US3855868A - Multiple pipette - Google Patents

Multiple pipette Download PDF

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Publication number
US3855868A
US3855868A US00328054A US32805473A US3855868A US 3855868 A US3855868 A US 3855868A US 00328054 A US00328054 A US 00328054A US 32805473 A US32805473 A US 32805473A US 3855868 A US3855868 A US 3855868A
Authority
US
United States
Prior art keywords
pistons
containers
scale
sleeve
setting
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
US00328054A
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English (en)
Inventor
O Sudvaniemi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Thermo Fisher Scientific Oy
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FI35872A external-priority patent/FI47460C/fi
Priority claimed from FI167072A external-priority patent/FI51908C/fi
Application filed by Individual filed Critical Individual
Application granted granted Critical
Publication of US3855868A publication Critical patent/US3855868A/en
Assigned to LABSYSTEMS OY reassignment LABSYSTEMS OY ASSIGNMENT OF ASSIGNORS INTEREST. Assignors: SUOVANIEMI, OSMO
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
    • B01L3/02—Burettes; Pipettes
    • B01L3/021—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids
    • B01L3/0217—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids of the plunger pump type
    • B01L3/0224—Pipettes, i.e. with only one conduit for withdrawing and redistributing liquids of the plunger pump type having mechanical means to set stroke length, e.g. movable stops
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1065—Multiple transfer devices

Definitions

  • This invention relates to an improved multiple pipette having inside its body a piston mover rod which is provided with a press button at its upper end and surrounded by a spiral spring which, after the rod has been pressed down, returns the rod to its original position so that liquid is sucked into containers connected with the lower ends of the cylinders and provided with points, and which rod can be pressed down again against the spring force for discharging the liquid from the containers.
  • Pipettes which can be used for pipetting simultaneously several equal samples from'separate receptables into other receptables are previously known.
  • the pistons move down a certain distance to the filling position, and wnen returning up, they suck a certain volume of liquid into the points.
  • the pistons can be pressed down the distance that was required for filling, and then the piston movement can be'carried a small distance further down from the filling position inorder to drain the points completely.
  • the multiple pipette is provided with a scale so that the setting for various volumes is easy and simple.
  • test tube element is an essential part to the multiple pipette according to the invention.
  • the size of the test tube element is such that it can be held by one hand while pipetting into it is done by the other hand.
  • the tubes correspond to the distances between the points of the multiple pipette.
  • test tube element has a size which is such that it can be shaken as a whole by a Rotamixer for instance, so that the liquid in each tube is effectively mixed without being spilled out from the tubes of the test tube element.
  • the test tube element also comprises a lid which simultaneously closes all the tubes of the test tube element. This enables the storing of liquid in the tubes or the shaking of the test tube element by tilting it upside down, for instance.
  • one edge of the test tube element is provided with a mark or a code, made either when casting the element or later. This mark or code enables the recognition of the test tube element either visually, mechanically or electronically. Further, it in-- dicates the position of the test tube element so that the individual tubes can be identified. In this way, the coding of each individual tube is unnecessary.
  • FIG. 4 shows the simultaneous joining of the points to the multiple pipette according to the invention by means of a point supporting plate and an instant joiner
  • FIG. 5 shows a section taken on line B-B in FIG. 4,
  • FIG. 6 shows a side viewof a-test tube element according to the invention, in section
  • FIG. 7 shows a section of the test tube element of FIG. 6, taken on line C C, and
  • FIG. 8 shows the lid of the test tube element, in sectIOII.
  • the multiple pipette comprises two functional sections: a handle section I and a piston section II.
  • the handle section I has a setting portion operated on micrometer screw principle. It also contains parts that transmit the movement of a press button 1 to a piston mover 14' which is common to all pistons.
  • the outer surface of the sleevelike body 3 of the handle section has a thread with a certain pitch, corresponding to the tread on the inner surface of a setting sleeve 4.
  • the outer surface of the body 3 is provided with an axial scale.
  • the inner sur-. face of a locking sleeve 5 also has a thread corresponding to the thread of the body 3. Between thesetting sleeve 4 and the locking sleeve 5 there is a threadless,
  • a sleeve 9 is arranged axially slidably at the upper end of the setting sleeve 4 around the rod 2 of the push button 1.
  • the sleeve 9 is forced to its upper position by a spring 11 between the sleeve 9 and a locking ring 10.
  • the rod 12 of the mover 14 of the piston 17 extends inside the body 3.
  • the rod is forced to its upper position by a spring 13, and at the same time the push button rod 2, which abuts the rod 12, is forced to its upper position.
  • the handle section I is joined by a threaded connection to the upper casing 15 of the piston section II.
  • the micrometer screw scale of the multiple pipette is calibrated by means of I a' screw sleeve 30 (FIG. 4) when assembling the multiple pipette.
  • I a' screw sleeve 30 FIG. 4
  • the sleeve 9 is moved, and the distance a is'changed correspondingly.
  • the liquid volume received atthe points 29 used as liquid containers corresponds to the distance a, and the volume can be read directly on the micrometer screw scale.
  • the casing of the piston section II comprises a flat upper casing and a cylinder casing 16 attached to the lower surface of the uppercasing.
  • the axially moving piston mover 14 common to all the pistons is placed inside the casing and joined by a threaded connection to the rod 12.
  • the pistons 17 are connected with the piston mover 14 either by a common'connection piece 18 as shown in FIG. 1, or each piston separately by a connection piece 19 as shown in FIG. 3.
  • each piston Between the upper end of each piston and the connection piece 18 or the connection pieces 19 there is a clearance so that the pistons 17 should move as fricmover 14, as shown in FIG. 1.
  • the axial movement of the'pi stons in relation to thepiston mover 14 is prevented by springs 21 (FIG. 1) or springs 22 (FIG. 3).
  • Thespring force of a spring 21 is greater than the friction force between a piston and an O-ring 24 at the lower end of the piston.
  • the lower'end of each piston is airtightly closed by a plug 23.
  • the pistons 17 extend parallel into the cylinders 20 inside the cylinder'casing 16.
  • the O-ring seals of the pistons are placed at the upper ends of the cylinders 20.
  • the force of a stay 25 arranged on the O-rings, is adjustable by bolts 26 through springs 27, so that the tightness of the O-rings in relation to the pistons can be adjusted.
  • the parallel cylinders 20 are extended by sleevelike extensions 28.
  • Plastic points 29, which are used as liquid containers when pipetting and which can be changed, are attached to the extensions 28 by pressing.
  • the points 29, used for liquid containers of the multiple pipette are made so that they are fixed in the supporting plate 32 or pressed into the holes in the supporting plate 32.
  • This supporting plate with the tension 28.
  • the points 29 in'the supporting plate are joined air-tightly to the extensions 28 by means of the O-rings 31.
  • the multiple pipette isnow ready for use, and equal, liquid volumes to be transferred can be sucked by means of the pistons 17 into each point.
  • Each point 29 is detached simultaneously together with the. supporting plate when the instant joiner 33 is opened, and the supporting plate can be replaced quickly by another one with clean points.
  • a test tube element shown in FIGS. 6 to 8 is an essential part of the invention.
  • the pipetted liquid volumes are transferred into thistest tube element. It comprises a supporting plate 34 and test tubes 35, either fixed or loose in the plate.
  • the position and the number of the tubes correspond to the position and the number of the points of the multiple pipette.
  • the test tube element can be closed by a lid 36.
  • the lid is provided with plugs 38 which are positioned and made so that they fit tightly at the tops of the corresponding tubes. By means of the lid 36, all the tubes of the test tube element can simultaneously be closed tightly.
  • one edge of the test tube element is provided with a clearly noticeable notch 37, which is made when casting the elementor later.
  • the notch can'be replaced by some other mark, such as number, letter or code, which can be recognized also in some other way than visually.
  • electronic or mechanic regocnition can be applied.
  • the multiple pipette in FIG. 1 comprises nine points 29, at equal distances from each other, and it is possible to transfer desired equal liquid volumes in each point.
  • liquid can be transferred into each test tube of the test tube element shown in FIGS. 6 to 8, or from one test tube element into another one.
  • the construction of the multiple pipette is such that it can be easily handled by one hand.
  • the push button 1 is pressed into the sleeve 9a distance allowed by the primary stroke a, and the'multiple pipette is now ready to be filled.
  • the points 29 of the multiple pipette are then submerged about 1 cm below the liquid surface.
  • the spring 13 through rod 12 forces the piston mover 14 with the pistons 17 to the upper position, and the underpressure in the cylinders 20 causes a liquid volume corresponding to the primary stroke a to be sucked into each point.
  • Discharging of the multiple pipette is done by pressing down the pushbutton 1 the distance a of the primary stroke.
  • the multiple pipette can easily and quickly be set for various volumes by changing the length of the primary stroke.
  • the setting is done by turning the setting sleeve 4 either clockwise or counterclockwise in relation to the body 3 so that the length a of the primary stroke either increases or decreases.
  • the setting sleeve 4 is provided with a fixed scale ring 7 having a scale on its circumference.
  • the body 3 is provided with an axial scale.
  • the scales of the setting sleeve and the body' can be read as a micrometer screw scale. On this principle, the multiple pipette can be set linearly and infinitely, and the volume to be pipetted can be read directly on the micrometer screw scale.
  • the setting sleeve is locked in a desired position by the locking sleeve 5 by turning the locking sleeve tightly against the transparent ring 6 so that the ring is pressed against the setting sleeve 4 and holds it in a desired position.
  • the multiple pipette is ready for use when the setting sleeve is locked in aposition for a desired volume.
  • the operation and the design of the multiple pipette is such that pipetting is not straining.
  • the multiple pipette can be operated by a programmed electric step motor, instead of manually, so that the significance of the primary and secondary strokes of the multiple pipette is taken into account.
  • the number of the points of the multiple pipette and correspondingly the number of the tubes in the test tube element is not necessarily nine,'the number can be either smaller or greater.
  • a multiple pipette comprising a body, a piston rod disposed within the body, a push button attached to one end of the piston rod, a plurality of containers for holding liquid, a plurality of cylinders connected to thecontainers, a plurality of pistons within the cylinders, a plurality of O-rings surrounding the pistons, spiral spring means surrounding the piston rod for returning it to a position in which the containers are filed after the push button has been pressed, and connecting means for connecting the pistonsto the cylinders while permitting sidewaysmovement of the pistons, the connecting means including connecting spring meansthat restrains axial movement of the pistons in relation to the piston rod, said connecting spring means having a force that exceeds the friction force of the O-rings.
  • the apparatus of claim 1 further comprising an O-ring stay for positioning the Orings, a plurality of springs for positioning the O-ring stay, and a plurality of bolts for adjusting the force of the O-ring positioning springs.
  • the apparatus of claim 1 further comprising setting means for adjusting the stroke of the pistons, said setting means including a rotatable setting sleeve, a scale for indicating the adjustment of the setting means and a transparent ring through which the scale can be read.
  • the apparatus of claim 4 further comprising a micrometer scale and calibrating means cooperating with the micrometer scale for changing the volume of each container.

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  • Health & Medical Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Devices For Use In Laboratory Experiments (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
US00328054A 1972-02-10 1973-01-30 Multiple pipette Expired - Lifetime US3855868A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FI35872A FI47460C (fi) 1972-02-10 1972-02-10 Sarjapipetti.
FI167072A FI51908C (fi) 1972-06-13 1972-06-13 Sarjapipetti

Publications (1)

Publication Number Publication Date
US3855868A true US3855868A (en) 1974-12-24

Family

ID=26156311

Family Applications (1)

Application Number Title Priority Date Filing Date
US00328054A Expired - Lifetime US3855868A (en) 1972-02-10 1973-01-30 Multiple pipette

Country Status (10)

Country Link
US (1) US3855868A (nl)
JP (1) JPS5235557B2 (nl)
CA (1) CA952488A (nl)
CH (2) CH556194A (nl)
DE (3) DE2366404C2 (nl)
FR (1) FR2171453B1 (nl)
GB (2) GB1392792A (nl)
IT (1) IT977765B (nl)
NL (2) NL175143C (nl)
SE (2) SE385663B (nl)

Cited By (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4020698A (en) * 1974-10-29 1977-05-03 Marteau D Autry Eric Pipette which may be calibrated
US4054062A (en) * 1976-05-03 1977-10-18 Oxford Laboratories Inc. Hand-held micropipettor with improved accuracy of liquid volumes transferred
US4058370A (en) * 1974-07-05 1977-11-15 Osmo Antero Suovaniemi Apparatus for accurate pipetting of small liquid volumes
US4215092A (en) * 1976-04-08 1980-07-29 Osmo A. Suovaniemi Apparatus for liquid portioning and liquid transferring
US4237095A (en) * 1978-04-25 1980-12-02 Kommandiittiyhtio Finnpipette Osmo A. Suovaniemi Tip vessel for use in connection with a dosage pipette
US4263257A (en) * 1978-09-08 1981-04-21 Metsaele Seppo Juhani Pipette
US4268481A (en) * 1979-03-23 1981-05-19 Kommandittiyhtio Finnpipette Osmo A. Suovaniemi Pipette
US4335621A (en) * 1979-08-31 1982-06-22 Kommandiittiyhtio Finnpipette Osmo A. Suovaniemi Pipette
US4442722A (en) * 1982-02-23 1984-04-17 Beckman Instruments Inc. Plunger operated pipet
US4498510A (en) * 1982-08-20 1985-02-12 Minshew Jr Edward C Device for drawing, holding and dispensing liquid
US4511534A (en) * 1982-05-26 1985-04-16 John T. Bennett Liquid transfer device
US4565100A (en) * 1981-10-02 1986-01-21 Culture-Tek Pipette device
US4801434A (en) * 1985-12-06 1989-01-31 Fuji Photo Film Co., Ltd. Dual pipette device
US4968148A (en) * 1984-03-01 1990-11-06 Molecular Devices Corporation Single source multi-site photometric measurement system
US5012682A (en) * 1988-10-21 1991-05-07 Firma Eppendorf-Netheler-Hinz Gmbh Pipetting device
US5021217A (en) * 1988-12-20 1991-06-04 Nichiryo Co., Ltd. Multipipet
US5112134A (en) * 1984-03-01 1992-05-12 Molecular Devices Corporation Single source multi-site photometric measurement system
US5540889A (en) * 1994-05-11 1996-07-30 Whitehead Institute For Biomedical Research Apparatus and method for a highly parallel pipetter
FR2755627A1 (fr) * 1996-11-13 1998-05-15 Labsystems Oy Pipette multi-cylindre
WO2000072971A1 (fr) * 1999-05-31 2000-12-07 Bridgestone Corporation Dispositif de pipettes
USH1960H1 (en) * 1995-04-10 2001-06-05 Alpha Therapeutic Corp. Automated method and system for testing blood samples
EP1136127A2 (de) * 2000-03-20 2001-09-26 Brand Gmbh + Co Kg Mehrkanal-Pipettiereinrichtung sowie Pipettenschaft dafür
EP1230979A2 (en) * 2001-02-09 2002-08-14 Biohit Oy Pipette with adjustable volume
WO2004009238A1 (en) * 2002-07-23 2004-01-29 Protedyne Corporation Liquid handling tool having hollow plunger
WO2004041433A1 (en) * 2002-11-08 2004-05-21 Biohit Oyj Multichannel pipette
DE102004055562A1 (de) * 2004-11-18 2006-06-01 Eppendorf Ag Handhabbares Dosiersystem
US20060160073A1 (en) * 1995-04-10 2006-07-20 Peddada Lorraine B Efficient algorithm for PCR testing of blood samples
US20070161959A1 (en) * 2006-01-09 2007-07-12 Spitz Gregory A Syringe filling apparatus
US20080006100A1 (en) * 2006-07-07 2008-01-10 Eppendorf Ag Pipetting device
US20090104079A1 (en) * 2007-10-17 2009-04-23 Rainin Instrument, Llc Liquid end assembly for a handheld multichannel pipette with adjustable nozzle spacing
US20100252579A1 (en) * 2004-05-10 2010-10-07 Bernd Steinbrenner Device for receiving and dispensing liquids
DE102010041833A1 (de) 2010-09-30 2012-04-05 INSTITUT FüR MIKROTECHNIK MAINZ GMBH Mikrofluidikchip mit mehreren Zylinder-Kolben-Anordnungen
US20140199216A1 (en) * 2013-01-15 2014-07-17 Rainin Instrument, Llc Liquid end assembly for a multichannel air displacement pipette
US9259737B2 (en) 2011-05-20 2016-02-16 Perkinelmer Health Sciences, Inc. Lab members and liquid handling systems and methods including same
WO2016028598A1 (en) 2014-08-20 2016-02-25 R. J. Reynolds Tobacco Company Pipetting system
US9283557B2 (en) 2012-03-30 2016-03-15 Perkinelmer Health Sciences, Inc. Lab members and liquid handling systems and methods including same
US9579646B2 (en) 2014-07-24 2017-02-28 Accel Biotech, Inc. Dual tip array dispensing head
CN108187771A (zh) * 2018-01-08 2018-06-22 江苏师范大学 一种自动定量梯度加样多道移液器活塞组件
WO2019089536A1 (en) * 2017-10-30 2019-05-09 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Methods and systems comprising modified pipettes for transferring and preserving biomaterial
US20210316297A1 (en) * 2011-09-23 2021-10-14 Abbott Diagnostics Scarborough, Inc. System and apparatus for reactions
DE202022104955U1 (de) 2022-09-01 2022-09-15 Brand Gmbh + Co Kg Verdrängereinrichtung und Pipettiervorrichtung
DE102022122178A1 (de) 2022-09-01 2024-03-07 Brand Gmbh + Co Kg Verdrängereinrichtung und Pipettiervorrichtung

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JPS5267389A (en) * 1975-12-01 1977-06-03 Kuraray Co Method and apparatus for precise and separate taking of liquids of multi components system
JPS5835981Y2 (ja) * 1978-02-06 1983-08-13 三洋電機株式会社 冷蔵庫
FI57704C (fi) * 1979-03-23 1980-10-10 Suovaniemi Finnpipette Seriepipett
DE3037826C2 (de) * 1980-10-07 1985-06-05 Drägerwerk AG, 2400 Lübeck Probenahmeröhrchen mit Verschlußkappen
FR2525770A1 (fr) * 1982-04-23 1983-10-28 Issa Georges Appareil a canaux multiples pour le prelevement et/ou la distribution de liquides dans des microplaques permettant de travailler en conditions steriles
EP0114056B1 (de) * 1983-01-15 1987-11-19 Hoechst Aktiengesellschaft Probensammler
GB2161398A (en) * 1984-07-11 1986-01-15 Scient Supplies M B Pipette
FR2612639B1 (fr) * 1987-03-19 1990-05-11 Ysebaert Doseur de quantites liquides variables
GB2204950A (en) * 1987-05-14 1988-11-23 Histopath Limited Cytology sample chamber
DE4003591A1 (de) * 1990-02-07 1991-08-08 Joerg Spindler Mehrkanalpipette mit neigungsspiel an der hubplatte aufweisenden kolben
DE69312839T2 (de) * 1992-09-30 1998-01-22 Johnson & Johnson Clin Diag Ansaugpipetten
JP3473409B2 (ja) * 1998-06-11 2003-12-02 松下電器産業株式会社 分注装置

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US3498342A (en) * 1967-05-17 1970-03-03 Univ Of Queensland The Multiple droppers
US3718439A (en) * 1970-06-12 1973-02-27 Instrumentation Labor Inc Analytical apparatus

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US2670673A (en) * 1950-07-17 1954-03-02 Joyce A Gordon Fluid injecting device
CH443723A (de) * 1966-05-04 1967-09-15 Polymetron Ag Kolben für Kolbenbüretten mit genau bearbeiteten Zylindern
FR1490704A (fr) * 1966-06-23 1967-08-04 Dispositif pour le prélèvement et la dépose d'échantillons de liquides

Patent Citations (2)

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Publication number Priority date Publication date Assignee Title
US3498342A (en) * 1967-05-17 1970-03-03 Univ Of Queensland The Multiple droppers
US3718439A (en) * 1970-06-12 1973-02-27 Instrumentation Labor Inc Analytical apparatus

Cited By (73)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4058370A (en) * 1974-07-05 1977-11-15 Osmo Antero Suovaniemi Apparatus for accurate pipetting of small liquid volumes
US4020698A (en) * 1974-10-29 1977-05-03 Marteau D Autry Eric Pipette which may be calibrated
US4215092A (en) * 1976-04-08 1980-07-29 Osmo A. Suovaniemi Apparatus for liquid portioning and liquid transferring
US4054062A (en) * 1976-05-03 1977-10-18 Oxford Laboratories Inc. Hand-held micropipettor with improved accuracy of liquid volumes transferred
US4237095A (en) * 1978-04-25 1980-12-02 Kommandiittiyhtio Finnpipette Osmo A. Suovaniemi Tip vessel for use in connection with a dosage pipette
US4263257A (en) * 1978-09-08 1981-04-21 Metsaele Seppo Juhani Pipette
US4268481A (en) * 1979-03-23 1981-05-19 Kommandittiyhtio Finnpipette Osmo A. Suovaniemi Pipette
US4335621A (en) * 1979-08-31 1982-06-22 Kommandiittiyhtio Finnpipette Osmo A. Suovaniemi Pipette
US4565100A (en) * 1981-10-02 1986-01-21 Culture-Tek Pipette device
US4442722A (en) * 1982-02-23 1984-04-17 Beckman Instruments Inc. Plunger operated pipet
US4511534A (en) * 1982-05-26 1985-04-16 John T. Bennett Liquid transfer device
US4498510A (en) * 1982-08-20 1985-02-12 Minshew Jr Edward C Device for drawing, holding and dispensing liquid
US4968148A (en) * 1984-03-01 1990-11-06 Molecular Devices Corporation Single source multi-site photometric measurement system
US5112134A (en) * 1984-03-01 1992-05-12 Molecular Devices Corporation Single source multi-site photometric measurement system
US4801434A (en) * 1985-12-06 1989-01-31 Fuji Photo Film Co., Ltd. Dual pipette device
US5012682A (en) * 1988-10-21 1991-05-07 Firma Eppendorf-Netheler-Hinz Gmbh Pipetting device
US5021217A (en) * 1988-12-20 1991-06-04 Nichiryo Co., Ltd. Multipipet
US5540889A (en) * 1994-05-11 1996-07-30 Whitehead Institute For Biomedical Research Apparatus and method for a highly parallel pipetter
US8158341B2 (en) 1995-04-10 2012-04-17 Baxter International Inc. Efficient algorithm for PCR testing of blood samples
USH1960H1 (en) * 1995-04-10 2001-06-05 Alpha Therapeutic Corp. Automated method and system for testing blood samples
US20060160073A1 (en) * 1995-04-10 2006-07-20 Peddada Lorraine B Efficient algorithm for PCR testing of blood samples
DE19750145C2 (de) * 1996-11-13 2000-05-18 Labsystems Oy Mehrzylinderpipette
US5970806A (en) * 1996-11-13 1999-10-26 Labsystems Oy Multi-cylinder pipette
FR2755627A1 (fr) * 1996-11-13 1998-05-15 Labsystems Oy Pipette multi-cylindre
US6673318B1 (en) 1999-05-31 2004-01-06 Bridgestone Corporation Pipette
WO2000072971A1 (fr) * 1999-05-31 2000-12-07 Bridgestone Corporation Dispositif de pipettes
EP1136127A2 (de) * 2000-03-20 2001-09-26 Brand Gmbh + Co Kg Mehrkanal-Pipettiereinrichtung sowie Pipettenschaft dafür
DE10013511A1 (de) * 2000-03-20 2001-10-11 Brand Gmbh & Co Kg Mehrkanal-Pipettiereinrichtung sowie Pipettenschaft dafür
EP1136127A3 (de) * 2000-03-20 2003-06-25 Brand Gmbh + Co Kg Mehrkanal-Pipettiereinrichtung sowie Pipettenschaft dafür
US6627160B2 (en) 2000-03-20 2003-09-30 Brand Gmbh + Co. Kg Multiple channel pipetting device
EP1230979A2 (en) * 2001-02-09 2002-08-14 Biohit Oy Pipette with adjustable volume
EP1230979A3 (en) * 2001-02-09 2003-10-29 Biohit Oyj Pipette with adjustable volume
WO2004009238A1 (en) * 2002-07-23 2004-01-29 Protedyne Corporation Liquid handling tool having hollow plunger
US20040018119A1 (en) * 2002-07-23 2004-01-29 Peter Massaro Liquid handling tool having porous plunger
US7438857B2 (en) 2002-07-23 2008-10-21 Protedyne Corporation Liquid handling tool having porous plunger
US20060123929A1 (en) * 2002-11-08 2006-06-15 Osma Suovaniemi Multichannel pipette
KR100937762B1 (ko) * 2002-11-08 2010-01-20 바이오히트 오와이제이 다채널 피펫
WO2004041433A1 (en) * 2002-11-08 2004-05-21 Biohit Oyj Multichannel pipette
US8685342B2 (en) * 2004-05-10 2014-04-01 Bernd Steinbrenner Device for receiving and dispensing liquids
US20100252579A1 (en) * 2004-05-10 2010-10-07 Bernd Steinbrenner Device for receiving and dispensing liquids
DE102004055562B4 (de) * 2004-11-18 2006-09-28 Eppendorf Ag Handhabbares Dosiersystem
DE102004055562A1 (de) * 2004-11-18 2006-06-01 Eppendorf Ag Handhabbares Dosiersystem
US7571747B2 (en) * 2006-01-09 2009-08-11 Spitz Gregory A Syringe filling apparatus
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Also Published As

Publication number Publication date
JPS5235557B2 (nl) 1977-09-09
SE385663B (sv) 1976-07-19
DE2366404C2 (de) 1985-12-12
NL175143C (nl) 1984-10-01
CA952488A (en) 1974-08-06
GB1392792A (en) 1975-04-30
JPS4890292A (nl) 1973-11-24
NL8105249A (nl) 1982-03-01
DE2304473C2 (de) 1983-01-05
CH551217A (de) 1974-07-15
DE2366403A1 (nl) 1982-09-23
CH556194A (de) 1974-11-29
FR2171453A1 (nl) 1973-09-21
DE2366404A1 (nl) 1982-09-23
DE2366403C2 (de) 1985-12-12
FR2171453B1 (nl) 1977-02-04
GB1392791A (en) 1975-04-30
DE2304473A1 (de) 1973-08-16
NL175143B (nl) 1984-05-01
IT977765B (it) 1974-09-20
NL7301922A (nl) 1973-08-14
SE7508369L (sv) 1975-07-23

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