US20080287883A1 - Injection Device - Google Patents
Injection Device Download PDFInfo
- Publication number
- US20080287883A1 US20080287883A1 US11/791,397 US79139705A US2008287883A1 US 20080287883 A1 US20080287883 A1 US 20080287883A1 US 79139705 A US79139705 A US 79139705A US 2008287883 A1 US2008287883 A1 US 2008287883A1
- Authority
- US
- United States
- Prior art keywords
- dose
- thread
- sleeve
- injection device
- piston rod
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Abandoned
Links
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31545—Setting modes for dosing
- A61M5/31548—Mechanically operated dose setting member
- A61M5/3155—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe
- A61M5/31551—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe including axial movement of dose setting member
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31545—Setting modes for dosing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31525—Dosing
- A61M5/31528—Dosing by means of rotational movements, e.g. screw-thread mechanisms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31545—Setting modes for dosing
- A61M5/31548—Mechanically operated dose setting member
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31545—Setting modes for dosing
- A61M5/31548—Mechanically operated dose setting member
- A61M5/3155—Mechanically operated dose setting member by rotational movement of dose setting member, e.g. during setting or filling of a syringe
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
- A61M2005/2403—Ampoule inserted into the ampoule holder
- A61M2005/2407—Ampoule inserted into the ampoule holder from the rear
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M2005/3125—Details specific display means, e.g. to indicate dose setting
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M2005/3125—Details specific display means, e.g. to indicate dose setting
- A61M2005/3126—Specific display means related to dosing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/24—Ampoule syringes, i.e. syringes with needle for use in combination with replaceable ampoules or carpules, e.g. automatic
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31535—Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31535—Means improving security or handling thereof, e.g. blocking means, means preventing insufficient dosing, means allowing correction of overset dose
- A61M5/31541—Means preventing setting of a dose beyond the amount remaining in the cartridge
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31533—Dosing mechanisms, i.e. setting a dose
- A61M5/31545—Setting modes for dosing
- A61M5/31548—Mechanically operated dose setting member
- A61M5/31556—Accuracy improving means
- A61M5/31558—Accuracy improving means using scaling up or down transmissions, e.g. gearbox
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M5/00—Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
- A61M5/178—Syringes
- A61M5/31—Details
- A61M5/315—Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
- A61M5/31565—Administration mechanisms, i.e. constructional features, modes of administering a dose
- A61M5/31576—Constructional features or modes of drive mechanisms for piston rods
- A61M5/31583—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod
- A61M5/31585—Constructional features or modes of drive mechanisms for piston rods based on rotational translation, i.e. movement of piston rod is caused by relative rotation between the user activated actuator and the piston rod performed by axially moving actuator, e.g. an injection button
Definitions
- FIG. 6 to 10 A prior art delivery apparatus is disclosed in U.S. Pat. No. 6,004,297.
- the apparatus disclosed in FIG. 6 to 10 comprises a scale drum having an exterior thread which is guided in a helical thread provided on the inside of the outer wall of the housing.
- the scale drum is axially coupled to the driver to follow the axial movement of the driver.
- the driver further has an interior thread which engages a proximal thread on the piston rod such that when the driver is moved axially forward in the pen, the piston rod is rotated and henceforth screwed forward in the thread connection between the piston rod and the wall of the housing.
- a similar injection pen is disclosed in WO 04/078241.
- This injection pen comprises a threaded piston rod which is screwed forward in an internal threaded nut when rotated.
- a drive sleeve having a thread mating the thread of the piston rod rotates the piston rod when moved axially forward.
- the drive sleeve is releasable coupled to a dose dial sleeve which is rotated to dial up a dose.
- the dose dial sleeve is rotated out from the housing in order to set up a dose and it is rotated back to release the set dose.
- the drive sleeve is rotated together with the dose dial sleeve when a dose is set but prevented from rotation when the set dose is injected.
- the dose dial sleeve is rotated back, the user must be sure that the dose dial sleeve is free to rotate as any obstacle for the rotation will increase the pressure needed to press back the dose dial sleeve.
- a drug delivery device which eliminates disadvantages in the prior art drug delivery device. It is especially an object to provide a drug delivery device having a reduced displacement of the push button and a reduced friction making the drug delivery device more user friendly. Further it is an object to provide an injection device were all rotating parts are encapsulated.
- the dose setting member When injecting or otherwise expelling the set dose, the dose setting member is connected to the drive member and disconnected from dose indication sleeve such that an axial pressure applied to the dose setting member will be transformed to an axial movement of drive sleeve while the disconnected dose indication scale will be screwed back in the second thread.
- the pitch of the first thread is decisive for ratio of the translation of the longitudinal movement of the drive sleeve to the rotational movement of the piston rod
- the pitch of the second thread is decisive for the ratio of the translation of the longitudinal movement of the dose indication sleeve and the rotational movement of the dose indication sleeve.
- the dose setting member When setting up a dose to be expelled, the dose setting member is rotational connected to the dose indication sleeve.
- the drive sleeve which is disconnected from the dose setting member is supported by the dose indication sleeve such that it follows the axial movement of the dose setting member and the dose indication sleeve. By doing so the drive sleeve is screwed up its thread connection.
- the drive sleeve can engage directly in a thread provided on the piston rod.
- FIG. 3 shows a sectional view of the injection device of FIG. 1 with a dose set.
- FIG. 7 shows a sectional view of the injection device of FIG. 6 with no dose set
- FIG. 12 shows a perspective view of another example of an injection device.
- FIG. 17 shows a perspective view of an embodiment of the injection device disclosed in FIG. 15 and 16 .
- the push button 30 is disposed at the proximal end of the injection device 1 and connected to a dose setting member 50 by a plurality of inwardly pointing locking protrusions 51 on the proximal end of the dose setting member 50 entering depressions 31 in the proximal end of the push button 30 . This prevents rotation between the push button 30 and the dose setting member 50 .
- the two parts; push button 30 and dose setting member 50 could be coupled together in a number of alternative ways e.g. through welding or gluing as long they are rotational locked to each other.
- the push button 30 can further be provided with a colour indication e.g. for indicating the type of insulin in the injection device 1 .
- a colour indication can be made as an insert in the push button 30 .
- the dose indication sleeve 90 is provided with a number of mounting openings 93 facilitating the insertion of the dose setting member 50 in the dose indication sleeve 90 when assembling the injection device 1 .
- This click element 2150 is provided with resilient arms 2151 that engages a toothed ring 264 in the shield 260 . Further a toothed ring 2152 engages a rim of teeth 291 on the dose indication sleeve 290 .
- the user presses back the push button 230 against the force of the spring 277 whereby the teeth 233 on the push button 230 engages the teeth 265 at the proximal end of the shield 260 inrotatable locking the shield 260 and the push button 230 together.
- the drive sleeve 270 and the push button 230 is kept inrotatable by a ring of not shown teeth on the click element 2150 entering into engagement with a ring of corresponding teeth 276 on the drive sleeve 270 .
- a dose is set by rotating the push button 330 which rotates the click element 3150 . Due to engagement between the rim of teeth 3152 on the click element 3150 and the rim of teeth 391 on the inside surface of the dose indication sleeve 390 this is rotated with the push button 330 .
- the dose indication sleeve 590 is released from the dose setting member 550 as the teeth 553 moves free of the toothed rim 591 .
- the dose indication sleeve 590 is therefore free to return to its zero position down the thread 5101 as it is forced in the distal direction by the continuous pressure on the push button 530 .
Landscapes
- Health & Medical Sciences (AREA)
- Vascular Medicine (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hematology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Injection Moulding Of Plastics Or The Like (AREA)
- Chemical Or Physical Treatment Of Fibers (AREA)
- Polarising Elements (AREA)
Applications Claiming Priority (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DKPA200401881 | 2004-12-01 | ||
DKPA200401881 | 2004-12-01 | ||
EP05001213 | 2005-01-21 | ||
EP05001213.7 | 2005-01-21 | ||
DKPA200501168 | 2005-08-19 | ||
DKPA200501168 | 2005-08-19 | ||
PCT/EP2005/056313 WO2006058883A2 (en) | 2004-12-01 | 2005-11-29 | Injection device |
Related Parent Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
PCT/EP2005/056313 A-371-Of-International WO2006058883A2 (en) | 2004-12-01 | 2005-11-29 | Injection device |
Related Child Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US12/618,318 Continuation US8444606B2 (en) | 2004-12-01 | 2009-11-13 | Injection device |
Publications (1)
Publication Number | Publication Date |
---|---|
US20080287883A1 true US20080287883A1 (en) | 2008-11-20 |
Family
ID=35735433
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US11/791,397 Abandoned US20080287883A1 (en) | 2004-12-01 | 2005-11-29 | Injection Device |
US12/618,318 Expired - Fee Related US8444606B2 (en) | 2004-12-01 | 2009-11-13 | Injection device |
US13/762,623 Expired - Fee Related US9855391B2 (en) | 2004-12-01 | 2013-02-08 | Injection device |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
US12/618,318 Expired - Fee Related US8444606B2 (en) | 2004-12-01 | 2009-11-13 | Injection device |
US13/762,623 Expired - Fee Related US9855391B2 (en) | 2004-12-01 | 2013-02-08 | Injection device |
Country Status (7)
Country | Link |
---|---|
US (3) | US20080287883A1 (ja) |
EP (2) | EP2047878B1 (ja) |
JP (1) | JP5178202B2 (ja) |
CN (1) | CN101068586B (ja) |
AT (2) | ATE499130T1 (ja) |
DE (2) | DE602005026595D1 (ja) |
WO (1) | WO2006058883A2 (ja) |
Cited By (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20060184117A1 (en) * | 2005-01-18 | 2006-08-17 | Barry Knight | Pen shaped medication injection devices |
WO2010140974A1 (en) | 2009-06-05 | 2010-12-09 | Shl Group Ab | Medicament delivery device |
US20100324494A1 (en) * | 2009-06-01 | 2010-12-23 | Sanofi-Aventis Deutschland Gmbh | Drug delivery device last dose lock-out mechanism |
WO2011039236A1 (en) * | 2009-09-30 | 2011-04-07 | Sanofi-Aventis Deutschland Gmbh | Resettable drive assembly and drug delivery device |
US20110092905A1 (en) * | 2009-10-16 | 2011-04-21 | Owen Mumford Limited | Injector apparatus |
WO2011073307A1 (en) * | 2009-12-18 | 2011-06-23 | Sanofi-Aventis Deutschland Gmbh | Piston for a cartridge and piston rod for a drug delivery device |
US20120197213A1 (en) * | 2006-09-15 | 2012-08-02 | Philippe Kohlbrenner | Injection device comprising several coupling mechanisms |
US20130197478A1 (en) * | 2010-10-13 | 2013-08-01 | Sanofi-Aventis Deutschland Gmbh | Dose setting mechanism and method of using same |
US20130211331A1 (en) * | 2010-06-11 | 2013-08-15 | Sanofi-Aventis Deutschland Gmbh | Drive assembly, drive component and drug delivery device |
US20140236096A1 (en) * | 2011-09-29 | 2014-08-21 | Sanofi-Aventis Deutschland Gmbh | Drug Delivery Device and Method for a Drug Delivery Device |
WO2015145294A1 (en) | 2014-03-25 | 2015-10-01 | Wockhardt Limited | Fluid delivery pen with final dose stop and improved dose setting features |
US20150290397A1 (en) * | 2011-10-17 | 2015-10-15 | Shl Group Ab | Medicament Delivery Device |
US20160045665A1 (en) * | 2013-04-10 | 2016-02-18 | Sanofi | Drive Mechanism for a Drug Delivery Device |
US20160045672A1 (en) * | 2013-04-10 | 2016-02-18 | Sanofi | Injection Device and Assembly Method |
US20160067416A1 (en) * | 2013-05-27 | 2016-03-10 | Sanofi-Aventis Deutschland Gmbh | Assembly for a drug delivery device and drug delivery device |
US9352097B2 (en) | 2009-06-01 | 2016-05-31 | Sanofi-Aventis Deutschland Gmbh | Spindle for a drug delivery device |
US9724475B2 (en) | 2009-02-27 | 2017-08-08 | Lifescan, Inc. | Drug delivery management systems and methods |
US20180001031A1 (en) * | 2014-02-05 | 2018-01-04 | Haselmeier Ag | Injection device |
US9931472B2 (en) | 2012-04-17 | 2018-04-03 | Universiteit Antwerpen | Intradermal injection device |
JP2019520150A (ja) * | 2016-07-01 | 2019-07-18 | サノフイSanofi | 薬物送達デバイス |
US10518035B2 (en) | 2012-05-16 | 2019-12-31 | Tecpharma Licensing Ag | Device for adjusting a dosage with a limiting mechanism for a device for administering a product |
US11351307B2 (en) * | 2016-11-07 | 2022-06-07 | Beloteca Investment Fund 1, LLC | Adjustable dose drug delivery system |
US11400227B2 (en) * | 2017-04-07 | 2022-08-02 | Novo Nordisk A/S | End-of-content mechanism |
US11413405B2 (en) | 2016-04-01 | 2022-08-16 | Idevax Bv | Injection device |
US11426524B2 (en) * | 2008-12-22 | 2022-08-30 | Ypsomed Ag | Dose setting device for an injection device |
CN115282404A (zh) * | 2022-08-16 | 2022-11-04 | 山东威高普瑞医药包装有限公司 | 一种可调剂量医用注射笔 |
US11565047B2 (en) | 2017-01-09 | 2023-01-31 | Verily Life Sciences Llc | Wearable non-liquid medication injection device |
Families Citing this family (68)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20040098010A1 (en) * | 2001-10-22 | 2004-05-20 | Glenn Davison | Confuser crown skin pricker |
GB0304822D0 (en) | 2003-03-03 | 2003-04-09 | Dca Internat Ltd | Improvements in and relating to a pen-type injector |
EP2047878B1 (en) | 2004-12-01 | 2011-02-23 | Novo Nordisk A/S | Injection Device |
RU2407557C2 (ru) | 2005-07-27 | 2010-12-27 | Ново Нордиск А/С | Инъекционное устройство с механизмом ограничения дозы и предохранительным механизмом |
ATE499962T1 (de) | 2005-07-27 | 2011-03-15 | Novo Nordisk As | Dosismechanismus für ein injektionsgerät zur begrenzung einer dosiseinstellung entsprechend der verbleibenden arzneimenge |
GB0524604D0 (en) * | 2005-12-02 | 2006-01-11 | Owen Mumford Ltd | Injection method and apparatus |
GB2434103B (en) * | 2006-01-12 | 2009-11-25 | Owen Mumford Ltd | Lancet firing device |
EP2019701B1 (en) | 2006-05-16 | 2010-02-24 | Novo Nordisk A/S | A gearing mechanism for an injection device |
CA2564061A1 (en) * | 2006-10-16 | 2008-04-16 | Duoject Medical Systems Inc. | Reconstitution system for mixing the contents of a vial containing a first substance with a second substance stored in a cartridge |
DE102007026083A1 (de) | 2007-05-25 | 2008-11-27 | Haselmeier S.A.R.L. | Injektionsgerät |
DK2234661T3 (da) | 2007-12-20 | 2013-07-15 | Novo Nordisk As | Injektionsindretning til levering af en fast dosis flydende medicin |
EP2274029B1 (en) | 2008-05-02 | 2011-11-02 | Sanofi-Aventis Deutschland GmbH | Medication delivery device |
AU2009242700B2 (en) † | 2008-05-02 | 2012-02-23 | Sanofi-Aventis Deutschland Gmbh | Medication delivery device |
US9125986B2 (en) * | 2008-12-12 | 2015-09-08 | Shl Group Ab | Medicament delivery device |
WO2010112558A1 (en) * | 2009-03-31 | 2010-10-07 | Sanofi-Aventis Deutschland Gmbh | Drug delivery device with dose indication window |
US8529503B2 (en) * | 2009-04-24 | 2013-09-10 | Shl Group Ab | Medicament delivery device |
US8974423B2 (en) | 2009-06-01 | 2015-03-10 | Sanofi-Aventis Deutschland Gmbh | Resettable drug delivery device |
US9457150B2 (en) | 2009-06-01 | 2016-10-04 | Sanofi-Aventis Deutschland Gmbh | Biasing mechanism for a drug delivery device |
US9238106B2 (en) * | 2009-06-01 | 2016-01-19 | Sanofi-Aventis Deutschland Gmbh | Dose setting mechanism for priming a drug delivery device |
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Also Published As
Publication number | Publication date |
---|---|
WO2006058883A3 (en) | 2006-09-08 |
WO2006058883A2 (en) | 2006-06-08 |
CN101068586A (zh) | 2007-11-07 |
ATE499130T1 (de) | 2011-03-15 |
JP2008521534A (ja) | 2008-06-26 |
US9855391B2 (en) | 2018-01-02 |
US20100179485A1 (en) | 2010-07-15 |
CN101068586B (zh) | 2011-05-25 |
EP2047878A1 (en) | 2009-04-15 |
DE602005026595D1 (de) | 2011-04-07 |
JP5178202B2 (ja) | 2013-04-10 |
EP1827538B1 (en) | 2009-08-12 |
ATE439156T1 (de) | 2009-08-15 |
EP1827538B2 (en) | 2015-07-01 |
DE602005016011D1 (de) | 2009-09-24 |
EP2047878B1 (en) | 2011-02-23 |
US20130150799A1 (en) | 2013-06-13 |
EP1827538A2 (en) | 2007-09-05 |
US8444606B2 (en) | 2013-05-21 |
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