US3895022A - Anti-inflammatory agents, cosmetic preparations and method of preventing inflammation - Google Patents
Anti-inflammatory agents, cosmetic preparations and method of preventing inflammation Download PDFInfo
- Publication number
- US3895022A US3895022A US318757A US31875772A US3895022A US 3895022 A US3895022 A US 3895022A US 318757 A US318757 A US 318757A US 31875772 A US31875772 A US 31875772A US 3895022 A US3895022 A US 3895022A
- Authority
- US
- United States
- Prior art keywords
- benzoxazole
- carboxylic acid
- ester
- melting point
- acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/04—Topical preparations for affording protection against sunlight or other radiation; Topical sun tanning preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/52—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings condensed with carbocyclic rings or ring systems
- C07D263/54—Benzoxazoles; Hydrogenated benzoxazoles
- C07D263/58—Benzoxazoles; Hydrogenated benzoxazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/002—Aftershave preparations
Definitions
- EXAMPLE 1 Di-ethanolammonium salt of 5-methoxybenzoxazole-2-carboxylic acid 7.8 gm of 5-methoxy-benzoxazole-2-carboxylic acid were stirred in ml of methanol with 5.0 gm of diethanolamine at room temperature. The methanol was distilled off from the solution formed, the oily residue was taken up in a little acetone, cooled to 0to 5C, and the di-ethanolammonium salt which crystallized out was filtered off. 9.7 gm (80.5% of theory) of the salt of melting point 95-99C were obtained.
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Cosmetics (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE2164851A DE2164851A1 (de) | 1971-12-27 | 1971-12-27 | Entzuendungshemmer fuer kosmetische praeparationen |
Publications (1)
Publication Number | Publication Date |
---|---|
US3895022A true US3895022A (en) | 1975-07-15 |
Family
ID=5829372
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US318757A Expired - Lifetime US3895022A (en) | 1971-12-27 | 1972-12-27 | Anti-inflammatory agents, cosmetic preparations and method of preventing inflammation |
Country Status (9)
Country | Link |
---|---|
US (1) | US3895022A (es) |
JP (1) | JPS4872340A (es) |
BE (1) | BE793341A (es) |
BR (1) | BR7209119D0 (es) |
DE (1) | DE2164851A1 (es) |
ES (3) | ES410019A1 (es) |
FR (1) | FR2165996B1 (es) |
GB (1) | GB1405776A (es) |
NL (1) | NL7216060A (es) |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4116928A (en) * | 1974-07-01 | 1978-09-26 | Eastman Kodak Company | Heterocylic ester, ultraviolet stabilizers and their use in organic compositions |
US4298742A (en) * | 1980-05-12 | 1981-11-03 | Usv Pharmaceutical Corporation | Esters of benzoxa(thia)zole-2-carboxylic acids |
DE3102907A1 (de) * | 1980-03-19 | 1982-04-08 | Hokko Chemical Industry Co. Ltd., Tokyo | "benzoxazolonderivate, verfahren zur herstellung derselben sowie zubereitungen, die diese derivate enthalten" |
US4405633A (en) * | 1982-03-01 | 1983-09-20 | Usv Pharmaceutical Corporation | Method of treatment of asthma |
US4620010A (en) * | 1984-03-29 | 1986-10-28 | Usv Pharmaceutical Corp. | Process for preparing carboalkoxy substituted benzoxazole compounds |
Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3641029A (en) * | 1970-02-02 | 1972-02-08 | American Cyanamid Co | Substituted benzoxazolecarboxamides and benzothiazolecarboxamides |
-
0
- BE BE793341D patent/BE793341A/xx unknown
-
1971
- 1971-12-27 DE DE2164851A patent/DE2164851A1/de active Pending
-
1972
- 1972-11-27 NL NL7216060A patent/NL7216060A/xx unknown
- 1972-12-21 GB GB5922572A patent/GB1405776A/en not_active Expired
- 1972-12-22 FR FR7246017A patent/FR2165996B1/fr not_active Expired
- 1972-12-25 JP JP47129429A patent/JPS4872340A/ja active Pending
- 1972-12-26 BR BR9119/72A patent/BR7209119D0/pt unknown
- 1972-12-26 ES ES410019A patent/ES410019A1/es not_active Expired
- 1972-12-26 ES ES410018A patent/ES410018A1/es not_active Expired
- 1972-12-26 ES ES410017A patent/ES410017A1/es not_active Expired
- 1972-12-27 US US318757A patent/US3895022A/en not_active Expired - Lifetime
Patent Citations (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3641029A (en) * | 1970-02-02 | 1972-02-08 | American Cyanamid Co | Substituted benzoxazolecarboxamides and benzothiazolecarboxamides |
Cited By (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4116928A (en) * | 1974-07-01 | 1978-09-26 | Eastman Kodak Company | Heterocylic ester, ultraviolet stabilizers and their use in organic compositions |
DE3102907A1 (de) * | 1980-03-19 | 1982-04-08 | Hokko Chemical Industry Co. Ltd., Tokyo | "benzoxazolonderivate, verfahren zur herstellung derselben sowie zubereitungen, die diese derivate enthalten" |
US4298742A (en) * | 1980-05-12 | 1981-11-03 | Usv Pharmaceutical Corporation | Esters of benzoxa(thia)zole-2-carboxylic acids |
US4405633A (en) * | 1982-03-01 | 1983-09-20 | Usv Pharmaceutical Corporation | Method of treatment of asthma |
US4620010A (en) * | 1984-03-29 | 1986-10-28 | Usv Pharmaceutical Corp. | Process for preparing carboalkoxy substituted benzoxazole compounds |
Also Published As
Publication number | Publication date |
---|---|
JPS4872340A (es) | 1973-09-29 |
GB1405776A (en) | 1975-09-10 |
FR2165996B1 (es) | 1975-11-28 |
BE793341A (fr) | 1973-06-27 |
DE2164851A1 (de) | 1973-07-05 |
BR7209119D0 (pt) | 1973-11-01 |
FR2165996A1 (es) | 1973-08-10 |
ES410018A1 (es) | 1975-12-01 |
ES410017A1 (es) | 1975-12-01 |
ES410019A1 (es) | 1975-12-01 |
NL7216060A (es) | 1973-06-29 |
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