US20240156707A1 - Hair growth essence and its preparation method - Google Patents
Hair growth essence and its preparation method Download PDFInfo
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- US20240156707A1 US20240156707A1 US17/985,927 US202217985927A US2024156707A1 US 20240156707 A1 US20240156707 A1 US 20240156707A1 US 202217985927 A US202217985927 A US 202217985927A US 2024156707 A1 US2024156707 A1 US 2024156707A1
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- Prior art keywords
- hair growth
- present
- peg
- skin
- blue copper
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- 230000003779 hair growth Effects 0.000 title claims abstract description 27
- 238000002360 preparation method Methods 0.000 title claims abstract description 13
- MVORZMQFXBLMHM-QWRGUYRKSA-N Gly-His-Lys Chemical compound NCCCC[C@@H](C(O)=O)NC(=O)[C@@H](NC(=O)CN)CC1=CN=CN1 MVORZMQFXBLMHM-QWRGUYRKSA-N 0.000 claims abstract description 30
- YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 claims abstract description 23
- 241000530268 Lycaena heteronea Species 0.000 claims abstract description 18
- 229920002565 Polyethylene Glycol 400 Polymers 0.000 claims abstract description 17
- WHMDKBIGKVEYHS-IYEMJOQQSA-L Zinc gluconate Chemical compound [Zn+2].OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O.OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C([O-])=O WHMDKBIGKVEYHS-IYEMJOQQSA-L 0.000 claims abstract description 12
- 229960000306 zinc gluconate Drugs 0.000 claims abstract description 12
- 235000011478 zinc gluconate Nutrition 0.000 claims abstract description 12
- 239000011670 zinc gluconate Substances 0.000 claims abstract description 12
- 229960002685 biotin Drugs 0.000 claims abstract description 11
- 235000020958 biotin Nutrition 0.000 claims abstract description 11
- 239000011616 biotin Substances 0.000 claims abstract description 11
- SNPLKNRPJHDVJA-ZETCQYMHSA-N D-panthenol Chemical compound OCC(C)(C)[C@@H](O)C(=O)NCCCO SNPLKNRPJHDVJA-ZETCQYMHSA-N 0.000 claims abstract description 9
- 229940101267 panthenol Drugs 0.000 claims abstract description 9
- 235000020957 pantothenol Nutrition 0.000 claims abstract description 9
- 239000011619 pantothenol Substances 0.000 claims abstract description 9
- QCDWFXQBSFUVSP-UHFFFAOYSA-N 2-phenoxyethanol Chemical compound OCCOC1=CC=CC=C1 QCDWFXQBSFUVSP-UHFFFAOYSA-N 0.000 claims abstract description 8
- 229960005323 phenoxyethanol Drugs 0.000 claims abstract description 8
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 8
- 239000004615 ingredient Substances 0.000 claims abstract description 7
- RHGKLRLOHDJJDR-BYPYZUCNSA-N L-citrulline Chemical compound NC(=O)NCCC[C@H]([NH3+])C([O-])=O RHGKLRLOHDJJDR-BYPYZUCNSA-N 0.000 claims abstract description 6
- RHGKLRLOHDJJDR-UHFFFAOYSA-N Ndelta-carbamoyl-DL-ornithine Natural products OC(=O)C(N)CCCNC(N)=O RHGKLRLOHDJJDR-UHFFFAOYSA-N 0.000 claims abstract description 6
- 229960002173 citrulline Drugs 0.000 claims abstract description 6
- 235000013477 citrulline Nutrition 0.000 claims abstract description 6
- 238000009472 formulation Methods 0.000 claims abstract description 6
- 239000000203 mixture Substances 0.000 claims abstract description 6
- MXOAEAUPQDYUQM-QMMMGPOBSA-N (S)-chlorphenesin Chemical compound OC[C@H](O)COC1=CC=C(Cl)C=C1 MXOAEAUPQDYUQM-QMMMGPOBSA-N 0.000 claims abstract description 4
- 229960003993 chlorphenesin Drugs 0.000 claims abstract description 4
- 229940041984 dextran 1 Drugs 0.000 claims abstract description 4
- 238000003756 stirring Methods 0.000 claims description 6
- 238000004519 manufacturing process Methods 0.000 claims description 4
- 238000004140 cleaning Methods 0.000 claims description 3
- 238000001816 cooling Methods 0.000 claims description 3
- 230000003247 decreasing effect Effects 0.000 claims description 3
- 238000007599 discharging Methods 0.000 claims description 3
- 238000007689 inspection Methods 0.000 claims description 3
- 239000000463 material Substances 0.000 claims description 3
- 238000005070 sampling Methods 0.000 claims description 3
- 238000005303 weighing Methods 0.000 claims description 3
- 230000000694 effects Effects 0.000 abstract description 15
- 210000004209 hair Anatomy 0.000 abstract description 13
- 230000008439 repair process Effects 0.000 abstract description 6
- 230000001737 promoting effect Effects 0.000 abstract description 5
- 230000037384 skin absorption Effects 0.000 abstract description 5
- 231100000274 skin absorption Toxicity 0.000 abstract description 5
- UYTPUPDQBNUYGX-UHFFFAOYSA-N guanine Chemical compound O=C1NC(N)=NC2=C1N=CN2 UYTPUPDQBNUYGX-UHFFFAOYSA-N 0.000 abstract description 4
- 230000004060 metabolic process Effects 0.000 abstract description 4
- 231100000252 nontoxic Toxicity 0.000 abstract description 4
- 230000003000 nontoxic effect Effects 0.000 abstract description 4
- 239000002075 main ingredient Substances 0.000 abstract description 3
- 210000003491 skin Anatomy 0.000 description 19
- 239000002453 shampoo Substances 0.000 description 6
- 201000004384 Alopecia Diseases 0.000 description 5
- 208000024963 hair loss Diseases 0.000 description 5
- 239000002994 raw material Substances 0.000 description 4
- WSFSSNUMVMOOMR-UHFFFAOYSA-N Formaldehyde Chemical compound O=C WSFSSNUMVMOOMR-UHFFFAOYSA-N 0.000 description 3
- 239000003795 chemical substances by application Substances 0.000 description 3
- -1 fatty alcohol sulfate Chemical class 0.000 description 3
- 230000006870 function Effects 0.000 description 3
- 230000003676 hair loss Effects 0.000 description 3
- 239000003755 preservative agent Substances 0.000 description 3
- 230000002335 preservative effect Effects 0.000 description 3
- 230000002265 prevention Effects 0.000 description 3
- 208000001840 Dandruff Diseases 0.000 description 2
- 206010061218 Inflammation Diseases 0.000 description 2
- NIPNSKYNPDTRPC-UHFFFAOYSA-N N-[2-oxo-2-(2,4,6,7-tetrahydrotriazolo[4,5-c]pyridin-5-yl)ethyl]-2-[[3-(trifluoromethoxy)phenyl]methylamino]pyrimidine-5-carboxamide Chemical compound O=C(CNC(=O)C=1C=NC(=NC=1)NCC1=CC(=CC=C1)OC(F)(F)F)N1CC2=C(CC1)NN=N2 NIPNSKYNPDTRPC-UHFFFAOYSA-N 0.000 description 2
- 238000010521 absorption reaction Methods 0.000 description 2
- 230000015572 biosynthetic process Effects 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- KWIUHFFTVRNATP-UHFFFAOYSA-N glycine betaine Chemical compound C[N+](C)(C)CC([O-])=O KWIUHFFTVRNATP-UHFFFAOYSA-N 0.000 description 2
- 230000003752 improving hair Effects 0.000 description 2
- NOESYZHRGYRDHS-UHFFFAOYSA-N insulin Chemical compound N1C(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(NC(=O)CN)C(C)CC)CSSCC(C(NC(CO)C(=O)NC(CC(C)C)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CCC(N)=O)C(=O)NC(CC(C)C)C(=O)NC(CCC(O)=O)C(=O)NC(CC(N)=O)C(=O)NC(CC=2C=CC(O)=CC=2)C(=O)NC(CSSCC(NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2C=CC(O)=CC=2)NC(=O)C(CC(C)C)NC(=O)C(C)NC(=O)C(CCC(O)=O)NC(=O)C(C(C)C)NC(=O)C(CC(C)C)NC(=O)C(CC=2NC=NC=2)NC(=O)C(CO)NC(=O)CNC2=O)C(=O)NCC(=O)NC(CCC(O)=O)C(=O)NC(CCCNC(N)=N)C(=O)NCC(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC=CC=3)C(=O)NC(CC=3C=CC(O)=CC=3)C(=O)NC(C(C)O)C(=O)N3C(CCC3)C(=O)NC(CCCCN)C(=O)NC(C)C(O)=O)C(=O)NC(CC(N)=O)C(O)=O)=O)NC(=O)C(C(C)CC)NC(=O)C(CO)NC(=O)C(C(C)O)NC(=O)C1CSSCC2NC(=O)C(CC(C)C)NC(=O)C(NC(=O)C(CCC(N)=O)NC(=O)C(CC(N)=O)NC(=O)C(NC(=O)C(N)CC=1C=CC=CC=1)C(C)C)CC1=CN=CN1 NOESYZHRGYRDHS-UHFFFAOYSA-N 0.000 description 2
- 239000002932 luster Substances 0.000 description 2
- WSFSSNUMVMOOMR-NJFSPNSNSA-N methanone Chemical compound O=[14CH2] WSFSSNUMVMOOMR-NJFSPNSNSA-N 0.000 description 2
- 231100000957 no side effect Toxicity 0.000 description 2
- 210000004927 skin cell Anatomy 0.000 description 2
- 238000004659 sterilization and disinfection Methods 0.000 description 2
- 239000000126 substance Substances 0.000 description 2
- HHVIBTZHLRERCL-UHFFFAOYSA-N sulfonyldimethane Chemical compound CS(C)(=O)=O HHVIBTZHLRERCL-UHFFFAOYSA-N 0.000 description 2
- 239000004094 surface-active agent Substances 0.000 description 2
- 208000024891 symptom Diseases 0.000 description 2
- 238000003786 synthesis reaction Methods 0.000 description 2
- VVFYQBFGXTYSMW-UHFFFAOYSA-N 1-chloro-1-phenoxyethanol Chemical compound CC(O)(Cl)OC1=CC=CC=C1 VVFYQBFGXTYSMW-UHFFFAOYSA-N 0.000 description 1
- 208000002874 Acne Vulgaris Diseases 0.000 description 1
- QGZKDVFQNNGYKY-UHFFFAOYSA-O Ammonium Chemical compound [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- 102000008186 Collagen Human genes 0.000 description 1
- 108010035532 Collagen Proteins 0.000 description 1
- 229920002307 Dextran Polymers 0.000 description 1
- 241000196324 Embryophyta Species 0.000 description 1
- AVXURJPOCDRRFD-UHFFFAOYSA-N Hydroxylamine Chemical compound ON AVXURJPOCDRRFD-UHFFFAOYSA-N 0.000 description 1
- 206010020772 Hypertension Diseases 0.000 description 1
- 102000004877 Insulin Human genes 0.000 description 1
- 108090001061 Insulin Proteins 0.000 description 1
- AYRXSINWFIIFAE-SCLMCMATSA-N Isomaltose Natural products OC[C@H]1O[C@H](OC[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)C=O)[C@@H](O)[C@@H](O)[C@@H]1O AYRXSINWFIIFAE-SCLMCMATSA-N 0.000 description 1
- 239000004166 Lanolin Substances 0.000 description 1
- 208000002720 Malnutrition Diseases 0.000 description 1
- MMBILEWCGWTAOV-UHFFFAOYSA-N N-(2-Hydroxypropyl)dodecanamide Chemical compound CCCCCCCCCCCC(=O)NCC(C)O MMBILEWCGWTAOV-UHFFFAOYSA-N 0.000 description 1
- 229920003171 Poly (ethylene oxide) Polymers 0.000 description 1
- 239000002202 Polyethylene glycol Substances 0.000 description 1
- 208000003251 Pruritus Diseases 0.000 description 1
- QAOWNCQODCNURD-UHFFFAOYSA-L Sulfate Chemical compound [O-]S([O-])(=O)=O QAOWNCQODCNURD-UHFFFAOYSA-L 0.000 description 1
- UCKMPCXJQFINFW-UHFFFAOYSA-N Sulphide Chemical compound [S-2] UCKMPCXJQFINFW-UHFFFAOYSA-N 0.000 description 1
- 208000025371 Taste disease Diseases 0.000 description 1
- GSEJCLTVZPLZKY-UHFFFAOYSA-N Triethanolamine Chemical compound OCCN(CCO)CCO GSEJCLTVZPLZKY-UHFFFAOYSA-N 0.000 description 1
- 229930003756 Vitamin B7 Natural products 0.000 description 1
- 206010048259 Zinc deficiency Diseases 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 206010000496 acne Diseases 0.000 description 1
- 239000000853 adhesive Substances 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
- 230000000172 allergic effect Effects 0.000 description 1
- 150000001412 amines Chemical group 0.000 description 1
- 235000001014 amino acid Nutrition 0.000 description 1
- 150000001413 amino acids Chemical class 0.000 description 1
- 239000003242 anti bacterial agent Substances 0.000 description 1
- 230000000844 anti-bacterial effect Effects 0.000 description 1
- 239000004599 antimicrobial Substances 0.000 description 1
- 239000002216 antistatic agent Substances 0.000 description 1
- 208000010668 atopic eczema Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 229960003237 betaine Drugs 0.000 description 1
- 210000004027 cell Anatomy 0.000 description 1
- 235000019864 coconut oil Nutrition 0.000 description 1
- 239000003240 coconut oil Substances 0.000 description 1
- 229920001436 collagen Polymers 0.000 description 1
- 239000002537 cosmetic Substances 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 230000018109 developmental process Effects 0.000 description 1
- 230000002500 effect on skin Effects 0.000 description 1
- 238000004945 emulsification Methods 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 239000000796 flavoring agent Substances 0.000 description 1
- 235000019634 flavors Nutrition 0.000 description 1
- 239000003205 fragrance Substances 0.000 description 1
- 239000013538 functional additive Substances 0.000 description 1
- 229960004580 glibenclamide Drugs 0.000 description 1
- ZNNLBTZKUZBEKO-UHFFFAOYSA-N glyburide Chemical compound COC1=CC=C(Cl)C=C1C(=O)NCCC1=CC=C(S(=O)(=O)NC(=O)NC2CCCCC2)C=C1 ZNNLBTZKUZBEKO-UHFFFAOYSA-N 0.000 description 1
- 208000037824 growth disorder Diseases 0.000 description 1
- 210000003780 hair follicle Anatomy 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- 230000036571 hydration Effects 0.000 description 1
- 238000006703 hydration reaction Methods 0.000 description 1
- 230000007062 hydrolysis Effects 0.000 description 1
- 238000006460 hydrolysis reaction Methods 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 229940125396 insulin Drugs 0.000 description 1
- 230000007794 irritation Effects 0.000 description 1
- DLRVVLDZNNYCBX-RTPHMHGBSA-N isomaltose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1OC[C@@H]1[C@@H](O)[C@H](O)[C@@H](O)C(O)O1 DLRVVLDZNNYCBX-RTPHMHGBSA-N 0.000 description 1
- 230000007803 itching Effects 0.000 description 1
- 229940039717 lanolin Drugs 0.000 description 1
- 235000019388 lanolin Nutrition 0.000 description 1
- 230000001071 malnutrition Effects 0.000 description 1
- 235000000824 malnutrition Nutrition 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- 208000030159 metabolic disease Diseases 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 230000003020 moisturizing effect Effects 0.000 description 1
- 210000004400 mucous membrane Anatomy 0.000 description 1
- 231100000344 non-irritating Toxicity 0.000 description 1
- 235000015097 nutrients Nutrition 0.000 description 1
- 208000015380 nutritional deficiency disease Diseases 0.000 description 1
- 230000001575 pathological effect Effects 0.000 description 1
- 229920001223 polyethylene glycol Polymers 0.000 description 1
- 229940051841 polyoxyethylene ether Drugs 0.000 description 1
- 229920000056 polyoxyethylene ether Polymers 0.000 description 1
- 229920001296 polysiloxane Polymers 0.000 description 1
- 230000003658 preventing hair loss Effects 0.000 description 1
- 108090000765 processed proteins & peptides Proteins 0.000 description 1
- 235000018102 proteins Nutrition 0.000 description 1
- 102000004169 proteins and genes Human genes 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 230000008929 regeneration Effects 0.000 description 1
- 238000011069 regeneration method Methods 0.000 description 1
- 150000003839 salts Chemical class 0.000 description 1
- 230000035807 sensation Effects 0.000 description 1
- 235000019615 sensations Nutrition 0.000 description 1
- 230000037307 sensitive skin Effects 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 150000003384 small molecules Chemical class 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 230000004936 stimulating effect Effects 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 239000011735 vitamin B7 Substances 0.000 description 1
- 235000011912 vitamin B7 Nutrition 0.000 description 1
- 230000029663 wound healing Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
- A61K8/442—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof substituted by amido group(s)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/46—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing sulfur
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/58—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing atoms other than carbon, hydrogen, halogen, oxygen, nitrogen, sulfur or phosphorus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/673—Vitamin B group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/84—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds obtained by reactions otherwise than those involving only carbon-carbon unsaturated bonds
- A61K8/86—Polyethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q5/00—Preparations for care of the hair
- A61Q5/02—Preparations for cleaning the hair
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q7/00—Preparations for affecting hair growth
Definitions
- the present invention relates to the technical field of hair growth essence; in particular, it relates to a hair growth essence and its preparation method.
- Shampoos generally use triethanolamine of fatty alcohol sulfate and mixed salt of hydroxylamine, lauramide mipa, formaldehyde, polyoxyethylene, lanolin, fragrance, color and water as raw materials.
- the basic function of shampoo is to clean, which simply can not solve the problem of pathological dandruff, hair loss, etc., many “functions” are only business marketing gimmicks.
- the focus on the effect of hair softness can make it greasy, dirty and collapsed easily.
- the focus on the effect of hair refreshing can also make the hair rough, dry, fly apart with poor repair performance easily.
- the two mentioned above contradict each other and are difficult to achieve at the same time.
- Surfactants used in shampoo mainly include: sodium fatty alcohol polyoxyethylene ether sulfate AES (ammonium), coconut oil diethanolamide (6501), betaine (CAB35), quaternary amine softener, amino acid surfactant, SLS and some functional additives: silicone slip and shine agent, glyburide anti-dandruff and anti-zooing agent, pearlescent agent, preservative, flavor, color, etc. It is difficult for the existing shampoo to provide better care effect, therefore, there is a need to design a plant peptide shampoo.
- the purpose of the present invention is to provide a hair growth essence and its preparation method.
- the present invention relates to a hair growth essence, including the following weight percentages of each component:
- PEG-400 covered by the present invention is polyethylene glycol, which is non-toxic, non-irritating, with goodwater solubility, and is well soluble in many organic components.
- the invention employs PEG-400, which will be fully compatible with other components and fully dissolved; in addition, the PEG-400 covered by the present invention has excellent lubricity. Moisturizing property, dispersivity; it is used in the components of the present invention to give full play to its excellent properties for adhesive, antistatic agent and softener, etc.
- Dextran covered by the present invention has high specific rotation; partial hydrolysis mainly yields isomaltose. Provides a shiny feeling to the hair growth.
- Guanine covered by the present invention is an effective substance with health care function, which can improve the immunity of human body; it also has the effect of treating high blood pressure and reducing body fatigue.
- MSM covered by the present invention is dimethyl sulfone, an organic sulfide, which has the ability to enhance the production of insulin in human body while playing a role in promoting the metabolism of sugar.
- Biotin tripeptide-1 covered by the present invention is a tripeptide combining vitamin H and Matrikine series GHK, which can stimulate the synthesis of collagen and laminin, and fix the hair in the dermal hair follicle to prevent hair loss.
- Blue copper peptide covered by the present invention is blue copper peptide, which has the effect of improving skin repair ability, promoting skin absorption and deep skin wake-up, etc., specifically:
- Panthenol covered by the present invention can promote wound healing and anti-inflammation; the application of panthenol on hair can play a role in hair care, which can also prevent hair splitting as well as increase the density of hair and improve the luster of hair.
- Zinc gluconate covered by the present invention is usually able to treat patients with abnormal taste and metabolic disorders caused by zinc deficiency, and is also effective in the treatment of acne and malnutrition. This drug is mainly based on zinc gluconate, after taking this drug, it is beneficial for the absorption of nutrients in the body and the intelligence of children can also be improved. It can also accelerate growth and development and prevent the symptoms of stunting.
- Phenoxyethanol covered by the present invention is a preservative with low skin sensitivity, it is added to cosmetics to act as an antibacterial and antiseptic agent and may also have a certain degree of emulsification effect that affects the viscosity of skin care products, which is a fairly safe preservative. It is employed as a substitute for formaldehyde, as formaldehyde is quite irritating, and after replacing it with phenoxyethanol, the irritation and damage to human body is significantly reduced. For some people with sensitive skin, the presence of a slight local burning and searing sensation may still occur. Sometimes it may be irritating to use the mucous membrane area of the eyes, and products containing phenoxyethanol should be avoided. However, in general, phenoxyethanol is still safe for the skin.
- Chlorophenoxyethanol covered by the present invention can mainly play the role of disinfection and sterilization, and can inhibit the growth of many bacteria, so it can play the role of hair care.
- the addition of this component to the hair growth essence covered by the present invention can eliminate some symptoms of inflammation, such as a certain degree of relief for redness and itching to avoidance of unsafe use for allergic bodies.
- the present invention also relates to the aforementioned preparation method of the hair growth essence, including the following steps:
- the present example relates to a hair growth essence, including the following weight percentages of each component:
- the present invention also relates to the aforementioned preparation method of the hair growth essence, including the following steps:
- the preparation process is basically the same as that of example 1, the only difference is the absence of PEG-400, blue copper peptide, panthenol and zinc gluconate in the raw materials used to prepare the hair growth essence.
- the preparation process is basically the same as that of example 1, the only difference is the absence of PEG-400, biotin tripeptide-1, panthenol and zinc gluconate in the raw materials used to prepare the hair growth essence.
- the preparation process is basically the same as that of example 1, the only difference is the absence of PEG-400, biotin tripeptide-1 and blue copper peptide in the raw materials used to prepare the hair growth essence.
- example 1 The effect of example 1 is compared with the effect of comparison example 1-3, see Table 1.
- PEG-400, biotin tripeptide-1, blue copper peptide, panthenol and zinc gluconate act synergistically during the use of the hair growth essence, synergistically increasing hair loss prevention rate and hair growth promotion rate.
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Abstract
The present invention provides a hair growth essence and its preparation method; including the following weight percentages of each component: water 89.24%, PEG-400 7%, dextran 1%, guanine 0.5%, MSM 1%, biotin tripeptide-1 0.01%, blue copper peptide 0.35%, panthenol 0.5%, zinc gluconate 0.1%, phenoxyethanol 0.15%, chlorphenesin 0.15%. The present invention also relates to the aforementioned preparation method of the hair growth essence. The components covered by the present invention are safe and non-toxic, the formulation is reasonable, containing effective ingredients such as PEG-400, citrulline, biotin tripeptide-1, blue copper peptide and zinc gluconate; it can effectively strengthen hair roots, regulate metabolism and promote new hair growth, while the main ingredient PEG-400 has a dispersive effect; blue copper peptide has the effect of improving skin repair ability, promoting skin absorption, deep skin wake-up and so on.
Description
- The present invention relates to the technical field of hair growth essence; in particular, it relates to a hair growth essence and its preparation method.
- Shampoos generally use triethanolamine of fatty alcohol sulfate and mixed salt of hydroxylamine, lauramide mipa, formaldehyde, polyoxyethylene, lanolin, fragrance, color and water as raw materials. The basic function of shampoo is to clean, which simply can not solve the problem of pathological dandruff, hair loss, etc., many “functions” are only business marketing gimmicks. For the current shampoo on the market, the focus on the effect of hair softness can make it greasy, dirty and collapsed easily. The focus on the effect of hair refreshing can also make the hair rough, dry, fly apart with poor repair performance easily. The two mentioned above contradict each other and are difficult to achieve at the same time. Surfactants used in shampoo mainly include: sodium fatty alcohol polyoxyethylene ether sulfate AES (ammonium), coconut oil diethanolamide (6501), betaine (CAB35), quaternary amine softener, amino acid surfactant, SLS and some functional additives: silicone slip and shine agent, glyburide anti-dandruff and anti-zooing agent, pearlescent agent, preservative, flavor, color, etc. It is difficult for the existing shampoo to provide better care effect, therefore, there is a need to design a plant peptide shampoo.
- The purpose of the present invention is to provide a hair growth essence and its preparation method.
- The present invention is implemented by the following technical solutions:
- The present invention relates to a hair growth essence, including the following weight percentages of each component:
-
Water 89.24%, PEG-400 7%, Dextran 1%, Citrulline 0.5%, MSM 1%, Biotin tripeptide-1 0.01%, Blue copper peptide 0.35%, Panthenol 0.5%, Zinc gluconate 0.1%, Phenoxyethanol 0.15%, Chlorphenesin 0.15%. - The role of each of the components mentioned above in the present invention is as follows: PEG-400 covered by the present invention is polyethylene glycol, which is non-toxic, non-irritating, with goodwater solubility, and is well soluble in many organic components. The invention employs PEG-400, which will be fully compatible with other components and fully dissolved; in addition, the PEG-400 covered by the present invention has excellent lubricity. Moisturizing property, dispersivity; it is used in the components of the present invention to give full play to its excellent properties for adhesive, antistatic agent and softener, etc.
- Dextran covered by the present invention has high specific rotation; partial hydrolysis mainly yields isomaltose. Provides a shiny feeling to the hair growth.
- Guanine covered by the present invention is an effective substance with health care function, which can improve the immunity of human body; it also has the effect of treating high blood pressure and reducing body fatigue.
- MSM covered by the present invention is dimethyl sulfone, an organic sulfide, which has the ability to enhance the production of insulin in human body while playing a role in promoting the metabolism of sugar.
- Biotin tripeptide-1 covered by the present invention is a tripeptide combining vitamin H and Matrikine series GHK, which can stimulate the synthesis of collagen and laminin, and fix the hair in the dermal hair follicle to prevent hair loss.
- Blue copper peptide covered by the present invention is blue copper peptide, which has the effect of improving skin repair ability, promoting skin absorption and deep skin wake-up, etc., specifically:
-
- (1) Improve skin repair ability: blue copper peptide can promote the synthesis of skin matrix and enhance the regeneration ability of skin cell tissue, so that the skin can heal quickly when it is damaged.
- (2) Promote skin absorption: the molecular structure of blue copper peptide is small, and most of them are small molecule proteins, which can be easily absorbed by skin, so the absorption and utilization of effective ingredients by skin can be accelerated by adding this substance in skin care products.
- (3) Deep skin wake-up: when blue copper peptide penetrates into the bottom layer of skin, it is good for stimulating the vitality of cells, enhancing the activity of deep skin cells, making the skin soft and elastic, and regular use can help improve the luster and hydration of the skin.
- Panthenol covered by the present invention can promote wound healing and anti-inflammation; the application of panthenol on hair can play a role in hair care, which can also prevent hair splitting as well as increase the density of hair and improve the luster of hair. Zinc gluconate covered by the present invention is usually able to treat patients with abnormal taste and metabolic disorders caused by zinc deficiency, and is also effective in the treatment of acne and malnutrition. This drug is mainly based on zinc gluconate, after taking this drug, it is beneficial for the absorption of nutrients in the body and the intelligence of children can also be improved. It can also accelerate growth and development and prevent the symptoms of stunting.
- Phenoxyethanol covered by the present invention is a preservative with low skin sensitivity, it is added to cosmetics to act as an antibacterial and antiseptic agent and may also have a certain degree of emulsification effect that affects the viscosity of skin care products, which is a fairly safe preservative. It is employed as a substitute for formaldehyde, as formaldehyde is quite irritating, and after replacing it with phenoxyethanol, the irritation and damage to human body is significantly reduced. For some people with sensitive skin, the presence of a slight local burning and searing sensation may still occur. Sometimes it may be irritating to use the mucous membrane area of the eyes, and products containing phenoxyethanol should be avoided. However, in general, phenoxyethanol is still safe for the skin.
- Chlorophenoxyethanol covered by the present invention can mainly play the role of disinfection and sterilization, and can inhibit the growth of many bacteria, so it can play the role of hair care. The addition of this component to the hair growth essence covered by the present invention can eliminate some symptoms of inflammation, such as a certain degree of relief for redness and itching to avoidance of unsafe use for allergic bodies.
- The present invention also relates to the aforementioned preparation method of the hair growth essence, including the following steps:
-
- S1, accurately weighing the component materials of the formulation ingredient in proportion to each other, while cleaning the production equipment;
- S2, adding water to the stirring pot, increasing the temperature to 80-83° C., stirring evenly, holding for 20 minutes until completely dissolved, decreasing the temperature to 40-43° C. and cooling to room temperature.
- S3, sampling and inspecting the prepared finished products mentioned above, and discharging and storing after passing the inspection.
- The present invention has the following advantages:
-
- (1) For the hair growth essence and its preparation method covered by the present invention, the components are safe and non-toxic, the formulation is reasonable, containing effective ingredients such as PEG-400, citrulline, biotin tripeptide-1, blue copper peptide and zinc gluconate; it can effectively strengthen hair roots, regulate metabolism and promote new hair growth, while the main ingredient PEG-400 has a dispersivity effect; blue copper peptide has the effect of improving skin repair ability, promoting skin absorption, deep skin wake-up and so on.
- (2) All components of the present invention are natural environment-friendly, mild and have no side effects on human body, and can effectively improve hair loss prevention rate and hair growth promotion rate.
- The following is a detailed description of the present invention in conjunction with specific examples. It should be noted that the following examples are only further descriptions of the present invention, but the scope of protection of the present invention is not limited to the following examples.
- The present example relates to a hair growth essence, including the following weight percentages of each component:
-
Water 89.24%, PEG-400 7%, Dextran 1%, Citrulline 0.5%, MSM 1%, biotin tripeptide-1 0.01%, blue copper peptide 0.35%, panthenol 0.5%, zinc gluconate 0.1%, phenoxyethanol 0.15%, chlorphenesin 0.15%. - The present invention also relates to the aforementioned preparation method of the hair growth essence, including the following steps:
-
- S1, accurately weighing the component materials of the formulation ingredient in proportion to each other, while cleaning the production equipment;
- S2, adding water to the stirring pot, increasing the temperature to 80-83° C., stirring evenly, holding for 20 minutes until completely dissolved, decreasing the temperature to 40-43° C. and cooling to room temperature.
- S3, sampling and inspecting the prepared finished products mentioned above, and discharging and storing after passing the inspection.
- The present invention has the following advantages:
-
- (1) For the hair growth essence and its preparation method covered by the present invention, the components are safe and non-toxic, the formulation is reasonable, containing effective ingredients such as PEG-400, citrulline, biotin tripeptide-1, blue copper peptide and zinc gluconate; it can effectively strengthen hair roots, regulate metabolism and promote new hair growth, while the main ingredient PEG-400 has a dispersivity effect; blue copper peptide has the effect of improving skin repair ability, promoting skin absorption, deep skin wake-up and so on.
- (2) All components of the present invention are natural environment-friendly, mild and have no side effects on human body, and can effectively improve hair loss prevention rate and hair growth promotion rate.
- The preparation process is basically the same as that of example 1, the only difference is the absence of PEG-400, blue copper peptide, panthenol and zinc gluconate in the raw materials used to prepare the hair growth essence.
- The preparation process is basically the same as that of example 1, the only difference is the absence of PEG-400, biotin tripeptide-1, panthenol and zinc gluconate in the raw materials used to prepare the hair growth essence.
- The preparation process is basically the same as that of example 1, the only difference is the absence of PEG-400, biotin tripeptide-1 and blue copper peptide in the raw materials used to prepare the hair growth essence.
- The effect of example 1 is compared with the effect of comparison example 1-3, see Table 1.
-
TABLE 1 Comparison Comparison Comparison Example 1 Example 1 Example 2 Example 3 Hair Growth 4.6 3.4 3.2 3.6 Promotion Rate Hair Loss 4.7 3.2 3.1 3.2 Prevention Rate - As shown by the data of example 1 and comparison example 1-3, PEG-400, biotin tripeptide-1, blue copper peptide, panthenol and zinc gluconate act synergistically during the use of the hair growth essence, synergistically increasing hair loss prevention rate and hair growth promotion rate.
- The specific examples of the present invention are described above. It should be understood that the present invention is not limited to the above specific embodiments, and the person skilled in the art may make various variations or modifications within the scope of the claims, which does not affect the essence of the present invention.
Claims (2)
1. A hair growth essence, characterized in that, comprising the following weight percentages of each component:
2. A preparation method of the hair growth essence according to claim 1 , characterized in that, comprising the following steps:
S1, accurately weighing the component materials of the formulation ingredient in proportion to each other, while cleaning the production equipment;
S2, adding water to the stirring pot, increasing the temperature to 80-83° C., stirring evenly, holding for 20 minutes until completely dissolved, decreasing the temperature to 40-43° C. and cooling to room temperature.
S3, sampling and inspecting the prepared finished products mentioned above, discharging and storing after passing the inspection.
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