US20100038322A1 - Dialysis cassettes and related systems and methods - Google Patents

Dialysis cassettes and related systems and methods Download PDF

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Publication number
US20100038322A1
US20100038322A1 US12/542,971 US54297109A US2010038322A1 US 20100038322 A1 US20100038322 A1 US 20100038322A1 US 54297109 A US54297109 A US 54297109A US 2010038322 A1 US2010038322 A1 US 2010038322A1
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Prior art keywords
liquid
cassette
pump chamber
dialysis
temperature
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Abandoned
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US12/542,971
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English (en)
Inventor
Frank Hedmann
Stephan Klatte
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Fresenius Medical Care Deutschland GmbH
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Fresenius Medical Care Deutschland GmbH
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Filing date
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Assigned to FRESENIUS MEDICAL CARE DEUTSCHLAND GMBH reassignment FRESENIUS MEDICAL CARE DEUTSCHLAND GMBH ASSIGNMENT OF ASSIGNORS INTEREST (SEE DOCUMENT FOR DETAILS). Assignors: KLATTE, STEPHAN, HEDMANN, FRANK
Publication of US20100038322A1 publication Critical patent/US20100038322A1/en
Priority to US13/464,264 priority Critical patent/US8540886B2/en
Priority to US13/950,417 priority patent/US9302040B2/en
Abandoned legal-status Critical Current

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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/28—Peritoneal dialysis ; Other peritoneal treatment, e.g. oxygenation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/15—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with a cassette forming partially or totally the flow circuit for the treating fluid, e.g. the dialysate fluid circuit or the treating gas circuit
    • A61M1/152—Details related to the interface between cassette and machine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/15—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with a cassette forming partially or totally the flow circuit for the treating fluid, e.g. the dialysate fluid circuit or the treating gas circuit
    • A61M1/153—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with a cassette forming partially or totally the flow circuit for the treating fluid, e.g. the dialysate fluid circuit or the treating gas circuit the cassette being adapted for heating or cooling the treating fluid, e.g. the dialysate or the treating gas
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/15—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with a cassette forming partially or totally the flow circuit for the treating fluid, e.g. the dialysate fluid circuit or the treating gas circuit
    • A61M1/154—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with a cassette forming partially or totally the flow circuit for the treating fluid, e.g. the dialysate fluid circuit or the treating gas circuit with sensing means or components thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/15—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with a cassette forming partially or totally the flow circuit for the treating fluid, e.g. the dialysate fluid circuit or the treating gas circuit
    • A61M1/155—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with a cassette forming partially or totally the flow circuit for the treating fluid, e.g. the dialysate fluid circuit or the treating gas circuit with treatment-fluid pumping means or components thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/15—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with a cassette forming partially or totally the flow circuit for the treating fluid, e.g. the dialysate fluid circuit or the treating gas circuit
    • A61M1/156—Constructional details of the cassette, e.g. specific details on material or shape
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/15—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with a cassette forming partially or totally the flow circuit for the treating fluid, e.g. the dialysate fluid circuit or the treating gas circuit
    • A61M1/156—Constructional details of the cassette, e.g. specific details on material or shape
    • A61M1/1565—Details of valves
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1654—Dialysates therefor
    • A61M1/1656—Apparatus for preparing dialysates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/16—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with membranes
    • A61M1/1654—Dialysates therefor
    • A61M1/1656—Apparatus for preparing dialysates
    • A61M1/166—Heating
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/44—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for cooling or heating the devices or media
    • A61M5/445—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests having means for cooling or heating the devices or media the media being heated in the reservoir, e.g. warming bloodbags
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M1/00—Suction or pumping devices for medical purposes; Devices for carrying-off, for treatment of, or for carrying-over, body-liquids; Drainage systems
    • A61M1/14—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis
    • A61M1/15—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with a cassette forming partially or totally the flow circuit for the treating fluid, e.g. the dialysate fluid circuit or the treating gas circuit
    • A61M1/159—Dialysis systems; Artificial kidneys; Blood oxygenators ; Reciprocating systems for treatment of body fluids, e.g. single needle systems for hemofiltration or pheresis with a cassette forming partially or totally the flow circuit for the treating fluid, e.g. the dialysate fluid circuit or the treating gas circuit specially adapted for peritoneal dialysis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/12—General characteristics of the apparatus with interchangeable cassettes forming partially or totally the fluid circuit
    • A61M2205/127—General characteristics of the apparatus with interchangeable cassettes forming partially or totally the fluid circuit with provisions for heating or cooling
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/36—General characteristics of the apparatus related to heating or cooling
    • A61M2205/3606—General characteristics of the apparatus related to heating or cooling cooled
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2205/00—General characteristics of the apparatus
    • A61M2205/36—General characteristics of the apparatus related to heating or cooling
    • A61M2205/3626—General characteristics of the apparatus related to heating or cooling by controlled mixing of fluids at different temperatures

Definitions

  • This invention relates to dialysis cassettes and related systems and methods.
  • Cassettes for conveying dialysis liquids are known.
  • Some known cassettes include connection elements for the connection of solution bags and lines leading to a patient and to a dialysis machine.
  • the cassettes can have at least one pump chamber with an inflow and an outflow port as well as passages for conducting the supplied and conveyed liquid.
  • the passages can be closed by the application of a compressive force acting on the walls of the passages.
  • a heating device can be used for heating the dialysis liquid in the cassette to a desired temperature.
  • Such cassettes are used, for example, in the area of peritoneal dialysis.
  • the peritoneum is filled and emptied with the help of a dialysis machine called a “cycler.”
  • the flow of the dialysis liquid, i.e., dialysate is controlled by a cassette system.
  • the dialysate is heated to the desired temperature in the cassette and is subsequently infused into the peritoneum. If an unexpected stoppage of the cycler occurs and the liquid supply to the patient is interrupted, the dialysate is no longer circulated in the cassette. As a result, the dialysate may be heated above the desired temperature due to the inertia of the heating apparatus.
  • the overheated dialysate typically cannot be used for infusion into the patient when the cycler is restarted.
  • the dialysate is typically discarded and replaced with new dialysate before the peritoneal dialysis treatment resumes.
  • a cassette for conveying liquids, in particular dialysis liquids.
  • the cassette includes connection elements for the connection of solution bags and lines leading to a patient and/or to a dialysis machine.
  • the cassette further includes at least one pump chamber with an inflow port and an outflow port.
  • the cassette forms lines or passages for conducting the supplied and conveyed liquids through the cassette.
  • the cassette also includes valves for closing the lines.
  • a heating device is provided for heating the liquid present in the passages to a desired temperature (e.g., a preset desired temperature).
  • a control unit is also provided and is configured to conduct (e.g., circulate) liquid heated above the desired temperature until the desired temperature has been reached again.
  • At least one temperature sensor is provided for the measurement of the temperature of the liquid in the cassette.
  • the temperature sensor is positioned within the cassette.
  • the temperature sensor is located on a dialysis machine and cooperates with the cassette when the cassette is positioned in a cassette compartment of the dialysis machine.
  • two pump chambers are provided between which the liquid can be displaced until the liquid reaches (e.g., cools to) the desired temperature.
  • the heating device and a heating region of the cassette act as a continuous-flow heater.
  • the heating device and the heating region of the cassette are configured so that liquid is heated as it flows through the heating region of the cassette.
  • a method in another aspect of the invention, includes displacing a liquid between the two pump chambers of the cassette until the liquid reaches (e.g., cools to) a desired temperature.
  • the passage to which the line draining the liquid is connected is closed.
  • the heating power of the heating device is reduced.
  • the liquid is pumped through one of the pump chambers from a heating region of the cassette into the other pump chamber.
  • the resulting mixture of liquid i.e., the mixture of the overheated liquid and the cool liquid
  • the resulting mixture of liquid is conveyed in reverse operation through a heating region of the cassette into the other pump chamber in order to simultaneously cool the heating region of the cassette in this process.
  • the mixed liquid is conveyed in forward operation through the heating region of the cassette into the other pump chamber to distribute the excess heat in the cassette.
  • An additional aspect of the invention relates to a dialysis machine, such as a peritoneal dialysis machine, having a device for the reception of one of the previously described cassettes as well as a pump unit for actuating the pump chambers of the cassette.
  • the dialysis machine includes a heating device configured to heat liquid flowing through a heating region of the cassette and a control unit configured to conduct (e.g., circulate) liquid heated above a desired temperature until the desired temperature has been reached again.
  • a dialysis liquid that may have been overheated can advantageously be returned to a desired temperature without having to discard the liquid.
  • the total amount of dialysis liquid used during the treatment can be reduced because it is generally unnecessary to discard the overheated dialysis liquid and replace it with new dialysis liquid.
  • the amount of time required for the treatment can be reduced since it is generally unnecessary to drain the overheated dialysis liquid and then replace it with new dialysis liquid.
  • FIG. 1 is a plan view of a dialysis cassette.
  • FIG. 2 is a front view of a dialysis system including a dialysis machine and the dialysis cassette of FIG. 1 .
  • FIG. 3 is a front view of the dialysis machine of FIG. 2 with a door of the dialysis machine open to expose a cassette compartment of the dialysis machine.
  • FIG. 1 shows a disposable cassette 10 that can be retained in a correspondingly designed cassette compartment or mount of a dialysis machine (e.g., a peritoneal dialysis machine) 100 (shown in FIG. 2 ).
  • a dialysis machine e.g., a peritoneal dialysis machine
  • the reference numerals 2 , 4 , 6 characterize connection elements for the connection of solution bags, of lines leading to the patient and to the dialysis machine, and of drainage lines.
  • Two fixedly attached hoses or lines 104 and 106 are arranged at the connectors 4 and 6 , with one of the hoses representing the patient hose and the other representing the drainage hose.
  • the connection elements 2 allow the operator to connect the solution bags or other medication containers to the cassette 10 .
  • the cassette 10 includes a base body 12 that is made of plastic and can be manufactured using injection molding technology or deep-drawing technology. Cut-outs as well as passages extend in the base body 12 .
  • the base body 12 partly forms the walls of two pump chambers 20 , 22 arranged next to one another as well as liquid passageways 30 , 40 , 50 , 60 extending within the cassette 10 .
  • Liquid passageways 80 and 90 are likewise partly formed by the base body 12 between the pump chambers 20 and 22 .
  • the liquid passageway 50 is serpentine shaped and is provided within a heating region 52 of the cassette 10 .
  • One end of the passageway 50 is connected to the passageway 30 , and the other end of the passageway 50 is connected to the passageway 40 .
  • the cassette 10 is configured to be retained in a cassette compartment of the dialysis machine 100 .
  • the dialysis machine 100 includes a heating device 108 .
  • the heating device 108 is positioned adjacent the heating region 52 of the cassette 10 through which the passageway 50 extends.
  • the dialysis liquid (e.g., dialysate) flowing through the passageway 50 is heated when the cassette 10 is positioned within the cassette compartment of the dialysis machine 100 and the beating device 108 is activated.
  • the dialysis machine 100 includes two pumps 110 , 112 and multiple valve tappets T 1 , T 2 , T 3 , T 4 , T 5 , T 6 , T 7 , T 8 , T 9 , T 10 , T 11 , T 12 , T 13 , T 14 , T 15 , and T 16 .
  • the pumps 110 , 112 cooperate with the pump chambers 20 , 22 to pump liquid through the various passages of the cassette 10 .
  • valve tappets T 1 , T 2 , T 3 , T 4 , T 5 , T 6 , T 7 , T 8 , T 9 , T 10 , T 11 , T 12 , T 13 , T 14 , T 15 , and T 16 cooperate with corresponding valves V 1 , V 2 , V 3 , V 4 , V 5 , V 6 , V 7 , V 8 , V 9 , V 10 , V 11 , V 12 , V 13 , V 14 , V 15 and V 16 of the cassette 10 to direct the conveyed liquid through the cassette 10 in a desired manner.
  • valve tappets T 1 , T 2 , T 3 , T 4 , T 5 , T 6 , T 7 , T 8 , T 9 , T 10 , T 11 , T 12 , T 13 , T 14 , T 15 , and T 16 can be pneumatically, hydraulically and/or mechanically controlled.
  • liquid e.g., dialysate
  • the heating region 52 of the cassette 10 in the direction of the patient line that carries the liquid to the patient and that is connected to the connector 4 .
  • the liquid thus flows from the pump chamber 22 via the passageway 80 after the opening of the valve V 4 through the passageway 50 adjacent the heater 108 of the dialysis machine 100 and via the opened valve V 5 as well as the opened valve V 6 .
  • heat emitted from the heater 108 increases the temperature of the liquid.
  • the heater 108 and the heating region 52 of the cassette 10 together act as a continuous-flow heating mechanism.
  • the pump chamber 20 is supplied with fresh liquid.
  • the fresh liquid can, for example, be supplied to the pump chamber 20 via the opened valves V 11 and V 1 , while the valves V 7 , V 3 and V 2 as well as V 9 are simultaneously closed.
  • the liquid present in the passageway 50 can be overheated due to an overshooting of the heating regulator.
  • the overheated liquid can typically not be infused into the peritoneum due to its elevated temperature.
  • valve V 6 When overheating of the liquid in the passageway 50 occurs, the valve V 6 is closed and the heating power in the heater 108 of the dialysis machine 100 is reduced via a control unit that is arranged in the dialysis machine 100 . At the same time, the valve V 11 is closed to prevent any additional fresh solution from being delivered to the pump chamber 20 . After turning off the heater 108 and closing valves V 6 and V 11 , the overheated solution is pumped via the pump chamber 22 through the passageway 50 adjacent the continuous-flow heater and into the pump chamber 20 . To do this, the valve V 4 , the valve V 5 , the valve V 7 , and the valve V 1 are opened. The pump stroke of the pump chamber 22 is ended when the pump chamber 20 is filled or the pump chamber 22 is emptied.
  • the resulting mixed liquid which is comparatively cooler than the overheated liquid due to the mixing of the liquids, is conveyed via the passageway 50 adjacent the heater 108 into the pump chamber 22 in reverse operation.
  • the liquid is pumped back into the pump chamber 22 via the opened valve V 1 , the opened valve V 7 , the opened valve V 5 , and the opened valve V 4 .
  • the partially overheated heating region 52 of the cassette 10 is also cooled by the comparatively cooler liquid.
  • the mixture of liquid i.e., the mixture of the overheated liquid and any cool liquid that was present in the pump chamber 20 when the overheated liquid was delivered to the pump chamber 20
  • the liquid is conducted into the pump chamber 22 via the opened valve V 2 , the opened valve V 5 , the opened valve V 7 , and the opened valve V 3 .
  • the excess heat of the overheated liquid is distributed in the cassette so that the temperature of the overheated liquid can be lowered to the desired temperature.
  • the cassette itself includes a heater or part of a heater.
  • the heating region of the cassette can, for example, be equipped with a heating coil. In such cases, the heating coil can be connected to a power supply of the dialysis machine when the cassette is inserted into the cassette compartment in order to provide the coil with power that generates heat.
  • control unit has been described as being part of the dialysis machine 100 , the control unit can alternatively be located at any of various other locations outside of the cassette 10 .

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  • Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Urology & Nephrology (AREA)
  • Emergency Medicine (AREA)
  • Anesthesiology (AREA)
  • Engineering & Computer Science (AREA)
  • Vascular Medicine (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • External Artificial Organs (AREA)
US12/542,971 2008-08-18 2009-08-18 Dialysis cassettes and related systems and methods Abandoned US20100038322A1 (en)

Priority Applications (2)

Application Number Priority Date Filing Date Title
US13/464,264 US8540886B2 (en) 2008-08-18 2012-05-04 Dialysis cassettes and related systems and methods
US13/950,417 US9302040B2 (en) 2008-08-18 2013-07-25 Dialysis cassettes and related systems and methods

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE102008038097.0 2008-08-18
DE102008038097A DE102008038097A1 (de) 2008-08-18 2008-08-18 Kassette zur Förderung von Flüssigkeiten, insbesondere Dialyseflüssigkeiten

Related Child Applications (1)

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US13/464,264 Division US8540886B2 (en) 2008-08-18 2012-05-04 Dialysis cassettes and related systems and methods

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US20100038322A1 true US20100038322A1 (en) 2010-02-18

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US12/542,971 Abandoned US20100038322A1 (en) 2008-08-18 2009-08-18 Dialysis cassettes and related systems and methods
US13/464,264 Active US8540886B2 (en) 2008-08-18 2012-05-04 Dialysis cassettes and related systems and methods
US13/950,417 Active 2030-06-05 US9302040B2 (en) 2008-08-18 2013-07-25 Dialysis cassettes and related systems and methods

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US13/464,264 Active US8540886B2 (en) 2008-08-18 2012-05-04 Dialysis cassettes and related systems and methods
US13/950,417 Active 2030-06-05 US9302040B2 (en) 2008-08-18 2013-07-25 Dialysis cassettes and related systems and methods

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US (3) US20100038322A1 (zh)
EP (1) EP2313134B1 (zh)
JP (1) JP5587887B2 (zh)
CN (1) CN102123754B (zh)
DE (1) DE102008038097A1 (zh)
ES (1) ES2449866T3 (zh)
WO (1) WO2010020390A1 (zh)

Cited By (8)

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CN102123754B (zh) 2014-09-17
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JP5587887B2 (ja) 2014-09-10
US20130310736A1 (en) 2013-11-21
WO2010020390A1 (de) 2010-02-25
US20120220937A1 (en) 2012-08-30
EP2313134A1 (de) 2011-04-27
CN102123754A (zh) 2011-07-13
US9302040B2 (en) 2016-04-05
DE102008038097A1 (de) 2010-02-25
JP2012500070A (ja) 2012-01-05
EP2313134B1 (de) 2014-02-19

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