US3167397A - Panel mounting for tubing and accessories for analysis apparatus - Google Patents

Panel mounting for tubing and accessories for analysis apparatus Download PDF

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Publication number
US3167397A
US3167397A US197421A US19742162A US3167397A US 3167397 A US3167397 A US 3167397A US 197421 A US197421 A US 197421A US 19742162 A US19742162 A US 19742162A US 3167397 A US3167397 A US 3167397A
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US
United States
Prior art keywords
pump
panel
tubes
sample
accessories
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
US197421A
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English (en)
Inventor
Leonard T Skeggs
Blanche R Stuart
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer Corp
Original Assignee
Technicon Instruments Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to BE631781D priority Critical patent/BE631781A/xx
Application filed by Technicon Instruments Corp filed Critical Technicon Instruments Corp
Priority to US197421A priority patent/US3167397A/en
Priority to GB15473/63A priority patent/GB997030A/en
Priority to CH628263A priority patent/CH457911A/de
Priority to DE19631523054 priority patent/DE1523054B2/de
Application granted granted Critical
Publication of US3167397A publication Critical patent/US3167397A/en
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

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Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N1/00—Sampling; Preparing specimens for investigation
    • G01N1/02—Devices for withdrawing samples
    • G01N1/10—Devices for withdrawing samples in the liquid or fluent state
    • G01N1/18—Devices for withdrawing samples in the liquid or fluent state with provision for splitting samples into portions
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
    • B01L9/00—Supporting devices; Holding devices
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B43/00—Machines, pumps, or pumping installations having flexible working members
    • F04B43/12—Machines, pumps, or pumping installations having flexible working members having peristaltic action
    • F04B43/1223—Machines, pumps, or pumping installations having flexible working members having peristaltic action the actuating elements, e.g. rollers, moving in a straight line during squeezing
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
    • G01N35/08—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a stream of discrete samples flowing along a tube system, e.g. flow injection analysis

Definitions

  • This invention relates to automatic analysis apparatus and, more particularly, to an accessory panel for use with such apparatus.
  • a sample liquid is transmitted through the apparatus in the form of a stream and is treated with various streams of processing fluids and reagents for treating the sample to determine the quantity of a constituent thereof.
  • processing fluids and reagents vary depending upon the particular quantitative analysis of the sample, so that in the use of the apparatus for various analyses, the apparatus must be provided with various accessories which must be arranged according to the procedure established by the particular analysis. This involves the provision and arrangement of various pump tubes, mixing coils, connecting tubes, and other accessories which involves considerable time and effort, especially when only one analysis apparatus is available for performing various analyses.
  • One object of the present invention is the provision of means which are to be used in conjunction with an analysis apparatus and which provide accessories arranged according to a preestablished procedure for a particular analysis to eliminate the time and eflort heretofore required for arranging the apparatus for said particular analysis.
  • a further object is the provision of an accessory panel which can be readily mounted on the pump housing of the analysis apparatus and which carries the necessary accessories performing a particular analysis.
  • FIG. 1 is a top plan view of the accessory panel mounted on a pump of an analysis apparatus
  • FIG. 2 is a vertical sectional view taken on line 22 of FIG. 1;
  • FIG. 3 is a vertical sectional view, similar to FIG. 2, but illustrating the panel removed from the pump;
  • FIG. 4 is a perspective view of part of a mixing coil and its associated mounting clamp
  • FIG. 5 is a vertical sectional view, on a larger scale, taken on line 5-5 of FIG. 1;
  • FIG. 6 is a horizontal sectional view, on a larger scale, taken on line 6-6 of FIG. 2;
  • FIG. 7 is a vertical sectional view, on a larger scale, taken on line 77 of FIG. 2;
  • FIG. 8 is a perspective view of part of the panel and part of a pump housing, illustrating the operational relation therebetween;
  • FIG. 9 is a perspective view of a part of the accessory panel.
  • the accessory panel comprises a plate 10 which is adapted to be removably mounted on the upper surface of the housing or frame 12 of a proportional pump 14 of an analysis system ofthe type described in the above mentioned US. Patent No. 2,797,149.
  • the pump is preferably of the type shown in US. Patent No. 2,935,028, issued May 3, 1960, and has a series of longitudinally spaced, transversely extending pressure rollers 16 which are carried by an endless chainconveyor 18 for compressinga series of resiliently flexible pump tubes 20 against the pump platen 22 to simultaneously collapse the pump tubes as the rollers move longitudinally thereof for propelling the fluids, in proportional amounts, through their respective pump tubes for the pumping operation.
  • the plate has an opening 24 having the configuration shown in FIG. 1 through which the aforementioned parts of the pump extend when the accessory panel is mounted on the housing of the pump, as best seen in FIG. 2.
  • the side edges of the plate have downturned flanges 26 which are adapted to engage the upper marginal side edge portions of the housing of the pump and the plate can be provided with bayonet slots 28 for interengaging screws 30 provided in the top of the pump housing for releasably mounting the panel on thelatter.
  • One end of the plate has an upturned flange 32 which carries a tube connecting device 34 carrying nipples 36 to which tubes can be connected for introducing the sample and processing fluids into the analysis system.
  • the tube connecting device comprises a pair of spaced plates 38 which are operatively connected to each other by screws 40 and the inner plate 38a is suitably secured to flange 32.
  • Each nipple 36 is connected to one end of a companion tube 42 and the opposite end of the tube extends through a hole 44 in plate 38-12.
  • the hole has an enlarged bore 46 and the enlarged opposite end 48 of the tube fits in said bore.
  • Plate 33a is constructed in the same manner as plate 38b and carries tube 42' in axial alignment with the companion tubes 42 and the enlarged resilient ends 48 of the tubes engage each other by tightening screws 44 and provide a fluid tight connection between companion tubes 42 and 42', While only two inlet nipples 36 have been shown, it will be understood that the number provided depends upon the particular analysis which is to be performed and the required number of processing fluids and reagents which are necessary for said analysis.
  • nipples 36 which are carried by plate 38b preferably are first connected to tubing which supply the reagents from supply bottles and then plate 38b is secured to plate 38a by screws 40 so that all reagent connections are simultaneously made.
  • the sample can be supplied from a tube which need not pass through device 34 but can be conveniently secured to plate 10.
  • the outlet nipples 36' of tubes 42 are connected by suitable tubing 56 to the companion pump tubes 211 for pumping of the sample and processing liquid or reagent from the inlet nipples 36 through the system, and in this regard it will be understood that the number of pump tubes provided depends upon the particular analysis which is to be performed.
  • a pump tube 52 (FIG. 1) is provided having its inlet end 54 exposed to air so that during the operation of the pump, air is transmitted through the pump tube and is introduced into the liquid stream flowing into the adjacent pump tube 56, at the H-shaped fitting 53 to form a segmented stream comprising longitudinally spaced liquid segments separated from each other by an intervening gas segment, as described in the aforementioned US. Patent No. 2,797,149.
  • the segmented stream is joined to the other fluid stream flowing through pump tube 59 and tube 59a which can be the sample stream, at T-fitting 60 and the resulting stream is transmitted through tubing 61 to the inlet end of a horizontally mounted helical mixing coil 62.
  • the outlet end of the mixing coil is connected to the inlet end of another mixing coil 64 and the outlet end of the latter mixing coil is connected to the inlet end of a third V 3 V I v mixing coil 66.
  • Theoutlet end of said mixing coil 66 is connected to an outlet nipple 68 so that the treated liquid stream can be transmitted to an analyzer (not shown), for example a colorimeter, by suitable tubing which is connected to nipple 68.
  • the nipple is supported in an' upstanding' flange 70 provided at the end of ,the plate.
  • various tubes are preferably secured to the .top of 'the plate by clamps 74 to prevent extensive movement" of the tubes.
  • a tube clamp 76 extends vertically upwardly from the top'surface of plate and has an upwardly inclined tube bearing surface 78 against which the fitting 58 and tube 59a are clamped I I: cemented to the bottom surface of the panel and has claims.
  • clamping plate'80 which is operated by clamping I 7 screws 82.
  • the clamp has a cutout 84 so that when a large number of pump tubes are needed fora particular analysis, the pump tubes can be spaced vertically from each other to limit the horizontal space which they might otherwise occupy on the plate. More specifically, certain of the tubes can be clamped by plate 80 while the remaining pump tubes can extend through cutout V 84. Moreover, by raising the level of certain of the tubes, more space is made available for the T-fitting.60 which need not lie horizontally but can, be positioned vertically or inclined from the vertical. As herein shown, the cutout is not being utilized since the invention is illustrated with a small number of pump tubes.
  • a pair of longitudinally spaced tube holdingmembers 86a and 86b are provided at the inlet and outlet ends, respectively, of the pump tubes 20; Each holding member is provided with a series of open top longitudinally ex-. tending laterally spaced grooves 88 ,in which the corresponding ends of the pump tubes extend.
  • the sides of the holding members are provided with holes 90 and the platen 22 of the pump carries upstanding pinsv 92'which are-adapted to extend into the holes when the panel is mounted on the pump housing, whereby the tube holding means and the pump.
  • the pump is moved into inoperative position by grasping handle 94 and lifting the tube compressing mechanism about its hinge pin 96.
  • the panel is then placed on top of the pump'housing so thepump tubes 20 overlie the platen 22 of the pump and the compressing rollers 16 are above the pump tubes.
  • the tube holding members 86a and 86b are then mounted on pins 90 and the tube cornpressing means of the pump is moved into closed position so that the rollers engage the pump tubes.
  • nipples 36 and the outlet nipple 68 are then connected to the corresponding inlet and outlet tubes for the transmission of the sample and various processing liquids and reagents to the accessories on the'plate 10 for treatment of the sample for analysis.
  • the panel 10 is made of a suitable transparent plastic material and the screws 30 and bayonet slots 28 need not be provided since the flanges 26 Y grasp the upper marginal side edge portions with enough force to prevent longitudinally sliding movement of 'the panel on the pump housing. The longitudinally correct positioning of the panel is easily determined since the panel.
  • a sheet of a suitable material is preferably indicia 94 on its upper surface, .suchas writing, diagrams, identification, etc., which is visible through the transparent panel and identifies the various accessories and indicates the specific manner of practicing the invention. may be made without departing from the underlying idea or principlesof this invention It ithin scope of the appended What is claimed is; l. Apparatus for an analysis system, comprising a pum an accessory panel removably mounted on said pump, said pump having tube compressing means for compressing resiliently flexible pump tubes for pumping fluids through said tubes, respectively, said panel comprising:
  • said plate carrying a series; of resiliently flexible pump tubes forsaid fluids, and for the sample connected to said accessories in fluid flow communication therewith in accordancewith said predetermined arrangement and positioned above and extending across said opening for engagement by said tube compressing means for the pumping operation in said mounted condition of the panel.
  • Apparatus for an' analysis system comprising a pump, an accessory panel removably mounted on said pump, sa d pump having tube compressing means for compressing resiliently flexible pump tubes for pumping flu ds through said tubes, respectively, said panel comprising:
  • said accessories including means for mixing said sample with at least one of said processing fluids
  • said plate carrying a series of resiliently. flexible pump tubes for said fluids and for the sample connected to saidaccessories in fluid flow communication therewith in accordance Withsaid predetermined arrangement and positioned above and extending across said opening for engagement by said tube compressing means for the pumping operation in said. mounted condition of the panel.
  • Apparatus for an analysis system comprising a pump, an accessory panel removably mounted on said; pump, said pump having tube compressing means for compressingresiliently flexiblepump tubes for pumping; fluids through said tubes, respectively, said panel comprising: 7
  • said plate having an opening therein through which said tube compressing means extends in-the mounted condition of said panel on said pump, and (e) saidsplate carryinga series of resiliently flexible pump tubes for said fluids and for the sample con nected to said accessories in fluid flow communication therewith in accordance with said predetermined arrangement and positioned above and extending across said opening for engagement by said tube compressing means for the pumping operation in said mounted condition of the panel.
  • Apparatus for an analysis system comprising a pump, an accessory panel removably mounted on said pump, said pump having tube, compressing means for compressing resiliently flexible pumptubes for pumping fluids through'said tubes, respectively, said panel-comprising: s
  • said accessories including means for mixing said sample with at least one of said processing fluids,
  • said plate having an opening therein through which said tube compressing means extends in the mounted condition of said panel on said pump
  • said plate carrying a series of resiliently flexible pump tubes for said fluids and for the sample connected to said accessories in fluid flow communication therewith in accordance with said predetermined arrangement and positioned above and extending across said opening for engagement by said tube compressing means for the pumping operation in said mounted condition of the panel.
  • Apparatus for an analysis system comprising a pump, an accessory panel removably mounted on said pump, said pump having tube compressing means for compressing resiliently flexible pump tubes for pumping fluids through said tubes, respectively, said panel comprising:
  • said plate carrying a series of resilientlyflexible pump tubes for said fluids and for'the sample connected to said accessories in fluid flow communication therewith in accordance with said predetermined arrangement and positioned above and extending across said opening for engagement by said tube compressing means for the pumping operation in said mounted condition of the panel, and
  • said tube compressing means extends in the system, comprising a 1 -i pu'mp, an; accessory fpanelrernovably'mounted ongsaidl pump, saidgpump having tube :compre'ssingrneans ,for compressing 'resilientlyflexibleg pump tubes for pumping fluids through said tubes, respectively, said panel CORT-.7
  • said plate having indicia identifying said accessories and indicating the interconnection of said.
  • said pump having tube compressing means for compressing resiliently flexible pump tubes .for pumping fluids through, said tubes, respectively, said panel 'com-' prising:
  • said plate carrying a series of'resiliently flexible pumptubesfor said fluidsandfor the, sample connected to said accessories in fluid flow communica'tiontherewith in accordance with said predetermined arrangement and' positioned above and extending across said opening for engagement by said tube compressing means for the pumping operation 1 I in'saidmounted conditionof the .panel, and
  • Apparatus for an analysis system comprising a pump, an accessory 'panel-removably mounted onsaid f pump, said pump having tube compressing means for compressing resiliently flexible pump tubesfor pumping fluids through saidl tubes, respectively, said panel com- Pr a (a) a plate'carrying a series of accessories through -which ;a;san 1ple, stream ,and various fluid streams as flow 'for v fluids,"
  • said acoessories including means for mixing said sample w1th;at. least one of'saidprocessingfluids, (e) means for introducing an'inert gaseous fluid into said sample liquid stream to divide the latter in' a series of longitudinally spaced liquid segments separated from 'each other .by1an intervening segj ment of said inert gaseous fluid, j (f) said plate having an opening therein through which said tube compressing means extends in the mounted 'condition'of said panelionlsaid pump, (g) said plate carrying' a series-of resiliently'flexible 1 pump tubes for; said fluids-and for'the sample connected to said accessories; inyfluidiflow communicationfjtherewithx in accordance with said :predeten" mmedarrangement; and positioned above and extending across said opening for engagement by said tube compressing means for the pumping-operation v in said mounted condition of the panel, and (h), tube holding means longitudinally spaced from each other for holding
  • Apparatus for an analysis system comprising: (a) a pump having a frame and tube compressing means for compressing a plurality of resiliently flexible pump tubes for pumping a sample stream and a processing fluid stream through said system for treatment of said sample by said processing fluid, and
  • said panel having a series of pump tubes extending longitudinally across said opening for engagement by said tube compressing means for the pumping of said sample and processing fluid
  • said last mentioned means including mixing means for mixing said sample with said processing fluid.
  • Apparatus for an analysis system comprising a pump, an accessory panel removably mounted on said pump, said panel comprising:
  • said plate carrying a series of resiliently flexible pump tubes for said fluids and for the sample connected to said accessories in fluid flow communication therewith in accordance with said predetermined arrangement for the pumping of said fluids and samples, and
  • tube connecting means positioned on said plate for the transmission of fluids to and from said panel, said tube connecting means being spaced from each other longitudinally of said tubes, said plate having an opening between said tube connecting means providing access of tube compressing means to said tubes for the pumping operation.

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  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Engineering & Computer Science (AREA)
  • General Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Mechanical Engineering (AREA)
  • General Engineering & Computer Science (AREA)
  • Hydrology & Water Resources (AREA)
  • Clinical Laboratory Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Reciprocating Pumps (AREA)
US197421A 1962-05-24 1962-05-24 Panel mounting for tubing and accessories for analysis apparatus Expired - Lifetime US3167397A (en)

Priority Applications (5)

Application Number Priority Date Filing Date Title
BE631781D BE631781A (it) 1962-05-24
US197421A US3167397A (en) 1962-05-24 1962-05-24 Panel mounting for tubing and accessories for analysis apparatus
GB15473/63A GB997030A (en) 1962-05-24 1963-04-19 Panel for pre-arranged interconnection and mounting of tubing and accessories for use with a proportioning pump
CH628263A CH457911A (de) 1962-05-24 1963-05-20 Zusatzgerät zu einem Analysenautomaten
DE19631523054 DE1523054B2 (de) 1962-05-24 1963-05-20 Zubehöranordnung für ein Analysengerät

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US197421A US3167397A (en) 1962-05-24 1962-05-24 Panel mounting for tubing and accessories for analysis apparatus

Publications (1)

Publication Number Publication Date
US3167397A true US3167397A (en) 1965-01-26

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US197421A Expired - Lifetime US3167397A (en) 1962-05-24 1962-05-24 Panel mounting for tubing and accessories for analysis apparatus

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US (1) US3167397A (it)
BE (1) BE631781A (it)
CH (1) CH457911A (it)
DE (1) DE1523054B2 (it)
GB (1) GB997030A (it)

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3615234A (en) * 1968-05-28 1971-10-26 Technicon Corp System for processing and analyzing biological samples
US4184815A (en) * 1977-03-14 1980-01-22 Extracorporeal Medical Specialties, Inc. Roller pump rotor with integral spring arms
US4233001A (en) * 1979-02-28 1980-11-11 Peerless Electronics Research Corporation Peristaltic pump
US4346863A (en) * 1980-02-07 1982-08-31 General Motors Corporation Attachment device for a brake hose
US5134079A (en) * 1989-03-27 1992-07-28 International Technidyne Corp. Fluid sample collection and delivery system and methods particularly adapted for body fluid sampling
US5447417A (en) * 1993-08-31 1995-09-05 Valleylab Inc. Self-adjusting pump head and safety manifold cartridge for a peristaltic pump
US9863837B2 (en) 2013-12-18 2018-01-09 OptiScan Biomedical Coporation Systems and methods for detecting leaks

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2570617B1 (fr) * 1984-09-26 1986-12-26 Nal Transfusion Sanguine Centr Melangeur a duree de contact definie et reproductible entre une phase liquide et au moins une autre phase liquide ou solide

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1570834A (en) * 1923-06-14 1926-01-26 United States Radium Corp Method of and apparatus for purification of radium emanation
US2658819A (en) * 1949-08-23 1953-11-10 John M Formwalt Apparatus for measuring chemical activity, particularly of catalysts
US2797149A (en) * 1953-01-08 1957-06-25 Technicon International Ltd Methods of and apparatus for analyzing liquids containing crystalloid and non-crystalloid constituents
US2935028A (en) * 1957-08-05 1960-05-03 Technicon Instr Pumps

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1570834A (en) * 1923-06-14 1926-01-26 United States Radium Corp Method of and apparatus for purification of radium emanation
US2658819A (en) * 1949-08-23 1953-11-10 John M Formwalt Apparatus for measuring chemical activity, particularly of catalysts
US2797149A (en) * 1953-01-08 1957-06-25 Technicon International Ltd Methods of and apparatus for analyzing liquids containing crystalloid and non-crystalloid constituents
US2935028A (en) * 1957-08-05 1960-05-03 Technicon Instr Pumps

Cited By (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3615234A (en) * 1968-05-28 1971-10-26 Technicon Corp System for processing and analyzing biological samples
US4184815A (en) * 1977-03-14 1980-01-22 Extracorporeal Medical Specialties, Inc. Roller pump rotor with integral spring arms
US4233001A (en) * 1979-02-28 1980-11-11 Peerless Electronics Research Corporation Peristaltic pump
US4346863A (en) * 1980-02-07 1982-08-31 General Motors Corporation Attachment device for a brake hose
US5134079A (en) * 1989-03-27 1992-07-28 International Technidyne Corp. Fluid sample collection and delivery system and methods particularly adapted for body fluid sampling
US5447417A (en) * 1993-08-31 1995-09-05 Valleylab Inc. Self-adjusting pump head and safety manifold cartridge for a peristaltic pump
US9863837B2 (en) 2013-12-18 2018-01-09 OptiScan Biomedical Coporation Systems and methods for detecting leaks

Also Published As

Publication number Publication date
BE631781A (it)
DE1523054A1 (de) 1968-11-28
GB997030A (en) 1965-06-30
CH457911A (de) 1968-06-15
DE1523054B2 (de) 1970-09-17

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