US20150114855A1 - Hydrophilic iol packaging system - Google Patents

Hydrophilic iol packaging system Download PDF

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Publication number
US20150114855A1
US20150114855A1 US14/292,322 US201414292322A US2015114855A1 US 20150114855 A1 US20150114855 A1 US 20150114855A1 US 201414292322 A US201414292322 A US 201414292322A US 2015114855 A1 US2015114855 A1 US 2015114855A1
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US
United States
Prior art keywords
water
combination
container
water reservoir
pouch
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
US14/292,322
Other languages
English (en)
Inventor
Robert E. Glick
Stephen Q. Zhou
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aaren Scientific Inc
Original Assignee
Aaren Scientific Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aaren Scientific Inc filed Critical Aaren Scientific Inc
Priority to US14/292,322 priority Critical patent/US20150114855A1/en
Assigned to AAREN SCIENTIFIC INC. reassignment AAREN SCIENTIFIC INC. ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: GLICK, ROBERT E., ZHOU, STEPHEN Q.
Priority to KR1020167010967A priority patent/KR102284033B1/ko
Priority to CN201490001117.5U priority patent/CN206285172U/zh
Priority to EP14856145.9A priority patent/EP3060168B1/de
Priority to AU2014340186A priority patent/AU2014340186B2/en
Priority to PCT/US2014/061701 priority patent/WO2015061401A1/en
Priority to JP2016520136A priority patent/JP6470271B2/ja
Priority to EP15722813.1A priority patent/EP3148900A1/de
Priority to US14/693,060 priority patent/US9795474B2/en
Priority to PCT/US2015/027130 priority patent/WO2015183432A1/en
Publication of US20150114855A1 publication Critical patent/US20150114855A1/en
Priority to US15/179,915 priority patent/US10299914B2/en
Abandoned legal-status Critical Current

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Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D85/00—Containers, packaging elements or packages, specially adapted for particular articles or materials
    • B65D85/54—Containers, packaging elements or packages, specially adapted for particular articles or materials for articles of special shape not otherwise provided for
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02—Prostheses implantable into the body
    • A61F2/14—Eye parts, e.g. lenses, corneal implants; Implanting instruments specially adapted therefor; Artificial eyes
    • A61F2/16—Intraocular lenses
    • A61F2/1691—Packages or dispensers for intraocular lenses
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D1/00—Containers having bodies formed in one piece, e.g. by casting metallic material, by moulding plastics, by blowing vitreous material, by throwing ceramic material, by moulding pulped fibrous material, by deep-drawing operations performed on sheet material
    • B65D1/34—Trays or like shallow containers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D43/00—Lids or covers for rigid or semi-rigid containers
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D77/00—Packages formed by enclosing articles or materials in preformed containers, e.g. boxes, cartons, sacks or bags
    • B65D77/04—Articles or materials enclosed in two or more containers disposed one within another
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D81/00—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
    • B65D81/18—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents providing specific environment for contents, e.g. temperature above or below ambient
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D81/00—Containers, packaging elements, or packages, for contents presenting particular transport or storage problems, or adapted to be used for non-packaging purposes after removal of contents
    • B65D81/24—Adaptations for preventing deterioration or decay of contents; Applications to the container or packaging material of food preservatives, fungicides, pesticides or animal repellants
    • B65D81/26—Adaptations for preventing deterioration or decay of contents; Applications to the container or packaging material of food preservatives, fungicides, pesticides or animal repellants with provision for draining away, or absorbing, or removing by ventilation, fluids, e.g. exuded by contents; Applications of corrosion inhibitors or desiccators
    • B65D81/264—Adaptations for preventing deterioration or decay of contents; Applications to the container or packaging material of food preservatives, fungicides, pesticides or animal repellants with provision for draining away, or absorbing, or removing by ventilation, fluids, e.g. exuded by contents; Applications of corrosion inhibitors or desiccators for absorbing liquids
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B65—CONVEYING; PACKING; STORING; HANDLING THIN OR FILAMENTARY MATERIAL
    • B65D—CONTAINERS FOR STORAGE OR TRANSPORT OF ARTICLES OR MATERIALS, e.g. BAGS, BARRELS, BOTTLES, BOXES, CANS, CARTONS, CRATES, DRUMS, JARS, TANKS, HOPPERS, FORWARDING CONTAINERS; ACCESSORIES, CLOSURES, OR FITTINGS THEREFOR; PACKAGING ELEMENTS; PACKAGES
    • B65D2585/00—Containers, packaging elements or packages specially adapted for particular articles or materials
    • B65D2585/54—Containers, packaging elements or packages specially adapted for particular articles or materials for articles of special shape not otherwise provided for
    • B65D2585/545—Contact lenses

Definitions

  • This invention relates generally to packaging methods and systems, and more specifically to packaging methods and systems for foldable intraocular lenses.
  • IOL polymers can be broadly categorized into two groups: (1) materials that absorb less than 1 percent water and (2) materials that absorb more than 1 percent water. Materials that absorb less than one percent water are typically referred as hydrophobic polymers. Hydrophobic polymers may be foldable at room temperature. Their “foldability” results from their composition rather than from water acting as a plasticizer. Water absorbing polymers are typically referred to as hydrophilic polymers or hydrogels. The most common materials in this group have approximately 25 percent water by weight. Hydrophilic polymers are usually foldable at room temperature by virtue of absorbed water acting as a plasticizer.
  • IOL intraocular lens
  • normal saline 0.9 percent sodium chloride
  • Such lenses may reside in saline for up to five years prior to implantation.
  • the normal saline, in which these lenses are packaged is generally designed to mimic the conditions of the anterior segment of the eye where the lens will reside following implantation. This means that lenses will have similar dimension and mechanical characteristics in the eye as they have in the package where they reside prior to implantation.
  • Immersion in water or saline in the presence of other plastics needed for retention or insertion of the IOL can result in contamination of the IOL by chemical entities contained in or produced by other plastic components in the packaging system. Being immersed in water or saline, the IOL can “communicate” with plastic components via the liquid phase. Also, when an insertion instrument is removed from the package for use, water can flow from where the instrument was stored within the package to the IOL.
  • the packaging of IOL' s in water or saline has the additional disadvantage, especially when the IOL is packaged with an insertion instrument, of increasing the weight of the package, thereby increasing shipping costs.
  • the invention avoids the aforementioned problems in the prior art.
  • the invention is a method of maintaining a hydrophilic intraocular lens in a foldable state without immersing the intraocular lens in liquid water.
  • the method comprises the step of storing the foldable intraocular lens within a substantially air tight package containing a water reservoir not in direct contact with the lens.
  • the invention is a combination comprising: (a) a substantially air tight container having a water reservoir; and (b) a foldable hydrophilic intraocular lens disposed within the container so as not to be in direct contact with the water reservoir.
  • FIG. 1 is an upper side perspective view of a container usable in the invention
  • FIG. 2 is a lower side perspective view of the container illustrated in FIG. 1 ;
  • FIG. 3 is a bottom view of the container illustrated in FIG. 1 ;
  • FIG. 4 is a side view of the container illustrated in FIG. 1 ;
  • FIG. 5 is an end view of the container illustrated in FIG. 1 ;
  • FIG. 6 is a top view of the container illustrated in FIG. 1 , showing retention of an IOL and an IOL injector;
  • FIG. 7 is an exploded perspective view of a combination having features of the invention.
  • FIG. 8 is a cross-sectional detail view of a first distribution enhancer usable in the embodiment illustrated in FIG. 7 ;
  • FIG. 9 is a cross-sectional detail view of a second distribution enhancer usable in the embodiment illustrated in FIG. 7 ;
  • FIG. 10 is a cross-sectional detail view of a third distribution enhancer usable in the embodiment illustrated in FIG. 7 ;
  • FIG. 11 is a cross-sectional detail view of a fourth distribution enhancer usable in the embodiment illustrated in FIG. 7 ;
  • FIG. 12 is a perspective view of the embodiment illustrated in FIG. 7 disposed within a foil pouch.
  • the invention is a method of maintaining a hydrophilic intraocular lens in a foldable state without immersing the intraocular lens in liquid water.
  • the method comprises the step of storing the foldable intraocular lens within a substantially air tight package containing a water reservoir not in direct contact with the lens.
  • the word “foldable” means sufficiently pliable to allow the lens to be rolled into a cylinder with an external diameter sufficiently small to permit the lens to be injected into the eye of a patient through an injection tube having a diameter of 2 mm or less.
  • the phrase “not to be in direct contact with the lens” means that the water reservoir does not immerse more than the outer edges of the intraocular lens.
  • the inventors have discovered the surprising fact that sufficient hydration of a hydrophilic lens can be maintained to the extent needed for folding and insertion into an eye without immersion of the lens in a liquid.
  • this is accomplished by packaging the IOL with water saturated air, or nearly saturated air.
  • Nearly saturated it is meant a humidity level of at least about 90%, preferably at least 95%.
  • saturated such air cannot accept water from a hydrophilic IOL, and when nearly saturated, such air can only accept a minimal amount of water from a hydrophilic IOL.
  • the air within the container is nearly saturated and the volume of such air within the container is minimal (e.g. less than 100 cubic centimeters), the loss of water from the IOL is unimportantly small.
  • the invention is a combination 10 comprising: (a) a substantially air tight container 12 having a water reservoir 14 ; and (b) a foldable hydrophilic intraocular lens 16 disposed within the container 12 so as not to be in direct contact with the water reservoir 14 .
  • a substantially air tight container 12 having a water reservoir 14
  • a foldable hydrophilic intraocular lens 16 disposed within the container 12 so as not to be in direct contact with the water reservoir 14 .
  • FIGS. 1-5 illustrate a substantially air tight container 12 useable in the invention.
  • substantially air tight it is meant that the container 12 is fully enclosed, but very small amounts of air may diffuse through the container walls.
  • the container 12 comprises a tray 18 having an elongate compartment 20 bounded by a bottom wall 22 , side walls 26 and an elongate top opening 28 .
  • the tray 18 can has a length of about 7.8 inches, a width of about 2.75 inches and a maximum depth of about 1.0 inches.
  • the tray 18 can be made from a thermoplastic, such as polypropylene. In the embodiment illustrated in FIGS. 1-5 , the tray 18 can be made from 0.040′′ polypropylene.
  • the tray 18 has a circumferential rim 30 with a raised outer lip 32 surrounding a recessed inner band 34 .
  • the elongate top opening 28 is sealed by a cover 36 .
  • the cover 36 of the container 12 is typically provided by a foil lid 38 , preferably by a multilayered foil lid 38 , to minimize the amount of water lost to diffusion.
  • the water reservoir 14 provides an amount of water which barely exceeds that needed to moisture saturate the interior volume of the container 12 at temperatures up to those needed for steam sterilization, as well as to form small water droplets throughout the container 12 . This amount of water should include that which would be lost over the storage duration due to diffusion through the walls of the container 12 .
  • the amount of free water within the container will range from 0.5 to 3 milliliters of water, such as, for example, about 1 milliliter.
  • the water reservoir 14 can be provided by a variety of one or more devices.
  • the water reservoir 14 comprises water retained within a water permeable pouch 40 disposed below the cover 36 .
  • the pouch 40 is designed to capture and retain water which is only released as “free” water when atmospheric and other free water within the container 12 is depleted over time by diffusion through the container walls 22 and 24 .
  • the amount of water captured and retained within the pouch 40 when the container 12 is initially sealed is between about 5 milliliters and about 20 milliliters.
  • the pouch 40 can be made, for example, from a Tyvek, a material sold by E. I. du Pont de Nemours and Company of Wilmington, Del.
  • the pouch 40 effectively minimizes humidity variations throughout the container 12 .
  • the pouch 40 may contain distribution enhancers that facilitate distribution of water over the length and width of the pouch 40 regardless of the container's orientation.
  • the distribution enhancers can be provided by a towel 42 with wicking or sponge like properties, such as illustrated in FIG. 9 .
  • the distribution enhancers can also be provided by a piece of plastic 44 that has openings 46 in the form of blind holes (holes defined in one side of the material which do not extend through the material and out the opposite side) that span the surfaces of the tray 18 .
  • the blind holes are capable of retaining free water to saturate the vapor phase within the container 12 .
  • the distribution enhancers can also be provided by a water absorbing polymer 48 , such as polyvinyl pyrollidone or polymethacrylic acid, having a high water content that can be released to the atmosphere of the container 12 .
  • the water absorbing polymer 48 defines holes 50 , such as blind holes or through holes in which free water can reside.
  • the water reservoir 14 can also be provided by void volumes 52 within the container 12 .
  • the void volumes 52 are defined separate from the location within the container 12 of the intraocular lens 16 .
  • the void volumes 52 are maximized within the container 12 to minimize the potential for humidity gradients within the container 12 .
  • the water reservoir 14 can also be provided by blind holes 54 in interior surfaces of the tray walls 22 and/or 26 where small quantities of free water can reside.
  • the blind holes 54 span a majority of the length and width of the tray.
  • the water reservoir can also be provided by a non-smooth texture 56 on the interior of surfaces of the tray walls 22 and/or 26 capable of retaining small amounts of free water.
  • the combination 10 is preferably autoclavable—able to withstand being heated to 121 degrees C. or more for period of a half hour or more.
  • the combination 10 can be further sealed within an autoclavable foil pouch 58 .
  • Such autoclavable foil pouch 58 minimizes the amount of water lost to diffusion, provides a second sterile barrier and allows the container 12 to be introduced into a sterile field.
  • the intraocular lens 16 can be disposed unfolded within an injector 60 , wherein the injector 60 is adapted to fold and inject the intraocular lens 16 into the eye of a patient through a cylindrical injection tube 62 having an inside diameter sufficiently small to allow for surgical implanting of the lens with minimum trauma to the eye.
  • the cylindrical injection tube 62 has a diameter of 2 millimeters or less.

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  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Mechanical Engineering (AREA)
  • Ophthalmology & Optometry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Transplantation (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Food Science & Technology (AREA)
  • Ceramic Engineering (AREA)
  • Packages (AREA)
  • Prostheses (AREA)
  • Medicinal Preparation (AREA)
US14/292,322 2013-10-24 2014-05-30 Hydrophilic iol packaging system Abandoned US20150114855A1 (en)

Priority Applications (11)

Application Number Priority Date Filing Date Title
US14/292,322 US20150114855A1 (en) 2013-10-24 2014-05-30 Hydrophilic iol packaging system
JP2016520136A JP6470271B2 (ja) 2013-10-24 2014-10-22 親水性ｉｏｌ包装システム
AU2014340186A AU2014340186B2 (en) 2013-10-24 2014-10-22 Hydrophilic IOL packaging system
CN201490001117.5U CN206285172U (zh) 2013-10-24 2014-10-22 亲水iol包装系统及包含亲水iol包装系统的组合
EP14856145.9A EP3060168B1 (de) 2013-10-24 2014-10-22 Verpackungssystem für hydrophiles iol
KR1020167010967A KR102284033B1 (ko) 2013-10-24 2014-10-22 친수성의 iol 패키징 시스템
PCT/US2014/061701 WO2015061401A1 (en) 2013-10-24 2014-10-22 Hydrophilic iol packaging system
EP15722813.1A EP3148900A1 (de) 2014-05-30 2015-04-22 Verpackungssystem für hydrophiles iol
US14/693,060 US9795474B2 (en) 2013-10-24 2015-04-22 Hydrophilic IOL packaging system
PCT/US2015/027130 WO2015183432A1 (en) 2014-05-30 2015-04-22 Hydrophilic iol packaging system
US15/179,915 US10299914B2 (en) 2013-10-24 2016-06-10 Hydrophilic IOL packaging system

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201361895184P 2013-10-24 2013-10-24
US14/292,322 US20150114855A1 (en) 2013-10-24 2014-05-30 Hydrophilic iol packaging system

Related Child Applications (2)

Application Number Title Priority Date Filing Date
US14/693,060 Continuation-In-Part US9795474B2 (en) 2013-10-24 2015-04-22 Hydrophilic IOL packaging system
US15/179,915 Division US10299914B2 (en) 2013-10-24 2016-06-10 Hydrophilic IOL packaging system

Publications (1)

Publication Number Publication Date
US20150114855A1 true US20150114855A1 (en) 2015-04-30

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Family Applications (2)

Application Number Title Priority Date Filing Date
US14/292,322 Abandoned US20150114855A1 (en) 2013-10-24 2014-05-30 Hydrophilic iol packaging system
US15/179,915 Active 2035-06-12 US10299914B2 (en) 2013-10-24 2016-06-10 Hydrophilic IOL packaging system

Family Applications After (1)

Application Number Title Priority Date Filing Date
US15/179,915 Active 2035-06-12 US10299914B2 (en) 2013-10-24 2016-06-10 Hydrophilic IOL packaging system

Country Status (7)

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US (2) US20150114855A1 (de)
EP (1) EP3060168B1 (de)
JP (1) JP6470271B2 (de)
KR (1) KR102284033B1 (de)
CN (1) CN206285172U (de)
AU (1) AU2014340186B2 (de)
WO (1) WO2015061401A1 (de)

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US20170008686A1 (en) * 2014-03-28 2017-01-12 Terumo Kabushiki Kaisha Packaged medicine-filled container
US10299914B2 (en) 2013-10-24 2019-05-28 Carl Zeiss Meditec Production, LLC Hydrophilic IOL packaging system
USD849539S1 (en) * 2018-01-26 2019-05-28 Rai Strategic Holdings, Inc. Packaging tray
USD862230S1 (en) * 2017-09-19 2019-10-08 R.J. Reynolds Tobacco Company Dual packaging tray
USD862231S1 (en) * 2017-09-19 2019-10-08 R.J. Reynolds Tobacco Company Dual packaging tray
USD863965S1 (en) * 2017-01-04 2019-10-22 United States Postal Service Shipping box insert
USD867886S1 (en) * 2017-09-19 2019-11-26 R.J. Reynolds Tobacco Company Dual packaging tray
USD877613S1 (en) * 2018-12-21 2020-03-10 Sun Hydraulics, Llc Clamshell package for a cartridge valve
USD895145S1 (en) 2018-10-11 2020-09-01 Millennium Pharmaceuticals, Inc. Package for medical device
USD903507S1 (en) * 2019-01-18 2020-12-01 Gc Corporation Packaging case
USD915190S1 (en) * 2019-12-17 2021-04-06 Taiwan Fu Hsing Industrial Co., Ltd. Lock package
US20210259828A1 (en) * 2016-07-18 2021-08-26 Alcon Inc. Defined removal site on sterile blister pack
USD961376S1 (en) * 2020-07-29 2022-08-23 Regeneron Pharmaceuticals, Inc. Packaging
USD961377S1 (en) * 2020-07-29 2022-08-23 Regeneron Pharmaceuticals, Inc. Packaging
WO2023011886A1 (de) * 2021-08-02 2023-02-09 Carl Zeiss Meditec Ag Behältervorrichtung mit einem eine intraokularlinse aufweisenden ophthalmologischen injektor
US11793926B2 (en) 2019-07-29 2023-10-24 Regeneron Pharmaceuticals, Inc. Medical device packaging and related methods
USD1003707S1 (en) * 2022-03-10 2023-11-07 The Gillette Company Llc Razor package
USD1010437S1 (en) * 2021-12-13 2024-01-09 Becton, Dickinson And Company Packaging container for a medical injector
USD1035436S1 (en) 2022-08-26 2024-07-16 Regeneron Pharmaceuticals, Inc. Packaging
USD1042107S1 (en) 2022-08-26 2024-09-17 Regeneron Pharmaceuticals, Inc. Packaging
USD1047700S1 (en) 2022-08-26 2024-10-22 Regeneron Pharmaceuticals, Inc. Packaging

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US9795474B2 (en) 2013-10-24 2017-10-24 Carl Zeiss Meditec Ag Hydrophilic IOL packaging system
NL2012570B1 (nl) * 2014-04-04 2016-03-08 Sparkle Innovations B V Inrichting en werkwijze voor het druppel-voor-druppel toedienen van een vloeistof.
WO2015183432A1 (en) * 2014-05-30 2015-12-03 Aaren Scientific Inc. Hydrophilic iol packaging system
USD805400S1 (en) 2017-07-14 2017-12-19 Fivestar Gourmet Foods, Inc. Tray
USD804961S1 (en) 2017-07-14 2017-12-12 Fivestar Gourmet Foods, Inc. Tray
DE102017212498A1 (de) * 2017-07-20 2019-01-24 Robert Bosch Gmbh Kolbenpumpe, insbesondere Kraftstoff-Hochdruckpumpe für eine Brennkraftmaschine
CN108852558B (zh) * 2018-05-10 2021-01-15 辽宁美滋林药业有限公司 一种人工晶状体推注装置
CH716642A1 (de) * 2019-09-30 2021-03-31 Medicel Ag Intraokularlinsenpack für Versand und Lagerung von Intraokularlinsen.
CN117580548A (zh) * 2022-08-23 2024-02-20 哈尼塔镜片公司 用于疏水性人工晶状体的无菌湿润包装和包装方法
DE102022124667B3 (de) 2022-09-26 2024-03-21 Carl Zeiss Meditec Ag Aufnahmevorrichtung mit einem ophthalmologischen Injektor und einer Intraokularlinse

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US20160278915A1 (en) 2016-09-29
US10299914B2 (en) 2019-05-28
EP3060168B1 (de) 2024-08-07
KR102284033B1 (ko) 2021-08-02
JP6470271B2 (ja) 2019-02-13
JP2016533777A (ja) 2016-11-04
KR20160074516A (ko) 2016-06-28
EP3060168A4 (de) 2017-08-30
EP3060168A1 (de) 2016-08-31
WO2015061401A1 (en) 2015-04-30

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