US3878846A - Hypodermic syringe with parts disposable after use - Google Patents

Hypodermic syringe with parts disposable after use Download PDF

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Publication number
US3878846A
US3878846A US308844A US30884472A US3878846A US 3878846 A US3878846 A US 3878846A US 308844 A US308844 A US 308844A US 30884472 A US30884472 A US 30884472A US 3878846 A US3878846 A US 3878846A
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US
United States
Prior art keywords
syringe
head
rod
gripping element
rings
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
US308844A
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English (en)
Inventor
Henri Rimbaud
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratoire Spad
Original Assignee
Laboratoire Spad
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Filing date
Publication date
Application filed by Laboratoire Spad filed Critical Laboratoire Spad
Priority to US05/475,146 priority Critical patent/US3930499A/en
Application granted granted Critical
Publication of US3878846A publication Critical patent/US3878846A/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/31—Details
    • A61M5/3129—Syringe barrels
    • A61M5/3137—Specially designed finger grip means, e.g. for easy manipulation of the syringe rod
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M2005/2403—Ampoule inserted into the ampoule holder
    • A61M2005/2407—Ampoule inserted into the ampoule holder from the rear
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M5/2455—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic with sealing means to be broken or opened
    • A61M5/2466—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic with sealing means to be broken or opened by piercing without internal pressure increase
    • A61M2005/247—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic with sealing means to be broken or opened by piercing without internal pressure increase with fixed or steady piercing means, e.g. piercing under movement of ampoule
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178—Syringes
    • A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
    • A61M2005/2485—Ampoule holder connected to rest of syringe
    • A61M2005/2488—Ampoule holder connected to rest of syringe via rotation, e.g. threads or bayonet
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/58—Means for facilitating use, e.g. by people with impaired vision
    • A61M2205/586—Ergonomic details therefor, e.g. specific ergonomics for left or right-handed users

Definitions

  • ABSTRACT A hypodermic syringe of the kind comprising an assemblable syringe head and syringe body; a protective case for the syringe body; a cartridge containing a dose of anaesthetic intended for support in the syringe body; and a sterilization and presentation support for the syringe body, cases and cartridges.
  • the hypodermic syringe having a head with a tip adapted for connection to the body, a rod slidingly mounted in the axial direction in the tip, gripping elements fixed to the tip and to the exterior free end of the rod, the body being hollow, and adapted to receive a cartridge of anaesthetic, having at one end threads for being fixed to the tip and adapted at the other end to receive a double needle holder, the gripping element fixed to the tip being mounted on the latter adjustably in the longitudinal direction with respect to the gripping element fixed to the exterior end of the rod.
  • Syringes particularly those used by dentists, are known which comprise a syringe head for permanent use, a syringe body supplied in sterile condition and disposable after use, and a cartridge containing an anaesthetic devised to be placed in the body of the syringe for the purpose of an injection.
  • the bodies and the cartridges are supplied in packages which the user has to open, and from which he has to take the articles directly with his fingers. Furthermore, the cartridges are not perfectly sterile and the user frequently has to sterilize the crimped joint which blocks one end of the cartridge and through which the anaesthetic is removed.
  • An object of the present invention is to provide a syringe comprising a head which is suitable for all users irrespective ofthe size of their hand, and a syringe body supplied in sterile condition which is fitted on to the head simply and rapidly without being touched by the fingers.
  • a further object of the invention is to provide a syringe comprising a body disposable after use with which the known conventional cartridges of anaes thetic can be used as well as novel cartridges specially appropriate to the syringe of the invention and providing absolute guarantee of asepsis without the necessity of an additional sterilization at the time of their use.
  • Yet a further object of the invention is to provide a syringe with a permanent head and with body supplied in a sterile condition which may be disposed of after use but with which a plurality of injections can nevertheless be made successively by replacing the empty anaesthetic cartridge by a full cartridge.
  • a still further object of the invention is to provide a syringe with body disposable after use using anaesthetic cartridges supplied in a sterile condition with which the suction after driving the needle into the flesh, in order to verify whether the point of said needle is located in a blood vessel can be performed automatically by means of a simple relaxation of the pressure exerted upon the liquid to be injected.
  • Another object of the invention is to provide a package and a support for the body and for the cartridges supplied sterile which will ensure that asepsis is maintained during the delivery and the storage of said articles and permitting them to be fitted on to the head of the syringe without being touched by fingers.
  • a hypodermic syringe of the kind comprising an assemblable syringe head and syringe body, the head having a tip adapted for connection to the body. a rod slidingly mounted in the axial direction in the tip, gripping elements fixed to the tip, and to the exterior free end of the rod.
  • the body being hollow, and adapted to receive a cartridge of anaesthetic, having at one end means for being fixed to the tip and adapted at the other end to receive a double needle holder.
  • the gripping element fixed to the tip being mounted. on the latter adjustably in the longitudinal direction with respect to the grip ping element fixed to the exterior end of the rod.
  • the tip comprises a sleeve in which the rod slides, rings being stacked on the said sleeve, locking means for the rings in the axial direction being fitted at one end of the sleeve.
  • the gripping element being constituted by a disc interposed between two rings ofthe set of rings, the locking means being demountable to enable the disc to beinterposed between any two other rings.
  • a second disc is interposed between the rings at a point remote from the first disc.
  • the two discs may have a frustoconical profile, one being flared towards the gripping element fixed to the rod and the other being flared in the opposite direction.
  • the gripping element may comprise two spaced double lugs interposed between the stacked rings and clamped along a sleeve in which the rod slides.
  • the group of gripping elements may comprise two spaced double lugs each fitted with a locking screw and mounted slidingly in the axial direction along a sleeve in which the rod slides.
  • the tip is preferably fitted with a screwthread for fixing connections to the body, the body suitably being of moulded material and in the form of a hollow tube having an open end provided with a screwthread complementary to that of the tip. and at its opposite end a blocking wall, the needle protruding internally and externally and being anchored in the blocking wall, the hollow tubular body being adapted to receive a cartridge containing a dose of anaesthetic.
  • a syringe body comprising a hollow tube having an open end fitted with means for fixture to a syringe head and at its opposite end a blocking wall. a needle which protrudes internally and externally being anchored in the blocking wall, the hollow tubular body being adapted to receive a cartridge containing a dose of anaesthetic.
  • the body of the syringe is supplied in sterile condition in a protective case constituted by a hollow tubular element which fits snugly upon the external face of the body, one end of said element being blocked by a solid wall, the length of the case being such that when the body in introduced therein the fixing means e.g. a screwthread of the latter remains free and the needle which protrudes outside the body is shielded in fluid tight relation inside the case without contact with the internal faces of the latter.
  • the case may be provided internally with a stop which corresponds to a stop provided externally on the body so that the case enables the body when introduced therein to be driven in rotation in both directions.
  • the internal face of the case has a profile which is not of revolution corresponding to a similar profile of the external face of the body of the syringe.
  • a cartridge containing a dose of anaesthetic comprising a tube of constant section fitted at one end with a fluid tight piston displaceable inside the tube and at the opposite end with a plug of elastic material comprising a first part fitting the interior of the tube and a second part external to the tube which covers the extreme portion of the latter and whose external dimension is greater than the internal dimension of the body of the syringe so that the plug exerts a friction force against the internal face of the body and opposes the free sliding of the cartridge in the body.
  • the first part of the plug fitting the interior of the tube of the cartridge may have thin walls such that said first part is crushed elastically by the pressure of the liquid in course of injection.
  • the plug may have a blind cavity which opens at the exterior extreme face of the second part of said plug and which extends inside the first part.
  • the syringe of the present invention may be used with conventional anaesthetic cartridges having crimped joints.
  • the rod slidingly mounted in the axial direction in the tip of the head is anchored in rotation with respect of said tip.
  • the free end of said rod being provided with a screwthread which corresponds to the interior screwthread of the piston of conventional anaesthetic cartridges with a crimped joint.
  • the internal face of the body using in such a syringe may be fitted with lamellae which retain the cartridge in position.
  • the syringe bodies introduced into the cases and containing or not containing a cartridge of anaesthetic. and the cartridge supplied in sterile condition, may be supplied upon a sterilization and presentation support which comprises a base upon which is rests and a wall extending from the said base and de-limiting a cell adapted to receive. with friction and an air-tight seal an extreme part of one of the elements case or cartridge. said extreme part being. on a case containing a syringe body equipped with a cartridge. its free and open extreme part through which the screwthread of the syringe body protrudes. and on a cartridge alone, the extreme part opposite to that which is blocked by a piston.
  • Each cell may be provided with an internal stop which limits the insertion of the case or cartridge element.
  • an aperture is provided in the extreme blocking wall which carries the double needle.
  • FIG. 1 is a vertical cross-section through a syringe fitted with a syringe body containing an anaesthetic cartridge and shielded by a protective case;
  • FIG. 2 is a vertical cross-section through a syringe body containing a cartridge prior to its assembly with the head of a syringe;
  • FIG. 3 is a section similar to FIG. 2, the case being arranged in a protective support;
  • FIG. 4 is a section along the line IVIV of FIG. 1;
  • FIG. 5 is a cross-section through a support with multiple cells for cases containing a syringe body and a cartridge with a syringe and a cartridge disposed in one cell;
  • FIGS. 6 and 7 are cross-section elevations showing a cartridge according to the invention and a conventional 4 cartridge each arranged on an individual support; and FIG. 8 is a cross-sectional elevation of a support with multiple cells for cartridges with a conventional cartridge provided with a piston with screwthread shown part in section.
  • FIG. 1 shows a hypodermic syringe with a syringe head designated by the reference 1, and a syringe body designated by the reference 2.
  • Thehead comprises a tip 3 having at one end an internal screwthread and prolonged at the opposite end by a sleeve 4 in which a rod 5 slides.
  • the rod 5 is provided at its end with a ring 10 large enough for the passage of a thumb.
  • the disc 9 and the ring 10 constitute a set of gripping elements which are used to give an injection, the index and second fingers being braced against the disc 9 while the thumb is engaged in the ring 10.
  • the gripping element fixed to the tip that is to say the disc 9 can easily be moved along the sleeve 4 in order to regulate the distance of said elements as a function of the size of the operator's hand.
  • the disc 8 likewise adjustable in position. enables the syringe to be grasped more easily between the index and second fingers which may be slid between the two discs 8 and 9.
  • the syringe body 2 may be fabricated of moulded material for example of injection moulded plastics. It is supplied in sterile condition and intended to be disposable after use. It is constituted by a hollow tube having an open end fitted with a screwthread 11 complementary to that of the tip 3. The opposite end is closed by a transverse blocking wall 12 pierced with a rather small off-center hole 13.
  • a double needle which has an internally protruding part 14 and an externally protruding part 15.
  • the body 2 is protected for its delivery and its storage inside a case 16.
  • the latter is a hollow tubular element mouled of plastic material, preferably of polyethylene, which fits snugly and air-tight upon the external face of the body. One end of the element is blocked by a solid wall 17. Its length is such that when the body is introduced into it. the screwthread 11 remains free whereas the entire remainder of the body including the needle 15 is shielded fluid tightly.
  • the body 2 is fitted externally with at least one stop 18.
  • the case 16 is fitted internally with four stops l9 situate in the same sectional plane as the stops l8.
  • the stops l8 and 19 come into contact as a result of a relative movement in rotation of the case and of the body. It is therefore possible to screw the body 2 onto the tip 3 by holding only the case 16, without having to disengage the body from it.
  • FIGS. 2 and 3 show in detail cartridges containing an anaesthetic, which are generally supplied in sterile condition, arranged inside the body 2.
  • the cartridge of the invention designated by the reference numeral 20, comprises a tube 21 of constant section fitted at one end with a fluid piston 22 displaceable inside the tube and provided at its opposite end with a plug 23 of elastic material, for exampleof rub ber.
  • the plug 23 comprises a first part 24 fitting the interior of the tube and a second part 23 exterior to the tube 21.
  • Said second part 25 covers the extreme portion of the tube 21 and it has externally a dimension for example a diameter which is greater than the interior dimension of the body of the syringe.
  • a blind cavity 26 is provided in the plug 23; it opens into the exterior extreme face of the second part 25 and extends inside the first part 24 of the said plug.
  • the walls of the first part 24 are reduced in thickness and they are capable of being crushed elastically upon themselves.
  • the case-body-cartridge assembly is in the state visible in FIG. 2.
  • the cartridge 20 is anchored in the body 2 by virtue of the friction of the plug 23, at such a depth that the latter is not perforated by the interior part 14 of the needle.
  • a support 27 is provided for use individually (FIG. 3) or grouped with others so as to constitute a multiple celled support (FIG. 5).
  • Each support 27 comprises a base 28 upon which it rests and a wall (FIG. 3) or a plurality of mutually adjacent walls (FIG. 5) which rise from the base and limit one or more cells.
  • the latter are adapted to receive with friction and air-tightly an extreme part of a case containing a body and a cartridge or a body alone.
  • the cartridges 20 of the invention and the conventional cartridges are introduced into their supports by their plug or by their crimped joint which must be pierced by the interior needle 14 of the syringe body.
  • the supports are preferably made of polystyrene, since the contactof these two materials achieves a better fluid tight seal then the contact of identical materials. Furthermore. polyethylene is permeable to ethylene oxide whereas polystyrene is not. Therefore the interior of a complete block like those in FIG. 3 orin FIG; 5 can be sterilized before their assembly. by placing them in an atmosphere of ethylene oxide under pressure. The gas passes through the wall of the case 16, spreads in the support 27 and in the body 2 through the lower aperture and through the upper aperture 13.
  • the supports and the blocks of supports of the invention ensure durably and with certainty the sterility on the one hand of the syringe body and the cartridge, and on the other hand of the plug which will be pierced by the needle.
  • a single movement of the hand is sufficient to take a case-body-cartridge assembly or a cartridge along without having to undertake an additional sterilization.
  • the cartridge 20 is constrained to descend into the body of the syringe and the plug 23 is pierced by the internal needle 14.
  • the case 16 is taken once more, the body 2 is unscrewed, the empty cartridge is thrown away and is replaced by a full cartridge which is extracted from its support and which is introduced into the body 2, as in FIG. 2, without having to grasp it by the plug which must remain sterile.
  • the invention permits the use of a conventional cartridge 29 which has, at its end opposite to the piston 30, a shrinkage 31; the latter serves to fit a crimping capsule 32 with a central orifice which maintains in position a fluid tight seal 33.
  • Some pistons 30 have a screwthreaded blind hole 34.
  • the free end of the rod 5 is screwthreaded like the hole 34 and the rod itself is anchored in rotation inside the sleeve 4 by virtue of a groove and of a lug (not shown).
  • the internal face of the syringe body is equipped with longitudinal lamellae (not shown) which oppose the rotation of the cartridge 29 and which also brake its translation inside the body.
  • the rod 5 is screwed in the plug 30. This permits the verifying suction discussed hereinbefore to be effected by a traction applied to the rod 5.
  • the present invention also embraces those modifications and variants which do not depart from its ambit or from its spirit.
  • the syringe illustrated and described is adapted for use by dentists. but it will be apparent that it is also suitable for other uses.
  • a hypodermic syringe comprising:
  • a syringe head including a tip having an axial bore extending therethrough a hollow sterile syringe body connected to said head.
  • a rod slidably mounted in said bore in said head and including a portion extending externally of said head.
  • a gripping element fixed to said portion of the rod extending externally of the head.
  • a counter-gripping element mounted on said head for adjustably securing said counter-gripping 8 element thereto in an axially adjustable position with respect to said gripping element on said rod, means in said body for storing an injectible solution and operated by displacement of said rod,
  • said tip comprising an elongated sleeve in which the rod slides.
  • said means for adjustably securing said gripping element comprising a set of rings stacked on the said sleeve.
  • a syringe as claimed in claim 1, comprising a second disc interposed between said rings of said set at a point remote from the first disc.
  • a syringe as claimed in claim 1, comprising a second disc interposed between said rings of said set at a point remote from the first disc. the two said discs having a frustoconical profile, one being flared towards the gripping element fixed to the rod and the other being flared in the opposite direction.

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  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)
US308844A 1971-12-13 1972-11-22 Hypodermic syringe with parts disposable after use Expired - Lifetime US3878846A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
US05/475,146 US3930499A (en) 1972-11-22 1974-05-31 Hypodermic syringe with parts disposable after use

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7144606A FR2164955A5 (xx) 1971-12-13 1971-12-13

Related Child Applications (1)

Application Number Title Priority Date Filing Date
US05/475,146 Division US3930499A (en) 1972-11-22 1974-05-31 Hypodermic syringe with parts disposable after use

Publications (1)

Publication Number Publication Date
US3878846A true US3878846A (en) 1975-04-22

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Family Applications (1)

Application Number Title Priority Date Filing Date
US308844A Expired - Lifetime US3878846A (en) 1971-12-13 1972-11-22 Hypodermic syringe with parts disposable after use

Country Status (6)

Country Link
US (1) US3878846A (xx)
JP (1) JPS5710747B2 (xx)
BE (1) BE808454Q (xx)
DE (2) DE2259825B2 (xx)
FR (1) FR2164955A5 (xx)
GB (2) GB1379508A (xx)

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DE2915339A1 (de) * 1979-04-14 1980-11-06 Pajunk Gmbh Feingeraetebau Med Schnellverschluss zur befestigung der betaetigungsgriffe an einem spritzgestell
US4474734A (en) * 1983-07-05 1984-10-02 Microbiological Applications, Inc. Syringe shield and closure sterilization method
US4919657A (en) * 1988-11-14 1990-04-24 Habley Medical Technology Corporation Dental syringe having a medication filled carpule and a retractable needle cannula
US5437647A (en) * 1990-05-09 1995-08-01 Safety Syringes, Inc. Disposable self-shielding aspirating syringe
US5558649A (en) * 1995-01-25 1996-09-24 Shields; Jack W. Conical syringe/needle shield
US5624400A (en) * 1990-05-09 1997-04-29 Safety Syringes, Inc. Disposable self-shielding aspirating syringe
US5976112A (en) * 1997-11-07 1999-11-02 Lyza Weiss Jennings & Shea Injector syringe
US20050187532A1 (en) * 2004-02-24 2005-08-25 Medex, Inc. Diaphragm-based reservoir for a closed blood sampling system
US20060264825A1 (en) * 2005-05-20 2006-11-23 Safety Syringes, Inc. Syringe with needle guard injection device
US20090312714A1 (en) * 2006-07-07 2009-12-17 Insulution Svenska Ab Syringe, capsule device therefore, and syringe device
EP2413995A1 (en) * 2009-03-31 2012-02-08 Sanofi-Aventis Deutschland GmbH Dose button for a drug delivery device and method for manufacturing a dose button

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JPS52132590A (en) * 1976-04-27 1977-11-07 Haabaato Bogeruman Jiyosefu Injector
JPS59178944U (ja) * 1983-05-11 1984-11-29 陳　敏利 ハンガ−
FR2551349B1 (fr) * 1983-09-02 1986-11-28 Spad Lab Etui de protection d'un corps de seringue
GB9125699D0 (en) * 1991-12-03 1992-01-29 Glaxo Group Ltd Device
DE10018827A1 (de) * 2000-04-15 2001-10-25 Vetter & Co Apotheker Spritze für medizinische Zwecke
EP2603264A1 (en) 2010-08-12 2013-06-19 Covidien LP Single use device for delivery of cartridge drugs
EP3268078B1 (en) 2015-03-10 2020-11-04 Regeneron Pharmaceuticals, Inc. Aseptic piercing system
SG11201908539VA (en) 2017-05-05 2019-11-28 Regeneron Pharma Auto-injector
USD1007676S1 (en) 2021-11-16 2023-12-12 Regeneron Pharmaceuticals, Inc. Wearable autoinjector

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US3545427A (en) * 1968-11-27 1970-12-08 George R Ryan Blood-collecting assembly
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US1574579A (en) * 1924-08-30 1926-02-23 Edmund A Jones Syringe
US1840788A (en) * 1929-04-09 1932-01-12 Nevin Mendel Hypodermic syringe and the like
US2607344A (en) * 1951-08-01 1952-08-19 Frederick M Turnbull Syringe assembly
US2728341A (en) * 1951-11-05 1955-12-27 Zbislaw M Roehr Hypodermic syringe
US2778359A (en) * 1954-04-09 1957-01-22 Friedman Benjamin Hypodermic syringe device
US2707954A (en) * 1954-05-05 1955-05-10 Sr John L Kas Dosing syringe
US2895474A (en) * 1955-01-04 1959-07-21 Cook Waite Lab Inc Aspirating cartridge syringe
US2826195A (en) * 1956-05-22 1958-03-11 American Home Prod Plastic injection syringe
US3110309A (en) * 1960-08-15 1963-11-12 Brunswick Corp Plastic cartridge needle assembly
US3115137A (en) * 1962-03-12 1963-12-24 Stanley J Sarnoff Aspiration seal
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US3366103A (en) * 1965-06-24 1968-01-30 Becton Dickinson Co Blood collecting assembly
US3433216A (en) * 1966-12-22 1969-03-18 Roger P Mattson Self-evacuating fluid sampling device
US3494201A (en) * 1968-08-16 1970-02-10 Oxford Lab Pipetting system
US3583399A (en) * 1968-09-03 1971-06-08 Astra Chem Ltd Self-aspirating syringe
US3545427A (en) * 1968-11-27 1970-12-08 George R Ryan Blood-collecting assembly

Cited By (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2915339A1 (de) * 1979-04-14 1980-11-06 Pajunk Gmbh Feingeraetebau Med Schnellverschluss zur befestigung der betaetigungsgriffe an einem spritzgestell
US4474734A (en) * 1983-07-05 1984-10-02 Microbiological Applications, Inc. Syringe shield and closure sterilization method
US4919657A (en) * 1988-11-14 1990-04-24 Habley Medical Technology Corporation Dental syringe having a medication filled carpule and a retractable needle cannula
US5437647A (en) * 1990-05-09 1995-08-01 Safety Syringes, Inc. Disposable self-shielding aspirating syringe
US5624400A (en) * 1990-05-09 1997-04-29 Safety Syringes, Inc. Disposable self-shielding aspirating syringe
USRE37439E1 (en) * 1990-05-09 2001-11-06 Safety Syringes, Inc. Disposable self-shielding aspirating syringe
US5558649A (en) * 1995-01-25 1996-09-24 Shields; Jack W. Conical syringe/needle shield
US5976112A (en) * 1997-11-07 1999-11-02 Lyza Weiss Jennings & Shea Injector syringe
US20050187532A1 (en) * 2004-02-24 2005-08-25 Medex, Inc. Diaphragm-based reservoir for a closed blood sampling system
US20060264825A1 (en) * 2005-05-20 2006-11-23 Safety Syringes, Inc. Syringe with needle guard injection device
US8372044B2 (en) 2005-05-20 2013-02-12 Safety Syringes, Inc. Syringe with needle guard injection device
US20090312714A1 (en) * 2006-07-07 2009-12-17 Insulution Svenska Ab Syringe, capsule device therefore, and syringe device
US8267902B2 (en) 2006-07-07 2012-09-18 Insulution Svenska Ab Syringe, capsule device therefore, and syringe device
EP2413995A1 (en) * 2009-03-31 2012-02-08 Sanofi-Aventis Deutschland GmbH Dose button for a drug delivery device and method for manufacturing a dose button
US10286150B2 (en) 2009-03-31 2019-05-14 Michael Harms Dose button for a drug delivery device and method for manufacturing a dose button
EP2413995B1 (en) * 2009-03-31 2022-09-21 Sanofi-Aventis Deutschland GmbH Dose button for a drug delivery device and method for manufacturing a dose button

Also Published As

Publication number Publication date
DE2264520A1 (de) 1974-06-27
DE2264520C3 (de) 1979-09-06
DE2259825A1 (de) 1973-06-28
GB1379508A (en) 1975-01-02
JPS5710747B2 (xx) 1982-02-27
JPS4876390A (xx) 1973-10-15
DE2264520B2 (de) 1979-01-11
DE2259825B2 (de) 1980-03-13
FR2164955A5 (xx) 1973-08-03
GB1379509A (en) 1975-01-02
BE808454Q (fr) 1974-03-29

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