US3552212A - Device for cleaning the exterior of an elongated body - Google Patents

Device for cleaning the exterior of an elongated body Download PDF

Info

Publication number
US3552212A
US3552212A US780787A US3552212DA US3552212A US 3552212 A US3552212 A US 3552212A US 780787 A US780787 A US 780787A US 3552212D A US3552212D A US 3552212DA US 3552212 A US3552212 A US 3552212A
Authority
US
United States
Prior art keywords
tube
sample
bore
take
probe
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
US780787A
Other languages
English (en)
Inventor
Erik Lars Ohlin
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Application granted granted Critical
Publication of US3552212A publication Critical patent/US3552212A/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Images

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1004—Cleaning sample transfer devices

Definitions

  • ABSTRACT .OF- THE DISCLOSURE A device for cleaning the outer surface of a take-01f tube in aliqu'id analysis apparatus or other elongated bodies of uniform cross-section.
  • a collar having a bore Slightly larger in diameter than the take-off tube is positioned so that the' portion of the take-01f tube to be cleaned passes through the bore when it is moved up and down to aspirate samples.
  • This invention relates to a device for cleaning the exterior of an elongated body, and more particularly to a device for removing loosely adhering matter, such as liquid droplets, from the exterior of an elongated member of substantially uniform cross-section, such as a tube or a 3,552,212 Patented Jan. 5, 1971 ferred embodiment of the cleaning device according to the invention.
  • FIG. 2 is a View similar to FIG. 1 and showing the cleaning device in operation.
  • FIG. 3 is an enlarged sectional view illustrating the operation of the cleaning device.
  • the liquid-sample analysis apparatus shown therein comprises a housing 11 providing a support surface 12 for first and second elongated sample carriers 13 and 14.
  • Each sample carrier holds a series of sample tubes 15 and 16, only one sample tube being shown for each carrier.
  • a measured quantity of the liquid sample in each sample tube 15 of the first sample carrier 13 is to be transferred to a corresponding sample tube 16 of the second sample carrier. 14 and mixed therein with a diluent or other conditioning liquid.
  • a transfer device 17 which comprises a take-off probe 18 having a tubular lower portion 19 of uniform cross-section and an bulbuous upper portion 20 connected to a suction source and a supply of conditioning liquid (not shown) through rodQ'Ihe r invention is particularly, although not exclusively,-applicable to apparatus for automatic sequential processing'or analysis of a'series of liquidsamples, and for convenience it'will'b described wtih reference to such application.
  • Many types of automated apparatus for sequential processingor analysis of aseries of liquid samples supplied in succession from separate containers require that the samples be aspirated from their respective containers as a step of the processing or'analysis procedure.
  • the take-01f probe 18 is supported by an arm 22 which is rigidly secured to a post 23 on the housing 11.
  • the post 23 is mounted for axial reciprocation and rotation by a mechanism not shown.
  • the two sample carriers 13 and 14 are advanced step by step and in synchronism with each other along the support surface 12 in a direction perpendicular to the plane of the drawing to sequentially position the sample tubes 15 and 16 in a take-01f position in vertical register with the take-01f probe 18 as shown and a sample receiving position respectively.
  • the post 23 is displaced downwardly from the position shown in FIG. 1 to insert the open lower end of the probe 18 into the sample in the sample tube 15 being in the take-01f position.
  • Suction is applied to the conduit 21 to cause the probe to aspirate a measured quantity of the sample, and the post 23 is then displaced upwardly to withdraw the probe (FIG.
  • the inner surface of the tubular probe may be freed for sample residues by passing a wash-liquid through the lumen of the probe, but efficient cleaning of the outer surface often presents a problem, even if the probe is made of a hydrophobic material.
  • a more particular object of the present invention is to provide a device which is capable of efiecting an efficient removal of sample residues from the outer surface of a tubular probe of a liquidsample take-01f device.
  • the tube 16 being in the receiving position (in the position shown in FIG. 1 the arm 22 is at an angle to the plane of the drawing).
  • the quantity of sample held in the probe 18 is ejected to the sample tube 16 and a measured quantity of conditioning liquid is supplied through the conduit 21 to condition the sample and wash out any sample residues. from the interior of the probe.
  • a measured quantity of conditioning liquid is supplied through the conduit 21 to condition the sample and wash out any sample residues. from the interior of the probe.
  • droplets of the sample liquid may remain on the outer surface of the probe portion 19 as indicated in FIGS. 2 and 3, even if the probe is made of a hydrophobic material.
  • the cleaning device 24 comprises a collar 25 secured to the housing 11 between the probe 18 and the sample carrier 13 and having a vertical bore 26 therethrough which is in vertical register with the probe portion 19 source (not shown) is connected to an intermediate enlarged portion 28 of the bore 26 through a conduit 29 and a passage 30 in the collar.
  • the upper end of the bore 26 is in open communication with a recess 31 provided in the upper portion of the collar 25.
  • a suitable wash-liquid 32 may be continuously or intermittently supplied to the recess 31 through a conduit 33 and a passage 34 in the collar.
  • the operation of the cleaning device 24 is as follows:
  • the wash-liquid may be dispensed with so that air is drawn through both ends of the annular space 27 during the downward as Well as the upward movement of the probe 18.
  • the supply of wash-liquid is preferred, since it ensures a more efficient cleaning.
  • the shape of the bore 26 and the relative dimensions of the bore 26 and the probe portion 19 to be cleaned are not very critical, but it will be understood that if the diameter of the bore is too large in relation to the diameter of the probe portion, the flow of wash-liquid and air may be inadequate to ensure an efiicient removal of the sample residues, and if the diameter is too small, the sample residues may be wiped off by the lower peripheral edge of the bore and accumulate on the lower surface of the collar 25. Naturally, the suction applied to the bore has to be adequate to ensure that no wash-liquid drops from the bore 26 into the sample tubes 15 or to the support surface 12.
  • a device for cleaning an elongated, vertically mounted member of substantially uniform cross-section comprising a collar having a bore therethrough and adapted to encircle an axial portion of said member in radially spaced relation to define between the walls of said bore and said member an annular space, means for relatively displacing said collar and said member axially over a length of the latter to be cleaned while retaining said length and collar in radially spaced relation, and suction conduit means connected to said bore between the ends thereof to provide a fluid passageway around said portion of said member through said space to said suction conduit means, said annular space being sufiiciently small so that air drawn therethrough by the reduced pressure from said suction conduit means will entrain any loosely adhering matter on the exterior of said length of said member and being sufliciently large to prevent wiping of such loosely adhering matter from the exterior of said member.
  • a device including means for supplying wash-liquid to said space.
  • a device according to claim 1 wherein said collar is provided with a recess communicating with the upper end of said bore and means are provided for supplying wash-liquid to said recess.
  • a stationary collar having a bore therethrough and adapted to encircle an axial portion of said probe in radially spaced relation to define between the walls of said bore and said portion an annular space, means for displacing said probe through.

Landscapes

  • Physics & Mathematics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Automatic Analysis And Handling Materials Therefor (AREA)
US780787A 1967-12-06 1968-12-03 Device for cleaning the exterior of an elongated body Expired - Lifetime US3552212A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE16779/67A SE336241B (en, 2012) 1967-12-06 1967-12-06

Publications (1)

Publication Number Publication Date
US3552212A true US3552212A (en) 1971-01-05

Family

ID=20302736

Family Applications (1)

Application Number Title Priority Date Filing Date
US780787A Expired - Lifetime US3552212A (en) 1967-12-06 1968-12-03 Device for cleaning the exterior of an elongated body

Country Status (3)

Country Link
US (1) US3552212A (en, 2012)
GB (1) GB1213421A (en, 2012)
SE (1) SE336241B (en, 2012)

Cited By (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3682185A (en) * 1970-03-10 1972-08-08 James J Murray Plated wire manufacturing cell
US3719086A (en) * 1971-01-12 1973-03-06 Damon Corp Liquids sampler with probe-bathing chamber
US3748911A (en) * 1970-12-29 1973-07-31 Hoffmann La Roche Device for taking samples of liquid specimens especially for the automatic analysis apparatus
US3948605A (en) * 1974-08-22 1976-04-06 The Perkin-Elmer Corporation Diluter for a kinetic analysis apparatus
US3993293A (en) * 1974-06-25 1976-11-23 Mitsui Mining & Smelting Co., Ltd. Automatic leaching system for hydro-metallurgical production of zinc
US3999949A (en) * 1974-01-16 1976-12-28 Duni-Bila Ab Product for use in chemical working operations
US4044616A (en) * 1975-10-01 1977-08-30 Harris Sr Rano J Automatic fluid injector
US4046225A (en) * 1975-08-11 1977-09-06 Bell Telephone Laboratories, Incorporated Cable lubrication method
US4076503A (en) * 1974-08-22 1978-02-28 The Perkin-Elmer Corporation Pipetting system for use in kinetic analysis apparatus and the like
US4094196A (en) * 1977-02-25 1978-06-13 Waters Associates, Inc. Sample injection with automatic cleaning of sampling conduit
FR2401412A1 (fr) * 1977-02-25 1979-03-23 Waters Associates Inc Appareil injecteur d'echantillons dans un appareil d'analyse et son dispositif d'etancheite
US4217780A (en) * 1979-07-09 1980-08-19 Ortho Diagnostic, Inc. Automated, self-cleaning fluid sampling apparatus
US4297903A (en) * 1980-04-24 1981-11-03 Beckman Instruments, Inc. Liquid transfer valve
FR2482310A1 (fr) * 1980-05-09 1981-11-13 Prioux Alain Dispositif de transfert de liquide pour un appareil de prelevement ou de fourniture d'echantillons liquides
US4441374A (en) * 1979-10-17 1984-04-10 Olympus Optical Co. Ltd. Device for diluting liquid sample
US4463615A (en) * 1980-04-24 1984-08-07 Beckman Instruments, Inc. Liquid transfer valve
EP0103268A3 (en) * 1982-09-13 1985-05-15 Hitachi, Ltd. Sampling apparatus
US4615360A (en) * 1985-09-05 1986-10-07 Eastman Kodak Company Means providing separation of exterior sheath of liquid on dispensing tip
US4817443A (en) * 1986-11-14 1989-04-04 A.B.X. Device for cleaning a liquid sample taking needle
US4820497A (en) * 1986-06-23 1989-04-11 E. I. Du Pont De Nemours And Company Movable cleaning assembly for an aspirating needle
US4933997A (en) * 1985-03-07 1990-06-19 Aisin Seiki Kabushiki Kaisha Method of driving private parts washing device
EP0661542A3 (en) * 1993-12-20 1996-04-24 Toa Medical Electronics Pipette cleaning unit.
US5827744A (en) * 1995-11-06 1998-10-27 Dade International Inc. Method and apparatus for cleaning a liquid dispensing probe
US6044618A (en) * 1994-12-23 2000-04-04 Instruments De Medecine Veterinaire Machine for making up ready to use doses of animal semen and dose of semen made up by this machine
WO2000051737A1 (en) * 1999-03-05 2000-09-08 Hitachi Chemical Co., Ltd. Self-washable nozzle tip
DE10001895A1 (de) * 2000-01-19 2001-07-26 Mettler Toledo Gmbh Analysenvorrichtung und Antriebsvorrichtung hierfür
WO2004063754A1 (en) * 2003-01-13 2004-07-29 Pfizer Products Inc. System for rinsing a sample probe comprising a probe guide support
US20050074363A1 (en) * 2003-07-18 2005-04-07 Dunfee William David Liquid sampling probe and cleaning fluidics system
US20050281713A1 (en) * 2004-06-18 2005-12-22 Bioanalytical Systems, Inc. (An Indiana Company) System and method for sample collection
US20060266766A1 (en) * 2005-05-26 2006-11-30 Peter Andrews Fluid-dispensing apparatus with controlled tear-off and methods of using the same
US20070095159A1 (en) * 2003-07-18 2007-05-03 C2 Diagnostics Sampling device and method for an automatic analyser
US20070204571A1 (en) * 2004-04-09 2007-09-06 Nestec S.A. Process for preparing, prior to filling, a wafer cornet, cornet thus obtained and installation for implementing the process
WO2014112591A1 (ja) * 2013-01-21 2014-07-24 株式会社日立ハイテクノロジーズ 自動分析装置
US20140290341A1 (en) * 2011-08-03 2014-10-02 Becton, Dickinson And Company Detection of a Compromised Flow Line in a Laboratory Instrument
CN105327907A (zh) * 2015-12-14 2016-02-17 重庆南方数控设备有限责任公司 一种用于清洗采样针的涡流式洗针装置
CN105917238A (zh) * 2014-01-24 2016-08-31 株式会社日立高新技术 自动分析装置
CN108856181A (zh) * 2018-04-28 2018-11-23 深圳市亚辉龙生物科技股份有限公司 磁分离用吸液针清洁方法及应用该方法的清洗设备
CN110877040A (zh) * 2019-11-20 2020-03-13 香港大德昌龙生物科技有限公司 加样针清洗设备及加样针清洗的方法、应用
US11156628B2 (en) * 2017-02-24 2021-10-26 Hitachi High-Tech Corporation Automatic analyzer

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102520118A (zh) * 2011-11-23 2012-06-27 宁波市牛奶集团有限公司 一种滴定系统

Cited By (56)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3682185A (en) * 1970-03-10 1972-08-08 James J Murray Plated wire manufacturing cell
US3748911A (en) * 1970-12-29 1973-07-31 Hoffmann La Roche Device for taking samples of liquid specimens especially for the automatic analysis apparatus
US3719086A (en) * 1971-01-12 1973-03-06 Damon Corp Liquids sampler with probe-bathing chamber
US3999949A (en) * 1974-01-16 1976-12-28 Duni-Bila Ab Product for use in chemical working operations
US3993293A (en) * 1974-06-25 1976-11-23 Mitsui Mining & Smelting Co., Ltd. Automatic leaching system for hydro-metallurgical production of zinc
US3948605A (en) * 1974-08-22 1976-04-06 The Perkin-Elmer Corporation Diluter for a kinetic analysis apparatus
US4076503A (en) * 1974-08-22 1978-02-28 The Perkin-Elmer Corporation Pipetting system for use in kinetic analysis apparatus and the like
US4046225A (en) * 1975-08-11 1977-09-06 Bell Telephone Laboratories, Incorporated Cable lubrication method
US4044616A (en) * 1975-10-01 1977-08-30 Harris Sr Rano J Automatic fluid injector
FR2401412A1 (fr) * 1977-02-25 1979-03-23 Waters Associates Inc Appareil injecteur d'echantillons dans un appareil d'analyse et son dispositif d'etancheite
DE2858100C2 (de) * 1977-02-25 1985-09-19 Waters Associates, Inc., Milford, Mass. Vorrichtung zum Säubern einer Probenleitung
DE2807291A1 (de) * 1977-02-25 1978-11-30 Waters Associates Inc Vorrichtung zum einspritzen einer fluessigkeitsprobe
US4094196A (en) * 1977-02-25 1978-06-13 Waters Associates, Inc. Sample injection with automatic cleaning of sampling conduit
FR2382004A1 (fr) * 1977-02-25 1978-09-22 Waters Associates Inc Appareil et procede d'injection d'echantillons dans un appareil d'analyse, dispositif et procede de lavage de son conduit d'injection
US4217780A (en) * 1979-07-09 1980-08-19 Ortho Diagnostic, Inc. Automated, self-cleaning fluid sampling apparatus
US4441374A (en) * 1979-10-17 1984-04-10 Olympus Optical Co. Ltd. Device for diluting liquid sample
US4297903A (en) * 1980-04-24 1981-11-03 Beckman Instruments, Inc. Liquid transfer valve
US4463615A (en) * 1980-04-24 1984-08-07 Beckman Instruments, Inc. Liquid transfer valve
FR2482310A1 (fr) * 1980-05-09 1981-11-13 Prioux Alain Dispositif de transfert de liquide pour un appareil de prelevement ou de fourniture d'echantillons liquides
EP0103268A3 (en) * 1982-09-13 1985-05-15 Hitachi, Ltd. Sampling apparatus
US4933997A (en) * 1985-03-07 1990-06-19 Aisin Seiki Kabushiki Kaisha Method of driving private parts washing device
US4615360A (en) * 1985-09-05 1986-10-07 Eastman Kodak Company Means providing separation of exterior sheath of liquid on dispensing tip
US4820497A (en) * 1986-06-23 1989-04-11 E. I. Du Pont De Nemours And Company Movable cleaning assembly for an aspirating needle
US4817443A (en) * 1986-11-14 1989-04-04 A.B.X. Device for cleaning a liquid sample taking needle
EP0661542A3 (en) * 1993-12-20 1996-04-24 Toa Medical Electronics Pipette cleaning unit.
US5592959A (en) * 1993-12-20 1997-01-14 Toa Medical Electronics Co., Ltd. Pipet washing apparatus
US6079184A (en) * 1994-12-23 2000-06-27 Instruments De Medecine Veterinaire Machine for making up ready to use doses of animal semen and dose of semen made up by this machine
US6044618A (en) * 1994-12-23 2000-04-04 Instruments De Medecine Veterinaire Machine for making up ready to use doses of animal semen and dose of semen made up by this machine
US5827744A (en) * 1995-11-06 1998-10-27 Dade International Inc. Method and apparatus for cleaning a liquid dispensing probe
WO2000051737A1 (en) * 1999-03-05 2000-09-08 Hitachi Chemical Co., Ltd. Self-washable nozzle tip
DE10001895A1 (de) * 2000-01-19 2001-07-26 Mettler Toledo Gmbh Analysenvorrichtung und Antriebsvorrichtung hierfür
US7862774B2 (en) 2000-01-19 2011-01-04 Mettler-Toledo Ag Analyzer system and drive mechanism for same
WO2004063754A1 (en) * 2003-01-13 2004-07-29 Pfizer Products Inc. System for rinsing a sample probe comprising a probe guide support
US20040194562A1 (en) * 2003-01-13 2004-10-07 Pfizer Inc. Sample probe guide support
US20050074363A1 (en) * 2003-07-18 2005-04-07 Dunfee William David Liquid sampling probe and cleaning fluidics system
US7186378B2 (en) 2003-07-18 2007-03-06 Dade Behring Inc. Liquid sampling probe and cleaning fluidics system
US20070095159A1 (en) * 2003-07-18 2007-05-03 C2 Diagnostics Sampling device and method for an automatic analyser
US7377189B2 (en) * 2003-07-18 2008-05-27 C2 Diagnostics Sampling device and method for an automatic analyser
US8545913B2 (en) * 2004-04-09 2013-10-01 Nestec S.A. Process for preparing, prior to filling, a wafer cornet, cornet thus obtained and installation for implementing the process
US20070204571A1 (en) * 2004-04-09 2007-09-06 Nestec S.A. Process for preparing, prior to filling, a wafer cornet, cornet thus obtained and installation for implementing the process
US20050281713A1 (en) * 2004-06-18 2005-12-22 Bioanalytical Systems, Inc. (An Indiana Company) System and method for sample collection
US20060266766A1 (en) * 2005-05-26 2006-11-30 Peter Andrews Fluid-dispensing apparatus with controlled tear-off and methods of using the same
US7681759B2 (en) * 2005-05-26 2010-03-23 Cree, Inc. Fluid-dispensing apparatus with controlled tear-off
US20140290341A1 (en) * 2011-08-03 2014-10-02 Becton, Dickinson And Company Detection of a Compromised Flow Line in a Laboratory Instrument
JPWO2014112591A1 (ja) * 2013-01-21 2017-01-19 株式会社日立ハイテクノロジーズ 自動分析装置
WO2014112591A1 (ja) * 2013-01-21 2014-07-24 株式会社日立ハイテクノロジーズ 自動分析装置
CN104903729A (zh) * 2013-01-21 2015-09-09 株式会社日立高新技术 自动分析装置
US9891241B2 (en) 2013-01-21 2018-02-13 Hitachi High-Technologies Corporation Automatic analysis device
EP2947463A4 (en) * 2013-01-21 2017-01-11 Hitachi High-Technologies Corporation Automatic analysis device
CN105917238A (zh) * 2014-01-24 2016-08-31 株式会社日立高新技术 自动分析装置
CN105917238B (zh) * 2014-01-24 2017-09-26 株式会社日立高新技术 自动分析装置
CN105327907A (zh) * 2015-12-14 2016-02-17 重庆南方数控设备有限责任公司 一种用于清洗采样针的涡流式洗针装置
US11156628B2 (en) * 2017-02-24 2021-10-26 Hitachi High-Tech Corporation Automatic analyzer
CN108856181A (zh) * 2018-04-28 2018-11-23 深圳市亚辉龙生物科技股份有限公司 磁分离用吸液针清洁方法及应用该方法的清洗设备
CN110877040A (zh) * 2019-11-20 2020-03-13 香港大德昌龙生物科技有限公司 加样针清洗设备及加样针清洗的方法、应用
CN110877040B (zh) * 2019-11-20 2021-07-20 香港大德昌龙生物科技有限公司 加样针清洗设备及加样针清洗的方法、应用

Also Published As

Publication number Publication date
SE336241B (en, 2012) 1971-06-28
GB1213421A (en) 1970-11-25

Similar Documents

Publication Publication Date Title
US3552212A (en) Device for cleaning the exterior of an elongated body
US3836329A (en) Method and apparatus for removing liquid from containers
US4730631A (en) Probe wash station
US6422248B1 (en) Device for cleaning pipette needles or stirrers
US4528158A (en) Automatic sampling system
US5603342A (en) Apparatus for cleaning a fluid sample probe
US3842680A (en) Gas blast wiping collar for cleaning pipettes
JPS626176B2 (en, 2012)
US5279794A (en) Probe washing unit and automatic analysis system having probe washing unit
ATE128242T1 (de) Reinigungsverfahren und vorrichtung für reagenzverteilungspipetten.
WO2002016039A1 (fr) Pipette a tete jetable
CN108700610B (zh) 自动分析装置及清洗方法
US4015938A (en) Sample supply apparatus and method for automatic analysis systems
US3252327A (en) Sample supply device for automatic analysis apparatus
CA2239974A1 (en) Apparatus and method for washing a pipette probe
USRE39600E1 (en) Liquid sample dispensing methods for precisely delivering liquids without crossover
JPH09184846A (ja) 液体試料分注装置
JPS61234336A (ja) 分注装置
US12174210B2 (en) Automated analyzer and cleaning method
SU717996A3 (ru) Устройство дл подачи проб в системе непрерывного анализа потока жидкости
JP2796352B2 (ja) 粒子計数装置
US12203953B2 (en) Helix wash station that augments the fluid dynamics associated with clinical chemistry and immunoassay probe cleaning
JPH02223860A (ja) サンプリング管洗浄装置
WO2020262361A1 (ja) 自動分析装置
HK40083329A (en) A helix wash station that augments the fluid dynamics associated with clinical chemistry and immunoassay probe cleaning