US20140220012A1 - Novel VISTA-Ig constructs and the use of VISTA-Ig for Treatment of Autoimmune, Allergic and Inflammatory Disorders - Google Patents

Novel VISTA-Ig constructs and the use of VISTA-Ig for Treatment of Autoimmune, Allergic and Inflammatory Disorders Download PDF

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Publication number
US20140220012A1
US20140220012A1 US13/925,034 US201313925034A US2014220012A1 US 20140220012 A1 US20140220012 A1 US 20140220012A1 US 201313925034 A US201313925034 A US 201313925034A US 2014220012 A1 US2014220012 A1 US 2014220012A1
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United States
Prior art keywords
vista
cells
cell
fusion protein
protein
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US13/925,034
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Inventor
Randolph J. Noelle
Sabrina Ceeraz
Isabelle LeMercier
Elizabeth Nowak
Janet Lines
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Kings College London
Dartmouth College
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Kings College London
Dartmouth College
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Priority to US13/925,034 priority Critical patent/US20140220012A1/en
Assigned to THE TRUSTEES OF DARTMOUTH COLLEGE reassignment THE TRUSTEES OF DARTMOUTH COLLEGE ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: LEMERCIER, Isabelle, NOWAK, ELIZABETH
Assigned to KING'S COLLEGE LONDON, THE TRUSTEES OF DARTMOUTH COLLEGE reassignment KING'S COLLEGE LONDON ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: NOELLE, RANDOLPH J., CEERAZ, Sabrina
Assigned to KING'S COLLEGE LONDON reassignment KING'S COLLEGE LONDON ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: LINES, JANET
Publication of US20140220012A1 publication Critical patent/US20140220012A1/en
Priority to US15/131,691 priority patent/US20180051070A1/en
Assigned to NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT reassignment NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT CONFIRMATORY LICENSE (SEE DOCUMENT FOR DETAILS). Assignors: DARTMOUTH COLLEGE
Priority to US16/943,413 priority patent/US20210147521A1/en
Abandoned legal-status Critical Current

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US13/925,034 2012-06-22 2013-06-24 Novel VISTA-Ig constructs and the use of VISTA-Ig for Treatment of Autoimmune, Allergic and Inflammatory Disorders Abandoned US20140220012A1 (en)

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US15/131,691 US20180051070A1 (en) 2012-06-22 2016-04-18 Novel VISTA-Ig constructs and the use of VISTA-Ig for Treatment of Autoimmune, Allergic and Inflammatory Disorders
US16/943,413 US20210147521A1 (en) 2012-06-22 2020-07-30 Novel VISTA-Ig constructs and the use of VISTA-Ig for Treatment of Autoimmune, Allergic and Inflammatory Disorders

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US201261663431P 2012-06-22 2012-06-22
US201261663969P 2012-06-25 2012-06-25
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US201361776234P 2013-03-11 2013-03-11
US201361807135P 2013-04-01 2013-04-01
PCT/US2013/047009 WO2013192504A1 (en) 2012-06-22 2013-06-21 Novel vista-ig constructs and the use of vista-ig for treatment of autoimmune, allergic and inflammatory disorders
US13/925,034 US20140220012A1 (en) 2012-06-22 2013-06-24 Novel VISTA-Ig constructs and the use of VISTA-Ig for Treatment of Autoimmune, Allergic and Inflammatory Disorders

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US20140056892A1 (en) * 2010-03-26 2014-02-27 King's College London VISTA-Ig for Treatment of Autoimmune, Allergic and Inflammatory Disorders
WO2016196912A1 (en) * 2015-06-03 2016-12-08 Dana-Farber Cancer Institute, Inc. Methods to induce conversion of regulatory t cells into effector t cells for cancer immunotherapy
WO2017023753A1 (en) 2015-07-31 2017-02-09 University Of Florida Research Foundation, Inc. Hematopoietic stem cells in combinatorial therapy with immune checkpoint inhibitors against cancer
EP3270943A4 (en) * 2015-03-16 2018-10-17 Yissum Research Development Company of the Hebrew University of Jerusalem Ltd. Isolated peptides derived from the b7 ligand dimer interface and uses thereof
US10370455B2 (en) 2014-12-05 2019-08-06 Immunext, Inc. Identification of VSIG8 as the putative VISTA receptor (V-R) and use thereof to produce VISTA/VSIG8 agonists and antagonists
WO2019152810A1 (en) * 2018-02-02 2019-08-08 Bio-Techne Corporation Compounds that modulate the interaction of vista and vsig3 and methods of making and using
US10428145B2 (en) 2015-09-29 2019-10-01 Celgene Corporation PD-1 binding proteins and methods of use thereof
WO2020022782A1 (ko) * 2018-07-24 2020-01-30 주식회사 굳티셀 면역 관련 질환의 예방 또는 치료용 조성물
US10548957B2 (en) 2012-09-28 2020-02-04 Dana-Farber Cancer Institute, Inc. Targeted expansion of Qa-1-peptide-specific regulatory CD8 T cells to ameliorate arthritis
US10596195B2 (en) 2010-10-22 2020-03-24 Dana-Farber Cancer Institute, Inc. Discovery of regulatory T cells programmed to suppress an immune response
US10751414B2 (en) 2016-09-19 2020-08-25 Celgene Corporation Methods of treating psoriasis using PD-1 binding antibodies
US10766958B2 (en) 2016-09-19 2020-09-08 Celgene Corporation Methods of treating vitiligo using PD-1 binding antibodies
US10781254B2 (en) 2010-03-26 2020-09-22 The Trustees Of Dartmouth College VISTA regulatory T cell mediator protein, VISTA binding agents and use thereof
US10899836B2 (en) 2016-02-12 2021-01-26 Janssen Pharmaceutica Nv Method of identifying anti-VISTA antibodies
US10933115B2 (en) 2012-06-22 2021-03-02 The Trustees Of Dartmouth College VISTA antagonist and methods of use
US11009509B2 (en) 2015-06-24 2021-05-18 Janssen Pharmaceutica Nv Anti-VISTA antibodies and fragments
US11014987B2 (en) 2013-12-24 2021-05-25 Janssen Pharmaceutics Nv Anti-vista antibodies and fragments, uses thereof, and methods of identifying same
US11123426B2 (en) 2014-06-11 2021-09-21 The Trustees Of Dartmouth College Use of vista agonists and antagonists to suppress or enhance humoral immunity
US11180557B2 (en) 2012-06-22 2021-11-23 King's College London Vista modulators for diagnosis and treatment of cancer
US11242392B2 (en) 2013-12-24 2022-02-08 Janssen Pharmaceutica Nv Anti-vista antibodies and fragments
WO2022098846A1 (en) * 2020-11-04 2022-05-12 The Trustees Of Dartmouth College Vista agonist for treatment/prevention of ischemic and/or reperfusion injury
US11371989B2 (en) 2014-08-27 2022-06-28 Dana-Farber Cancer Institute, Inc. Intracellular osteopontin regulates the lineage commitment of lymphoid subsets
US11396647B2 (en) 2020-01-07 2022-07-26 Board Of Regents, The University Of Texas System Human methylthioadenosine/adenosine depleting enzyme variants for cancer therapy
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EP2864352A4 (en) 2016-05-25
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TWI705073B (zh) 2020-09-21
CN104619722B (zh) 2022-10-04
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FI3421486T3 (fi) 2023-12-15
HK1214272A1 (zh) 2016-07-22
TWI677507B (zh) 2019-11-21
TW201936643A (zh) 2019-09-16
US20180051070A1 (en) 2018-02-22
EP3421486A1 (en) 2019-01-02
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JP2018021049A (ja) 2018-02-08
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BR112014032276A2 (pt) 2017-11-28
CA2877533A1 (en) 2013-12-27
JP6665139B2 (ja) 2020-03-13
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WO2013192504A1 (en) 2013-12-27
US20210147521A1 (en) 2021-05-20

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