneca AB Dispenser and method for entraining powder in an airflow
GB201301192D0 (en) 2013-01-23 2013-03-06 Vectura Delivery Devices Ltd A blister piercing element for a dry powder inhaler

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Cited By (109)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4013075A (en) * 1974-07-15 1977-03-22 I.S.F. S.P.A. Inhalers and insufflators having a cutting means
US4117844A (en) * 1976-02-11 1978-10-03 Allen & Hanburys Limited Device for dispensing medicaments
US4860740A (en) * 1980-10-30 1989-08-29 Riker Laboratories, Inc. Powder inhalation device
US4889114A (en) * 1983-12-17 1989-12-26 Boehringer Ingelheim Kg Powdered pharmaceutical inhaler
US5152284A (en) * 1989-02-23 1992-10-06 Phidea S.P.A. Disposable inhaler with pre-pierced capsule
US5048514A (en) * 1989-07-07 1991-09-17 Somova S.P.A. Inhaler for medicaments contained in capsules
WO1991002558A1 (de) * 1989-08-17 1991-03-07 Boehringer Ingelheim Kg Inhalator
DE3927170A1 (de) * 1989-08-17 1991-02-21 Boehringer Ingelheim Kg Inhalator
AU645986B2 (en) * 1989-08-17 1994-02-03 Boehringer Ingelheim International Gmbh Inhalator
US5320095A (en) * 1990-12-10 1994-06-14 Pharmachemie B.V. Device for use with the inhalation of powdered materials contained in rod-shaped capsules
US6681767B1 (en) 1991-07-02 2004-01-27 Nektar Therapeutics Method and device for delivering aerosolized medicaments
US20050279349A1 (en) * 1991-07-02 2005-12-22 Patton John S Method and device for delivering aerosolized medicaments
US5476093A (en) * 1992-02-14 1995-12-19 Huhtamaki Oy Device for more effective pulverization of a powdered inhalation medicament
US5505194A (en) * 1994-03-23 1996-04-09 Abbott Laboratories Aerosol inhalation device having slideably and rotatably connected elliptical cylinder portions
US5575281A (en) * 1994-06-10 1996-11-19 Mecikalski; Mark B. Medicated package
US5568807A (en) * 1994-06-10 1996-10-29 Mecikalski; Mark B. Air-flow control for an inhaler
US5483954A (en) * 1994-06-10 1996-01-16 Mecikalski; Mark B. Inhaler and medicated package
US5619985A (en) * 1994-08-08 1997-04-15 Unisia Jecs Corporation Inhaler type medicine administering device
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JPS5841067B2 (ja) 1983-09-09
ZA745795B (en) 1975-10-29
FR2243707A1 (xx) 1975-04-11
IE40176L (en) 1975-03-18
DK488474A (xx) 1975-05-26
AU7326274A (en) 1976-03-18
FI56119C (fi) 1979-12-10
NL7412350A (nl) 1975-03-20
DK154473B (da) 1988-11-21
CS185569B2 (en) 1978-10-31
CA1027448A (en) 1978-03-07
SU550107A3 (ru) 1977-03-05
BE820056A (fr) 1975-01-16
HU171644B (hu) 1978-02-28
YU36258B (en) 1982-06-18
GB1472650A (en) 1977-05-04
RO69308A (ro) 1981-08-17
SE415230B (sv) 1980-09-22
ATA748374A (de) 1977-07-15
CH570807A5 (xx) 1975-12-31
PL91694B1 (xx) 1977-03-31
BG21587A3 (bg) 1976-07-20
DD114224A5 (xx) 1975-07-20
IL45657A (en) 1976-12-31
DE2346914B2 (de) 1980-02-28
NO743294L (xx) 1975-04-14
FR2243707B1 (xx) 1978-08-11
FI271974A (xx) 1975-03-19
PH11772A (en) 1978-06-27
FI56119B (fi) 1979-08-31
IT1021401B (it) 1978-01-30
NO135563C (xx) 1977-04-27
DE2346914A1 (de) 1975-04-17
NL176230C (nl) 1985-03-18
YU252374A (en) 1981-08-31
DK154473C (da) 1989-04-10
SE7411700L (xx) 1975-03-19
DE2346914C3 (de) 1980-10-16
IE40176B1 (en) 1979-03-28
IL45657A0 (en) 1974-11-29
AT342188B (de) 1978-03-28
NO135563B (xx) 1977-01-17
ES430158A1 (es) 1976-10-16
JPS5056789A (xx) 1975-05-17

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