US20100086419A1 - Membrane Suction Pump Unit - Google Patents

Membrane Suction Pump Unit Download PDF

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Publication number
US20100086419A1
US20100086419A1 US12/530,996 US53099608A US2010086419A1 US 20100086419 A1 US20100086419 A1 US 20100086419A1 US 53099608 A US53099608 A US 53099608A US 2010086419 A1 US2010086419 A1 US 2010086419A1
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US
United States
Prior art keywords
membrane
cover
frame
suction pump
pump unit
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
US12/530,996
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English (en)
Inventor
Christoph Rebsamen
Marcel Felber
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Medela Holding AG
Original Assignee
Medela Holding AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Medela Holding AG filed Critical Medela Holding AG
Assigned to MEDELA HOLDING AG reassignment MEDELA HOLDING AG ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: FELBER, MARCEL, REBSAMEN, CHRISTOPH
Publication of US20100086419A1 publication Critical patent/US20100086419A1/en
Abandoned legal-status Critical Current

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Classifications

    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B45/00—Pumps or pumping installations having flexible working members and specially adapted for elastic fluids
    • F04B45/04—Pumps or pumping installations having flexible working members and specially adapted for elastic fluids having plate-like flexible members, e.g. diaphragms
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B45/00—Pumps or pumping installations having flexible working members and specially adapted for elastic fluids
    • F04B45/04—Pumps or pumping installations having flexible working members and specially adapted for elastic fluids having plate-like flexible members, e.g. diaphragms
    • F04B45/047—Pumps having electric drive
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/06—Milking pumps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/80—Suction pumps
    • A61M1/82—Membrane pumps, e.g. bulbs
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B49/00—Control, e.g. of pump delivery, or pump pressure of, or safety measures for, machines, pumps, or pumping installations, not otherwise provided for, or of interest apart from, groups F04B1/00 - F04B47/00
    • F04B49/02—Stopping, starting, unloading or idling control
    • F04B49/03—Stopping, starting, unloading or idling control by means of valves
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B53/00—Component parts, details or accessories not provided for in, or of interest apart from, groups F04B1/00 - F04B23/00 or F04B39/00 - F04B47/00
    • F04B53/10—Valves; Arrangement of valves
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F04—POSITIVE - DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS FOR LIQUIDS OR ELASTIC FLUIDS
    • F04B—POSITIVE-DISPLACEMENT MACHINES FOR LIQUIDS; PUMPS
    • F04B53/00—Component parts, details or accessories not provided for in, or of interest apart from, groups F04B1/00 - F04B23/00 or F04B39/00 - F04B47/00
    • F04B53/14—Pistons, piston-rods or piston-rod connections
    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F05—INDEXING SCHEMES RELATING TO ENGINES OR PUMPS IN VARIOUS SUBCLASSES OF CLASSES F01-F04
    • F05B—INDEXING SCHEME RELATING TO WIND, SPRING, WEIGHT, INERTIA OR LIKE MOTORS, TO MACHINES OR ENGINES FOR LIQUIDS COVERED BY SUBCLASSES F03B, F03D AND F03G
    • F05B2210/00—Working fluid
    • F05B2210/10—Kind or type
    • F05B2210/12—Kind or type gaseous, i.e. compressible
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S417/00—Pumps

Definitions

  • the invention relates to a membrane suction pump unit according to the preamble of claim 1 .
  • a generic membrane pump unit as part of a breast pump is known for example from U.S. Pat. No. 4,964,851.
  • the breast pump has an electromotor, a piston rod powered by the motor, and a connected pump membrane.
  • the pump membrane is held in a membrane frame and together with a membrane cover forms a pump chamber.
  • the membrane frame, pump membrane and membrane cover are connected to one another by means of a press connection, with three pins of the membrane frame being held frictionally engaged in corresponding openings in the membrane cover.
  • U.S. Pat. No. 7,070,400 also discloses the same type of membrane pump unit of a suction pump, where the membrane has a membrane piston with rear depressions.
  • the membrane cover defines a space with a flat floor section and a circular side wall widening conically outwards. This space is covered by the membrane piston and forms the pump chamber.
  • EP 0 744 180 likewise describes a membrane suction pump which now however is suited for simultaneous use of two suction connectors.
  • WO 2006/032156 also shows a membrane pump with three housing parts which are interconnected by snap elements.
  • the inventive membrane suction pump unit has a dimensionally stable membrane frame, a dimensionally stable monobloc membrane cover, which has a pump chamber with a floor region and a side wall encircling the floor region and widening outwards away from the floor region, and with a monobloc pump membrane which has a membrane plate, a flexible membrane piston, at least one inlet valve flap and at least one outlet valve flap, and a monobloc pump membrane with a membrane plate, a flexible membrane piston and with at least one inlet valve flap and at least one outlet valve flap, the membrane plate being arranged between the membrane frame and the membrane cover, and membrane frame, pump membrane and membrane cover being connected to one another by means of connecting elements in a preset position.
  • the membrane piston passes through the membrane frame and, together with the membrane cover, it forms a pump chamber or covers the pump chamber. According to the invention, there are more than three connecting elements, forming a material and/or positive fit.
  • the connecting elements connect the membrane frame and the membrane cover with each other and the pump membrane is hold between membrane frame and membrane cover.
  • the connecting elements can penetrate the pump membrane or the pump membrane can be hold between them.
  • connection cannot be broken automatically or by vibrations.
  • the connection between the individual parts i.e. frame, membrane and cover, to be broken, in particular if the pump triggers vibrations in the range of the natural oscillation of the device.
  • Assembly is also simplified. Assembly is usually carried out manually. This proves easier in practice if there are several connecting elements and thus positions than when three corresponding positions have to be manually brought into alignment. The danger of jamming is hereby lessened.
  • connecting elements Although using more than three connecting elements would actually result in static uncertainty, it has been shown that improved overall dimensional stability is attained.
  • the result of using more than three, in particular from six to twelve, connecting elements is thus greater stability and overall rigidity of the device.
  • membrane cover and membrane frame can distort less, and the unit exhibits increased tightness, or the danger of the unit becoming leaky due to fluctuations in temperature, vibrations or material fatigue is minimized.
  • nine connecting elements are used, which are distributed around the edge area.
  • the connecting means are preferably pins which are fixed in the seats. They can for example be bonded, welded or riveted. Positive locking elements, for example snap hooks, pine-tree snap locks and similar means, can also be used in place of pins, however.
  • the membrane cover has over its entire surface an approximately uniform thickness.
  • the inventive suction pump unit can be manufactured cost-effectively, in particular because it comprises only three parts, of which the two dimensionally stable parts, membrane frame and membrane cover, can be made from plastic in an injection moulding process, and the pump membrane can preferably be made from liquid silicone in an injection moulding process.
  • This suction pump unit is preferably used in breast pumps for expressing breast milk. However, it is also suitable for other suction pumps, for example drainage pumps.
  • FIG. 1 shows a perspective exploded view of the inventive membrane suction pump unit from above
  • FIG. 2 shows a perspective exploded view of the membrane suction pump unit as per FIG. 1 from below;
  • FIG. 3 shows a perspective illustration of the membrane frame
  • FIG. 4 shows a perspective illustration of the membrane cover in a second embodiment
  • FIG. 5 shows a perspective illustration of a fastening pin
  • FIG. 6 shows a membrane frame with electromotor in an exploded view
  • FIG. 7 shows a perspective exploded view of the membrane suction pump unit in a further embodiment.
  • the inventive membrane suction pump unit as per FIG. 1 has a membrane frame 1 , a pump membrane 2 and a membrane cover 3 . All these parts are preferably of monobloc design.
  • Membrane frame 1 and membrane cover 3 are dimensionally stable and preferably manufactured in an injection moulding process from plastic, for example thermoplastic, such as polyester.
  • the pump membrane 2 is also monobloc and made in an injection moulding process from liquid silicone.
  • the membrane frame 1 has a plane-parallel base plate 10 with a round through hole 11 .
  • a stop plate 16 Formed at one end of the base plate 10 and vertical thereto is a stop plate 16 .
  • This stop plate 16 has a pump unit seat 19 , in which a valve unit, not illustrated here, for example as disclosed in U.S. Pat. No. 4,964,851, is housed.
  • a suction opening 18 in the stop plate 16 which merges into an air intake 18 ′ on the rear side visible in FIG. 2 .
  • an electromotor 4 illustrated in FIG. 6 , which is connected to the later described piston connector 26 of the pump membrane via a piston rod, not illustrated.
  • the stop plate 16 is provided with an inlet opening 13 , pointing to the pump membrane 2 .
  • This inlet opening 13 is connected to the exterior via a connecting channel 13 ′′ and an inlet channel 13 ′ connected to the latter. This is shown in FIG. 3 .
  • the base plate 10 also has a channel 10 ′ on its surface, which channel terminates in the stop plate 16 in a through hole 10 ′′. This serves to assemble a vacuum adjustment pin, not illustrated here.
  • a first circular sealing groove 12 On the underside of the base plate 10 , evident in FIG. 2 , is a first circular sealing groove 12 . It encloses the through hole 11 , the inlet opening 13 and a groove forming an outlet channel 14 .
  • This outlet channel is arranged on the side of the through hole 11 diametrically opposite the inlet opening 13 and terminates on a side edge of the base plate 10 .
  • the base plate has an upper channel connection 17 in the form of a protruding nose having a U-shaped longitudinal section.
  • connecting elements are formed that project downwards to the pump membrane.
  • these connecting elements are substantially cylindrical pins 15 , 15 ′, 15 ′′, although other connecting elements such as snap lock elements can be present.
  • the snap lock elements are formed preferably on the outer edges of the base plate.
  • FIG. 7 Formed on the membrane frame 1 , on the circular front faces, are hooks 151 , and on the membrane cover 3 there are matching snap-in shackles 152 .
  • the pump membrane 2 needs no connecting elements, rather it is simply held clamped between membrane cover 3 and membrane frame 1 .
  • the pins 15 , 15 ′, 15 ′′ according to the first embodiment are arranged preferably exclusively in the edge region of the base plate 10 and outside the sealing groove 12 , distributed over the periphery. There are more than three pins 15 , 15 ′, 15 ′′. In the illustrated example there are nine pins, with preferably six to twelve pins being used.
  • all pins are configured the same length and same thickness.
  • pins of varying shape may also be used, as is the case here.
  • Some pins, preferably at least two opposing pins 15 ′′, are designed as positioning pins and have a basic cylindrical body and a tapering or tapered tip.
  • Some pins, here first pins 15 have a larger diameter than second pins 15 ′.
  • the pins 15 , 15 ′, 15 ′′ can also be equipped with vertical ribs 150 , as shown in FIG. 5 .
  • the length of the pins 15 , 15 ′, 15 ′′ is such that they pass through the pump membrane 2 arranged behind and project at least partially into the membrane cover 3 or likewise pass preferably completely through this and terminate at its opposite surface.
  • the pins are formed on the membrane cover or that some of the pins are arranged on the membrane frame and some on the membrane cover, as illustrated in FIG. 4 .
  • the pump membrane 2 arranged beneath the base plate 10 has a likewise substantially plane-parallel membrane plate 20 .
  • This membrane plate 20 has approximately the same base surface as the base plate 10 .
  • the latter merges into a membrane piston 21 , which projects upwards of the membrane plate 20 to the base plate 10 .
  • the membrane piston 21 is designed as a cap shape, and preferably has annular circular recesses.
  • Formed in the middle of the membrane piston 20 is the piston seat 26 in the form of a hollow cylinder. The piston can easily plug into this seat 26 and is held therein positively and non-positively.
  • a horseshoe-shaped inlet valve flap 23 Located on one side of the membrane piston 21 is a horseshoe-shaped inlet valve flap 23 .
  • the membrane plate 20 has two likewise substantially horseshoe-shaped outlet valve flaps 24 arranged at a distance apart. There can also be more than one or fewer than two valve flaps 23 , 24 .
  • the membrane plate 20 has an upper sealing lip 22 which, on the top side facing the base plate 10 , encloses the membrane piston 21 and the valve flaps 23 , 24 , and which is self-contained and projects upwards.
  • the membrane plate 20 similarly has on its underside facing the membrane cover 3 a circular lower sealing lip 28 , which likewise encloses membrane piston 21 and valve flaps 23 , 24 and projects downwards.
  • the two sealing lips 22 , 28 are preferably congruent.
  • sealing lips it is however also possible that only one of the two sealing lips is present, or that they are not congruent. Instead of the sealing lips, sealing grooves could also be in place, and the membrane cover and/or the membrane frame are provided with a corresponding sealing lip or edge.
  • a protruding nose 27 projecting over the edge, but otherwise flush with the top side and underside of the plate 20 .
  • first and second fastening holes 25 , 25 ′ the diameters of which preferably correspond to the associated pins 15 , 15 ′, 15 ′′ of the base plate 10 , or are slightly larger.
  • the membrane cover 3 has a cover plate 30 , the top side of which pointing to the pump membrane 2 is likewise designed substantially plane. Its underside on the other hand is structured as is described hereinbelow.
  • a pump chamber 31 Formed in the middle of the cover plate 30 is a pump chamber 31 , which has a floor region at the same level as the surface of the remaining cover plate 30 and a raised circular side wall 36 , the side wall being designed to incline upwards and outwards, so that the opening widens out over the floor region.
  • the side wall 36 can be designed straight oblique or, as shown here, curved.
  • the side wall 36 is penetrated by at least one inlet channel, here three inlet channels 33 ′ running parallel to one another. These channels 33 come from an inlet basin 33 , which is designed as a recess in the cover plate 30 and terminate in the floor region at a distance from the side wall 36 .
  • the side wall 36 is pierced by at least one, here two outlet channels 34 running radially outwards and terminating at a distance outside the side wall 36 in the cover plate 30 .
  • Pump chamber 31 , inlet basin 33 and both inlet and outlet channels 33 ′, 34 are enclosed by a fully circular second sealing groove 32 .
  • a protruding nose Formed at one side edge of the cover plate 30 is a protruding nose, which forms a lower channel connector 37 with upright side walls.
  • This lower channel connector 37 forms the counterpart to the upper channel connector 17 and thus preferably has a U-shaped longitudinal section.
  • the abovementioned protruding nose 27 of the pump membrane 2 is of such a size that it corresponds to the base area of the channel connectors 17 , 37 and is held therein.
  • the underside of the cover plate 30 is designed structured as a negative to the elements formed in the top side of the cover plate.
  • the recesses of the top side are designed extending downwards on the underside and the elevations of the top side are correspondingly sunk in the underside.
  • the cover plate 30 has a thickness approximately uniform over the entire base area or over a large part of the base area. This does not however apply at all points. By way of example, this does not apply in the area of the reinforcing links between the sockets or between other possible elevations in the underside.
  • This type of structured cover plate can also be employed in suction pump units whose connecting elements connect the individual parts frictionally engaged or non-positively.
  • the pump membrane 2 or its membrane plate 20 is now clamped in between the base plate 10 of the membrane frame 1 and the cover plate 30 of the membrane plate 3 .
  • the membrane piston 21 passes through the through hole 11 and because of the motor can move up and down.
  • the membrane piston 21 covers the pump chamber 31 and, since the outer diameter of the membrane piston 21 is the same size as or greater than the outer diameter of the side wall 36 of the pump chamber 31 , it seals the chamber 31 except for the inlet and outlet channels 33 ′, 34 .
  • the fastening pins 15 , 15 ′, 15 ′′ pass through the fastening holes 25 , 25 ′ of the pump membrane 2 and are plugged positively into the uptake sockets 35 , 35 ′, 35 ′′ of the membrane cover 3 .
  • they are stuck therein by means of adhesive or are connected otherwise to form a material or positive fit.
  • they can be ultrasound-welded, vibration-welded, welded at high frequency or ultrasound-riveted.
  • the inlet opening 13 lies above the inlet valve flap 23 and the latter lies above the inlet basin 33 .
  • the outlet channel 14 of the membrane frame 1 lies above the outlet valve flaps 24 and the latter lie above the outlet channels 34 of the membrane cover.
  • the upper and lower sealing lips 22 , 28 lie in the first and second sealing grooves 12 , 32 , respectively, and thus seal the areas in each case enclosed thereby to the exterior.
  • the side walls of the lower channel connector 37 resiliently enclose the side walls of the upper channel connector 17 and thus form a tight positive and frictional connection.
  • the nose 27 of the pump membrane 2 lies on the lower channel connector 37 .
  • the membrane piston 21 passes through the through hole 11 of the base plate 10 when the unit is in the assembled state.

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  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Mechanical Engineering (AREA)
  • General Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Vascular Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pediatric Medicine (AREA)
  • Reciprocating Pumps (AREA)
US12/530,996 2007-03-13 2008-03-04 Membrane Suction Pump Unit Abandoned US20100086419A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CH4052007 2007-03-13
CH405/07 2007-03-13
PCT/CH2008/000086 WO2008110022A2 (de) 2007-03-13 2008-03-04 Membransaugpumpenaggregat

Publications (1)

Publication Number Publication Date
US20100086419A1 true US20100086419A1 (en) 2010-04-08

Family

ID=38910890

Family Applications (1)

Application Number Title Priority Date Filing Date
US12/530,996 Abandoned US20100086419A1 (en) 2007-03-13 2008-03-04 Membrane Suction Pump Unit

Country Status (12)

Country Link
US (1) US20100086419A1 (ru)
EP (1) EP2129915A2 (ru)
JP (1) JP2010520962A (ru)
KR (1) KR20090118065A (ru)
CN (1) CN101636585B (ru)
AU (1) AU2008226308A1 (ru)
BR (1) BRPI0808211A2 (ru)
CA (1) CA2679865A1 (ru)
MX (1) MX2009009807A (ru)
RU (1) RU2472967C2 (ru)
TW (1) TW200900586A (ru)
WO (1) WO2008110022A2 (ru)

Cited By (1)

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US20150139821A1 (en) * 2013-11-15 2015-05-21 Invenix, Inc. Pump chamber including internal surface modifications

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CA2964674A1 (en) 2006-09-28 2008-03-28 Smith & Nephew, Inc. Portable wound therapy system
GB201015656D0 (en) 2010-09-20 2010-10-27 Smith & Nephew Pressure control apparatus
US9084845B2 (en) 2011-11-02 2015-07-21 Smith & Nephew Plc Reduced pressure therapy apparatuses and methods of using same
US9427505B2 (en) 2012-05-15 2016-08-30 Smith & Nephew Plc Negative pressure wound therapy apparatus
CN104712535B (zh) * 2014-11-05 2016-11-16 东莞市天昶机电制造有限公司 一种用于医用雾化器的消音压缩机
CN107249659B (zh) 2014-12-22 2021-03-16 史密夫及内修公开有限公司 负压伤口治疗装置和方法
JP2016200014A (ja) * 2015-04-07 2016-12-01 住友ゴム工業株式会社 ダイアフラムポンプ
CH711436A1 (de) * 2015-08-20 2017-02-28 Medmix Systems Ag Membranpumpe mit Medientrennung.
CN109611315B (zh) * 2019-01-25 2023-09-26 东莞市简爱母婴用品有限公司 泵阀一体化的真空泵及吸奶器

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US4168288A (en) * 1978-06-29 1979-09-18 Briggs & Stratton Corporation Combined carburetor and impulse fuel pump
US4303376A (en) * 1979-07-09 1981-12-01 Baxter Travenol Laboratories, Inc. Flow metering cassette and controller
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US4929229A (en) * 1988-11-30 1990-05-29 Isg/Ag Breastpump having improved valve mechanism
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* Cited by examiner, † Cited by third party
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US20150139821A1 (en) * 2013-11-15 2015-05-21 Invenix, Inc. Pump chamber including internal surface modifications
US10156231B2 (en) * 2013-11-15 2018-12-18 Ivenix, Inc. Pump chamber including internal surface modifications

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MX2009009807A (es) 2009-09-24
EP2129915A2 (de) 2009-12-09
RU2472967C2 (ru) 2013-01-20
RU2009136224A (ru) 2011-04-20
WO2008110022A2 (de) 2008-09-18
CA2679865A1 (en) 2008-09-18
KR20090118065A (ko) 2009-11-17
TW200900586A (en) 2009-01-01
CN101636585B (zh) 2012-02-22
WO2008110022A3 (de) 2008-11-06
AU2008226308A1 (en) 2008-09-18
CN101636585A (zh) 2010-01-27
BRPI0808211A2 (pt) 2014-07-01
JP2010520962A (ja) 2010-06-17

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