US3853012A - Pipettes - Google Patents
Pipettes Download PDFInfo
- Publication number
- US3853012A US3853012A US18602371A US3853012A US 3853012 A US3853012 A US 3853012A US 18602371 A US18602371 A US 18602371A US 3853012 A US3853012 A US 3853012A
- Authority
- US
- United States
- Prior art keywords
- tip
- permanent
- pipette
- disposable
- disposable tip
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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Images
Classifications
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- C—CHEMISTRY; METALLURGY
- C01—INORGANIC CHEMISTRY
- C01B—NON-METALLIC ELEMENTS; COMPOUNDS THEREOF; METALLOIDS OR COMPOUNDS THEREOF NOT COVERED BY SUBCLASS C01C
- C01B17/00—Sulfur; Compounds thereof
- C01B17/69—Sulfur trioxide; Sulfuric acid
- C01B17/90—Separation; Purification
- C01B17/907—Removal of arsenic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/150007—Details
- A61B5/150015—Source of blood
- A61B5/150022—Source of blood for capillary blood or interstitial fluid
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/150007—Details
- A61B5/150053—Details for enhanced collection of blood or interstitial fluid at the sample site, e.g. by applying compression, heat, vibration, ultrasound, suction or vacuum to tissue; for reduction of pain or discomfort; Skin piercing elements, e.g. blades, needles, lancets or canulas, with adjustable piercing speed
- A61B5/150061—Means for enhancing collection
- A61B5/150099—Means for enhancing collection by negative pressure, other than vacuum extraction into a syringe by pulling on the piston rod or into pre-evacuated tubes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/150007—Details
- A61B5/150206—Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
- A61B5/150213—Venting means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/150007—Details
- A61B5/150206—Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
- A61B5/150236—Pistons, i.e. cylindrical bodies that sit inside the syringe barrel, typically with an air tight seal, and slide in the barrel to create a vacuum or to expel blood
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/150007—Details
- A61B5/150206—Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
- A61B5/150244—Rods for actuating or driving the piston, i.e. the cylindrical body that sits inside the syringe barrel, typically with an air tight seal, and slides in the barrel to create a vacuum or to expel blood
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/150007—Details
- A61B5/150206—Construction or design features not otherwise provided for; manufacturing or production; packages; sterilisation of piercing element, piercing device or sampling device
- A61B5/150259—Improved gripping, e.g. with high friction pattern or projections on the housing surface or an ergonometric shape
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/150007—Details
- A61B5/150343—Collection vessels for collecting blood samples from the skin surface, e.g. test tubes, cuvettes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/34—Constructions for connecting the needle, e.g. to syringe nozzle or needle hub
- A61M5/344—Constructions for connecting the needle, e.g. to syringe nozzle or needle hub using additional parts, e.g. clamping rings or collets
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/02—Burettes; Pipettes
- B01L3/0275—Interchangeable or disposable dispensing tips
- B01L3/0279—Interchangeable or disposable dispensing tips co-operating with positive ejection means
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31525—Dosing
- A61M5/31531—Microsyringes, e.g. having piston bore diameter close or equal to needle shaft diameter
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/34—Constructions for connecting the needle, e.g. to syringe nozzle or needle hub
- A61M5/346—Constructions for connecting the needle, e.g. to syringe nozzle or needle hub friction fit
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/32—Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles
- A61M5/34—Constructions for connecting the needle, e.g. to syringe nozzle or needle hub
- A61M5/347—Constructions for connecting the needle, e.g. to syringe nozzle or needle hub rotatable, e.g. bayonet or screw
Definitions
- the conventional mouth pipette has been giving way to manual pipettes. While the mouth pipette has been entirely satisfactory in use, and indeed may be preferred by the skilled technician who can manipulate it quite well and can dispense fluids from it with great accuracy, it has several disadvantages when compared to manual pipettes, especially those adapted to use a disposable tip.
- the mouth pipette requires that the technician using it develop a certain facility for drawing a measured quantity of liquid into the pipette, and for dispensing exact amounts of liquid from the pipette.
- the technician using it develop a certain facility for drawing a measured quantity of liquid into the pipette, and for dispensing exact amounts of liquid from the pipette.
- a clean pipette must be used for each sample.
- a third disadvantage of mouth pipettes is that careless use may result in drawing samples of biological fluids, such as plasma or blood cells, into the mouth with consequent risk of infection by pathogenic organisms contained in such samples.
- the disposable tips that are used with manual pipettes are generally elongated cone shaped members formed of a suitable plastic material which can be wedge fitted onto the tapered end of the pipette proper.
- the pipette is pressed into the disposable tip with sufficient force to insure that the tip will be frictionally held in place as a liquid is drawn into and dispensed therefrom.
- the tip can be dislodged and discarded by removing it with one hand while the pipette is held with the other.
- de-tipping members can be supplied to wedge the disposable tip off the pipette as the pipette is moved into contact with the de-tipping member. Another de-tipping member permits the disposable tip to fit under a ledge whereupon an upward pull on the pipette dislodges the tip.
- a pipette having a tapered end over which a disposable tip is wedge fitted, and a sleeve member fitted over the pipette body and spring biased away from the tapered end of the pipette.
- the sleeve member is slideable towards a disposable tip placed on the end of the pipette so that it bears against and pushes the disposable tip off the pipette.
- FIG. 1 is a top plan view of the pipette
- FIG. 2 is a longitudinal cross-sectional view of the pipette taken along line 2-2 of FIG. 1.
- the peripheral surface of the distal end of tube 10 may be slightly tapered to facilitate it being wedged into a disposable pipette tip 40.
- a hollow finger grip member 12, shaped substantially as shown, is threaded internally at 13 so that grip member 12 can be threaded onto member 11.
- a pairof quad rings 14 are placed inside the end of grip member 12 and against the annular ring 15. Consequently, when members 11 and 12 are threaded together, quad rings 14 are secured in a groove formed by the end of member 11 and annular ring 15.
- Annular ring 15, which is a separate member, applies an axial force to the quad rings thereby maintaining an inward radial sealing force upon piston 21.
- the quad rings will serve as an air tight seal around the pipette piston aswill presently be seen.
- the other end of grip member 12 also is internally threaded at 16.
- a restraining nut 17 having an inwardly turned rim 19 is externally threaded for engagement. with the threaded section 16 of member 12.
- the plunger assembly 20 of the pipette comprises a piston 21 which is knurled at one end and press fitted into a finger actuated cap 22.
- the remote end of piston 21 extends through quad rings 14 at all times during its reciprocation to fill and discharge the pipette.-
- the quad rings snugly surround the piston so as to maintain an air tight seal.
- a decorative insert 23 may be provided to givean attractive appearance to the pipette, especially if it is a colored plastic insert.
- a compression spring 24 biases plunger assembly 20 to a position where the flange 25 of cap 22 abuts rim 19 of restraining unit 17.
- plunger assembly 20 If plunger assembly 20 is moved against the action of spring 24 its movement is ultimately arrested by the engagement of flange 25 with shoulder 26 formed on the inside of grip member 12. It should be clear that the capacity of the present pipette depends upon the distance travelled by the plunger assembly 20 between the positions determined by shoulder 26 and rim 19. It should also be clear that the position of rim 19 can be varied depending upon how far nut 17 is threaded into grip member 12. Consequently, by finely adjusting the position of nut 17 the capacity of the pipette can be set very accurately.
- a set screw 27 is provided to lock nut 17 in its adjusted position with respect to grip member 12.
- the disposable tip removing assembly comprises a sleeve member 30 that is fitted around the outside surface of members 11 and 12.
- One end of sleeve member 30 is internally threaded at 31 and an annular ring 32 is provided.
- a compression spring 33 loosely fitted over tubing 10 bears against ring 32 and urges sleeve member 30 into engagement with the underside of the transverse arms of grip member 12.
- the other end of spring 33 is restrained by a washer 34 and a C circlet 35 the latter of which is snapped into a groove 36 pear difficult to assemble the pipette clue to the rela-' tively complicated shapes of the various parts thereof.
- Tubing is first press fitted or brazed to member 11 after which quad rings 14 are placed within the elongated portion of finger grip member 12 and the latter screwed on to the reduced threaded portion of member 11.
- the parts thus assembled are then placed within sleeve member as far as they will go.
- compression spring 33 is slipped over tubing 10 and compressed by washer 34 as circlet is snapped into groove 36.
- the de-tipper member 37 is then slipped over tubing 10 and threaded into sleeve member 30.
- the plunger assembly is next formed by press fitting cap 22 onto piston 21.
- Compression spring 24 is slipped over piston 21, and the latter is inserted through quad rings 14. Now nut 17 is fitted over cap 22 and threaded into grip member 12.
- the distance nut 17 is threaded into member 12 depends on the desired capacity of the pipette which in turn depends on the stroke of piston 21. This, of course, is determined by the distance flange 25 moves between the variably position rim 19 of nut 17 and shoulder 26. Once rim 19 is at the desired location, set screw 27 is tightened to lock nut 17 in place.
- a filling piece could be provided to fit over piston 21 adjacent to flange 25 to shorten the distance travelled by the piston when cap 22 is depressed. Such a piece would .enable the volume capacity of the pipette to be readily varied. Either the filling piece could be positioned along piston 21 and locked in a desired position, as by a set screw, or pieces of various lengths could be used to give different piston strokes. In the event a fill- I ing piece is used to control the capacity of the pipette, nut 17'would be used to provide a fine adjustment to the volume capacity.
- the pipette can be grasped in the way most comfortable to the technician. Either, the pipette can be grasped by the technician making a fist around sleeve member 30 with either the thumb or the index finger placed on insert 23 of cap 22, or by holding the sleeve member between the index and middle fingers with the thumb convenient to cap 22. Of course, the technician may adapt any grip which is found to be comfortable or convenient.
- the pipette is then pressed into the open end of a disposable tip which is thus wedged and sealed to the end of the pipette. It will be noted that the maximum engagement force that can be exerted is that exerted by spring 33.
- the plunger assembly is then depressed until flange 25 strikes shoulder 26, this action expelling a volume of air from tube 10 equal to the cross sectional area of piston 21 multiplied by the distance travelled by the piston, i.e., the distance between shoulder 26 and rim 19 less the thickness of flange 25.
- the quad rings 14 insure that all of the air is expelled from tube 10 and that none of it escapes along piston 21.
- the disposable tip 40 is then inserted into the liquid'being pipetted and plunger assembly 20 is released prior to removing the pipette from the liquid.
- Compression spring 24 moves assembly 20 to the position shown in the drawing, thus drawing a volume of liquid, essentially equal to the vol-' ume of air previously expelled, into disposable tip 40.
- a manual pipette adapted to have a disposable tip wedge fitted at one end thereof and in co-axial relationship thereto, the arrangement being such that a disposable tip is secured to the pipette only by the frictional force of the wedge fit, said pipette comprising a detipping member for removing a disposable tip that is wedge fitted to the pipette, said member being slideably mounted on said pipette in a direction parallel to the axis of the pipette and movable between a normal position away from a disposable tip and a position where it engages the end of a disposable tip and thereafter pushes the tip in an axial direction to free it from frictional engagement with the pipette.
- a manual pipette according to claim 1 including resilient means for biasing said de-tipping member to its normal position.
- sleeve member biasing spring means is a compression spring fitted over said tubular member, and including means secured to said tubular member for restraining one end of said compression spring while its remote end bears against said sleeve member and urges said sleeve member to its normal position.
- a manual pipette adapted to have a disposable tip wedge fitted at the end thereof, said pipette comprising a permanent tip member, a sleeve member within which said permanent tip memberslides and from which said permanent tip member projects, and spring means for biasing said permanent tip member to its projected position whereby when a disposable tip is being wedge fitted to said permanent tip member as by the pipette being held by said sleeve member and said permanent tip member pressed into engagement with a disposable tip, the force urging said permanent tip member into engagement with the disposable tip is determined by said spring means.
- a manual pipette according to claim 7 wherein said permanent tip member projects from said sleeve member by a predetermined distance so that when a disposable tip is being wedge fitted to said permanent tip member the end of said sleeve member will engage the end of the disposable tip and the force urging said permanent tip member into engagement with the disposable tip will be determined and limited by said spring means and its amount of compression.
- a pipette adapted to have a disposable tip mounted at one end thereof, said pipette comprising, a permanent tip member to which a disposable tip is frictionally joined so as to form an air-tight connection, and disposable tip removing means for removing a disposable tip from said permanent tip member, said permanent tip member and said disposable tip removing means being supported so as to enable relative movement therebetween as a result of which a disposable tip is disconnected from said permanent tip member.
- a pipette according to claim 9 wherein the disposable tip is a hollow conical element and said permanent tip member is adapted to fit within the disposable tip which is frictionally held thereon, and wherein the relative movement between said permanent tip member and said disposable tip removing means causes the latter to bear against the end of the disposable tip and thereby to push it off said permanent tip member.
- a pipette according to claim 10 including resilient means for biasing the end of said permanent tip member on which a disposable tip is held and the bearing end of said disposable tip removing means away from each other.
- a pipette according to claim 11 including a grip member means integrally connected with but spaced from said permanent tip member, and wherein said disposable tip removing means is a sleeve-like unit that encloses said permanent tip member but leaves the end thereof projecting from the sleeve-like unit, and wherein said disposable tip removing member is biased into abutting relationship with said grip member means by said resilient means.
- a pipette according to claim 10 including means to effect relative movement between said permanent tip member and said disposable tip removing means whereby a disposable tip is removed from said permanent tip member.
- a manual pipette comprising a permanent tip member adapted to have a disposable tip coupled thereto in an air-tight relationship, means for drawing a liquid into and for expelling it from a disposable tip coupled to said permanent tip member, and means independent of said last named means disposed adjacent said permanent tip member and in spaced relationship from the end thereof to which a disposable tip is coupled for dislodging a disposable tip from said permanent tip member when a relative sliding motion between said permanent tip member and said dislodging means is effected.
- a manual pipette according to claim 14 including spring means for biasing said permanent tip member and said disposable tip dislodging means to said spaced relationship.
- a manual pipette according to claim 15 including means for applying a force to overcome the force exerted by said spring means and thereby effect a relative movement between said permanent tip member and said disposable tip dislodging means.
- a manual pipette comprising a permanent tip member adapted to have a disposable tip frictionally connected to the outside surface of said member, a tip removing member adjacent the outside surface of said permanent tip member, and means supporting said members for relative movement therebetween whereby as a result of such movement a disposable tip is engaged by said tip removing member and freed from its frictional connection with said permanent tip member.
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Heart & Thoracic Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Hematology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Pathology (AREA)
- Molecular Biology (AREA)
- Surgery (AREA)
- Medical Informatics (AREA)
- Biophysics (AREA)
- Physics & Mathematics (AREA)
- Manufacturing & Machinery (AREA)
- Chemical & Material Sciences (AREA)
- Vascular Medicine (AREA)
- Anesthesiology (AREA)
- Dermatology (AREA)
- Organic Chemistry (AREA)
- Pain & Pain Management (AREA)
- Inorganic Chemistry (AREA)
- Clinical Laboratory Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Devices For Use In Laboratory Experiments (AREA)
- Sampling And Sample Adjustment (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
Priority Applications (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US05186023 US3853012A (en) | 1971-10-04 | 1971-10-04 | Pipettes |
IT53105/72A IT966141B (it) | 1971-10-04 | 1972-09-30 | Perfezionamento nelle pipette manua li |
CA153,208A CA976929A (en) | 1971-10-04 | 1972-10-04 | Self-detipping pipette |
GB4568572A GB1411424A (en) | 1971-10-04 | 1972-10-04 | Manual pipette |
JP9974972A JPS5628582B2 (it) | 1971-10-04 | 1972-10-04 | |
DE19727236386U DE7236386U (de) | 1971-10-04 | 1972-10-04 | Handpipetten |
FR7235142A FR2156019B1 (it) | 1971-10-04 | 1972-10-04 | |
DE2248573A DE2248573B2 (de) | 1971-10-04 | 1972-10-04 | Handpipette |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US05186023 US3853012A (en) | 1971-10-04 | 1971-10-04 | Pipettes |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US06/021,965 Reissue USRE30453E (en) | 1979-03-19 | 1979-03-19 | Pipettes |
Publications (1)
Publication Number | Publication Date |
---|---|
US3853012A true US3853012A (en) | 1974-12-10 |
Family
ID=52596253
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US05186023 Expired - Lifetime US3853012A (en) | 1971-10-04 | 1971-10-04 | Pipettes |
Country Status (7)
Country | Link |
---|---|
US (1) | US3853012A (it) |
JP (1) | JPS5628582B2 (it) |
CA (1) | CA976929A (it) |
DE (2) | DE7236386U (it) |
FR (1) | FR2156019B1 (it) |
GB (1) | GB1411424A (it) |
IT (1) | IT966141B (it) |
Cited By (28)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3918308A (en) * | 1973-04-16 | 1975-11-11 | Oxford Lab | Liquid transfer pipetting device with a tip ejector |
US3991617A (en) * | 1974-10-15 | 1976-11-16 | Marteau D Autry Eric J H | Device for ejecting the removable tip of a pipette |
US4009611A (en) * | 1976-05-13 | 1977-03-01 | Oxford Laboratories Inc. | Hand-held micropipettor with improved pipette tip ejector |
US4041764A (en) * | 1975-11-05 | 1977-08-16 | Eppendorf Geratebau Netheler & Hinz Gmbh | Pipette device |
US4187724A (en) * | 1978-01-11 | 1980-02-12 | Indicon Inc. | Replaceable tip for a pipette |
WO1981001666A1 (en) * | 1979-12-10 | 1981-06-25 | Indicon Inc | Replaceable tip for a pipette |
US4343418A (en) * | 1980-06-05 | 1982-08-10 | Pennwalt Corporation | Dispenser for dental sealant |
US4369665A (en) * | 1978-01-11 | 1983-01-25 | Indicon Inc. | Manually holdable automatic pipette |
US4399712A (en) * | 1981-02-09 | 1983-08-23 | Nichiryo Co., Ltd. | Semi-automatic electro-mechanical pipette with controlled tip remover |
US4442722A (en) * | 1982-02-23 | 1984-04-17 | Beckman Instruments Inc. | Plunger operated pipet |
US4672857A (en) * | 1985-09-10 | 1987-06-16 | Labindustries, Inc. | Liquid microdispenser |
US4821586A (en) * | 1988-02-25 | 1989-04-18 | Medical Laboratory Automation, Inc. | Programmable pipette |
US5090255A (en) * | 1990-03-27 | 1992-02-25 | Drummond Scientific Company | Programmable pipet apparatus |
US5104624A (en) * | 1989-10-20 | 1992-04-14 | Costar Corporation | Pipetter |
US5511433A (en) * | 1990-05-04 | 1996-04-30 | Eppendorf-Netherler-Hinz Gmbh | Pipette device |
WO1999064159A1 (en) * | 1998-06-10 | 1999-12-16 | Biohit Oyj | Suction device with means for removing a replaceable tip |
EP1272825A1 (en) * | 2000-02-03 | 2003-01-08 | Rainin Instrument LLC. | Pipette device with tip ejector utilizing stored energy |
US20030099578A1 (en) * | 2001-10-16 | 2003-05-29 | Richard Cote | Hand-held pipettor |
US6601433B2 (en) | 2000-06-26 | 2003-08-05 | Vistalab Technologies, Inc. | Hand-held pipette |
US20040094638A1 (en) * | 2000-06-26 | 2004-05-20 | Cronenberg Richard A. | Automatic pipette identification |
US20050142038A1 (en) * | 2003-12-31 | 2005-06-30 | Rainin Instrument, Llc | Volume adjustable manual pipette with quick set volume adjustment |
US20050262951A1 (en) * | 2004-05-27 | 2005-12-01 | Richard Cote | Hand held pipette |
US20060027033A1 (en) * | 2002-10-16 | 2006-02-09 | Richard Cote | Hand-held pipette employing voice recognition control |
US20060123929A1 (en) * | 2002-11-08 | 2006-06-15 | Osma Suovaniemi | Multichannel pipette |
US7416704B2 (en) | 2000-06-26 | 2008-08-26 | Vistalab Technologies, Inc. | Handheld pipette |
USD620602S1 (en) | 2008-01-03 | 2010-07-27 | Vistalab Technologies, Inc. | Pipette |
US8899118B1 (en) | 2009-05-11 | 2014-12-02 | Dan Seguin | Multi-channel aspirating and dispensing instrument |
US10809275B2 (en) | 2016-06-24 | 2020-10-20 | Kobra Biosolutions, Llc | Verification pipette and vision apparatus |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2225211B1 (it) * | 1973-04-16 | 1979-02-16 | Oxford Lab | |
FR2295405A1 (fr) * | 1974-10-29 | 1976-07-16 | Marteau D Autry Eric | Pipette etalonnable |
US4050316A (en) * | 1975-11-03 | 1977-09-27 | Becton, Dickinson And Company | Pipette aspirator device |
DE102016121813A1 (de) * | 2016-11-14 | 2018-05-17 | Ika-Werke Gmbh & Co. Kg | Pipette und Verfahren zum Einstellen eines zu pipettierenden Volumens einer Pipette |
CN112517098B (zh) * | 2020-12-01 | 2022-05-03 | 重庆市开州区华兰生物单采血浆有限公司 | 一种生物医学实验室用延时补压移液器 |
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US2724275A (en) * | 1952-03-21 | 1955-11-22 | Persson Gustav Folke | Laboratory pump for drawing up fluids in a pipette |
US2875760A (en) * | 1954-09-11 | 1959-03-03 | Haber Christian | Injection equipment |
US3525264A (en) * | 1968-04-05 | 1970-08-25 | Becton Dickinson Co | Micropipette holder |
US3766785A (en) * | 1971-05-17 | 1973-10-23 | Analytical Prod | Automatic pipette |
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US2530909A (en) * | 1947-11-14 | 1950-11-21 | Carl A Nisson | Mechanical pipette |
DE883053C (de) * | 1951-10-09 | 1953-07-13 | Emanuel Alder | Kanuelenauswerfer fuer Injektionsspritze |
DE1291142B (de) * | 1964-04-25 | 1969-03-20 | Eppendorf Geraetebau Netheler | Vorrichtung zum exakten Abmessen und UEbertragen kleiner Fluessigkeitsmengen |
-
1971
- 1971-10-04 US US05186023 patent/US3853012A/en not_active Expired - Lifetime
-
1972
- 1972-09-30 IT IT53105/72A patent/IT966141B/it active
- 1972-10-04 GB GB4568572A patent/GB1411424A/en not_active Expired
- 1972-10-04 DE DE19727236386U patent/DE7236386U/de not_active Expired
- 1972-10-04 DE DE2248573A patent/DE2248573B2/de not_active Withdrawn
- 1972-10-04 CA CA153,208A patent/CA976929A/en not_active Expired
- 1972-10-04 FR FR7235142A patent/FR2156019B1/fr not_active Expired
- 1972-10-04 JP JP9974972A patent/JPS5628582B2/ja not_active Expired
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US2724275A (en) * | 1952-03-21 | 1955-11-22 | Persson Gustav Folke | Laboratory pump for drawing up fluids in a pipette |
US2875760A (en) * | 1954-09-11 | 1959-03-03 | Haber Christian | Injection equipment |
US3525264A (en) * | 1968-04-05 | 1970-08-25 | Becton Dickinson Co | Micropipette holder |
US3766785A (en) * | 1971-05-17 | 1973-10-23 | Analytical Prod | Automatic pipette |
Cited By (40)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3918308A (en) * | 1973-04-16 | 1975-11-11 | Oxford Lab | Liquid transfer pipetting device with a tip ejector |
US3991617A (en) * | 1974-10-15 | 1976-11-16 | Marteau D Autry Eric J H | Device for ejecting the removable tip of a pipette |
USRE32210E (en) * | 1974-10-15 | 1986-07-22 | Device for ejecting the removable tip of a pipette | |
US4041764A (en) * | 1975-11-05 | 1977-08-16 | Eppendorf Geratebau Netheler & Hinz Gmbh | Pipette device |
US4009611A (en) * | 1976-05-13 | 1977-03-01 | Oxford Laboratories Inc. | Hand-held micropipettor with improved pipette tip ejector |
US4187724A (en) * | 1978-01-11 | 1980-02-12 | Indicon Inc. | Replaceable tip for a pipette |
US4369665A (en) * | 1978-01-11 | 1983-01-25 | Indicon Inc. | Manually holdable automatic pipette |
WO1981001666A1 (en) * | 1979-12-10 | 1981-06-25 | Indicon Inc | Replaceable tip for a pipette |
US4343418A (en) * | 1980-06-05 | 1982-08-10 | Pennwalt Corporation | Dispenser for dental sealant |
US4399712A (en) * | 1981-02-09 | 1983-08-23 | Nichiryo Co., Ltd. | Semi-automatic electro-mechanical pipette with controlled tip remover |
US4442722A (en) * | 1982-02-23 | 1984-04-17 | Beckman Instruments Inc. | Plunger operated pipet |
US4672857A (en) * | 1985-09-10 | 1987-06-16 | Labindustries, Inc. | Liquid microdispenser |
US4821586A (en) * | 1988-02-25 | 1989-04-18 | Medical Laboratory Automation, Inc. | Programmable pipette |
US5104624A (en) * | 1989-10-20 | 1992-04-14 | Costar Corporation | Pipetter |
US5090255A (en) * | 1990-03-27 | 1992-02-25 | Drummond Scientific Company | Programmable pipet apparatus |
US5511433A (en) * | 1990-05-04 | 1996-04-30 | Eppendorf-Netherler-Hinz Gmbh | Pipette device |
WO1999064159A1 (en) * | 1998-06-10 | 1999-12-16 | Biohit Oyj | Suction device with means for removing a replaceable tip |
US6324925B1 (en) | 1998-06-10 | 2001-12-04 | Biohit Oyj | Suction device with means for removing a replaceable tip |
EP1272825A4 (en) * | 2000-02-03 | 2003-02-26 | Rainin Instr Llc | PIPETTE DEVICE WITH TIP INJECTOR USING STORED ENERGY |
EP1272825A1 (en) * | 2000-02-03 | 2003-01-08 | Rainin Instrument LLC. | Pipette device with tip ejector utilizing stored energy |
US6977062B2 (en) | 2000-06-26 | 2005-12-20 | Vistalab Technologies, Inc. | Automatic pipette identification |
US6601433B2 (en) | 2000-06-26 | 2003-08-05 | Vistalab Technologies, Inc. | Hand-held pipette |
US20040094638A1 (en) * | 2000-06-26 | 2004-05-20 | Cronenberg Richard A. | Automatic pipette identification |
US6749812B2 (en) | 2000-06-26 | 2004-06-15 | Vistalab Technologies | Automatic pipette detipping |
US8114362B2 (en) | 2000-06-26 | 2012-02-14 | Vistalab Technologies, Inc. | Automatic pipette identification |
US7416704B2 (en) | 2000-06-26 | 2008-08-26 | Vistalab Technologies, Inc. | Handheld pipette |
US20030099578A1 (en) * | 2001-10-16 | 2003-05-29 | Richard Cote | Hand-held pipettor |
US8088342B2 (en) | 2001-10-16 | 2012-01-03 | Matrix Technologies Corporation | Hand-held pipettor |
US6923938B2 (en) | 2001-10-16 | 2005-08-02 | Matrix Technologies Corporation | Hand-held pipettor |
US20060027033A1 (en) * | 2002-10-16 | 2006-02-09 | Richard Cote | Hand-held pipette employing voice recognition control |
US20060123929A1 (en) * | 2002-11-08 | 2006-06-15 | Osma Suovaniemi | Multichannel pipette |
US7175813B2 (en) * | 2003-12-31 | 2007-02-13 | Rainin Instrument, Llc | Volume adjustable manual pipette with quick set volume adjustment |
WO2005065360A3 (en) * | 2003-12-31 | 2005-11-03 | Rainin Instr Llc | Volume adjustable manual pipette with quick set volume adjustment |
CN100450626C (zh) * | 2003-12-31 | 2009-01-14 | 瑞宁器材公司 | 具有快速设定容积调整的可调整容积的手动式吸量管 |
US20050142038A1 (en) * | 2003-12-31 | 2005-06-30 | Rainin Instrument, Llc | Volume adjustable manual pipette with quick set volume adjustment |
US7284454B2 (en) | 2004-05-27 | 2007-10-23 | Matrix Technologies Corporation | Hand held pipette |
US20050262951A1 (en) * | 2004-05-27 | 2005-12-01 | Richard Cote | Hand held pipette |
USD620602S1 (en) | 2008-01-03 | 2010-07-27 | Vistalab Technologies, Inc. | Pipette |
US8899118B1 (en) | 2009-05-11 | 2014-12-02 | Dan Seguin | Multi-channel aspirating and dispensing instrument |
US10809275B2 (en) | 2016-06-24 | 2020-10-20 | Kobra Biosolutions, Llc | Verification pipette and vision apparatus |
Also Published As
Publication number | Publication date |
---|---|
GB1411424A (en) | 1975-10-22 |
DE2248573B2 (de) | 1979-03-29 |
JPS4846390A (it) | 1973-07-02 |
JPS5628582B2 (it) | 1981-07-02 |
IT966141B (it) | 1974-02-11 |
CA976929A (en) | 1975-10-28 |
DE7236386U (de) | 1977-12-08 |
FR2156019B1 (it) | 1977-07-29 |
DE2248573A1 (de) | 1973-04-12 |
FR2156019A1 (it) | 1973-05-25 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
AS | Assignment |
Owner name: MLA SYSTEMS, INC., NEW YORK Free format text: ASSIGNMENT OF ASSIGNORS INTEREST;ASSIGNOR:MEDICAL LABORATORY AUTOMATION, INC.;REEL/FRAME:009507/0691 Effective date: 19980728 |